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CERTIFICATION
In connection with the Quarterly Report on Form 10-Q of Helicos BioSciences Corporation (the "Company") for the period ended September 30, 2008 as filed with the Securities and Exchange Commission on the date hereof (the "Report"), we Stephen J. Lombardi, the Principal Executive Officer of the Company and Stephen P. Hall, the Principal Financial and Accounting Officer of the Company, hereby certify, pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to our knowledge that:
- (1)
- the Report fully complies with the requirements of Section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended, and
- (2)
- the information in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.
| Dated: November 14, 2008 | /s/ STEPHEN J. LOMBARDI Stephen J. Lombardi President and Chief Executive Officer (Principal Executive Officer) | |
Dated: November 14, 2008 | /s/ STEPHEN P. HALL Stephen P. Hall Senior Vice President and Chief Financial Officer (Principal Financial and Accounting Officer) |