Aldeyra Therapeutics (ALDX) 10-Q7 Aug 142014 Q2 Quarterly reportFinancial data

Company Profile

Document_and_Entity_Informatio

Document and Entity Information	6 Months Ended
Document and Entity Information	Jun. 30, 2014	Aug. 06, 2014
Document And Entity Information [Abstract]	'	'
Document Type	'10-Q	'
Amendment Flag	'false	'
Document Period End Date	30-Jun-14	'
Document Fiscal Year Focus	'2014	'
Document Fiscal Period Focus	'Q2	'
Entity Registrant Name	'ALDEYRA THERAPEUTICS, INC.	'
Entity Central Index Key	'0001341235	'
Current Fiscal Year End Date	'--12-31	'
Entity Filer Category	'Smaller Reporting Company	'
Entity Common Stock, Shares Outstanding	'	5,565,415

Balance_Sheets_Unaudited

Balance Sheets (Unaudited) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Current assets:	'	'
Cash and cash equivalents	$11,535,788	$3,262,354
Prepaid expenses and other current assets	269,541	8,412
Total current assets	11,805,329	3,270,766
Deferred offering costs	0	472,467
Total assets	11,805,329	3,743,233
Current liabilities:	'	'
Accounts payable	556,061	341,853
Convertible notes payable - related parties	0	85,000
Accrued interest on convertible notes payable - related parties	0	2,125
Accrued expenses	211,346	117,873
Current portion of credit facility	407,120	58,160
Total current liabilities	1,174,527	605,011
Credit facility, net of current portion and debt discount	815,825	1,129,015
Accrued deferred offering costs	0	394,368
Convertible preferred stock warrant liability	0	253,247
Convertible preferred stock warrant liabilities - related parties	0	3,265,620
Total liabilities	1,990,352	5,647,261
Commitments and contingencies	'	'
Redeemable convertible preferred stock:	'	'
Redeemable convertible preferred stock	0	38,317,298
Stockholders' equity (deficit):	'	'
Preferred stock, value	0	0
Additional paid-in capital	51,867,123	1,102,685
Accumulated deficit	-42,057,711	-41,324,338
Total stockholders' equity (deficit)	9,814,977	-40,221,326
Total liabilities, redeemable convertible preferred stock and stockholders' equity (deficit)	11,805,329	3,743,233
Series A Preferred Stock [Member]	'	'
Redeemable convertible preferred stock:	'	'
Redeemable convertible preferred stock	0	29,291,865
Stockholders' equity (deficit):	'	'
Total stockholders' equity (deficit)	'	29,291,865
Series B Preferred Stock [Member]	'	'
Redeemable convertible preferred stock:	'	'
Redeemable convertible preferred stock	0	9,025,433
Stockholders' equity (deficit):	'	'
Total stockholders' equity (deficit)	'	9,025,433
Common stock, voting [Member]	'	'
Stockholders' equity (deficit):	'	'
Common stock, value	5,565	327
Common stock, non-voting [Member]	'	'
Stockholders' equity (deficit):	'	'
Common stock, value	$0	$0

Balance_Sheets_Unaudited_Paren

Balance Sheets (Unaudited) (Parenthetical) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Preferred Stock, par value	$0.00	$0.00
Preferred Stock, shares authorized	15,000,000	0
Preferred Stock, shares issued	0	0
Preferred Stock, shares outstanding	0	0
Series A Preferred Stock [Member]	'	'
Preferred Stock, par value	$0.00	$0.00
Preferred Stock, shares authorized	0	24,000,000
Preferred Stock, shares issued	0	980,391
Preferred Stock, shares outstanding	0	980,391
Preferred Stock, Liquidation preference	$0	$36,000,000
Series B Preferred Stock [Member]	'	'
Preferred Stock, par value	$0.00	$0.00
Preferred Stock, shares authorized	0	38,000,000
Preferred Stock, shares issued	0	1,316,681
Preferred Stock, shares outstanding	0	1,316,681
Preferred Stock, Liquidation preference	$0	$20,377,506
Common stock, voting [Member]	'	'
Common stock, par value	$0.00	$0.00
Common stock, shares authorized	150,000,000	65,000,000
Common stock, shares issued	5,565,415	327,365
Common stock, shares outstanding	5,565,415	327,365
Common stock, non-voting [Member]	'	'
Common stock, par value	$0.00	$0.00
Common stock, shares authorized	0	65,000,000
Common stock, shares issued	0	0
Common stock, shares outstanding	0	0

