Tekla Capital Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
Abbott Laboratories	Common	002824100	45,577	798,619	SH		SOLE		798,619	0	0
AbbVie Inc.	Common	00287Y109	33,492	346,313	SH		SOLE		346,313	0	0
AC Immune SA	Shares	H00263105	2,199	171,813	SH		SOLE		171,813	0	0
Acadia Healthcare Company, Inc.	Common	00404A109	8,888	272,400	SH		SOLE		272,400	0	0
ACADIA Pharmaceuticals Inc.	Common	004225108	7,404	245,885	SH		SOLE		245,885	0	0
Acceleron Pharma Inc.	Common	00434H108	12,027	283,383	SH		SOLE		283,383	0	0
Achillion Pharmaceuticals, Inc.	Common	00448Q201	1,774	616,000	SH		SOLE		616,000	0	0
Adaptimmune Therapeutics plc	Sponsored ADR	00653A107	6,248	935,368	SH		SOLE		935,368	0	0
Adverum Biotechnologies, Inc.	Common	00773U108	2,604	743,974	SH		SOLE		743,974	0	0
Aegerion Pharmaceuticals, Inc.	Note 2.00% 8/15/19	00767EAB8	10,335	13,000,000	PRN		SOLE		13,000,000	0	0
Aetna Inc.	Common	00817Y108	8,580	47,566	SH		SOLE		47,566	0	0
Affimed N.V.	Common	N01045108	1,827	1,405,324	SH		SOLE		1,405,324	0	0
Alexion Pharmaceuticals, Inc.	Common	015351109	78,884	659,618	SH		SOLE		659,618	0	0
Alkermes plc	Shares	G01767105	7,885	144,072	SH		SOLE		144,072	0	0
Allergan plc	Shares	G0177J108	34,054	208,180	SH		SOLE		208,180	0	0
Allergan plc	5.50% Convertible Preferred Series A	G0177J116	2,931	5,000	SH		SOLE		5,000	0	0
Alliqua BioMedical, Inc.	Common	019621309	302	165,000	SH		SOLE		165,000	0	0
Alnylam Pharmaceuticals, Inc.	Common	02043Q107	14,606	114,966	SH		SOLE		114,966	0	0
Amarin Corporation plc	Sponsored ADR	023111206	3,835	956,300	SH		SOLE		956,300	0	0
AmerisourceBergen Corporation	Common	03073E105	15,362	167,307	SH		SOLE		167,307	0	0
Amgen Inc.	Common	031162100	149,932	862,174	SH		SOLE		862,174	0	0
Amicus Therapeutics, Inc.	Common	03152W109	8,705	604,920	SH		SOLE		604,920	0	0
Anthem, Inc.	Common	036752103	10,107	44,918	SH		SOLE		44,918	0	0
ARCA biopharma, Inc.	Common	00211Y407	1,115	811,227	SH		SOLE		811,227	0	0
Ardelyx, Inc.	Common	039697107	4,220	639,370	SH		SOLE		639,370	0	0
argenx SE	Sponsored ADR	04016X101	2,934	46,466	SH		SOLE		46,466	0	0
AstraZeneca PLC	Sponsored ADR	046353108	15,358	442,600	SH		SOLE		442,600	0	0
Auris Medical Holding AG	Common	H03579101	457	774,504	SH		SOLE		774,504	0	0
Avadel Pharmaceuticals plc	Sponsored ADR	05337M104	5,119	624,288	SH		SOLE		624,288	0	0
AveXis, Inc.	Common	05366U100	7,785	70,347	SH		SOLE		70,347	0	0
BeiGene, Ltd.	Sponsored ADR	07725L102	2,557	26,170	SH		SOLE		26,170	0	0
Bellicum Pharmaceuticals, Inc.	Common	079481107	505	60,000	SH		SOLE		60,000	0	0
BioCryst Pharmaceuticals, Inc.	Common	09058V103	2,206	449,255	SH		SOLE		449,255	0	0
Biogen Inc.	Common	09062X103	141,957	445,607	SH		SOLE		445,607	0	0
BioMarin Pharmaceutical Inc.	Common	09061G101	43,671	489,745	SH		SOLE		489,745	0	0
bluebird bio, Inc.	Common	09609G100	8,387	47,093	SH		SOLE		47,093	0	0
Boston Scientific Corporation	Common	101137107	6,559	264,600	SH		SOLE		264,600	0	0
Bristol-Myers Squibb Company	Common	110122108	21,394	349,121	SH		SOLE		349,121	0	0
Cardinal Health, Inc.	Common	14149Y108	386	6,300	SH		SOLE		6,300	0	0
Cascadian Therapeutics, Inc.	Common	14740B606	2,741	740,769	SH		SOLE		740,769	0	0
