Statements of Stockholders' Equity (Deficit) (USD $) | Total | Convertible Preferred Stock Series A-4 [Member] | Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Convertible Preferred Stock [Member] | Common Stock [Member] | Additional Paid-in Capital [Member] | Deficit Accumulated During Development Stage [Member] |
In Thousands, except Share data | Convertible Preferred Stock Series A-1 [Member] | Convertible Preferred Stock Series A-2 [Member] | Convertible Preferred Stock Series A-3 [Member] | Convertible Preferred Stock Series A-4 [Member] | Convertible Preferred Stock Series B [Member] |
Beginning balance, Value at Jun. 22, 2005 | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' |
Beginning balance, Shares at Jun. 22, 2005 | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' |
Issuance of common stock, value | 3 | ' | ' | ' | ' | ' | ' | ' | 1 | 2 | ' |
Issuance of common stock, shares | ' | ' | ' | ' | ' | ' | ' | ' | 521,600 | ' | ' |
Issuance of common stock for services and license agreement, Value | 1 | ' | ' | ' | ' | ' | ' | ' | ' | 1 | ' |
Issuance of common stock for services and license agreement, Shares | ' | ' | ' | ' | ' | ' | ' | ' | 118,400 | ' | ' |
Issuance of convertible preferred stock, net of issuance costs, Value | ' | ' | ' | ' | 9,957 | ' | ' | ' | ' | ' | ' |
Issuance of convertible preferred stock, net of issuance costs, Shares | ' | ' | ' | ' | 2,000,000 | ' | ' | ' | ' | ' | ' |
Accretion of stock issuance costs | -2 | ' | 2 | ' | ' | ' | ' | ' | ' | -2 | ' |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Shares | ' | ' | ' | 400,000 | ' | ' | ' | ' | ' | ' | ' |
Net loss | -766 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -766 |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Value | ' | ' | ' | 996 | ' | ' | ' | ' | ' | ' | ' |
Ending balance, Value at Dec. 31, 2005 | -764 | ' | 10,955 | ' | ' | ' | ' | ' | 1 | 1 | -766 |
Ending balance, Shares at Dec. 31, 2005 | ' | ' | 2,400,000 | ' | ' | ' | ' | ' | 640,000 | ' | ' |
Stock-based compensation | 4 | ' | ' | ' | ' | ' | ' | ' | ' | 4 | ' |
Accretion of stock issuance costs | -10 | ' | 10 | ' | ' | ' | ' | ' | ' | -9 | -1 |
Issuance of common stock upon net exercise of warrants, value | 4 | ' | ' | ' | ' | ' | ' | ' | ' | 4 | ' |
Net loss | -4,078 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -4,078 |
Ending balance, Value at Dec. 31, 2006 | -4,844 | ' | 10,965 | ' | ' | ' | ' | ' | 1 | ' | -4,845 |
Ending balance, Shares at Dec. 31, 2006 | ' | ' | 2,400,000 | ' | ' | ' | ' | ' | 640,000 | ' | ' |
Exercise of stock options, value | 1 | ' | ' | ' | ' | ' | ' | ' | ' | 1 | ' |
Exercise of stock options, shares | ' | ' | ' | ' | ' | ' | ' | ' | 17,200 | ' | ' |
Stock-based compensation | 3 | ' | ' | ' | ' | ' | ' | ' | ' | 3 | ' |
Issuance of convertible preferred stock, net of issuance costs, Value | ' | ' | ' | ' | ' | 9,991 | ' | ' | ' | ' | ' |
Issuance of convertible preferred stock, net of issuance costs, Shares | ' | ' | ' | ' | ' | 2,000,000 | ' | ' | ' | ' | ' |