Statements_of_Operations_and_C

Statements of Operations and Comprehensive Loss (Unaudited) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
OPERATING EXPENSES:	'	'	'	'
Research and development	$663,908	$325,050	$1,108,186	$475,283
General and administrative	982,579	660,640	1,783,225	801,945
Loss from operations	-1,646,487	-985,690	-2,891,411	-1,277,228
OTHER INCOME (EXPENSE):	'	'	'	'
Change in fair value of preferred stock warrant liabilities	567,588	-36,100	2,327,502	-313,600
Change in fair value of convertible preferred stock rights and rights option liabilities	'	-531,700	'	-3,922,200
Interest income	'	8	3	16
Interest expense	-56,246	-15,301	-169,467	-30,705
Total other income (expense), net	511,342	-583,093	2,158,038	-4,266,489
Net loss and comprehensive loss	-1,135,145	-1,568,783	-733,373	-5,543,717
Accretion of preferred stock	-141,513	-150,095	-333,082	-273,254
Deemed dividend	-4,053,570	'	-4,053,570	'
Net loss attributable to common stockholders	($5,330,228)	($1,718,878)	($5,120,025)	($5,816,971)
Net loss per share attributable to common stockholders:	'	'	'	'
Basic	($1.43)	($5.47)	($2.51)	($18.50)
Diluted	($1.56)	($5.47)	($3.53)	($18.50)
Weighted average common shares outstanding:	'	'	'	'
Basic	3,737,675	314,419	2,041,941	314,419
Diluted	3,769,360	314,419	2,107,389	314,419

Statements_of_Redeemable_Conve

Statements of Redeemable Convertible Preferred Stock and Stockholders' Equity (Deficit) (Unaudited) (USD $)	Total	Series A Preferred Stock [Member]	Series B Preferred Stock [Member]	Redeemable Convertible Preferred Stock [Member]	Common stock, voting [Member]	Additional Paid-in Capital [Member]	Deficit Accumulated During the Development Stage [Member]
Beginning Balance at Dec. 31, 2013	($40,221,326)	$29,291,865	$9,025,433	$38,317,298	$327	$1,102,685	($41,324,338)
Beginning Balance, Shares at Dec. 31, 2013	'	980,391	1,316,681	'	327,365	'	'
Stock-based compensation expense	1,114,107	'	'	'	'	1,114,107	'
Accretion of discounts and issuance costs on preferred stock	-333,082	78,037	255,045	333,082	'	-333,082	'
Issuance of common stock, net of issuance costs	9,976,908	'	'	'	1,500	9,975,408	'
Issuance of Common stock, net of costs, Shares	'	'	'	'	1,500,000	'	'
Conversion of Preferred	38,650,379	-29,369,902	-9,280,478	-38,650,380	3,643	38,646,736	'
Conversion of Preferred, Shares	'	-980,391	-1,316,681	'	3,642,799	'	'
Net exercise of warrants	1,191,364	'	'	'	74	1,191,290	'
Net exercise of warrants, Shares	'	'	'	'	74,001	'	'
Conversion feature on convertible promissory note	170,000	'	'	'	21	169,979	'
Conversion feature on convertible promissory note, Shares	'	'	'	'	21,250	'	'
Net loss	-733,373	'	'	'	'	'	-733,373
Ending Balance at Jun. 30, 2014	$9,814,977	'	'	'	$5,565	$51,867,123	($42,057,711)
Ending Balance, Shares at Jun. 30, 2014	'	'	'	'	5,565,415	'	'