Celgene Corporation	Common	151020104	157,991	1,513,904	SH		SOLE		1,513,904	0	0
Celldex Therapeutics, Inc.	Common	15117B103	300	105,800	SH		SOLE		105,800	0	0
Cellectis S.A.	Sponsored ADR	15117K103	9,044	310,250	SH		SOLE		310,250	0	0
Centene Corporation	Common	15135B101	23,218	230,158	SH		SOLE		230,158	0	0
Charles River Laboratories International, Inc.	Common	159864107	9,391	85,804	SH		SOLE		85,804	0	0
Cidara Therapeutics, Inc.	Common	171757107	1,948	286,472	SH		SOLE		286,472	0	0
Cigna Corporation	Common	125509109	20,309	100,002	SH		SOLE		100,002	0	0
Clovis Oncology, Inc.	Common	189464100	5,127	75,400	SH		SOLE		75,400	0	0
Coherus BioSciences, Inc.	Common	19249H103	792	90,000	SH		SOLE		90,000	0	0
Community Health Systems, Inc.	Common	203668108	869	203,935	SH		SOLE		203,935	0	0
CVS Health Corporation	Common	126650100	26,573	366,521	SH		SOLE		366,521	0	0
CymaBay Therapeutics, Inc.	Common	23257D103	1,932	209,962	SH		SOLE		209,962	0	0
Cytokinetics, Inc.	Common	23282W605	2,855	350,300	SH		SOLE		350,300	0	0
CytomX Therapeutics, Inc.	Common	23284F105	5,595	265,045	SH		SOLE		265,045	0	0
Danaher Corporation	Common	235851102	1,411	15,203	SH		SOLE		15,203	0	0
Dermira, Inc.	Common	24983L104	7,467	268,500	SH		SOLE		268,500	0	0
DexCom, Inc.	Common	252131107	3,096	53,950	SH		SOLE		53,950	0	0
Diplomat Pharmacy, Inc.	Common	25456K101	12,855	640,492	SH		SOLE		640,492	0	0
Edwards Lifesciences Corporation	Common	28176E108	7,337	65,100	SH		SOLE		65,100	0	0
Egalet Corporation	Note 5.50% 4/1/20	28226BAB0	3,334	7,000,000	PRN		SOLE		7,000,000	0	0
Eli Lilly & Company	Common	532457108	32,357	383,099	SH		SOLE		383,099	0	0
Endo International plc	Shares	G30401106	7,088	914,548	SH		SOLE		914,548	0	0
Epizyme, Inc.	Common	29428V104	5,723	456,000	SH		SOLE		456,000	0	0
Evolent Health, Inc.	Class A	30050B101	1,507	122,500	SH		SOLE		122,500	0	0
Exelixis, Inc.	Common	30161Q104	11,820	388,822	SH		SOLE		388,822	0	0
Express Scripts Holding Company	Common	30219G108	6,307	84,500	SH		SOLE		84,500	0	0
Foamix Pharmaceuticals Ltd.	Shares	M46135105	5,592	930,398	SH		SOLE		930,398	0	0
Galapagos NV	Sponsored ADR	36315X101	4,988	53,200	SH		SOLE		53,200	0	0
Gilead Sciences, Inc.	Common	375558103	180,553	2,520,281	SH		SOLE		2,520,281	0	0
Glaukos Corporation	Common	377322102	1,413	55,079	SH		SOLE		55,079	0	0
GlaxoSmithKline plc	Shares	37733W105	12,734	359,000	SH		SOLE		359,000	0	0
Global Blood Therapeutics, Inc.	Common	37890U108	5,113	129,948	SH		SOLE		129,948	0	0
Global Medical REIT Inc.	Common	37954A204	602	73,400	SH		SOLE		73,400	0	0
GW Pharmaceuticals plc	ADS	36197T103	3,300	25,000	SH		SOLE		25,000	0	0
HCA Healthcare, Inc.	Common	40412C101	5,572	63,432	SH		SOLE		63,432	0	0
HCP, Inc.	Common	40414L109	1,187	45,500	SH		SOLE		45,500	0	0
Healthcare Realty Trust Incorporated	Common	421946104	2,184	68,000	SH		SOLE		68,000	0	0
Healthcare Trust of America, Inc.	Class A	42225P501	1,382	46,000	SH		SOLE		46,000	0	0
Henry Schein, Inc.	Common	806407102	2,194	31,400	SH		SOLE		31,400	0	0
Horizon Pharma plc	Shares	G4617B105	2,378	162,900	SH		SOLE		162,900	0	0
