Clough Capital Partners L P 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
2SEVENTY BIO INC	COMMON STOCK	901384107	5,354,593	529,110	SH		DFND	1	529,110	0	0
3M CO	COM	88579Y101	1,501,350	15,000	SH		DFND	1	15,000	0	0
ABBVIE INC	COM	00287Y109	471,555	3,500	SH		DFND	1	3,500	0	0
ABRDN GLOBAL DYNAMIC DIVIDEN	COM	00302M106	352,284	36,927	SH		DFND	1	36,927	0	0
ABRDN INCOME CREDIT STRATEGI	COM	003057106	8,623,168	1,260,697	SH		DFND	1	1,260,697	0	0
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	8,016,562	100,660	SH		DFND	1	100,660	0	0
ACCENTURE PLC IRELAND	SHS CLASS A	G1151C101	6,264,174	20,300	SH		DFND	1	20,300	0	0
AIR PRODS & CHEMS INC	COM	009158106	2,456,146	8,200	SH		DFND	1	8,200	0	0
ALPHABET INC	CAP STK CL C	02079K107	42,362,484	350,190	SH		DFND	1	350,190	0	0
AMAZON COM INC	COM	023135106	22,749,775	174,515	SH		DFND	1	174,515	0	0
AMGEN INC	COM	031162100	3,570,082	16,080	SH		DFND	1	16,080	0	0
AMPHENOL CORP NEW	CL A	032095101	569,165	6,700	SH		DFND	1	6,700	0	0
ANALOG DEVICES INC	COM	032654105	15,428,952	79,200	SH		DFND	1	79,200	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	7,623,157	83,679	SH		DFND	1	83,679	0	0
APPLE INC	COM	037833100	13,744,714	70,860	SH		DFND	1	70,860	0	0
ARCELLX INC	COMMON STOCK	03940C100	3,347,356	105,862	SH		DFND	1	105,862	0	0
ARDELYX INC	COM	039697107	3,630,351	1,070,900	SH		DFND	1	1,070,900	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	4,569,600	51,200	SH		DFND	1	51,200	0	0
AT&T INC	COM	00206R102	1,025,585	64,300	SH		DFND	1	64,300	0	0
AUTOLIV INC	COM	052800109	1,483,948	17,450	SH		DFND	1	17,450	0	0
BANK AMERICA CORP	COM	060505104	846,355	29,500	SH		DFND	1	29,500	0	0
BAXTER INTL INC	COM	071813109	14,040,590	308,178	SH		DFND	1	308,178	0	0
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	337,590	990	SH		DFND	1	990	0	0
BERKSHIRE HATHAWAY INC DEL	CL A	084670108	10,874,010	21	SH		DFND	1	21	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	4,158,040	47,970	SH		DFND	1	47,970	0	0
BLACKROCK CALIF MUN INCOME T	SH BEN INT	09248E102	148,677	12,536	SH		DFND	1	12,536	0	0
BLACKROCK CAP ALLOCATION TER	COM	09260U109	7,556,833	495,530	SH		DFND	1	495,530	0	0
BLACKROCK ESG CAP ALLC TERM	SHS BEN INT	09262F100	853,470	54,500	SH		DFND	1	54,500	0	0
BLACKROCK HEALTH SCIENCES TE	COM SHS	09260E105	4,757,465	289,736	SH		DFND	1	289,736	0	0
BLACKROCK INNOVATION AND GRW	SHS BEN INT	09260Q108	18,603,754	2,369,905	SH		DFND	1	2,369,905	0	0
BLACKROCK SCIENCE & TECHNOLO	SHS BEN INT	09260K101	4,490,193	247,940	SH		DFND	1	247,940	0	0
BLACKSTONE MTG TR INC	COM CL A	09257W100	3,092,428	148,603	SH		DFND	1	148,603	0	0
BLACKSTONE SECD LENDING FD	COMMON STOCK	09261X102	4,883,760	178,500	SH		DFND	1	178,500	0	0
BOEING CO	COM	097023105	24,323,520	115,190	SH		DFND	1	115,190	0	0
