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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement No. 333-192635 on Form S-8 and Registration Statement No. 333-201384 on Form S-3 of Xencor, Inc. of our report dated March 8, 2016 relating to our audit of the financial statements, which appears in this Annual Report on Form 10-K of Xencor, Inc. for the year ended December 31, 2015.
/s/ RSM US LLP
Los Angeles, California
March 8, 2016