Tekla Capital Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
Abbott Laboratories	Common	002824100	58,301	1,378,600	SH		SOLE		1,378,600	0	0
AbbVie Inc.	Common	00287Y109	10	156	SH		SOLE		156	0	0
Acadia Healthcare Company. Inc.	Common	00404A109	1,744	35,200	SH		SOLE		35,200	0	0
ACADIA Pharmaceuticals Inc.	Common	004225108	3,556	111,800	SH		SOLE		111,800	0	0
Accelerate Diagnostics, Inc.	Common	00430H102	3,271	120,000	SH		SOLE		120,000	0	0
Adaptimmune Theraputics plc	Sponsored ADR	00653A107	3,993	566,368	SH		SOLE		566,368	0	0
Aegerion Pharmaceuticals, Inc.	Note 2.00% 8/15/19	00767EAB8	8,572	13,000,000	PRN		SOLE		13,000,000	0	0
Affimed NV	Common	N01045108	818	294,213	SH		SOLE		294,213	0	0
Agilent Technologies, Inc.	Common	00846U101	21,659	459,950	SH		SOLE		459,950	0	0
Akorn, Inc.	Common	009728106	3,959	145,235	SH		SOLE		145,235	0	0
Alexion Pharmaceuticals, Inc.	Common	015351109	93,621	764,005	SH		SOLE		764,005	0	0
Alkermes plc	Shares	G01767105	27,369	581,944	SH		SOLE		581,944	0	0
Allergan plc	Common	G0177J108	99,974	434,086	SH		SOLE		434,086	0	0
Allergan plc	Preferred Convertible	G0177J116	4,108	5,000	SH		SOLE		5,000	0	0
Alliqua BioMedical, Inc.	Common	019621200	1,287	1,650,000	SH		SOLE		1,650,000	0	0
Allscripts Healthcare Solutions, Inc.	Common	01988P108	2,286	173,600	SH		SOLE		173,600	0	0
Alnylam Pharmaceuticals, Inc.	Common	02043Q107	16,538	243,995	SH		SOLE		243,995	0	0
AmerisourceBergen Corporation	Common	03073E105	26,713	330,687	SH		SOLE		330,687	0	0
Amgen Inc.	Common	031162100	53,653	321,640	SH		SOLE		321,640	0	0
Amicus Therapeutics, Inc.	Common	03152W109	1,909	258,000	SH		SOLE		258,000	0	0
ARCA biopharma, Inc.	Common	00211Y407	2,344	811,227	SH		SOLE		811,227	0	0
Ardelyx, Inc.	Common	039697107	9,157	707,636	SH		SOLE		707,636	0	0
ARIAD Pharmaceuticals, Inc.	Common	04033A100	6,872	502,000	SH		SOLE		502,000	0	0
AstraZeneca PLC	Sponsored ADR	046353108	15,240	463,800	SH		SOLE		463,800	0	0
Auris Medical Holding AG	Common	H03579101	1,340	774,504	SH		SOLE		774,504	0	0
Becton Dickinson and Company	Common	075887109	11,337	63,078	SH		SOLE		63,078	0	0
BeiGene Ltd.	Sponsored ADR	07725L102	3,596	116,707	SH		SOLE		116,707	0	0
Bellicum Pharmaceuticals, Inc.	Common	079481107	1,194	60,000	SH		SOLE		60,000	0	0
Biogen Inc.	Common	09062X103	150,891	482,033	SH		SOLE		482,033	0	0
BioMarin Pharmaceutical Inc.	Common	09061G101	65,703	710,145	SH		SOLE		710,145	0	0
bluebird bio, Inc.	Common	09609G100	3,345	49,345	SH		SOLE		49,345	0	0
Cardinal Health, Inc.	Common	14149Y108	11,849	152,500	SH		SOLE		152,500	0	0
Celgene Corporation	Common	151020104	155,132	1,484,089	SH		SOLE		1,484,089	0	0
Celldex Therapeutics, Inc.	Common	15117B103	427	105,800	SH		SOLE		105,800	0	0
Cellectis S.A.	Sponsored ADR	15117K103	7,471	310,250	SH		SOLE		310,250	0	0
