August 16, 2017
Via EDGAR
U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549-3720
| Attention: | Amanda Ravitz |
Tim Buchmiller
| Re: | Pacific Biosciences of California, Inc. |
Registration Statement on FormS-3
Filed August 2, 2017
FileNo. 333-219642
Acceleration Request
Requested Date: August 18, 2017
Requested Time: 4:00 PM Eastern Time
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Pacific Biosciences of California, Inc. (the “Company”) hereby requests that the above-referenced Registration Statement onForm S-3 (FileNo. 333-219642) (the “Registration Statement”) be declared effective at the “Requested Date” and “Requested Time” set forth above or as soon thereafter as practicable, or at such later time as the Company may request by telephone to the staff (the “Staff”) of the Securities and Exchange Commission (the “Commission”). The Company hereby authorizes Andrew D. Hoffman of Wilson Sonsini Goodrich & Rosati, Professional Corporation, counsel for the Company, to make such request on the Company’s behalf.
The Company requests that it be notified of the effectiveness of the Registration Statement by telephone to Andrew D. Hoffman of Wilson Sonsini Goodrich & Rosati, Professional Corporation, at(650) 849-3240. Please also provide a copy of the Commission’s order declaring the Registration Statement effective to Andrew D. Hoffman via facsimile at(650) 493-6811.
Please direct any questions or comments regarding this acceleration request to Andrew D. Hoffman at(650) 849-3240.
*****
1305 O’Brien Drive, Menlo Park, CA 94025
| Sincerely, | ||
| PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | ||
| By: | /s/ Susan K. Barnes | |
| Susan K. Barnes | ||
| Executive Vice President, Chief Financial Officer and Principal Accounting Officer | ||
| cc: | Donna M. Petkanics, Esq. |
Andrew D. Hoffman, Esq.
Wilson Sonsini Goodrich & Rosati, Professional Corporation
Page 2