Statements_of_Cash_Flows_Unaud

Statements of Cash Flows (Unaudited) (USD $)	6 Months Ended
Statements of Cash Flows (Unaudited) (USD $)	Jun. 30, 2014	Jun. 30, 2013
CASH FLOWS FROM OPERATING ACTIVITIES:	'	'
Net loss	($733,373)	($5,543,717)
Adjustments to reconcile net loss to net cash used in operating activities:	'	'
Stock-based compensation	1,114,107	674,824
President and CEO contributed services	'	120,000
Amortization of debt discount - non-cash interest expense	120,770	14,670
Change in fair value of warrant liability, purchase rights and warrant purchase rights	-2,327,502	4,235,800
Change in operating assets and liabilities: (Increase) decrease	'	'
Prepaid expenses and other current assets	-261,129	-4,923
Accounts payable	37,433	-46,916
Accrued interest on convertible notes payable-related parties	-2,125	'
Accrued expenses	93,473	-38,504
Net cash used in operating activities	-1,958,346	-588,766
CASH FLOWS FROM FINANCING ACTIVITIES:	'	'
Principal payments on notes	'	-41,667
Net proceeds from issuance of common stock	10,231,780	'
Net proceeds from issuance of Series B redeemable convertible preferred stock	'	750,436
Net cash provided by financing activities	10,231,780	708,769
NET INCREASE IN CASH	8,273,434	120,003
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	3,262,354	1,223,638
CASH AND CASH EQUIVALENTS, END OF PERIOD	11,535,788	1,343,641
Cash paid during the period for:	'	'
Interest	51,579	16,318
Income taxes	0	0
SUPPLEMENTAL DISCLOSURES OF NON CASH INVESTING AND FINANCING ACTIVITIES:	'	'
Accretion of redeemable convertible preferred stock	333,082	273,255
Conversion of notes payable	170,000	'
Conversion of Series A preferred stock upon closing initial public offering	-38,650,379	'
Net exercise of warrants into common stock	1,191,365	'
Offering costs of initial public offering not yet paid	176,775	'
Warrants issued to underwriter in initial public offering	315,388	'
Series A Preferred Stock [Member]	'	'
SUPPLEMENTAL DISCLOSURES OF NON CASH INVESTING AND FINANCING ACTIVITIES:	'	'
Conversion of Series A preferred stock upon closing initial public offering	29,369,902	'
Series B Preferred Stock [Member]	'	'
SUPPLEMENTAL DISCLOSURES OF NON CASH INVESTING AND FINANCING ACTIVITIES:	'	'
Conversion of Series A preferred stock upon closing initial public offering	$9,280,478	'

Nature_of_Business

Nature of Business	6 Months Ended
	Jun. 30, 2014
Accounting Policies [Abstract]	'
Nature of Business	'
	1	NATURE OF BUSINESS
	Aldeyra Therapeutics, Inc. (the Company) was incorporated in the state of Delaware on August 13, 2004 as Neuron Systems, Inc. On December 20, 2012, the Company changed its name to Aldexa Therapeutics, Inc. and on March 17, 2014, the Company changed its name to Aldeyra Therapeutics, Inc. The Company is developing a treatment for diseases thought to be related to high levels of free aldehydes, naturally occurring pro-inflammatory toxins.
	The Company’s principal activities to date include raising capital and research and development activities.

Basis_of_Presentation

Basis of Presentation	6 Months Ended
	Jun. 30, 2014
Accounting Policies [Abstract]	'
Basis of Presentation	'
	2	BASIS OF PRESENTATION
	The accompanying interim unaudited financial statements and related disclosures are unaudited and have been prepared in accordance with U.S. generally accepted accounting principles (GAAP) for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all the information and footnotes required by GAAP for complete financial statements and should be read in conjunction with the Company’s financial statements for the year ended December 31, 2013 included in the Company’s Registration Statement on Form S-1, as amended (File No. 333-193204) (Registration Statement), which was declared effective by the Securities and Exchange Commission (SEC) on May 1, 2014. The financial information as of June 30, 2014, the three and six months ended June 30, 2014 and 2013 is unaudited but, in the opinion of management, all adjustments, consisting only of normal recurring accruals, considered necessary for a fair statement of the results of these interim periods have been included. The balance sheet data as of December 31, 2013 was derived from audited financial statements. The results of the Company’s operations for any interim period are not necessarily indicative of the results that may be expected for any other interim period or for a full fiscal year.
	The Company’s initial public offering of common stock (Initial Public Offering) was completed on May 7, 2014.
	Use of estimates
	The preparation of financial statements in conformity with GAAP requires management to make estimates that affect the reported amounts of assets and liabilities at the date of the financial statements, disclosure of contingent assets and liabilities, and the reported amounts of revenue and expenses during the reporting period. Actual results could differ from those estimates.
	Reverse stock split
	On January 23, 2014, the Company’s board of directors and stockholders approved an amendment to the restated certificate of incorporation to effect a one-for-twelve reverse stock split of the Company’s common stock, options for common stock, convertible preferred stock, and warrants for convertible preferred stock which became effective on May 1, 2014, prior to the effectiveness of the Registration Statement (the Reverse Stock Split). The par value and the authorized shares of the common and convertible preferred stock were not adjusted as a result of the Reverse Stock Split. All issued and outstanding common stock, options for common stock, convertible preferred stock, and rights and warrants for convertible preferred stock, as well as the exercise price of each option for common stock, each right and each warrant for convertible preferred stock, and each right for warrants for convertible preferred stock and the conversion price for convertible preferred stock, have been retroactively adjusted to reflect this Reverse Stock Split for all periods presented. All of the share and per share amounts have been adjusted, on a retroactive basis, to reflect the Reverse Stock Split.
	New accounting pronouncements
	Accounting Standards Update (“ASU”) No. 2014-10 – Development Stage Entities (Topic 915); Elimination of Certain Financial Reporting Requirements, Including an Amendment to Variable Interest Entities, Guidance in Topic 810, Consolidation. The Financial Accounting Standards Board decided to remove the definition of development stage entity from the Master Glossary of the Accounting Standards Codification on the basis of the effects of its decisions to eliminate any special reporting requirements by development stage entities. For public business entities, the changes are effective for annual reporting periods beginning after December 15, 2014, and interim reporting periods therein. Entities are allowed to apply such guidance early for any annual reporting period or interim period for which the entity’s financial statements have not yet been issued. The Company adopted ASU No. 2014-10 during the three months ended June 30, 2014. The adoption of ASU No. 2014-10, did not have a material effect on the Company’s financial statements other than the elimination of inception-to-date reporting information in accordance with the provisions of ASU 2014-10. Prior to our adoption ASU 2014-10, we were considered in the development stage in accordance with existing generally accepted accounting principles.