Centene Corporation	Common	15135B101	17,175	256,500	SH		SOLE		256,500	0	0
Cepheid, Inc.	Common	15670R107	17,577	333,590	SH		SOLE		333,590	0	0
Charles River Laboratories International, Inc.	Common	159864107	9,584	115,000	SH		SOLE		115,000	0	0
Chimerix, Inc.	Common	16934W106	1,711	308,892	SH		SOLE		308,892	0	0
Cidara Therapeutics, Inc.	Common	171757107	1,517	132,472	SH		SOLE		132,472	0	0
Cigna Corporation	Common	125509109	11,260	86,400	SH		SOLE		86,400	0	0
Community Health Systems, Inc.	Common	203668108	3,514	304,472	SH		SOLE		304,472	0	0
CVS Caremark Corporation	Common	126650100	36,654	411,891	SH		SOLE		411,891	0	0
CytomX Therapeutics, Inc.	Common	23284F105	11,855	756,090	SH		SOLE		756,090	0	0
DaVita, Inc.	Common	23918K108	10,644	161,100	SH		SOLE		161,100	0	0
DBV Technologies	Sponsored ADR	23306J101	2,383	65,600	SH		SOLE		65,600	0	0
Depomed, Inc.	Common	249908104	4,998	200,000	SH		SOLE		200,000	0	0
Dermira, Inc.	Common	24983L104	2,794	82,600	SH		SOLE		82,600	0	0
Diplomat Pharmacy, Inc.	Common	25456K101	2,441	87,163	SH		SOLE		87,163	0	0
Dynavax Technologies Corporation	Common	268158201	3,620	345,050	SH		SOLE		345,050	0	0
Egalet Corporation	Note 5.50% 4/1/20	28226BAB0	5,963	7,000,000	PRN		SOLE		7,000,000	0	0
Eli Lilly & Company	Common	532457108	57,287	713,767	SH		SOLE		713,767	0	0
Endo International plc	Shares	G30401106	18,428	914,548	SH		SOLE		914,548	0	0
Endologix, Inc.	Common	29266S106	9,901	773,500	SH		SOLE		773,500	0	0
Epizyme, Inc.	Common	29428V104	3,936	400,000	SH		SOLE		400,000	0	0
Esperion Therapeutics, Inc.	Common	29664W105	1,424	102,800	SH		SOLE		102,800	0	0
Exelixis, Inc.	Common	30161Q104	7,056	551,647	SH		SOLE		551,647	0	0
Flamel Technologies SA	Sponsored ADR	338488109	7,741	624,288	SH		SOLE		624,288	0	0
Flex Pharma, Inc.	Common	33938A105	1,910	162,124	SH		SOLE		162,124	0	0
Foamix Pharmaceuticals, Ltd.	Shares	M46135105	8,946	966,065	SH		SOLE		966,065	0	0
Forward Pharma A/S	Sponsored ADR	34986J105	2,867	136,547	SH		SOLE		136,547	0	0
Galapagos NV	Sponsored ADR	36315X101	9,553	147,738	SH		SOLE		147,738	0	0
GenMark Diagnostics, Inc.	Common	372309104	1,102	93,349	SH		SOLE		93,349	0	0
Gilead Sciences, Inc.	Common	375558103	210,470	2,660,131	SH		SOLE		2,660,131	0	0
GlaxoSmithKline plc	Sponsored ADR	37733W105	15,484	359,000	SH		SOLE		359,000	0	0
Global Blood Therapeutics, Inc.	Common	37890U108	2,881	125,000	SH		SOLE		125,000	0	0
Grifols SA	Sponsored ADR	398438408	2,651	166,000	SH		SOLE		166,000	0	0
Halozyme Therapeutics, Inc.	Common	40637H109	2,416	200,000	SH		SOLE		200,000	0	0
HCA Holdings, Inc.	Common	40412C101	7,237	95,684	SH		SOLE		95,684	0	0
Horizon Pharma plc	Shares	G4617B105	13,596	749,900	SH		SOLE		749,900	0	0
Humana, Inc.	Common	444859102	29,151	164,800	SH		SOLE		164,800	0	0