Humana Inc.	Common	444859102	34,372	138,556	SH		SOLE		138,556	0	0
IDEXX Laboratories, Inc.	Common	45168D104	20,697	132,352	SH		SOLE		132,352	0	0
Illumina, Inc.	Common	452327109	62,442	285,791	SH		SOLE		285,791	0	0
Impax Laboratories, Inc.	Common	45256B101	2,070	124,335	SH		SOLE		124,335	0	0
Incyte Corporation	Common	45337C102	65,660	693,275	SH		SOLE		693,275	0	0
Innoviva, Inc.	Common	45781M101	3,531	248,803	SH		SOLE		248,803	0	0
Intercept Pharmaceuticals, Inc.	Note 3.250% 7/1/23	45845PAA6	5,486	6,900,000	PRN		SOLE		6,900,000	0	0
Intuitive Surgical, Inc.	Common	46120E602	1,405	3,850	SH		SOLE		3,850	0	0
Ionis Pharmaceuticals, Inc.	Common	462222100	6,485	128,930	SH		SOLE		128,930	0	0
Jazz Pharmaceuticals plc	Shares	G50871105	13,252	98,421	SH		SOLE		98,421	0	0
Johnson & Johnson	Common	478160104	102,852	736,132	SH		SOLE		736,132	0	0
Karyopharm Therapeutics Inc.	Common	48576U106	0	20	SH		SOLE		20	0	0
Koninklijke Philips N.V.	NY Registry Shares	500472303	2,646	70,000	SH		SOLE		70,000	0	0
Lexicon Pharmaceuticals, Inc.	Common	528872302	2,754	278,700	SH		SOLE		278,700	0	0
LTC Properties, Inc.	Common	502175102	9,131	209,673	SH		SOLE		209,673	0	0
Mallinckrodt plc	Shares	G5785G107	1,396	61,900	SH		SOLE		61,900	0	0
McKesson Corporation	Common	58155Q103	19,330	123,950	SH		SOLE		123,950	0	0
Medical Properties Trust, Inc.	Common	58463J304	11,831	858,586	SH		SOLE		858,586	0	0
Medtronic plc	Shares	G5960L103	40,862	506,026	SH		SOLE		506,026	0	0
Merck & Co., Inc.	Common	58933Y105	74,400	1,322,195	SH		SOLE		1,322,195	0	0
Merus B.V.	Common	N5749R100	9,276	479,150	SH		SOLE		479,150	0	0
Mylan N.V.	Shares	N59465109	67,828	1,603,112	SH		SOLE		1,603,112	0	0
Myovant Sciences Ltd.	Common	G637AM102	5,056	400,000	SH		SOLE		400,000	0	0
NanoString Technologies, Inc.	Common	63009R109	555	74,250	SH		SOLE		74,250	0	0
Natera, Inc.	Common	632307104	4,367	485,758	SH		SOLE		485,758	0	0
Neurocrine Biosciences, Inc.	Common	64125C109	25,222	325,067	SH		SOLE		325,067	0	0
Nevro Corp.	Common	64157F103	13,437	194,621	SH		SOLE		194,621	0	0
New Senior Investment Group Inc.	Common	648691103	6,682	883,919	SH		SOLE		883,919	0	0
Novartis AG	Sponsored ADR	66987V109	32,063	381,882	SH		SOLE		381,882	0	0
Novavax, Inc.	Common	670002104	708	571,000	SH		SOLE		571,000	0	0
Novo Nordisk A/S	Sponsored ADR	670100205	14,588	271,800	SH		SOLE		271,800	0	0
NuVasive, Inc.	Common	670704105	6,869	117,437	SH		SOLE		117,437	0	0
Omega Healthcare Investors, Inc.	Common	681936100	15,967	579,785	SH		SOLE		579,785	0	0
Ovid Therapeutics Inc.	Common	690469101	5,289	535,824	SH		SOLE		535,824	0	0
Perrigo Company plc	Shares	G97822103	3,251	37,300	SH		SOLE		37,300	0	0
Pfizer Inc.	Common	717081103	35,318	975,087	SH		SOLE		975,087	0	0
Physicians Realty Trust	Common	71943U104	4,773	265,336	SH		SOLE		265,336	0	0
Pieris Pharmaceuticals, Inc.	Common	720795103	14,816	1,962,380	SH		SOLE		1,962,380	0	0
PRA Health Sciences, Inc.	Common	69354M108	5,912	64,920	SH		SOLE		64,920	0	0
Protagonist Therapeutics, Inc.	Common	74366E102	1,723	82,822	SH		SOLE		82,822	0	0
Puma Biotechnology, Inc.	Common	74587V107	4,784	48,392	SH		SOLE		48,392	0	0
