The following table provides details regarding the sources of our revenue for the periods presented.
| | | | | | | | | | | | | | | | | |
| | Three Months Ended | | | | Six Months Ended | | | |
| | June 30, | | | | June 30, | | | |
| | 2022 | | 2021 | | % | | 2022 | | 2021 | | % | |
(in thousands, except percentages) | | | | | | | | | | | | | | | | | |
Cell therapy | | $ | 7,688 | | $ | 4,766 | | 61% | | $ | 15,104 | | $ | 9,494 | | 59% | |
Drug discovery | | | 1,916 | | | 1,838 | | 4% | | | 4,083 | | | 3,601 | | 13% | |
Program-related | | | 4 | | | 504 | | NM | | | 2,008 | | | 508 | | 295% | |
Total revenue | | $ | 9,608 | | $ | 7,108 | | 35% | | $ | 21,195 | | $ | 13,603 | | 56% | |
Second Quarter 2022 Financial Results
Total revenue for the second quarter of 2022 was $9.6 million, compared to $7.1 million in the second quarter of 2021, representing growth of 35%.
Core business revenue was $9.6 million, including 61% revenue growth from cell therapy customers and 4% from drug discovery customers, compared to core business revenue of $6.6 million in the same period last year.
We did not have any material SPL Program-related revenue in the second quarter of 2022, as compared to $0.5 million in the second quarter of 2021.
Gross profit for the second quarter of 2022 was $8.5 million (88% gross margin), compared to $6.3 million (89% gross margin) in the same period of the prior year.
Operating expenses for the second quarter of 2022 were $17.2 million, compared to operating expenses of $10.7 million in the second quarter of 2021. The overall increase in operating expenses was primarily driven by increased staff in field sales and science, manufacturing, and lab teams to support our customers’ and partners’ growth. The increase also included additional public company-related, stock-based compensation, and marketing expenses compared with the same period a year ago.
Second quarter 2022 net loss was $8.3 million compared to net loss of $4.4 million for the same period in 2021. EBITDA, a non-GAAP measure, was a loss of $8.2 million for the second quarter of 2022, compared to a loss of $4.1 million for the second quarter of the prior year. Stock-based compensation expense was $3.0 million for the second quarter versus $1.9 million for the same period in the prior year.
Total cash, cash equivalents and short-term investments were $240.9 million as of June 30, 2022.
First Half 2022 Financial Results
Total revenue for the first half of 2022 was $21.2 million, compared to $13.6 million in the first half of 2021, representing growth of 56%. Overall sales to the cell therapy (up 59%) and the drug discovery (up 13%) markets were sources of strength in the first half.
The Company recognized $2.0 million of program-related revenue in the first half of 2022, as compared to $0.5 million in program-related revenue in the first half of 2021.
Gross profit for the first half of 2022 was $19.0 million (90% gross margin), compared to $12.1 million (89% gross margin) in the same period of the prior year.