ICON plc	Shares	G4705A100	5,571	72,000	SH		SOLE		72,000	0	0
IDEXX Laboratories, Inc.	Common	45168D104	14,920	132,352	SH		SOLE		132,352	0	0
Illumina, Inc.	Common	452327109	44,790	246,560	SH		SOLE		246,560	0	0
Immunomedics, Inc.	Note 4.75% 2/15/20	452907AK4	3,378	4,000,000	PRN		SOLE		4,000,000	0	0
Impax Laboratories, Inc.	Common	45256B101	2,947	124,335	SH		SOLE		124,335	0	0
Incyte Corporation	Common	45337C102	83,019	880,461	SH		SOLE		880,461	0	0
Inotek Pharmaceuticals Corporation	Common	45780V102	1,714	180,762	SH		SOLE		180,762	0	0
Intellia Therapeutics, Inc.	Common	45826J105	1,223	71,842	SH		SOLE		71,842	0	0
iShares Nasdaq Biotechnology ETF	ETF	464287556	16,693	57,670	SH		SOLE		57,670	0	0
Jazz Pharmaceuticals plc	Shares	G50871105	40,260	331,411	SH		SOLE		331,411	0	0
Johnson & Johnson	Common	478160104	39,847	337,312	SH		SOLE		337,312	0	0
Juno Therapeutics, Inc.	Common	48205A109	5,462	182,000	SH		SOLE		182,000	0	0
Karyopharm Therapeutics, Inc.	Common	48576U106	4,868	500,324	SH		SOLE		500,324	0	0
LTC Properties, Inc.	Common	502175102	5,522	106,212	SH		SOLE		106,212	0	0
Mallinckrodt plc	Shares	G5785G107	4,319	61,900	SH		SOLE		61,900	0	0
McKesson Corporation	Common	58155Q103	2,501	15,000	SH		SOLE		15,000	0	0
Medical Properties Trust, Inc.	Common	58463J304	12,395	839,217	SH		SOLE		839,217	0	0
The Medicines Company	Common	584688105	21,302	564,438	SH		SOLE		564,438	0	0
Medtronic plc	Shares	G5960L103	53,830	623,030	SH		SOLE		623,030	0	0
Merck & Co., Inc.	Common	58933Y105	77,788	1,246,397	SH		SOLE		1,246,397	0	0
Merrimack Pharmaceuticals, Inc.	Note 4.50% 7/15/20	590328AA8	1,879	1,485,000	PRN		SOLE		1,485,000	0	0
Merrimack Pharmaceuticals, Inc.	Common	590328100	1,816	286,000	SH		SOLE		286,000	0	0
Merus B.V.	Common	N5749R100	4,355	260,000	SH		SOLE		260,000	0	0
Molina Healthcare, Inc.	Common	60855R100	23,476	402,541	SH		SOLE		402,541	0	0
Momenta Pharmaceuticals, Inc.	Common	60877T100	1,797	153,700	SH		SOLE		153,700	0	0
Mylan NV	Shares	N59465109	43,287	1,135,552	SH		SOLE		1,135,552	0	0
Natera, Inc.	Common	632307104	9,803	882,358	SH		SOLE		882,358	0	0
Neurocrine Biosciences, Inc.	Common	64125C109	33,251	656,622	SH		SOLE		656,622	0	0
Nevro Corp.	Common	64157F103	2,610	25,000	SH		SOLE		25,000	0	0
New Senior Investment Group Inc.	Common	648691103	4,974	430,997	SH		SOLE		430,997	0	0
Novartis AG	Sponsored ADR	66987V109	19,645	248,800	SH		SOLE		248,800	0	0
Novavax, Inc.	Common	670002104	1,188	571,000	SH		SOLE		571,000	0	0
Omega Healthcare Investors, Inc.	Common	681936100	14,645	413,116	SH		SOLE		413,116	0	0
Paratek Pharmaceuticals, Inc.	Common	699374302	9,921	762,581	SH		SOLE		762,581	0	0
Perrigo Company plc	Shares	G97822103	3,444	37,300	SH		SOLE		37,300	0	0
Pfizer Inc.	Common	717081103	38,838	1,146,689	SH		SOLE		1,146,689	0	0