Quorum Health Corporation	Shares	74909E106	148	23,725	SH		SOLE		23,725	0	0
Quotient Limited	Common	G73268107	1,037	209,519	SH		SOLE		209,519	0	0
Ra Pharmaceuticals, Inc.	Common	74933V108	3,028	356,237	SH		SOLE		356,237	0	0
Regeneron Pharmaceuticals, Inc.	Common	75886F107	64,107	170,516	SH		SOLE		170,516	0	0
Revance Therapeutics, Inc.	Common	761330109	1,152	32,225	SH		SOLE		32,225	0	0
The RMR Group Inc.	Class A	74967R106	441	7,441	SH		SOLE		7,441	0	0
Sabra Health Care REIT, Inc.	Common	78573L106	13,601	724,606	SH		SOLE		724,606	0	0
Sage Therapeutics, Inc.	Common	78667J108	11,170	67,815	SH		SOLE		67,815	0	0
Sanofi	Sponsored ADR	80105N105	7,736	179,900	SH		SOLE		179,900	0	0
Sarepta Therapeutics, Inc.	Common	803607100	18,606	334,400	SH		SOLE		334,400	0	0
Seattle Genetics, Inc.	Common	812578102	11,968	223,700	SH		SOLE		223,700	0	0
Senior Housing Properties Trust	Shares	81721M109	12,382	646,554	SH		SOLE		646,554	0	0
Shire plc	Sponsored ADR	82481R106	31,294	201,739	SH		SOLE		201,739	0	0
Smith & Nephew plc	Sponsored ADR	83175M205	1,407	40,183	SH		SOLE		40,183	0	0
Spark Therapeutics, Inc.	Common	84652J103	1,990	38,706	SH		SOLE		38,706	0	0
SPDR S&P Biotech ETF	S&P Biotech ETF	78464A870	19,220	226,460	SH		SOLE		226,460	0	0
Stryker Corporation	Common	863667101	4,877	31,500	SH		SOLE		31,500	0	0
Syndax Pharmaceuticals, Inc.	Common	87164F105	1,752	200,000	SH		SOLE		200,000	0	0
Tenet Healthcare Corporation	Common	88033G407	2,494	164,500	SH		SOLE		164,500	0	0
TESARO, Inc.	Common	881569107	4,773	57,595	SH		SOLE		57,595	0	0
Tetraphase Pharmaceuticals, Inc.	Common	88165N105	5,414	859,322	SH		SOLE		859,322	0	0
Teva Pharmaceutical Industries Ltd.	Sponsored ADR	881624209	30,000	1,583,108	SH		SOLE		1,583,108	0	0
TherapeuticsMD, Inc.	Common	88338N107	2,537	420,000	SH		SOLE		420,000	0	0
Thermo Fisher Scientific Inc.	Common	883556102	26,197	137,968	SH		SOLE		137,968	0	0
Trillium Therapeutics Inc.	Common	89620X506	3,285	450,000	SH		SOLE		450,000	0	0
Ultragenyx Pharmaceutical Inc.	Shares	90400D108	6,890	148,558	SH		SOLE		148,558	0	0
uniQure N.V.	Common	N90064101	6,521	332,850	SH		SOLE		332,850	0	0
United Therapeutics Corporation	Common	91307C102	2,400	16,220	SH		SOLE		16,220	0	0
UnitedHealth Group Inc.	Class B	91324P102	67,436	305,886	SH		SOLE		305,886	0	0
Valeant Pharmaceuticals International, Inc.	Common	91911K102	3,990	192,000	SH		SOLE		192,000	0	0
Ventas, Inc.	Common	92276F100	5,281	87,996	SH		SOLE		87,996	0	0
Verona Pharma plc	Sponsored ADR	925050106	3,278	275,000	SH		SOLE		275,000	0	0
Vertex Pharmaceuticals Incorporated	Common	92532F100	96,474	643,762	SH		SOLE		643,762	0	0
Welltower Inc.	6.50% Preferred Perpetual	95040Q203	11,974	200,000	SH		SOLE		200,000	0	0
Welltower Inc.	Common	95040Q104	1,365	21,400	SH		SOLE		21,400	0	0
Wright Medical Group N.V.	Ordinary Shares	N96617118	5,923	266,781	SH		SOLE		266,781	0	0
Xencor, Inc.	Common	98401F105	438	20,000	SH		SOLE		20,000	0	0
Xenon Pharmaceuticals Inc.	Common	98420N105	989	350,000	SH		SOLE		350,000	0	0
Zafgen, Inc.	Common	98885E103	61	13,307	SH		SOLE		13,307	0	0
Zimmer Biomet Holdings, Inc.	Common	98956P102	9,690	80,300	SH		SOLE		80,300	0	0