BOOKING HOLDINGS INC	COM	09857L108	2,970,363	1,100	SH		DFND	1	1,100	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	3,886,907	71,860	SH		DFND	1	71,860	0	0
BRISTOL-MYERS SQUIBB CO	COM	110122108	2,410,915	37,700	SH		DFND	1	37,700	0	0
BROADCOM INC	COM	11135F101	8,821,763	10,170	SH		DFND	1	10,170	0	0
CARNIVAL CORP	COMMON STOCK	143658300	25,230,317	1,339,900	SH		DFND	1	1,339,900	0	0
CBRE GBL REAL ESTATE INC FD	COM	12504G100	2,669,298	510,382	SH		DFND	1	510,382	0	0
CENTER COAST BRKFLD MLP ENRG	SHS BEN INT	151461209	3,102,936	159,452	SH		DFND	1	159,452	0	0
CHENIERE ENERGY INC	COM NEW	16411R208	5,113,963	33,565	SH		DFND	1	33,565	0	0
CHESAPEAKE ENERGY CORP	COM	165167735	10,585,520	126,500	SH		DFND	1	126,500	0	0
CHEVRON CORP NEW	COM	166764100	1,604,970	10,200	SH		DFND	1	10,200	0	0
CISCO SYS INC	COM	17275R102	3,999,502	77,300	SH		DFND	1	77,300	0	0
CLEARBRIDGE ENERGY MIDSTRM O	COM	18469P209	577,134	19,328	SH		DFND	1	19,328	0	0
CLEARBRIDGE MLP AND MIDSTRM	COM	18469Q207	818,634	25,800	SH		DFND	1	25,800	0	0
COCA COLA CO	COM	191216100	3,869,135	64,250	SH		DFND	1	64,250	0	0
COMCAST CORP NEW	CL A	20030N101	2,152,290	51,800	SH		DFND	1	51,800	0	0
COMERICA INC	COM	200340107	7,146,132	168,700	SH		DFND	1	168,700	0	0
CORNERSTONE STRATEGIC VALUE	COM	21924B302	134,918	16,100	SH		DFND	1	16,100	0	0
CORNERSTONE TOTAL RETURN FD	COM	21924U300	134,400	16,800	SH		DFND	1	16,800	0	0
CRISPR THERAPEUTICS AG	NAMEN AKT	H17182108	3,198,240	56,969	SH		DFND	1	56,969	0	0
CROWN CASTLE INC	COM	22822V101	1,970,023	17,290	SH		DFND	1	17,290	0	0
D R HORTON INC	COM	23331A109	3,322,137	27,300	SH		DFND	1	27,300	0	0
DISNEY WALT CO	COM	254687106	3,597,984	40,300	SH		DFND	1	40,300	0	0
DOW INC	COM	260557103	2,039,858	38,300	SH		DFND	1	38,300	0	0
DRAFTKINGS INC NEW	COM CL A	26142V105	20,886,677	786,100	SH		DFND	1	786,100	0	0
DUKE ENERGY CORP NEW	COM NEW	26441C204	4,307,520	48,000	SH		DFND	1	48,000	0	0
EATON VANCE NEW YORK MUN BD	COM	27827Y109	975,720	103,800	SH		DFND	1	103,800	0	0
EATON VANCE SR INCOME TR	SH BEN INT	27826S103	481,375	88,164	SH		DFND	1	88,164	0	0
ECOFIN SUSTAINABLE AND SOCIA	COM SH BEN INT	27901F109	152,256	12,200	SH		DFND	1	12,200	0	0
ELEVANCE HEALTH INC	COM	036752103	2,221,450	5,000	SH		DFND	1	5,000	0	0
ENCOMPASS HEALTH CORP	COM	29261A100	9,272,140	136,939	SH		DFND	1	136,939	0	0
EXELON CORP	COM	30161N101	5,899,152	144,800	SH		DFND	1	144,800	0	0
EXXON MOBIL CORP	COM	30231G102	14,704,511	137,105	SH		DFND	1	137,105	0	0
FIRST TR DYNAMIC EUROPE EQUI	COM SHS	33740D107	1,359,972	103,775	SH		DFND	1	103,775	0	0
FIRST TR SR FLTG RATE INCOME	COM	33733U108	655,380	66,200	SH		DFND	1	66,200	0	0
FREEPORT-MCMORAN INC	CL B	35671D857	5,036,000	125,900	SH		DFND	1	125,900	0	0
