Federal Home Loan Bank of Des Moines 10-Q 2021 Q3 Quarterly report

EXHIBIT 32.2

Certification by the Executive Vice President and Chief Financial Officer

Pursuant to 18 U.S.C. Section 1350,

as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

I, Joelyn R. Jensen-Marren, Executive Vice President and Chief Financial Officer of the Federal Home Loan Bank of Des Moines (“Registrant”) certify that, to the best of my knowledge:

1 The Registrant's Quarterly Report on Form 10-Q for the period ended September 30, 2021 (“Report”), fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

2 The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Registrant.

Date: November 9, 2021	/s/ Joelyn R. Jensen-Marren
	Joelyn R. Jensen-Marren
	Executive Vice President and Chief Financial Officer