Immunic (IMUX) 8-K Immunic Therapeutics and Vital Therapies Complete Transaction

Exhibit 16.1

April 15, 2019

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Commissioners:

We have read the statements made by Vital Therapies, Inc. (copy attached), which we understand will be filed with the Securities and Exchange Commission, pursuant to Item 4.01 of Form8-K of Vital Therapies, Inc. dated April 12, 2019. We agree with the statements concerning our Firm contained therein.

Very truly yours,

/s/ PricewaterhouseCoopers LLP

San Diego, California