GENERAL MLS INC	COM	370334104	3,489,850	45,500	SH		DFND	1	45,500	0	0
GILEAD SCIENCES INC	COM	375558103	593,439	7,700	SH		DFND	1	7,700	0	0
GOLDMAN SACHS MLP ENERGY REN	COM	38148G206	3,763,121	239,842	SH		DFND	1	239,842	0	0
GOLUB CAP BDC INC	COM	38173M102	672,840	49,840	SH		DFND	1	49,840	0	0
HALOZYME THERAPEUTICS INC	COM	40637H109	4,277,902	118,600	SH		DFND	1	118,600	0	0
HANCOCK JOHN INVT TR	TAX ADV GLB SH	41013P749	983,118	209,620	SH		DFND	1	209,620	0	0
HCA HEALTHCARE INC	COM	40412C101	10,731,053	35,360	SH		DFND	1	35,360	0	0
HDFC BANK LTD	SPONSORED ADS	40415F101	17,424,652	249,995	SH		DFND	1	249,995	0	0
HERTZ GLOBAL HLDGS INC	COM NEW	42806J700	1,686,547	91,710	SH		DFND	1	91,710	0	0
HERTZ GLOBAL HLDGS INC	W EXP 06/30/205	42806J148	3,707,116	367,405	SH		DFND	1	367,405	0	0
HERZFELD CARIBBEAN BASIN FD	COM	42804T106	238,142	60,289	SH		DFND	1	60,289	0	0
HOLOGIC INC	COM	436440101	7,845,993	96,900	SH		DFND	1	96,900	0	0
HOME DEPOT INC	COM	437076102	8,146,534	26,225	SH		DFND	1	26,225	0	0
ICICI BANK LIMITED	ADR	45104G104	11,300,891	489,640	SH		DFND	1	489,640	0	0
ILLINOIS TOOL WKS INC	COM	452308109	550,352	2,200	SH		DFND	1	2,200	0	0
ILLUMINA INC	COM	452327109	10,291,326	54,890	SH		DFND	1	54,890	0	0
INTERNATIONAL PAPER CO	COM	460146103	725,268	22,800	SH		DFND	1	22,800	0	0
INVESCO SR INCOME TR	COM	46131H107	344,190	89,400	SH		DFND	1	89,400	0	0
ISHARES TR	MSCI CHINA ETF	46429B671	3,306,286	73,900	SH		DFND	1	73,900	0	0
JAZZ PHARMACEUTICALS PLC	SHS USD	G50871105	3,486,036	28,120	SH		DFND	1	28,120	0	0
JOHN HANCOCK HEDGED EQUITY &	COM	47804L102	644,644	59,800	SH		DFND	1	59,800	0	0
JOHNSON & JOHNSON	COM	478160104	19,211,079	116,065	SH		DFND	1	116,065	0	0
JOHNSON CTLS INTL PLC	SHS	G51502105	558,748	8,200	SH		DFND	1	8,200	0	0
JPMORGAN CHASE & CO	COM	46625H100	9,337,248	64,200	SH		DFND	1	64,200	0	0
KAYNE ANDERSON NEXTGEN ENRGY	COM	48661E108	461,741	65,034	SH		DFND	1	65,034	0	0
KEYCORP	COM	493267108	5,641,944	610,600	SH		DFND	1	610,600	0	0
KINDER MORGAN INC DEL	COM	49456B101	13,192,449	766,112	SH		DFND	1	766,112	0	0
KKR INCOME OPPORTUNITIES FD	COM	48249T106	8,849,316	762,215	SH		DFND	1	762,215	0	0
KROGER CO	COM	501044101	2,279,500	48,500	SH		DFND	1	48,500	0	0
LAM RESEARCH CORP	COM	512807108	16,778,646	26,100	SH		DFND	1	26,100	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	2,837,133	41,100	SH		DFND	1	41,100	0	0
LINDE PLC	SHS	G54950103	5,297,012	13,900	SH		DFND	1	13,900	0	0
LOCKHEED MARTIN CORP	COM	539830109	460,380	1,000	SH		DFND	1	1,000	0	0
M & T BK CORP	COM	55261F104	7,190,456	58,100	SH		DFND	1	58,100	0	0
MAINSTAY CBRE GLOBAL INFRA	COM	56064Q107	5,450,655	397,858	SH		DFND	1	397,858	0	0
MARRIOTT INTL INC NEW	CL A	571903202	1,598,103	8,700	SH		DFND	1	8,700	0	0
