Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement Nos.333-152146,333-163208 and333-216166 and333-227525 on FormS-8 and Registration Nos.333-226341 and333-228581 on FormS-3 of our reports dated March 18, 2019, relating to the financial statements of EyePoint Pharmaceuticals, Inc. (which report expresses an unqualified opinion and includes explanatory paragraphs relating to a change in accounting principle and going concern), and the effectiveness of Eyepoint Pharmaceutical Inc.’s internal control over financial reporting, appearing in this Transition Report on Form10-K of EyePoint Pharmaceuticals, Inc. for the six months ended December 31, 2018.
/s/ Deloitte & Touche LLP
Boston, Massachusetts
March 18, 2019