| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 |
| | | VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY |
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACADIA HEALTHCARE COMPANY IN | COM | 00404A109 | 9,974 | 164,320 | SH | | DFND | 1 | 164,320 | 0 | 0 |
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 652 | 5,491 | SH | | DFND | 1 | 5,491 | 0 | 0 |
| ALPHABET INC | CAP STK CL C | 02079K107 | 8,574 | 2,963 | SH | | DFND | 1 | 2,963 | 0 | 0 |
| AMAZON COM INC | COM | 023135106 | 89,590 | 26,869 | SH | | DFND | 1 | 26,869 | 0 | 0 |
| APELLIS PHARMACEUTICALS INC | COM | 03753U106 | 6,229 | 131,749 | SH | | DFND | 1 | 131,749 | 0 | 0 |
| ARVINAS INC | COM | 04335A105 | 18,835 | 229,300 | SH | | DFND | 1 | 229,300 | 0 | 0 |
| BARINGS BDC INC | COM | 06759L103 | 8,815 | 799,916 | SH | | DFND | 1 | 799,916 | 0 | 0 |
| BILL COM HLDGS INC | COM | 090043100 | 19,670 | 78,950 | SH | | DFND | 1 | 78,950 | 0 | 0 |
| BLACKROCK ESG CAP ALLC TR | SHS BEN INT | 09262F100 | 873 | 46,800 | SH | | DFND | 1 | 46,800 | 0 | 0 |
| BLACKROCK INNOVATION AND GRW | SHS BEN INT | 09260Q108 | 2,766 | 190,264 | SH | | DFND | 1 | 190,264 | 0 | 0 |
| BLACKSTONE SECD LENDING FD | COMMON STOCK | 09261X102 | 3,920 | 115,305 | SH | | DFND | 1 | 115,305 | 0 | 0 |
| BOEING CO | COM | 097023105 | 12,512 | 62,150 | SH | | DFND | 1 | 62,150 | 0 | 0 |
| BOULDER GROWTH & INCOME FD I | COM | 101507101 | 1,198 | 84,312 | SH | | DFND | 1 | 84,312 | 0 | 0 |
| BRANDYWINEGBL GBL INCM OPP F | COM | 10537L104 | 315 | 26,880 | SH | | DFND | 1 | 26,880 | 0 | 0 |
| BROOKDALE SR LIVING INC | COM | 112463104 | 931 | 180,399 | SH | | DFND | 1 | 180,399 | 0 | 0 |
| C4 THERAPEUTICS INC | COM STK | 12529R107 | 8,233 | 255,681 | SH | | DFND | 1 | 255,681 | 0 | 0 |
| CARNIVAL CORP | COMMON STOCK | 143658300 | 7,385 | 367,070 | SH | | DFND | 1 | 367,070 | 0 | 0 |
| CARVANA CO | CL A | 146869102 | 18,536 | 79,969 | SH | | DFND | 1 | 79,969 | 0 | 0 |
| CENTER COAST BRKFLD MLP ENRG | SHS BEN INT | 151461209 | 1,455 | 107,485 | SH | | DFND | 1 | 107,485 | 0 | 0 |
| CHECKMATE PHARMACEUTICALS IN | COM | 162818108 | 3,750 | 1,306,626 | SH | | DFND | 1 | 1,306,626 | 0 | 0 |
| CISCO SYS INC | COM | 17275R102 | 4,037 | 63,700 | SH | | DFND | 1 | 63,700 | 0 | 0 |
| COHEN & STEERS REIT & PFD & | COM | 19247X100 | 487 | 17,000 | SH | | DFND | 1 | 17,000 | 0 | 0 |
| COMMUNITY HEALTH SYS INC NEW | COM | 203668108 | 13,628 | 1,023,859 | SH | | DFND | 1 | 1,023,859 | 0 | 0 |
| COMMUNITY HEALTHCARE TR INC | COM | 20369C106 | 3,295 | 69,700 | SH | | DFND | 1 | 69,700 | 0 | 0 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 6,123 | 80,800 | SH | Call | DFND | 1 | 80,800 | 0 | 0 |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 8,033 | 106,007 | SH | | DFND | 1 | 106,007 | 0 | 0 |