MARVELL TECHNOLOGY INC	COM	573874104	9,194,164	153,800	SH		DFND	1	153,800	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	9,458,865	24,050	SH		DFND	1	24,050	0	0
MCDONALDS CORP	COM	580135101	2,536,485	8,500	SH		DFND	1	8,500	0	0
MEDTRONIC PLC	SHS	G5960L103	2,810,390	31,900	SH		DFND	1	31,900	0	0
MELCO RESORTS AND ENTMNT LTD	ADR	585464100	7,454,205	610,500	SH		DFND	1	610,500	0	0
MERCK & CO INC	COM	58933Y105	12,535,970	108,640	SH		DFND	1	108,640	0	0
MERITAGE HOMES CORP	COM	59001A102	3,129,940	22,000	SH		DFND	1	22,000	0	0
METLIFE INC	COM	59156R108	4,912,457	86,900	SH		DFND	1	86,900	0	0
MICROSOFT CORP	COM	594918104	38,389,415	112,731	SH		DFND	1	112,731	0	0
MORGAN STANLEY	COM NEW	617446448	1,942,850	22,750	SH		DFND	1	22,750	0	0
MORGAN STANLEY EMKT DBT FD I	COM	61744H105	67,620	10,500	SH		DFND	1	10,500	0	0
NEUBERGER BERMAN HIGH YIELD	COM	64128C106	2,618,841	349,645	SH		DFND	1	349,645	0	0
NEUBERGER BERMAN NEXT GENERA	COMMON STOCK	64133Q108	1,969,255	180,500	SH		DFND	1	180,500	0	0
NEUBERGER BERMAN REAL ESTATE	COM	64190A103	259,513	85,366	SH		DFND	1	85,366	0	0
NEWELL BRANDS INC	COM	651229106	436,740	50,200	SH		DFND	1	50,200	0	0
NORTHROP GRUMMAN CORP	COM	666807102	19,316,804	42,380	SH		DFND	1	42,380	0	0
NORWEGIAN CRUISE LINE HLDG L	SHS	G66721104	2,335,050	107,260	SH		DFND	1	107,260	0	0
NUVEEN CORE PLUS IMPACT FUND	COM BEN INT	67080D103	733,792	73,600	SH		DFND	1	73,600	0	0
NUVEEN MULTI ASSET INCOME FU	COM	670750108	2,825,218	242,300	SH		DFND	1	242,300	0	0
PALO ALTO NETWORKS INC	COM	697435105	9,672,331	37,855	SH		DFND	1	37,855	0	0
PEPSICO INC	COM	713448108	1,259,496	6,800	SH		DFND	1	6,800	0	0
PFIZER INC	COM	717081103	2,496,808	68,070	SH		DFND	1	68,070	0	0
PIMCO ENERGY & TACTICAL CR O	COM SHS BEN INT	69346N107	377,736	23,968	SH		DFND	1	23,968	0	0
PIONEER FLOATING RATE FUND I	COM	72369J102	1,690,135	194,716	SH		DFND	1	194,716	0	0
PRINCIPAL REAL ESTATE INCOME	SHS BEN INT	74255X104	410,838	43,429	SH		DFND	1	43,429	0	0
PROCTER AND GAMBLE CO	COM	742718109	9,938,970	65,500	SH		DFND	1	65,500	0	0
PROLOGIS INC.	COM	74340W103	1,287,615	10,500	SH		DFND	1	10,500	0	0
PRUDENTIAL FINL INC	COM	744320102	352,880	4,000	SH		DFND	1	4,000	0	0
PULTE GROUP INC	COM	745867101	3,456,760	44,500	SH		DFND	1	44,500	0	0
PUTNAM MANAGED MUN INCOME TR	COM	746823103	150,295	24,679	SH		DFND	1	24,679	0	0
PUTNAM MASTER INTER INCOME T	SH BEN INT	746909100	271,444	85,900	SH		DFND	1	85,900	0	0
PUTNAM MUN OPPORTUNITIES TR	SH BEN INT	746922103	463,534	45,400	SH		DFND	1	45,400	0	0
RAYTHEON TECHNOLOGIES CORP	COM	75513E101	26,057,360	266,000	SH		DFND	1	266,000	0	0
REDWOOD TRUST INC	NOTE 4.750% 8/1	758075AC9	1,697,875	1,700,000	PRN		DFND	1	1,700,000	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	5,608,205	7,805	SH		DFND	1	7,805	0	0