	In May 2014, the FASB issued Accounting Standards Update No. 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”). The amendments in ASU 2014-09 provide for a single, principles-based model for revenue recognition that replaces the existing revenue recognition guidance. ASU 2014-09 is effective for annual and interim periods beginning on or after December 15, 2016 and will replace most existing revenue recognition guidance under U.S. GAAP when it becomes effective. It permits the use of either a retrospective or cumulative effect transition method and early adoption is not permitted. As the Company has not generated revenues the Company has not yet selected a transition method and is in the process of evaluating the effect this standard will have on our financial statements and related disclosures.

Net_Loss_Attributable_to_Commo

Net Loss Attributable to Common Stockholders	6 Months Ended
Net Loss Attributable to Common Stockholders	Jun. 30, 2014
Earnings Per Share [Abstract]	'
Net Loss Attributable to Common Stockholders	'
	3	NET LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS
	Net loss attributable to common stockholders
	The following table summarizes the computation of basic and diluted net loss per share attributable to common stockholders of the Company:


		Three Months Ended June 30,						Six Months Ended June 30,
		2014			2013			2014			2013
	Numerator:
	Basic
	Net loss and comprehensive loss	$	(1,135,145	)	$	(1,568,783	)	$	(733,373	)	$	(5,543,717	)
	Accretion of preferred stock		(141,513	)		(150,095	)		(333,082	)		(273,254	)
	Deemed dividend		(4,053,570	)		—			(4,053,570	)		—

	Net loss attributable to common stockholders – basic	$	(5,330,228	)	$	(1,718,878	)	$	(5,120,025	)	$	(5,816,971	)

	Diluted
	Net loss attributable to common stockholders – basic	$	(5,330,228	)	$	(1,718,878	)		(5,120,025	)		(5,816,971	)
	Less: change in fair value of derivative liabilities		(567,588	)		—			(2,327,502	)		—

	Net loss available to common stockholders – diluted	$	(5,897,816	)	$	(1,718,878	)	$	(7,447,527	)	$	(5,816,971	)

	Denominator:
	Basic
	Weighted-average number of common shares – basic		3,737,675			314,419			2,041,941			314,419

	Diluted
	Weighted-average number of common shares – basic		3,737,675			314,419			2,041,941			314,419
	Warrants (treasury stock)		31,685			—			65,448			—

	Total weighted average number of common shares – diluted		3,769,360			314,419			2,107,389			314,419

	Net loss per share:
	Basic	$	(1.43	)	$	(5.47	)	$	(2.51	)	$	(18.50	)

	Diluted	$	(1.56	)	$	(5.47	)	$	(3.53	)	$	(18.50	)


	Because the Company reported a net loss for the three and six months ended June 30, 2013, diluted net loss per common share is the same as basic net loss per common share for that period.
	The following potentially dilutive securities outstanding, prior to use of the treasury stock method or if-converted method, have been excluded from the computation of diluted weighted-average shares outstanding, because such securities had an antidilutive impact due to losses reported:


		Three Months Ended June 30,						Six Months Ended June 30,
		2014			2013			2014			2013
	Options to purchase stock		87,241			67,232			87,258			67,232
	Warrants to purchase Preferred Stock		—			67,376			—			65,439
	Preferred Stock		1,240,955			3,642,799			2,435,245			3,642,799
	Convertible note payable-related parties		8,640			—			14,910			—
	Rights to receive warrants for Preferred Stock		—			160,160			—			157,803
	Investor rights to purchase Preferred Stock		—			640,638			—			631,211

	Total of common equivalent shares		1,336,836			4,578,205			2,537,413			4,564,484

Fair_Value_Measurements

Fair Value Measurements	6 Months Ended
Fair Value Measurements	Jun. 30, 2014
Fair Value Disclosures [Abstract]	'
Fair Value Measurements	'
	4	FAIR VALUE MEASUREMENTS
	As of June 30, 2014 and December 31, 2013, the carrying amounts of cash and cash equivalents, prepaid expenses and other current assets, and accounts payable approximated their estimated fair values because of the short term nature of these financial instruments. The carrying value of the Company’s credit facility and convertible notes – related parties in current and long-term liabilities approximates fair value because the Company’s interest rate yield is near current market rates available to the Company.
	Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value are performed in a manner to maximize the use of observable inputs and minimize the use of unobservable inputs. ASC 820, Fair Value Measurements, establishes a fair value hierarchy based on three levels of inputs, of which the first two are considered observable and the last unobservable, that may be used to measure fair value, which are the following:
	Level 1 – Quoted prices in active markets that are accessible at the market date for identical unrestricted assets or liabilities.
	Level 2 – Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs for which all significant inputs are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
	Level 3 – Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

	There were no liabilities measured at fair value at June 30, 2014. Liabilities measured at fair value on a recurring basis as of December 31, 2013 are as follows:


		Level 1			Level 2			Level 3		Total
	December 31, 2013:
	Liabilities:
	Preferred Stock Warrant Liability – Series B Preferred Stock	$	—		$	—		$	3,439,059	$	3,439,059
	Preferred Stock Warrant Liability – Series A Preferred Stock		—			—			79,808		79,808

	Balance at end of period	$	—		$	—		$	3,518,867	$	3,518,867

	The reconciliation of the Company’s liabilities measured at fair value on a recurring basis using unobservable inputs (Level 3) is as follows:
	Preferred stock warrant liability – Series A Preferred Stock:


		Period Ended			Year Ended
		June 30,			December 31, 2013
		2014
	Balance at beginning of period	$	79,808		$	87,600
	Net exercise of Series A Warrants		(29,247	)		—
	Change in fair value		(50,561	)		(7,792	)

	Balance at end of period	$	—		$	79,808

	Preferred stock warrant liability – Series B Preferred Stock:


		Period Ended			Year Ended
		30-Jun-14			December 31, 2013
	Balance at beginning of period	$	3,439,059		$	2,180,500
	Net exercise of Series B Warrants		(1,162,118	)		—
	Exercise of warrants purchase rights into Series B Warrants		—			1,793,600
	Warrant liability – Series B		—			177,952
	Change in fair value		(2,276,941	)		(712,993	)

	Balance at end of period	$	—		$	3,439,059

	The Company’s preferred stock warrant liabilities were classified as level 3 and valued using the Black-Scholes model. The fair values were derived by applying the assumptions described below. These liabilities increased or decreased each period based on the fluctuations of the fair value of the underlying preferred security.

	The table below shows the inputs used by instrument to determine the fair value measurements at December 31, 2013:


		December 31,
		2013
	Preferred stock warrant liability – Series A
	Expected dividend yield		0	%
	Anticipated volatility		88.57	%
	Estimated stock price	$	45.2
	Exercise price	$	12.24
	Expected life (years)		5.28
	Risk free interest rate		1.75	%
	Preferred stock warrant liabilities – Series B
	Expected dividend yield		0	%
	Anticipated volatility		88.57	%
	Estimated stock price	$	19.92
	Exercise price	$	5.16
Expected life (years)		3.97 – 6.89
Risk free interest rate		0.78% – 2.45	%