| CUSHING MLP & INFRASTRUCT | COM NEW | 231631300 | 1,132 | 37,100 | SH | | DFND | 1 | 37,100 | 0 | 0 |
| D R HORTON INC | COM | 23331A109 | 48,510 | 447,300 | SH | | DFND | 1 | 447,300 | 0 | 0 |
| DBX ETF TR | XTRACK HRVST CSI | 233051879 | 5,125 | 131,100 | SH | | DFND | 1 | 131,100 | 0 | 0 |
| DELAWARE IVY HIGH INCOME OPP | COM | 246107106 | 518 | 37,200 | SH | | DFND | 1 | 37,200 | 0 | 0 |
| DOUBLELINE INCOME SOLUTIONS | COM | 258622109 | 1,033 | 64,100 | SH | | DFND | 1 | 64,100 | 0 | 0 |
| DOXIMITY INC | CL A | 26622P107 | 16,307 | 325,300 | SH | | DFND | 1 | 325,300 | 0 | 0 |
| EATON VANCE ENHANCED EQUITY | COM | 278277108 | 270 | 11,000 | SH | | DFND | 1 | 11,000 | 0 | 0 |
| EATON VANCE TAX ADVT DIV INC | COM | 27828G107 | 283 | 9,500 | SH | | DFND | 1 | 9,500 | 0 | 0 |
| EATON VANCE TX ADV GLBL DIV | COM | 27828S101 | 223 | 9,806 | SH | | DFND | 1 | 9,806 | 0 | 0 |
| EQUITABLE HLDGS INC | COM | 29452E101 | 40,473 | 1,234,300 | SH | | DFND | 1 | 1,234,300 | 0 | 0 |
| FIDELITY NATIONAL FINANCIAL | FNF GROUP COM | 31620R303 | 57,252 | 1,097,200 | SH | | DFND | 1 | 1,097,200 | 0 | 0 |
| FIRST AMERN FINL CORP | COM | 31847R102 | 70,409 | 900,030 | SH | | DFND | 1 | 900,030 | 0 | 0 |
| FIVE9 INC | COM | 338307101 | 21,495 | 156,530 | SH | | DFND | 1 | 156,530 | 0 | 0 |
| FRANKLIN UNVL TR | SH BEN INT | 355145103 | 177 | 20,937 | SH | | DFND | 1 | 20,937 | 0 | 0 |
| GODADDY INC | CL A | 380237107 | 11,032 | 130,000 | SH | | DFND | 1 | 130,000 | 0 | 0 |
| GOSSAMER BIO INC | NOTE 5.000% 6/0 | 38341PAA0 | 3,333 | 3,500,000 | PRN | | DFND | 1 | 3,500,000 | 0 | 0 |
| GUGGENHEIM STRATEGIC OPPORTU | COM SBI | 40167F101 | 2,923 | 159,528 | SH | | DFND | 1 | 159,528 | 0 | 0 |
| HCA HEALTHCARE INC | COM | 40412C101 | 9,318 | 36,270 | SH | | DFND | 1 | 36,270 | 0 | 0 |
| HERTZ GLOBAL HLDGS INC | COM NEW | 42806J700 | 4,971 | 198,900 | SH | | DFND | 1 | 198,900 | 0 | 0 |
| HERTZ GLOBAL HLDGS INC | W EXP 06/30/205 | 42806J148 | 12,655 | 793,400 | SH | | DFND | 1 | 793,400 | 0 | 0 |
| HERZFELD CARIBBEAN BASIN FD | COM | 42804T106 | 112 | 20,213 | SH | | DFND | 1 | 20,213 | 0 | 0 |
| HIGH INCOME SECS FD | SHS BEN INT | 42968F108 | 273 | 31,510 | SH | | DFND | 1 | 31,510 | 0 | 0 |
| HIGHLAND GLOBAL ALLOCATION F | COM | 43010T104 | 838 | 92,400 | SH | | DFND | 1 | 92,400 | 0 | 0 |
| HOLOGIC INC | COM | 436440101 | 17,457 | 228,020 | SH | | DFND | 1 | 228,020 | 0 | 0 |
| HUBSPOT INC | COM | 443573100 | 16,518 | 25,060 | SH | | DFND | 1 | 25,060 | 0 | 0 |
| IRHYTHM TECHNOLOGIES INC | COM | 450056106 | 11,225 | 95,375 | SH | | DFND | 1 | 95,375 | 0 | 0 |
| JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 19,453 | 152,690 | SH | | DFND | 1 | 152,690 | 0 | 0 |
| JD.COM INC | SPON ADR CL A | 47215P106 | 799 | 11,400 | SH | | DFND | 1 | 11,400 | 0 | 0 |
