Exhibit 15.1
Awareness of Independent Registered
Public Accounting Firm
We acknowledge the incorporation by reference in the November 30, 2018, Registration Statement on FormS-3 of Home BancShares, Inc. of our reports dated May 7, 2018, August 6, 2018 and November 5, 2018, included with the Quarterly Report on Form10-Q for the quarters ended March 31, 2018, June 30, 2018 and September 30, 2018. Pursuant to Rule 436(c) under theSecurities Act of 1933 (the Act), these reports should not be considered a part of the registration statement prepared or certified by us within the meaning ofSections 7 and11 of the Act.
/s/ BKD, LLP
Little Rock, Arkansas
November 30, 2018