Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands | Total | Common Stock [Member] | Additional Paid-In Capital [Member] | Accumulated Other Comprehensive Income (Loss) [Member] | Accumulated Deficit [Member] |
Balance at Dec. 31, 2018 | $ 66,592 | $ 19 | $ 237,795 | $ (25) | $ (171,197) |
Balance, beginning of period, Shares at Dec. 31, 2018 | | 19,211,759 | | | |
Issuance of common stock upon exercise of stock options | 65 | | 65 | | |
Issuance of common stock upon exercise of stock options, Shares | | 41,546 | | | |
Vesting of common stock issued under Product Development Agreement | 56 | | 56 | | |
Issuance of common stock upon ESPP purchase | 59 | | 59 | | |
Issuance of common stock upon ESPP purchase, Shares | | 7,138 | | | |
Stock-based compensation expense | 1,195 | | 1,195 | | |
Unrealized gain (loss) on debt securities, net | 30 | | | 30 | |
Net loss | (17,189) | | | | (17,189) |
Balance at Mar. 31, 2019 | 50,808 | $ 19 | 239,170 | 5 | (188,386) |
Balance, end of period, Shares at Mar. 31, 2019 | | 19,260,443 | | | |
Balance at Dec. 31, 2018 | 66,592 | $ 19 | 237,795 | (25) | (171,197) |
Balance, beginning of period, Shares at Dec. 31, 2018 | | 19,211,759 | | | |
Unrealized gain (loss) on debt securities, net | 68 | | | | |
Net loss | (53,332) | | | | |
Balance at Sep. 30, 2019 | 71,659 | $ 24 | 296,121 | 43 | (224,529) |
Balance, end of period, Shares at Sep. 30, 2019 | | 24,494,185 | | | |
Balance at Mar. 31, 2019 | 50,808 | $ 19 | 239,170 | 5 | (188,386) |
Balance, beginning of period, Shares at Mar. 31, 2019 | | 19,260,443 | | | |
Issuance of common stock upon exercise of stock options | 62 | | 62 | | |
Issuance of common stock upon exercise of stock options, Shares | | 10,304 | | | |
Vesting of common stock issued under Product Development Agreement | 55 | | 55 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs | 53,194 | $ 5 | 53,189 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs, Shares | | 5,175,000 | | | |
Stock-based compensation expense | 1,487 | | 1,487 | | |
Net loss | (17,527) | | | | (17,527) |
Balance at Jun. 30, 2019 | 88,079 | $ 24 | 293,963 | 5 | (205,913) |
Balance, end of period, Shares at Jun. 30, 2019 | | 24,445,747 | | | |
Issuance of common stock upon exercise of stock options | 379 | | 379 | | |
Issuance of common stock upon exercise of stock options, Shares | | 39,875 | | | |
Vesting of common stock issued under Product Development Agreement | 59 | | 59 | | |
Issuance of common stock upon ESPP purchase | 71 | | 71 | | |
Issuance of common stock upon ESPP purchase, Shares | | 8,563 | | | |
Stock-based compensation expense | 1,649 | | 1,649 | | |
Unrealized gain (loss) on debt securities, net | 38 | | | 38 | |
Net loss | (18,616) | | | | (18,616) |
Balance at Sep. 30, 2019 | 71,659 | $ 24 | 296,121 | 43 | (224,529) |
Balance, end of period, Shares at Sep. 30, 2019 | | 24,494,185 | | | |
Balance at Dec. 31, 2019 | 56,480 | $ 24 | 297,863 | 42 | (241,449) |
Balance, beginning of period, Shares at Dec. 31, 2019 | | 24,523,381 | | | |
Issuance of common stock upon exercise of stock options | 30 | | 30 | | |
Issuance of common stock upon exercise of stock options, Shares | | 2,895 | | | |
Vesting of common stock issued under Product Development Agreement | 53 | | 53 | | |
Issuance of common stock upon ESPP purchase | 83 | | 83 | | |
Issuance of common stock upon ESPP purchase, Shares | | 11,332 | | | |
Issuance of common stock upon offering at-the-market, net of issuance costs | 191 | | 191 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs, Shares | | 32,751 | | | |
Stock-based compensation expense | 1,629 | | 1,629 | | |
Unrealized gain (loss) on debt securities, net | (6) | | | (6) | |
Net loss | (15,239) | | | | (15,239) |
Balance at Mar. 31, 2020 | 43,221 | $ 24 | 299,849 | 36 | (256,688) |
Balance, end of period, Shares at Mar. 31, 2020 | | 24,570,359 | | | |
Balance at Dec. 31, 2019 | $ 56,480 | $ 24 | 297,863 | 42 | (241,449) |
Balance, beginning of period, Shares at Dec. 31, 2019 | | 24,523,381 | | | |
Issuance of common stock upon exercise of stock options, Shares | 61,700 | | | | |
Unrealized gain (loss) on debt securities, net | $ (26) | | | | |
Net loss | (46,245) | | | | |
Balance at Sep. 30, 2020 | 92,950 | $ 32 | 380,596 | 16 | (287,694) |
Balance, end of period, Shares at Sep. 30, 2020 | | 31,916,039 | | | |
Balance at Mar. 31, 2020 | 43,221 | $ 24 | 299,849 | 36 | (256,688) |
Balance, beginning of period, Shares at Mar. 31, 2020 | | 24,570,359 | | | |
Issuance of common stock upon exercise of stock options | 490 | | 490 | | |
Issuance of common stock upon exercise of stock options, Shares | | 58,805 | | | |
Vesting of common stock issued under Product Development Agreement | 55 | | 55 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs | 28,580 | $ 3 | 28,577 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs, Shares | | 2,612,476 | | | |
Stock-based compensation expense | 1,462 | | 1,462 | | |
Unrealized gain (loss) on debt securities, net | 9 | | | 9 | |
Net loss | (15,326) | | | | (15,326) |
Balance at Jun. 30, 2020 | 58,491 | $ 27 | 330,433 | 45 | (272,014) |
Balance, end of period, Shares at Jun. 30, 2020 | | 27,241,640 | | | |
Vesting of common stock issued under Product Development Agreement | 56 | | 56 | | |
Issuance of common stock upon ESPP purchase | 103 | | 103 | | |
Issuance of common stock upon ESPP purchase, Shares | | 14,313 | | | |
Issuance of common stock upon offering at-the-market, net of issuance costs | 48,564 | $ 5 | 48,559 | | |
Issuance of common stock upon offering at-the-market, net of issuance costs, Shares | | 4,660,086 | | | |
Stock-based compensation expense | 1,445 | | 1,445 | | |
Unrealized gain (loss) on debt securities, net | (29) | | | (29) | |
Net loss | (15,680) | | | | (15,680) |
Balance at Sep. 30, 2020 | $ 92,950 | $ 32 | $ 380,596 | $ 16 | $ (287,694) |
Balance, end of period, Shares at Sep. 30, 2020 | | 31,916,039 | | | |