| JOHNSON & JOHNSON | COM | 478160104 | 26,360 | 154,090 | SH | | DFND | 1 | 154,090 | 0 | 0 |
| KB HOME | COM | 48666K109 | 10,847 | 242,500 | SH | | DFND | 1 | 242,500 | 0 | 0 |
| KYMERA THERAPEUTICS INC | COM | 501575104 | 17,206 | 271,000 | SH | | DFND | 1 | 271,000 | 0 | 0 |
| LAM RESEARCH CORP | COM | 512807108 | 45,529 | 63,310 | SH | | DFND | 1 | 63,310 | 0 | 0 |
| LEGEND BIOTECH CORP | SPONSORED ADS | 52490G102 | 9,091 | 195,052 | SH | | DFND | 1 | 195,052 | 0 | 0 |
| LENNAR CORP | CL A | 526057104 | 36,004 | 309,949 | SH | | DFND | 1 | 309,949 | 0 | 0 |
| LIBERTY ALL STAR EQUITY FD | SH BEN INT | 530158104 | 1,793 | 213,952 | SH | | DFND | 1 | 213,952 | 0 | 0 |
| LILLY ELI & CO | COM | 532457108 | 3,318 | 12,013 | SH | | DFND | 1 | 12,013 | 0 | 0 |
| MCKESSON CORP | COM | 58155Q103 | 18,225 | 73,320 | SH | | DFND | 1 | 73,320 | 0 | 0 |
| MERCK & CO INC | COM | 58933Y105 | 20,271 | 264,500 | SH | | DFND | 1 | 264,500 | 0 | 0 |
| MICRON TECHNOLOGY INC | COM | 595112103 | 83,025 | 891,300 | SH | | DFND | 1 | 891,300 | 0 | 0 |
| MICROSOFT CORP | COM | 594918104 | 77,848 | 231,470 | SH | | DFND | 1 | 231,470 | 0 | 0 |
| MILLER HOWARD HIGH INC EQTY | COM SHS BEN IN | 600379101 | 3,382 | 327,704 | SH | | DFND | 1 | 327,704 | 0 | 0 |
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 14,736 | 100,455 | SH | | DFND | 1 | 100,455 | 0 | 0 |
| NETEASE INC | SPONSORED ADS | 64110W102 | 427 | 4,200 | SH | | DFND | 1 | 4,200 | 0 | 0 |
| NEUBERGER BERMAN NEXT GENERA | COMMON STOCK | 64133Q108 | 3,559 | 205,700 | SH | | DFND | 1 | 205,700 | 0 | 0 |
| NURIX THERAPEUTICS INC | COM | 67080M103 | 13,695 | 473,048 | SH | | DFND | 1 | 473,048 | 0 | 0 |
| OXFORD LANE CAP CORP | COM | 691543102 | 886 | 114,900 | SH | | DFND | 1 | 114,900 | 0 | 0 |
| PENNYMAC FINL SVCS INC NEW | COM | 70932M107 | 79,796 | 1,143,540 | SH | | DFND | 1 | 1,143,540 | 0 | 0 |
| PFIZER INC | COM | 717081103 | 6,147 | 104,090 | SH | | DFND | 1 | 104,090 | 0 | 0 |
| PHYSICIANS RLTY TR | COM | 71943U104 | 1,770 | 94,000 | SH | | DFND | 1 | 94,000 | 0 | 0 |
| PIMCO GLOBAL STOCKSPLS INCM | COM | 722011103 | 825 | 76,200 | SH | | DFND | 1 | 76,200 | 0 | 0 |
| PINDUODUO INC | SPONSORED ADS | 722304102 | 251 | 4,300 | SH | | DFND | 1 | 4,300 | 0 | 0 |
| RAYTHEON TECHNOLOGIES CORP | COM | 75513E101 | 21,584 | 250,800 | SH | | DFND | 1 | 250,800 | 0 | 0 |
| REDWOOD TR INC | COM | 758075402 | 19,136 | 1,450,800 | SH | | DFND | 1 | 1,450,800 | 0 | 0 |
| REDWOOD TRUST INC | NOTE 4.750% 8/1 | 758075AC9 | 2,018 | 1,978,000 | PRN | | DFND | 1 | 1,978,000 | 0 | 0 |
| REGENERON PHARMACEUTICALS | COM | 75886F107 | 16,445 | 26,040 | SH | | DFND | 1 | 26,040 | 0 | 0 |
| RIVERNORTH FLEXIBLE MUNI INC | COM | 76883Y107 | 385 | 19,395 | SH | | DFND | 1 | 19,395 | 0 | 0 |
| ROYAL CARIBBEAN GROUP | COM | V7780T103 | 8,793 | 114,347 | SH | | DFND | 1 | 114,347 | 0 | 0 |
