Omeros (OMER) 10-Q 2013 Q2 Quarterly report

				EXHIBIT 12.1
Omeros Corporation
Computation of Deficiency in the Coverage of Fixed Charges by Earnings Before Fixed Charges
	For the
	six months
	ended
	June 30,			Year Ended December 31,
	2013			2012			2011			2010			2009			2008
	(in thousands, except share data)
Earnings before fixed charges:
Loss from continuing operations before income taxes	$	(24,081	)	$	(38,444	)	$	(28,546	)	$	(29,251	)	$	(21,089	)	$	(23,827	)
Add fixed charges	2,757			2,305			2,144			2,104			2,596			834
Add amortization of capitalized interest	0			0			0			0			0			0
Add distributed income of equity investees	0			0			0			0			0			0
Subtract capitalized interest	0			0			0			0			0			0
Loss before fixed charges	$	(21,324	)	$	(36,139	)	$	(26,402	)	$	(27,147	)	$	(18,493	)	$	(22,993	)
Fixed Charges:
Interest expense	$	932		$	1,355		$	1,532		$	1,328		$	1,948		$	280
Amortization of debt expense and loss from extinguishment of debt	244			374			352			503			254			55
Estimate of interest expense within rental expense	1,581			576			260			273			394			499
Preference security dividend requirements of consolidated subsidiaries	0			0			0			0			0			0
Total fixed charges	$	2,757		$	2,305		$	2,144		$	2,104		$	2,596		$	834
Deficiency of earnings available to cover fixed charges	$	(24,081	)	$	(38,444	)	$	(28,546	)	$	(29,251	)	$	(21,089	)	$	(23,827	)