Investments and Fair Value of Financial Instruments | 3. Investments and Fair Value of Financial Instruments Marketable Investments The Company’s marketable investments have been classified and accounted for as available-for-sale. The following table presents the Company’s marketable investments as of March 31, 2021 and December 31, 2020 (in thousands): March 31, 2021 Securities with net gains or losses in accumulated other comprehensive income (loss) Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Allowance Fair Value Commercial paper $ 4,247 $ 2 $ — $ — $ 4,249 U.S. agency and government sponsored securities 4,548 7 — — 4,555 U.S. states and municipalities 47,283 148 (6) — 47,425 Corporate bonds 130,411 396 (59) — 130,748 Total $ 186,489 $ 553 $ (65) $ — $ 186,977 December 31, 2020 Securities with net gains or losses in accumulated other comprehensive income (loss) Amortized Cost Gross Unrealized Gains Gross Unrealized Losses Allowance Fair Value Commercial paper $ 4,242 $ 4 $ — $ — $ 4,246 U.S. agency and government sponsored securities 7,846 11 — — 7,857 U.S. states and municipalities 47,934 162 (1) — 48,095 Corporate bonds 134,298 669 (3) — 134,964 Total $ 194,320 $ 846 $ (4) $ — $ 195,162 As of March 31, 2021, the total amortized cost basis of the Company’s impaired available-for-sale securities exceeded its fair value by a nominal amount. The Company reviewed its impaired available-for-sale securities and concluded that the decline in fair value was not related to credit losses and is recoverable. Accordingly, during the three months ended March 31, 2021 no allowance for credit losses was recorded and instead the unrealized losses are reported as a component of accumulated other comprehensive loss. The following tables present the gross unrealized losses and the fair value for those marketable investments that were in an unrealized loss position for less than twelve months or for twelve months or more as of March 31, 2021 and December 31, 2020 (in thousands): March 31, 2021 Less than 12 months 12 months or more Total Fair Value Gross Unrealized Losses Fair Value Gross Unrealized Losses Fair Value Gross Unrealized Losses U.S. states and municipalities $ 3,590 $ (6) $ — $ — $ 3,590 $ (6) Corporate bonds 32,127 (59) — — 32,127 (59) Total $ 35,717 $ (65) $ — $ — $ 35,717 $ (65) December 31, 2020 Less than 12 months 12 months or more Total Fair Value Gross Unrealized Losses Fair Value Gross Unrealized Losses Fair Value Gross Unrealized Losses U.S. states and municipalities 1,408 (1) — — 1,408 (1) Corporate bonds $ 12,552 $ (3) $ — $ — $ 12,552 $ (3) Total $ 13,960 $ (4) $ — $ — $ 13,960 $ (4) The following table presents the contractual maturities of the Company’s marketable investments as of March 31, 2021 (in thousands): March 31, 2021 Amortized Cost Fair Value Due in less than one year $ 100,191 $ 100,403 Due in one to five years 86,298 86,574 Total $ 186,489 $ 186,977 Fair Value of Financial Instruments Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability (an exit price) in an orderly transaction between market participants at the measurement date. The accounting guidance establishes a three-tiered hierarchy, which prioritizes the inputs used in the valuation methodologies in measuring fair value: Level 1 - Quoted prices in active markets for identical assets or liabilities. Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities. Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities. The categorization of a financial instrument within the valuation hierarchy is based on the lowest level of input that is significant to the fair value measurement. The Company classifies its cash equivalents and marketable investments within Level 1 and Level 2, as it uses quoted market prices or alternative pricing sources and models utilizing market observable inputs. The Company determined the fair value of its Level 1 financial instruments, which are traded in active markets, using quoted market prices for identical instruments. Marketable investments classified within Level 2 of the fair value hierarchy are valued based on other observable inputs, including broker or dealer quotations or alternative pricing sources. When quoted prices in active markets for identical assets or liabilities are not available, the Company relies on non-binding quotes from its investment managers, which are based on proprietary valuation models of independent pricing services. These models generally use inputs such as observable market data, quoted market prices for similar instruments, historical pricing trends of a security as relative to its peers. To validate the fair value determination provided by its investment managers, the Company reviews the pricing movement in the context of overall market trends and trading information from its investment managers. In addition, the Company assesses the inputs and methods used in determining the fair value in order to determine the classification of securities in the fair value hierarchy. The Company did not hold any Level 3 marketable investments as of March 31, 2021 or December 31, 2020. During the three months ended March 31, 2021 and 2020, the Company did not have any transfers between Level 1, Level 2 or Level 3 of the fair value hierarchy. Additionally, the Company did not have any financial assets and liabilities measured at fair value on a non-recurring basis as of March 31, 2021 or December 31, 2020. The following tables set forth the Company’s financial assets measured at fair value by level within the fair value hierarchy as of March 31, 2021 and December 31, 2020 (in thousands): As of March 31, 2021 Level 1 Level 2 Level 3 Fair Value Financial Assets Cash equivalents: Money market funds $ 11,056 $ — $ — $ 11,056 Marketable investments: Commercial paper — 4,249 — 4,249 U.S. agency and government sponsored securities — 4,555 — 4,555 U.S. states and municipalities — 47,425 — 47,425 Corporate bonds — 130,748 — 130,748 Total $ 11,056 $ 186,977 $ — $ 198,033 As of December 31, 2020 Level 1 Level 2 Level 3 Fair Value Financial Assets Cash equivalents: Money market funds 33,054 — — 33,054 Marketable investments: Commercial paper — 4,246 — 4,246 U.S. agency and government sponsored securities — 7,857 — 7,857 U.S. states and municipalities — 48,095 — 48,095 Corporate bonds — 134,964 — 134,964 Total $ 33,054 $ 195,162 $ — $ 228,216 Contingent Consideration Obligations As of March 31, 2021 and December 31, 2020, there were no contingent consideration liabilities classified as Level 3. The Company had a contingent consideration liability balance of $1.2 million related to milestone payments due in connection with the 2017 acquisition of Crossmed S.p.a. (“Crossmed”) and was based on actual revenue performance for the year ended December 31, 2019 and not based on unobservable inputs. The Company made this payment during the three months ended March 31, 2020 of which $0.5 million is presented in operating activities and $0.7 million is presented in financing activities in the condensed consolidated statement of cash flows. The following table summarizes the changes in fair value of the contingent consideration obligation for the three months ended March 31, 2020 (in thousands): Fair Value of Contingent Consideration Balance at December 31, 2019 $ 1,206 Payments of contingent consideration liabilities (1,186) Changes in fair value — Foreign currency remeasurement (20) Balance at March 31, 2020 $ — |