Clough Capital Partners L P 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
Estimated average burden
hours per response:		23.8

COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
1LIFE HEALTHCARE INC	COM	68269G107	18,696	478,400	SH		DFND	1	478,400	0	0
21VIANET GROUP INC	SPONSORED ADS A	90138A103	384	11,900	SH		DFND	1	11,900	0	0
ABBVIE INC	COM	00287Y109	9,046	83,590	SH		DFND	1	83,590	0	0
ABCELLERA BIOLOGICS INC	COM	00288U106	16,113	474,484	SH		DFND	1	474,484	0	0
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	21,216	371,300	SH		DFND	1	371,300	0	0
AGNC INVT CORP	COM	00123Q104	37,797	2,255,200	SH		DFND	1	2,255,200	0	0
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	4,137	18,247	SH		DFND	1	18,247	0	0
ALPHABET INC	CAP STK CL C	02079K107	22,887	11,064	SH		DFND	1	11,064	0	0
AMAZON COM INC	COM	023135106	6,095	1,970	SH		DFND	1	1,970	0	0
ANNALY CAPITAL MANAGEMENT IN	COM	035710409	48,621	5,653,600	SH		DFND	1	5,653,600	0	0
ANTHEM INC	COM	036752103	26,912	74,975	SH		DFND	1	74,975	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	20,989	489,149	SH		DFND	1	489,149	0	0
APOLLO SR FLOATING RATE FD I	COM	037636107	204	13,761	SH		DFND	1	13,761	0	0
APPLIED MATLS INC	COM	038222105	35,045	262,310	SH		DFND	1	262,310	0	0
ARES CAPITAL CORP	NOTE 3.750% 2/0	04010LAT0	3,096	3,000,000	PRN		DFND	1	3,000,000	0	0
AVEO PHARMACEUTICALS INC	COM NEW	053588307	2,196	300,000	SH		DFND	1	300,000	0	0
BAIDU INC	SPON ADR REP A	056752108	653	3,000	SH		DFND	1	3,000	0	0
BARINGS BDC INC	COM	06759L103	12,613	1,263,826	SH		DFND	1	1,263,826	0	0
BAXTER INTL INC	COM	071813109	6,005	71,200	SH		DFND	1	71,200	0	0
BILIBILI INC	SPONS ADS REP Z	090040106	653	6,100	SH		DFND	1	6,100	0	0
BK OF AMERICA CORP	COM	060505104	38,877	1,004,823	SH		DFND	1	1,004,823	0	0
BLACKROCK HEALTH SCIENCS TR	COM SHS	09260E105	2,733	103,900	SH		DFND	1	103,900	0	0
BLACKROCK RES & COMMODITIES	SHS	09257A108	490	55,287	SH		DFND	1	55,287	0	0
BOOKING HOLDINGS INC	COM	09857L108	22,832	9,800	SH	Call	DFND	1	9,800	0	0
BOOKING HOLDINGS INC	COM	09857L108	28,161	12,087	SH		DFND	1	12,087	0	0
BRANDYWINEGBL GBL INCM OPP F	COM	10537L104	709	58,816	SH		DFND	1	58,816	0	0
BROADCOM INC	COM	11135F101	21,968	47,380	SH		DFND	1	47,380	0	0
CALAMOS CONV OPPORTUNITIES &	SH BEN INT	128117108	919	64,600	SH		DFND	1	64,600	0	0
CALAMOS LNG SHR EQT DYNAMIC	COM	12812C106	1,704	84,435	SH		DFND	1	84,435	0	0
CARNIVAL CORP	UNIT 99/99/9999	143658300	38,043	1,433,440	SH		DFND	1	1,433,440	0	0
CARVANA CO	CL A	146869102	17,808	67,864	SH		DFND	1	67,864	0	0
CENTER COAST BRKFLD MLP ENRG	SHS BEN INT	151461209	581	53,064	SH		DFND	1	53,064	0	0
CENTRAL SECS CORP	COM	155123102	1,288	33,986	SH		DFND	1	33,986	0	0
CHECKMATE PHARMACEUTICALS IN	COM	162818108	16,417	1,352,313	SH		DFND	1	1,352,313	0	0