Convertible_Notes_Payable_Rela

Convertible Notes Payable - Related Parties	6 Months Ended
	Jun. 30, 2014
Text Block [Abstract]	'
Convertible Notes Payable - Related Parties	'
	5	CONVERTIBLE NOTES PAYABLE – RELATED PARTIES
	In October 2013, the Company issued a convertible promissory note to Domain Partners VI, L.P., a related party, in a principal amount of $170,000, which was amended in February 2014 to extend its maturity date. The amendment to the note was determined to be a modification in accordance with ASC 470, Debt, and did not result in extinguishment. The note accrued interest at a rate of 6% per annum, and was to become due and payable in June 2014 unless converted into shares of the Company’s capital stock prior to such time pursuant to its terms.
	The Company recorded the difference between the current Series B Preferred Stock Conversion price and the fair value of the Series B Preferred Stock at the date of issuance, limited to the face amount of the convertible promissory note of $170,000, as a beneficial conversion feature. This is reflected as a debt discount and is being amortized to interest expense through the note’s maturity date.
	Upon the Company’s Initial Public Offering in May 2014, the note automatically converted into 21,250 shares of the Company’s common stock.

Credit_Facility

Credit Facility	6 Months Ended
	Jun. 30, 2014
Debt Disclosure [Abstract]	'
Credit Facility	'
	6	CREDIT FACILITY
	On April 12, 2012, the Company entered into a loan and security agreement (Credit Facility) with a bank with availability in the amount of $500,000, to provide additional capital for general working capital purposes and for capital expenditures. Interest accrued from the date of each advance equal to the greater of (a) 2.75% above the prime rate then in effect per annum, or (b) 6.50% per annum. Any amounts outstanding were payable in 24 equal monthly installments of principal, plus all accrued interest, beginning on May 12, 2013 until the loan maturity date of April 13, 2015. There were no penalties for prepayment of the principal balance. The Credit Facility was subject to certain financial covenants. The interest rate since inception of this loan has been in accordance with (b) above, 6.50%. In conjunction with obtaining the Credit Facility, the Company issued a warrant to purchase for 2,042 shares of Series A Preferred Stock. The warrant was valued at $88,100 on the date of issuance and recorded as a discount on the Credit Facility and is being amortized using the effective interest method through the maturity date of the Credit Facility.
	During 2012, the Company received two advance payments totaling $500,000, the maximum borrowings under the Credit Facility. In accordance with this agreement, the Company was only required to make monthly interest payments until April 12, 2013, at which time the Company was to begin making monthly principal payments in a fixed amount of $20,833 plus interest.
	On November 20, 2013, the Company amended its Credit Facility with the same bank. The amendment provided an additional $1.0 million of available funds under the facility. The Company received an advance payment of $1.0 million in November 2013 through a term loan. The amended Credit Facility calls for interest only payments at a 6.50% interest rate per annum from November 2013 through November 2014 for all amounts outstanding, inclusive of those amounts originally drawn during 2012 prior to the amendment, at which point, the Company is required to make principal payments of $58,160 plus interest through the maturity date of the term loans in November 2016. The Credit Facility, as amended, may have financial covenants established at a future date.
	Both the original Credit Facility and the Credit Facility, as amended, are secured by all the intellectual property of the Company.
	In conjunction with obtaining the amended Credit Facility, the Company issued a warrant exercisable for 9,692 shares of Series B Preferred Stock with an exercise price of $5.16 per share and a term of seven years. The warrant was valued at $177,952 and, together with the fair value of the warrant issued in connection with the original Credit Facility ($88,100), was recorded as a discount on the Credit Facility. These discounts are being amortized using the effective interest method through the current maturity date of the Credit Facility in November 2016. The amendment to the Credit Facility was determined to be a modification in accordance with ASC 470, Debt, and did not result in extinguishment.
	At June 30, 2014, the Credit Facility is shown net of a debt discount of $172,889 which is being amortized using the effective interest method through the maturity date of the Credit Facility.

Income_Taxes

Income Taxes	6 Months Ended
	Jun. 30, 2014
Income Tax Disclosure [Abstract]	'
Income Taxes	'
	7	INCOME TAXES
	No provision for federal taxes has been recorded as the Company has incurred losses since inception for tax purposes. Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes.
	In assessing the realizability of net deferred taxes in accordance with ASC 740, Income Taxes, the Company considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. Based on the weight of available evidence, primarily the incurrence of net losses since inception and anticipated net losses in the near future, the Company does not consider it more likely than not that some or all of the net deferred taxes will be realized. Accordingly, a 100% valuation allowance has been applied against net deferred taxes.
	Under the provisions of the Internal Revenue Code, certain substantial changes in the Company’s ownership may result in a limitation on the amount of net operating loss carryforwards which can be used in future years.
	All tax years are open for examination by the taxing authorities for both federal and state purposes.
	The Company accounts for uncertain tax positions pursuant to ASC 740 which prescribes a recognition threshold and measurement process for financial statement recognition of uncertain tax positions taken or expected to be taken in a tax return. If the tax position meets this threshold, the benefit to be recognized is measured as the tax benefit having the highest likelihood of being realized upon ultimate settlement with the taxing authority. The Company recognizes interest accrued related to unrecognized tax benefits and penalties in the provision for income taxes. Management is not aware of any uncertain tax positions.