RIVERNORTH DOUBLELINE STRATE	COM	76882G107	2,144,693	251,135	SH		DFND	1	251,135	0	0
RIVERNORTH OPPORTUNITIES FD	COM	76881Y109	188,794	16,503	SH		DFND	1	16,503	0	0
ROIVANT SCIENCES LTD	SHS	G76279101	5,115,600	507,500	SH		DFND	1	507,500	0	0
ROYAL CARIBBEAN GROUP	COM	V7780T103	21,126,340	203,647	SH		DFND	1	203,647	0	0
SCHLUMBERGER LTD	COM STK	806857108	4,009,666	81,630	SH		DFND	1	81,630	0	0
SCHWAB CHARLES CORP	COM	808513105	7,408,076	130,700	SH		DFND	1	130,700	0	0
SELECT MED HLDGS CORP	COM	81619Q105	9,510,210	298,500	SH		DFND	1	298,500	0	0
SERVICENOW INC	COM	81762P102	14,304,946	25,455	SH		DFND	1	25,455	0	0
SHERWIN WILLIAMS CO	COM	824348106	2,469,336	9,300	SH		DFND	1	9,300	0	0
SIMON PPTY GROUP INC NEW	COM	828806109	1,893,872	16,400	SH		DFND	1	16,400	0	0
SOUTHWESTERN ENERGY CO	COM	845467109	10,186,950	1,695,000	SH		DFND	1	1,695,000	0	0
STARBUCKS CORP	COM	855244109	1,892,046	19,100	SH		DFND	1	19,100	0	0
STARWOOD PPTY TR INC	COM	85571B105	2,869,532	147,914	SH		DFND	1	147,914	0	0
SURGERY PARTNERS INC	COM	86881A100	9,079,117	201,803	SH		DFND	1	201,803	0	0
TENET HEALTHCARE CORP	COM NEW	88033G407	2,627,760	32,290	SH		DFND	1	32,290	0	0
TESLA INC	COM	88160R101	2,766,909	10,570	SH		DFND	1	10,570	0	0
TEXAS INSTRS INC	COM	882508104	1,242,138	6,900	SH		DFND	1	6,900	0	0
THE CIGNA GROUP	COM	125523100	533,140	1,900	SH		DFND	1	1,900	0	0
T-MOBILE US INC	COM	872590104	1,259,823	9,070	SH		DFND	1	9,070	0	0
TRANSDIGM GROUP INC	COM	893641100	20,646,385	23,090	SH		DFND	1	23,090	0	0
TRANSOCEAN LTD	REG SHS	H8817H100	10,412,955	1,485,443	SH		DFND	1	1,485,443	0	0
TRIP COM GROUP LTD	ADS	89677Q107	4,077,500	116,500	SH		DFND	1	116,500	0	0
UNITED PARCEL SERVICE INC	CL B	911312106	483,975	2,700	SH		DFND	1	2,700	0	0
UNITED STS NAT GAS FD LP	UNIT PAR	912318300	1,154,033	155,530	SH		DFND	1	155,530	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	2,809,821	5,846	SH		DFND	1	5,846	0	0
VERACYTE INC	COM	92337F107	7,036,342	276,260	SH		DFND	1	276,260	0	0
VERIZON COMMUNICATIONS INC	COM	92343V104	502,065	13,500	SH		DFND	1	13,500	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	9,164,088	26,041	SH		DFND	1	26,041	0	0
VICI PPTYS INC	COM	925652109	634,886	20,200	SH		DFND	1	20,200	0	0
VIRTUS STONE HBR EMG MKTS TO	COM	86164W100	409,004	79,111	SH		DFND	1	79,111	0	0
VIRTUS TOTAL RETURN FD INC	COM	92835W107	7,555,932	1,242,752	SH		DFND	1	1,242,752	0	0
VISA INC	COM CL A	92826C839	5,389,609	22,695	SH		DFND	1	22,695	0	0
VORNADO RLTY TR	SH BEN INT	929042109	2,083,923	114,880	SH		DFND	1	114,880	0	0
VOYA GLBL EQTY DIV & PREM OP	COM	92912T100	100,230	19,500	SH		DFND	1	19,500	0	0
WYNN RESORTS LTD	COM	983134107	12,326,799	116,720	SH		DFND	1	116,720	0	0
ZIMMER BIOMET HOLDINGS INC	COM	98956P102	9,532,432	65,470	SH		DFND	1	65,470	0	0