CITIGROUP INC	COM NEW	172967424	29,972	411,990	SH		DFND	1	411,990	0	0
COHEN & STEERS MLP INCOME &	COM SHS	19249B106	2,891	903,467	SH		DFND	1	903,467	0	0
COMMUNITY HEALTHCARE TR INC	COM	20369C106	14,710	318,959	SH		DFND	1	318,959	0	0
COVETRUS INC	COM	22304C100	12,351	412,100	SH		DFND	1	412,100	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	13,282	109,000	SH	Call	DFND	1	109,000	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	22,783	186,977	SH		DFND	1	186,977	0	0
CROWDSTRIKE HLDGS INC	CL A	22788C105	6,240	34,190	SH		DFND	1	34,190	0	0
D R HORTON INC	COM	23331A109	25,533	286,500	SH		DFND	1	286,500	0	0
DBX ETF TR	XTRACK HRVST CSI	233051879	5,063	131,100	SH		DFND	1	131,100	0	0
DELAWARE ENHANCED GBL DIV &	COM	246060107	1,034	105,426	SH		DFND	1	105,426	0	0
DISNEY WALT CO	COM	254687106	20,519	111,200	SH	Call	DFND	1	111,200	0	0
DISNEY WALT CO	COM	254687106	26,084	141,360	SH		DFND	1	141,360	0	0
DUFF & PHELPS SLT ENGY AND M	COM NEW	26433F207	589	80,070	SH		DFND	1	80,070	0	0
DYNATRACE INC	COM NEW	268150109	8,817	182,780	SH		DFND	1	182,780	0	0
EATON VANCE FLTG RATE INCOM	COM SHS BEN INT	278284104	2,446	150,234	SH		DFND	1	150,234	0	0
EATON VANCE FLTING RATE INC	COM	278279104	277	19,664	SH		DFND	1	19,664	0	0
EATON VANCE SR INCOME TR	SH BEN INT	27826S103	155	23,448	SH		DFND	1	23,448	0	0
EQUITABLE HLDGS INC	COM	29452E101	35,954	1,102,200	SH		DFND	1	1,102,200	0	0
FIRST AMERN FINL CORP	COM	31847R102	44,493	785,400	SH		DFND	1	785,400	0	0
FIRST EAGLE SENIOR LOAN FUND	COM NEW	32010E100	876	61,100	SH		DFND	1	61,100	0	0
FIRST TR SR FLG RTE INCM FD	COM	33733U108	200	16,300	SH		DFND	1	16,300	0	0
FLEXION THERAPEUTICS INC	COM	33938J106	5,929	662,406	SH		DFND	1	662,406	0	0
GABELLI UTIL TR	RIGHT 04/14/2021	36240A168	22	201,400	SH		DFND	1	201,400	0	0
GDS HLDGS LTD	SPONSORED ADS	36165L108	288	3,552	SH		DFND	1	3,552	0	0
GOLUB CAP BDC INC	COM	38173M102	12,078	826,125	SH		DFND	1	826,125	0	0
GOSSAMER BIO INC	COM	38341P102	4,242	458,634	SH		DFND	1	458,634	0	0
GOSSAMER BIO INC	NOTE 5.000% 6/0	38341PAA0	3,190	3,500,000	PRN		DFND	1	3,500,000	0	0
GUGGENHEIM ENHANCED EQUITY I	COM	40167B100	212	29,365	SH		DFND	1	29,365	0	0
HANCOCK JOHN INVT TR	TAX ADV GLB SH	41013P749	555	86,430	SH		DFND	1	86,430	0	0
HERCULES CAPITAL INC	DBCV 4.375% 2/0	427096AF9	31	30,000	PRN		DFND	1	30,000	0	0
HERZFELD CARIBBEAN BASIN FD	COM	42804T106	450	76,501	SH		DFND	1	76,501	0	0
HIGHLAND GLOBAL ALLOCATION F	COM	43010T104	3,414	442,756	SH		DFND	1	442,756	0	0
HIGHLAND INCOME FD	HIGHLAND INCOME	43010E404	2,967	267,533	SH		DFND	1	267,533	0	0
HOLOGIC INC	COM	436440101	15,696	211,020	SH		DFND	1	211,020	0	0
HUMANA INC	COM	444859102	26,838	64,015	SH		DFND	1	64,015	0	0
INTEL CORP	COM	458140100	20,096	314,000	SH		DFND	1	314,000	0	0
INVESCO DYNAMIC CR OPPORTUNI	COM	46132R104	1,320	116,100	SH		DFND	1	116,100	0	0