Accretion of stock issuance costs | -10 | ' | 10 | ' | ' | ' | ' | ' | ' | -4 | -6 |
Net loss | -6,668 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -6,668 |
Ending balance, Value at Dec. 31, 2007 | -11,518 | ' | 20,966 | ' | ' | ' | ' | ' | 1 | ' | -11,519 |
Ending balance, Shares at Dec. 31, 2007 | ' | ' | 4,400,000 | ' | ' | ' | ' | ' | 657,200 | ' | ' |
Exercise of stock options, value | 1 | ' | ' | ' | ' | ' | ' | ' | ' | 1 | ' |
Exercise of stock options, shares | ' | ' | ' | ' | ' | ' | ' | ' | 149,296 | ' | ' |
Stock-based compensation | 20 | ' | ' | ' | ' | ' | ' | ' | ' | 20 | ' |
Accretion of stock issuance costs | -11 | ' | 11 | ' | ' | ' | ' | ' | ' | -11 | ' |
Net loss | -7,795 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -7,795 |
Ending balance, Value at Dec. 31, 2008 | -19,303 | ' | 20,977 | ' | ' | ' | ' | ' | 1 | 10 | -19,314 |
Ending balance, Shares at Dec. 31, 2008 | ' | ' | 4,400,000 | ' | ' | ' | ' | ' | 806,496 | ' | ' |
Exercise of stock options, value | 1 | ' | ' | ' | ' | ' | ' | ' | ' | 1 | ' |
Exercise of stock options, shares | ' | ' | ' | ' | ' | ' | ' | ' | 90,830 | ' | ' |
Stock-based compensation | 105 | ' | ' | ' | ' | ' | ' | ' | ' | 105 | ' |
Accretion of stock issuance costs | -11 | ' | 11 | ' | ' | ' | ' | ' | ' | -11 | ' |
Net loss | -7,998 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -7,998 |
Ending balance, Value at Dec. 31, 2009 | -27,206 | ' | 20,988 | ' | ' | ' | ' | ' | 1 | 105 | -27,312 |
Ending balance, Shares at Dec. 31, 2009 | ' | ' | 4,400,000 | ' | ' | ' | ' | ' | 897,326 | ' | ' |
Exercise of stock options, value | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' | ' |
Exercise of stock options, shares | ' | ' | ' | ' | ' | ' | ' | ' | 27,350 | ' | ' |
Stock-based compensation | 173 | ' | ' | ' | ' | ' | ' | ' | ' | 173 | ' |
Accretion of stock issuance costs | -12 | ' | 12 | ' | ' | ' | ' | ' | ' | -12 | ' |
Net loss | -8,528 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -8,528 |
Ending balance, Value at Dec. 31, 2010 | -35,573 | ' | 21,000 | ' | ' | ' | ' | ' | 1 | 266 | -35,840 |
Ending balance, Shares at Dec. 31, 2010 | ' | ' | 4,400,000 | ' | ' | ' | ' | ' | 924,676 | ' | ' |
Exercise of stock options, value | 6 | ' | ' | ' | ' | ' | ' | ' | ' | 6 | ' |
Exercise of stock options, shares | 27,297 | ' | ' | ' | ' | ' | ' | ' | 27,297 | ' | ' |
Stock-based compensation | 295 | ' | ' | ' | ' | ' | ' | ' | ' | 295 | ' |
Accretion from conversion of note payable to related parties | -243 | ' | 243 | ' | ' | ' | ' | ' | ' | -243 | ' |
Issuance of convertible preferred stock, net of issuance costs, Value | ' | ' | ' | ' | ' | ' | ' | 23,840 | ' | ' | ' |
Issuance of convertible preferred stock, net of issuance costs, Shares | ' | ' | ' | ' | ' | ' | ' | 4,545,455 | ' | ' | ' |
Accretion of stock issuance costs | -215 | ' | 215 | ' | ' | ' | ' | ' | ' | -215 | ' |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Shares | ' | ' | ' | ' | ' | 2,195,895 | 979,181 | ' | ' | ' | ' |