Stock_Incentive_Plan

Stock Incentive Plan

6 Months Ended

Jun. 30, 2014

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Stock Incentive Plan

STOCK INCENTIVE PLAN

The Company has three incentive plans. One was adopted in 2004 (2004 Plan) and provided for the granting of stock options and restricted stock awards to employees, board members and consultants and generally prescribed a contractual term of seven years. The 2004 Plan terminated in August 2010. However, grants made under the 2004 Plan are still governed by that plan. As of June 30, 2014, options to purchase 23,954 shares of common stock at an exercise price of $3.24 per share remained outstanding under the 2004 Plan.

The Company approved the 2010 Employee, Director and Consultant Equity Incentive Plan (2010 Plan) in September 2010 to replace the 2004 Plan. The 2010 Plan provided for the granting of stock options and restricted stock awards to certain employees, members of the board of directors and consultants of the Company. As of June 30, 2014, the number of shares of common stock authorized for issuance in connection with the 2010 Plan was 681,788. As of June 30, 2014, there were no shares available for issuance under the 2010 Plan.

The 2010 Plan terminated upon the Initial Public Offering. However, grants made under the 2010 Plan are still governed by that plan.

The Company approved the 2013 Equity Incentive Plan (2013 Plan) in October 2013. The 2013 Plan became effective immediately on adoption although no awards were to be made under it until the effective date of the Registration Statement for the Initial Public Offering. The 2013 Plan provides for the granting of stock options, restricted stock, stock appreciation rights, stock units, and performance cash awards to certain employees, members of the board of directors and consultants of the Company. As of June 30, 2014, the number of shares of common stock authorized for issuance in connection with the 2013 Plan was 625,000. As of the first business day of each fiscal year of the Company during the term of the Plan, commencing on the first day of the Company’s 2015 fiscal year, the aggregate number of common shares that may be issued under the Plan shall automatically increase by a number equal to the least of (a) 4% of the total number of common shares outstanding on the last calendar day of the prior fiscal year, (b) subject to adjustment for certain corporate transactions, 333,333 common shares, or (c) a number of common shares determined by the Company’s board of directors. As of June 30, 2014, there were 469,852 shares available for issuance under the 2013 Plan.

Options granted for the year ended December 31, 2013 include two grants of options exercisable for a total of 32,014 common shares for which vesting is contingent on certain performance conditions. For options granted containing performance conditions, the fair value is determined on the date of grant. For the three and six months ended June 30, 2014, there was $340,372 expense recorded relating to the options as the performance conditions were satisfied in May 2014.

There were stock options outstanding to purchase an aggregate of 764,990 shares of common stock at June 30, 2014 with a weighted average exercise price per share of $2.80 and stock options to purchase an aggregate of 609,842 shares of common stock outstanding at December 31, 2013 with a weighted average exercise price per share of $1.48. There were stock options to purchase an aggregate of 155,148 shares of common stock granted during the three months ended June 30, 2014 with an average exercise price per share of $8.00. The following table summarizes information about stock options exercisable at June 30, 2014:

Period Ending

Number

Outstanding

Exercisable

Weighted-

Average

Remaining

Contractual

Life

June 30, 2014

115,622

9.12

7.8

The Company has also issued stock options to non-employees at various grant dates from inception. In determining the expense associated with their vesting, those non-employee stock options were valued using the Black-Scholes option-pricing model using the fair value of the common stock and the following assumptions:

June 30, 2014

Expected dividend yield

Anticipated volatility

88.57

Estimated stock price

6.56

Exercise price

0.552

Expected life (years)

9.195

Risk free interest rate

2.4

There were no options granted to consultants during the six month period ended June 30, 2014. The stock-based compensation is subject to remeasurement and is being expensed over the related service term.