INVESCO QQQ TR	UNIT SER 1	46090E103	367,000	1,150,000	SH	Put	DFND	1	1,150,000	0	0
ISHARES TR	NASDAQ BIOTECH	464287556	29,254	194,300	SH	Put	DFND	1	194,300	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	20,510	124,780	SH		DFND	1	124,780	0	0
JD.COM INC	SPON ADR CL A	47215P106	1,012	12,000	SH		DFND	1	12,000	0	0
JOHNSON & JOHNSON	COM	478160104	26,260	159,780	SH		DFND	1	159,780	0	0
JPMORGAN CHASE & CO	COM	46625H100	26,861	176,450	SH		DFND	1	176,450	0	0
KURA ONCOLOGY INC	COM	50127T109	717	25,361	SH		DFND	1	25,361	0	0
LAM RESEARCH CORP	COM	512807108	26,030	43,730	SH		DFND	1	43,730	0	0
LENNAR CORP	CL A	526057104	26,016	256,999	SH		DFND	1	256,999	0	0
LILLY ELI & CO	COM	532457108	1,721	9,213	SH		DFND	1	9,213	0	0
LYFT INC	CL A COM	55087P104	26,174	414,270	SH		DFND	1	414,270	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	35,995	101,094	SH		DFND	1	101,094	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	39,664	111,400	SH	Call	DFND	1	111,400	0	0
MCKESSON CORP	COM	58155Q103	28,633	146,805	SH		DFND	1	146,805	0	0
MCKESSON CORP	COM	58155Q103	39,047	200,200	SH	Call	DFND	1	200,200	0	0
MERCK & CO. INC	COM	58933Y105	17,754	230,300	SH		DFND	1	230,300	0	0
MICRON TECHNOLOGY INC	COM	595112103	38,724	439,000	SH		DFND	1	439,000	0	0
MICROSOFT CORP	COM	594918104	4,576	19,409	SH		DFND	1	19,409	0	0
MILLER HOWARD HIGH INC EQTY	COM SHS BEN IN	600379101	1,917	199,700	SH		DFND	1	199,700	0	0
MIRATI THERAPEUTICS INC	COM	60468T105	2,622	15,305	SH		DFND	1	15,305	0	0
MODERNA INC	COM	60770K107	4,704	35,922	SH		DFND	1	35,922	0	0
NETEASE INC	SPONSORED ADS	64110W102	880	8,525	SH		DFND	1	8,525	0	0
NEXPOINT STRATEGIC OPPORTES	COM NEW	65340G205	619	54,358	SH		DFND	1	54,358	0	0
NUVEEN CORE EQUITY ALPHA FD	COM	67090X107	2,277	149,700	SH		DFND	1	149,700	0	0
NUVEEN DIVERSIFIED DIVID & I	COM	6706EP105	388	40,900	SH		DFND	1	40,900	0	0
NUVEEN FLOATING RATE INCOME	COM	67072T108	708	73,244	SH		DFND	1	73,244	0	0
NUVEEN FLTNG RTE INCM OPP FD	COM SHS	6706EN100	388	40,700	SH		DFND	1	40,700	0	0
NUVEEN REAL ASSET INCOME & G	COM	67074Y105	225	15,293	SH		DFND	1	15,293	0	0
NUVEEN SHT DUR CR OPP FD	COM	67074X107	385	27,300	SH		DFND	1	27,300	0	0
NUVEEN TAX-ADVANTAGED DIVID	COM	67073G105	695	46,000	SH		DFND	1	46,000	0	0
PENNYMAC FINL SVCS INC NEW	COM	70932M107	49,531	740,701	SH		DFND	1	740,701	0	0
PFIZER INC	COM	717081103	26,752	738,400	SH		DFND	1	738,400	0	0
PHYSICIANS RLTY TR	COM	71943U104	8,519	482,100	SH		DFND	1	482,100	0	0
PINDUODUO INC	SPONSORED ADS	722304102	496	3,708	SH		DFND	1	3,708	0	0
REDWOOD TR INC	COM	758075402	5,891	565,900	SH		DFND	1	565,900	0	0
REDWOOD TR INC	NOTE 4.750% 8/1	758075AC9	1,974	1,978,000	PRN		DFND	1	1,978,000	0	0
REPARE THERAPEUTICS INC	COM	760273102	9,946	324,079	SH		DFND	1	324,079	0	0