| SABA CAPITAL INCOME & OPRNT | SHARES | 78518H103 | 2,523 | 558,188 | SH | | DFND | 1 | 558,188 | 0 | 0 |
| SALIENT MIDSTREAM & MLP FD | SH BEN INT | 79471V105 | 641 | 95,038 | SH | | DFND | 1 | 95,038 | 0 | 0 |
| SERVICENOW INC | COM | 81762P102 | 10,850 | 16,715 | SH | | DFND | 1 | 16,715 | 0 | 0 |
| SHOPIFY INC | CL A | 82509L107 | 17,011 | 12,350 | SH | | DFND | 1 | 12,350 | 0 | 0 |
| STARWOOD PPTY TR INC | COM | 85571B105 | 20,611 | 848,200 | SH | | DFND | 1 | 848,200 | 0 | 0 |
| STARWOOD PPTY TR INC | NOTE 4.375% 4/0 | 85571BAH8 | 11,306 | 10,815,000 | PRN | | DFND | 1 | 10,815,000 | 0 | 0 |
| TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADS | 874039100 | 38,331 | 318,600 | SH | | DFND | 1 | 318,600 | 0 | 0 |
| TELADOC HEALTH INC | COM | 87918A105 | 8,636 | 94,050 | SH | | DFND | 1 | 94,050 | 0 | 0 |
| TELADOC HEALTH INC | NOTE 1.250% 6/0 | 87918AAF2 | 643 | 700,000 | PRN | | DFND | 1 | 700,000 | 0 | 0 |
| TENET HEALTHCARE CORP | COM NEW | 88033G407 | 9,345 | 114,400 | SH | | DFND | 1 | 114,400 | 0 | 0 |
| TESLA INC | COM | 88160R101 | 72,832 | 68,919 | SH | | DFND | 1 | 68,919 | 0 | 0 |
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 10,420 | 15,617 | SH | | DFND | 1 | 15,617 | 0 | 0 |
| THORNBURG INCM BUILDER OPP T | COM | 885213108 | 881 | 47,200 | SH | | DFND | 1 | 47,200 | 0 | 0 |
| T-MOBILE US INC | COM | 872590104 | 11,370 | 98,030 | SH | | DFND | 1 | 98,030 | 0 | 0 |
| TORTOISE MIDSTRM ENERGY FD I | COM | 89148B200 | 769 | 25,219 | SH | | DFND | 1 | 25,219 | 0 | 0 |
| TRANSDIGM GROUP INC | COM | 893641100 | 18,156 | 28,534 | SH | | DFND | 1 | 28,534 | 0 | 0 |
| TWO HARBORS INVENTMENT CORPO | NOTE 6.250% 1/1 | 90187BAA9 | 1,799 | 1,799,000 | PRN | | DFND | 1 | 1,799,000 | 0 | 0 |
| VANECK ETF TRUST | PHARMACEUTCL ETF | 92189F692 | 5,372 | 69,800 | SH | | DFND | 1 | 69,800 | 0 | 0 |
| VERACYTE INC | COM | 92337F107 | 7,567 | 183,660 | SH | | DFND | 1 | 183,660 | 0 | 0 |
| VERTEX PHARMACEUTICALS INC | COM | 92532F100 | 23,521 | 107,110 | SH | | DFND | 1 | 107,110 | 0 | 0 |
| VIACOMCBS INC | CL B | 92556H206 | 14,103 | 467,300 | SH | | DFND | 1 | 467,300 | 0 | 0 |
| VIRTUS ALLIANZGI EQUITY & CO | COM | 92841M101 | 901 | 29,900 | SH | | DFND | 1 | 29,900 | 0 | 0 |
| VISA INC | COM CL A | 92826C839 | 5,843 | 26,960 | SH | | DFND | 1 | 26,960 | 0 | 0 |
| WALKER & DUNLOP INC | COM | 93148P102 | 13,689 | 90,730 | SH | | DFND | 1 | 90,730 | 0 | 0 |
| WESTERN ASSET DIVERSIFIED IN | COM SHS BEN INT | 95790K109 | 875 | 47,800 | SH | | DFND | 1 | 47,800 | 0 | 0 |
| WESTERN AST INFL LKD OPP & I | COM | 95766R104 | 866 | 63,800 | SH | | DFND | 1 | 63,800 | 0 | 0 |
| YUM CHINA HLDGS INC | COM | 98850P109 | 368 | 7,500 | SH | | DFND | 1 | 7,500 | 0 | 0 |
| ZOETIS INC | CL A | 98978V103 | 9,195 | 37,681 | SH | | DFND | 1 | 37,681 | 0 | 0 |
