March 31, 2011
VIA EDGAR AND FACSIMILE
United States Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549-3561
Attention: John L. Krug
RE: | Tranzyme, Inc. |
| Common Stock |
| Form S-1 File No. 333-170749 |
Ladies and Gentlemen:
In connection with the proposed offering of the above-captioned Securities, we wish to advise you that we hereby join with the Registrant’s request that the effective date of the above-captioned Registration Statement be accelerated so that the same will become effective on April 1, 2011 at 11:00 a.m. or as soon as practicable thereafter.
Supplemental information supplied under Rule 418(a)(7) under the Securities Act of 1933:
(i) | Date of Preliminary Prospectus: March 8, 2011 |
(ii) | Dates of distribution: from March 8, 2011 to the date hereof |
(iii) | Number of prospective underwriters: 4 |
(iv) | Number of prospectuses distributed under (iii) above: 6,485 |
(v) | Compliance with Rule 15c2-8 under the Securities Exchange Act of 1934: Included in Master Agreement Among Underwriters of Salomon Smith Barney Inc. (now known as Citigroup Global Markets Inc.). |
Very truly yours, |
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Citigroup Global Markets Inc. |
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/s/ Kristian Humer |
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Kristian Humer |
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Vice President |
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