ROYAL CARIBBEAN GROUP	COM	V7780T103	39,616	462,747	SH		DFND	1	462,747	0	0
SALIENT MIDSTREAM & MLP FD	SH BEN INT	79471V105	953	186,772	SH		DFND	1	186,772	0	0
SIX FLAGS ENTMT CORP NEW	COM	83001A102	9,294	200,000	SH	Call	DFND	1	200,000	0	0
SIX FLAGS ENTMT CORP NEW	COM	83001A102	17,245	371,100	SH		DFND	1	371,100	0	0
SIXTH STREET SPECIALTY LENDN	COM	83012A109	15,620	742,727	SH		DFND	1	742,727	0	0
SMART GLOBAL HLDGS INC	SHS	G8232Y101	11,160	242,500	SH		DFND	1	242,500	0	0
SPLUNK INC	COM	848637104	3,765	27,790	SH		DFND	1	27,790	0	0
STARWOOD PPTY TR INC	NOTE 4.375% 4/0	85571BAH8	11,314	10,815,000	PRN		DFND	1	10,815,000	0	0
TAIWAN SEMICONDUCTOR MFG LTD	SPONSORED ADS	874039100	9,202	77,800	SH		DFND	1	77,800	0	0
TELADOC HEALTH INC	COM	87918A105	1,562	8,592	SH		DFND	1	8,592	0	0
TEMPLETON GLOBAL INCOME FD	COM	880198106	1,199	225,831	SH		DFND	1	225,831	0	0
TESLA INC	COM	88160R101	8,924	13,360	SH		DFND	1	13,360	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	21,697	47,542	SH		DFND	1	47,542	0	0
THERMO FISHER SCIENTIFIC INC	COM	883556102	44,634	97,800	SH	Call	DFND	1	97,800	0	0
TRANSDIGM GROUP INC	COM	893641100	26,809	45,600	SH	Call	DFND	1	45,600	0	0
TRANSDIGM GROUP INC	COM	893641100	30,287	51,516	SH		DFND	1	51,516	0	0
TWILIO INC	CL A	90138F102	6,444	18,910	SH		DFND	1	18,910	0	0
TWO HBRS INVT CORP	NOTE 6.250% 1/1	90187BAA9	2,352	2,299,000	PRN		DFND	1	2,299,000	0	0
UBER TECHNOLOGIES INC	COM	90353T100	27,353	501,800	SH		DFND	1	501,800	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	24,036	64,600	SH		DFND	1	64,600	0	0
UNIVERSAL HLTH SVCS INC	CL B	913903100	22,921	171,835	SH		DFND	1	171,835	0	0
VERACYTE INC	COM	92337F107	6,203	115,400	SH	Call	DFND	1	115,400	0	0
VERACYTE INC	COM	92337F107	8,861	164,860	SH		DFND	1	164,860	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	17,466	81,280	SH		DFND	1	81,280	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	77,898	362,500	SH	Call	DFND	1	362,500	0	0
VIRTUS GLOBAL DIVID & INCOME	COM	92835W107	1,513	164,476	SH		DFND	1	164,476	0	0
VIRTUS GLOBAL MULTI-SECTOR I	COM	92829B101	206	17,332	SH		DFND	1	17,332	0	0
VISA INC	COM CL A	92826C839	18,922	89,370	SH		DFND	1	89,370	0	0
VOYA GLBL ADV & PREM OPP FD	COM	92912R104	974	101,739	SH		DFND	1	101,739	0	0
VOYA INFRASTRUCTURE INDLS &	COM	92912X101	774	62,508	SH		DFND	1	62,508	0	0
VOYA INTL HIGH DIV EQTY INM	COM	92912Y109	1,343	240,722	SH		DFND	1	240,722	0	0
VOYA NAT RES EQUITY INCOME F	COM	92913C106	3,315	1,001,500	SH		DFND	1	1,001,500	0	0
WELLS FARGO GLOBAL DIVID OPP	COM	94987C103	965	183,445	SH		DFND	1	183,445	0	0
ZAI LAB LTD	ADR	98887Q104	12,330	92,410	SH		DFND	1	92,410	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	2,364	14,765	SH		DFND	1	14,765	0	0
ZOETIS INC	CL A	98978V103	18,741	119,005	SH		DFND	1	119,005	0	0