Physicians Realty Trust	Common	71943U104	11,431	530,672	SH		SOLE		530,672	0	0
Pieris Pharmaceuticals, Inc.	Common	720795103	7,587	4,145,958	SH		SOLE		4,145,958	0	0
PRA Health Sciences, Inc.	Common	69354M108	5,764	102,000	SH		SOLE		102,000	0	0
Puma Biotechnology, Inc.	Common	74587V107	17,446	260,200	SH		SOLE		260,200	0	0
Quorum Health Corporation	Common	74909E106	477	76,118	SH		SOLE		76,118	0	0
Regeneron Pharmaceuticals, Inc.	Common	75886F107	62,018	154,266	SH		SOLE		154,266	0	0
Retrophin, Inc.	Common	761299106	7,384	329,949	SH		SOLE		329,949	0	0
Revance Therapeutics, Inc.	Common	761330109	1,216	75,000	SH		SOLE		75,000	0	0
The RMR Group Inc.	Class A	74967R106	282	7,441	SH		SOLE		7,441	0	0
Sabra Health Care REIT, Inc.	Common	78573L106	11,487	456,190	SH		SOLE		456,190	0	0
Sage Therapeutics, Inc.	Common	78667J108	6,760	146,800	SH		SOLE		146,800	0	0
Sanofi	Sponsored ADR	80105N105	11,648	305,000	SH		SOLE		305,000	0	0
Sarepta Therapeutics, Inc.	Common	803607100	13,148	214,100	SH		SOLE		214,100	0	0
Senior Housing Properties Trust	Shares	81721M109	13,059	575,054	SH		SOLE		575,054	0	0
Shire plc	Sponsored ADR	82481R106	44,862	231,413	SH		SOLE		231,413	0	0
Supernus Pharmaceuticals, Inc.	Note 7.50% 5/1/19	868459AB4	9,334	2,000,000	PRN		SOLE		2,000,000	0	0
Tenet Healthcare Corporation	Common	88033G407	3,728	164,500	SH		SOLE		164,500	0	0
Tetraphase Pharmaceuticals Inc.	Common	88165N105	737	192,322	SH		SOLE		192,322	0	0
Teva Pharmaceutical Industries Limited	Sponsored ADR	881624209	36,300	788,958	SH		SOLE		788,958	0	0
TherapeuticsMD, Inc.	Common	88338N107	2,091	307,000	SH		SOLE		307,000	0	0
Thermo Fisher Scientific Inc.	Common	883556102	13,742	86,395	SH		SOLE		86,395	0	0
Ultragenyx Pharmaceutical Inc.	Common	90400D108	6,271	88,400	SH		SOLE		88,400	0	0
UniQure NV	Shares	N90064101	1,844	241,021	SH		SOLE		241,021	0	0
United Therapeutics Corporation	Common	91307C102	10,993	93,100	SH		SOLE		93,100	0	0
Unitedhealth Group, Inc.	Common	91324P102	46,354	331,100	SH		SOLE		331,100	0	0
Universal Health Services, Inc.	Class B	913903100	16,595	134,680	SH		SOLE		134,680	0	0
Valeant Pharmaceuticals International, Inc.	Common	91911K102	4,714	192,000	SH		SOLE		192,000	0	0
Ventas, Inc.	Common	92276F100	10,770	152,491	SH		SOLE		152,491	0	0
Vertex Pharmaceuticals Incorporated	Common	92532F100	90,132	1,033,503	SH		SOLE		1,033,503	0	0
Vitae Pharmaceuticals, Inc.	Common	92847N103	5,230	250,000	SH		SOLE		250,000	0	0
Welltower, Inc.	Preferred Convertible	95040Q203	13,310	200,000	SH		SOLE		200,000	0	0
Xencor, Inc.	Common	98401F105	490	20,000	SH		SOLE		20,000	0	0
Xenon Pharmaceuticals Inc.	Common	98420N105	5,670	700,000	SH		SOLE		700,000	0	0
Zafgen, Inc.	Common	98885E103	44	13,307	SH		SOLE		13,307	0	0
Zimmer Biomet Holdings, Inc.	Common	98956P102	13,301	102,300	SH		SOLE		102,300	0	0