Net loss | -12,967 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -12,967 |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Value | ' | ' | ' | ' | ' | 10,979 | 4,071 | ' | ' | ' | ' |
Ending balance, Value at Dec. 31, 2011 | -48,697 | ' | 60,348 | ' | ' | ' | ' | ' | 1 | 109 | -48,807 |
Ending balance, Shares at Dec. 31, 2011 | ' | ' | 12,120,531 | ' | ' | ' | ' | ' | 951,973 | ' | ' |
Exercise of stock options, value | 6 | ' | ' | ' | ' | ' | ' | ' | ' | 6 | ' |
Exercise of stock options, shares | 12,907 | ' | ' | ' | ' | ' | ' | ' | 12,907 | ' | ' |
Stock-based compensation | 430 | ' | ' | ' | ' | ' | ' | ' | ' | 430 | ' |
Accretion from conversion of note payable to related parties | -292 | -292 | 292 | ' | ' | ' | ' | ' | ' | -290 | -2 |
Accretion of stock issuance costs | -258 | ' | 258 | ' | ' | ' | ' | ' | ' | -255 | -3 |
Cash dividend | -130 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -130 |
Net loss | -14,978 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -14,978 |
Ending balance, Value at Dec. 31, 2012 | -63,919 | ' | 60,898 | ' | ' | ' | ' | ' | 1 | ' | -63,920 |
Ending balance, Shares at Dec. 31, 2012 | ' | ' | 12,120,531 | ' | ' | ' | ' | ' | 964,880 | ' | ' |
Exercise of stock options, value | 1 | ' | ' | ' | ' | ' | ' | ' | ' | 1 | ' |
Exercise of stock options, shares | 3,195 | ' | ' | ' | ' | ' | ' | ' | 3,195 | ' | ' |
Issuance of common stock, value | 68,226 | ' | ' | ' | ' | ' | ' | ' | 8 | 68,218 | ' |
Vesting of restricted stock | ' | ' | ' | ' | ' | ' | ' | ' | 124,966 | ' | ' |
Issuance of common stock, shares | ' | ' | ' | ' | ' | ' | ' | ' | 7,728,000 | ' | ' |
Stock-based compensation | 2,858 | ' | ' | ' | ' | ' | ' | ' | ' | 2,858 | ' |
Accretion from conversion of note payable to related parties | -240 | -240 | 240 | ' | ' | ' | ' | ' | ' | -240 | ' |
Accretion of stock issuance costs | -210 | ' | 210 | ' | ' | ' | ' | ' | ' | -210 | ' |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Value | 61,348 | ' | -61,348 | ' | ' | ' | ' | ' | 12 | 61,336 | ' |
Issuance of convertible preferred stock for debt conversion, net of issuance costs, Shares | ' | ' | -12,120,531 | ' | ' | ' | ' | ' | 12,120,531 | ' | ' |
Conversion of convertible notes payable and accrued interest to common stock | 18,604 | ' | ' | ' | ' | ' | ' | ' | 2 | 18,602 | ' |
Conversion of convertible notes payable and accrued interest to common stock, shares | ' | ' | ' | ' | ' | ' | ' | ' | 1,860,363 | ' | ' |
Issuance of common stock upon net exercise of warrants, value | 4,896 | ' | ' | ' | ' | ' | ' | ' | ' | 4,896 | ' |
Issuance of common stock upon net exercise of warrants, shares | ' | ' | ' | ' | ' | ' | ' | ' | 483,614 | ' | ' |
Reclassification of warrants from liabilities to equity | 6,560 | ' | ' | ' | ' | ' | ' | ' | ' | 6,560 | ' |
Net loss | -31,148 | ' | ' | ' | ' | ' | ' | ' | ' | ' | -31,148 |
Ending balance, Value at Dec. 31, 2013 | $66,976 | ' | ' | ' | ' | ' | ' | ' | $23 | $162,021 | ($95,068) |
Ending balance, Shares at Dec. 31, 2013 | ' | ' | ' | ' | ' | ' | ' | ' | 23,285,549 | ' | ' |