Stock Incentive Plans | 6. Stock Incentive Plans Equity Incentive Award and Stock Incentive Plans As of June 30, 2015, a total of 2,981,839 shares of common stock have been authorized under the 2013 Equity Incentive Award Plan (the “2013 Plan”), including the additional 1,193,903 shares of common stock that became available for future issuance under the 2013 Plan as of January 1, 2015 as a result of an annual automatic increase provision in the 2013 Plan. As of June 30, 2015, a total of 1,590,627 shares are subject to options outstanding under the 2013 Plan. There are 1,899,557 shares subject to options outstanding under the 2004 Stock Incentive Plan (the “2004 Plan”) as of June 30, 2015, which will become available for issuance under the 2013 Plan to the extent the options are forfeited or lapse unexercised without issuance of such shares under the 2004 Plan. The following table summarizes activity under 2004 Plan and 2013 Plan during the six months ended June 30, 2015, including grants to nonemployees and restricted stock units (“RSUs”) granted: (In thousands) Shares Available for Grant of Options and Options and Balance at December 31, 2014 19 3,822 Additional shares authorized 1,194 — Options granted (171 ) 171 Options exercised — (163 ) Options forfeited 46 (46 ) RSUs forfeited 5 (5 ) Balance at June 30, 2015 1,093 3,779 The weighted-average grant date estimated fair value of options granted during the six months ended June 30, 2015 was $15.15 per share. Employee Stock Purchase Plan As of June 30, 2015, a total of 892,454 shares of common stock have been authorized and 783,121 shares of common stock are available for future issuance under the Company’s Employee Stock Purchase Plan (the “ESPP”). This authorized number includes the additional 298,475 shares of common stock that became available for future issuance under the ESPP as of January 1, 2015 as a result of an annual automatic increase provision in the ESPP. The ESPP allows eligible employees to purchase shares of the Company’s common stock at a discount through payroll deductions of up to 15% of their eligible compensation, subject to any plan limitations. The ESPP provides for six-month offering periods, and at the end of each offering period, employees are able to purchase shares at 85% of the lower of the fair market value of the Company’s common stock on the first trading day of the offering period or on the last day of the offering period. During the six months ended June 30, 2015, the Company issued 43,424 shares under the ESPP. The Company used the following assumptions to estimate the fair value of the ESPP offered during the six months ended June 30, 2015: expected term of 0.5 years, weighted-average volatility from 51.1% to 72.5%, risk-free interest rate from 0.05% to 0.08% and expected dividend yield of zero. Restricted Stock Units In March 2014, the Company awarded 293,980 RSUs under the 2013 Plan. Each vested RSU represents the right to receive one share of common stock. The fair value of the RSU awards was calculated based on the NASDAQ quoted stock price on the date of the grant with the expense being recognized over the vesting period. The RSUs are generally scheduled to vest at the end of three years at March 31, 2017. However, the vesting will be accelerated to 25% of the awarded RSUs upon the payment by Celgene of a designated milestone payment related to Phase II clinical trials of demcizumab (anti-DLL4, OMP-21M18). The stock-based compensation expense for these RSUs is being amortized on the straight-line basis over the three-year vesting period. The Company continues to assess at each reporting date whether achievement of any performance condition is probable and would begin recognizing compensation costs based on the accelerated vesting if and when achievement of the performance condition becomes probable. The Company has recognized the stock-based compensation expense of $0.7 million and $1.4 million related to these RSUs for the three and six months ended June 30, 2015, respectively. There were no RSUs awarded during the six months ended June 30, 2015. Stock-Based Compensation Employee stock-based compensation expense was calculated based on awards expected to vest and has been reduced for estimated forfeitures. Forfeitures are estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates. Stock-based compensation expense recognized was as follows (in thousands): Three Months Ended June 30, Six Months Ended June 30, 2015 2014 2015 2014 Research and development $ 1,326 $ 977 $ 2,650 $ 1,388 General and administrative 1,091 530 2,154 809 Total $ 2,417 $ 1,507 $ 4,804 $ 2,197 As of June 30, 2015, the Company had $15.5 million and $5.2 million of unrecognized compensation expense related to unvested stock options and RSUs, respectively, which are expected to be recognized over an estimated weighted-average period of 2.78 years and 1.75 years, respectively. The estimated grant date fair value of employee stock options was calculated using the Black-Scholes option-pricing model, based on the following assumptions: Three Months Ended June 30, Six Months Ended June 30, 2015 2014 2015 2014 Weighted-average volatility 63.75 % 69.45 % 63.88 % 69.65 % Weighted-average expected term (years) 6.20 6.20 6.20 6.20 Risk-free interest rate 2.03 % 2.22 % 2.00 % 2.23 % Expected dividend yield — — — — |