Stock-based compensation is recognized for stock options granted to employees and non-employees and has been reported in the Company’s statement of operations as follows:

Three Months Ended

Six Months Ended

30-Jun-14

30-Jun-13

30-Jun-14

30-Jun-13

Research and development expenses

203,474

156,846

282,000

206,165

General and administrative expenses

544,948

467,531

832,107

468,659

Total stock-based compensation expense

748,422

624,377

1,114,107

674,824

Contributed_Services

Contributed Services	6 Months Ended
	Jun. 30, 2014
Compensation And Retirement Disclosure [Abstract]	'
Contributed Services	'
	9	CONTRIBUTED SERVICES
	The Company’s President and Chief Executive Officer (CEO) was hired on January 6, 2012 on a half-time basis and on April 15, 2013, he began working full-time for the Company. During the period from January 6, 2012 through October 14, 2013, he was not paid a salary by the Company and was an employee and paid a salary by Domain
	Associates, LLC (Domain), a related party. The value of his services has been reflected in the statement of operations as an expense and recorded as a contribution of capital. For the three and six month period ended June 30, 2013, the value of his services was $78,000 and $120,000, respectively. There were no contributed services for the three or six month period ended June 30, 2014.

Redeemable_Convertible_Preferr

Redeemable Convertible Preferred Stock	6 Months Ended
	Jun. 30, 2014
Equity [Abstract]	'
Redeemable Convertible Preferred Stock	'
	10	REDEEMABLE CONVERTIBLE PREFERRED STOCK
	Series A Preferred Stock and Series B Preferred Stock
	On May 7, 2014, the Company closed its Initial Public Offering, in which 1,500,000 shares of common stock were sold at a price to the public of $8.00 per share for an aggregate offering price of $12.0 million. The offer and sale of all of the shares in the Initial Public Offering were registered under the Securities Act of the 1933, as amended, pursuant to a registration statement on Form S-1 (File No. 333-193204), which was declared effective by the SEC on May 1, 2014. The offering commenced as of May 1, 2014 and did not terminate before all of the securities registered in the registration statement were sold. Aegis Capital Corp. acted as the sole manager of the offering and as representative of the underwriters. The Company raised approximately $10 million in net proceeds after deducting underwriting discounts and commissions of $0.8 million, $1.0 million in prepaid offering and printing costs and other offering costs of $0.2 million.
	In connection with the Initial Public Offering, holders of at least 67% of the respective outstanding Series A and Series B Preferred Stock (Series A and Series B voting as separate single classes) elected to automatically convert the Series A Preferred Stock and Series B Preferred Stock into 3,642,800 shares of common stock. The remaining unamortized discount was considered a deemed dividend for the three and six month periods ended June 30, 2014.

Stock_Purchase_Warrants

Stock Purchase Warrants	6 Months Ended
	Jun. 30, 2014
Text Block [Abstract]	'
Stock Purchase Warrants	'
	11	STOCK PURCHASE WARRANTS
	On April 12, 2012, in connection with the signing of the Credit Facility agreement, the Company granted warrants to purchase 2,042 shares of Series A Preferred Stock (Series A Warrants) at an exercise price of $12.24 per share to Square 1 Bank.
	On December 20, 2012, in connection with the sale and issuance of Series B Preferred Stock on that date, the Company granted warrants to purchase 96,921 shares of Series B Preferred Stock at an exercise price of $5.16 per share to the Series B Preferred Stock investors.
	On August 14, 2013, in connection with the sale and issuance of Series B Preferred Stock on that date, the Company granted warrants to purchase 96,921 shares of Series B Preferred Stock at an exercise price of $5.16 per share to the Series B Preferred Stock investors.
	On November 20, 2013, the Company granted a warrant exercisable for 9,692 shares of Series B Preferred Stock to Square 1 Bank in connection with the amendment to the Credit Facility. The warrant has an exercise price of $5.16.
	In connection with the Initial Public Offering, the holders of the outstanding Series A and Series B Preferred Stock Warrants elected to net exercise the warrants and the shares of Series A Preferred Stock and Series B Preferred Stock issued upon such net exercise were automatically converted into 74,001 shares of common stock.
	Also in connection with the Initial Public Offering, the Company issued the underwriters of the offering warrants to purchase up to 60,000 shares of common stock. The warrants are exercisable beginning on May 1, 2015 for cash or on a cashless basis at a per share price of $10.00. The warrants will expire on May 1, 2019

Related_Party_Transactions

Related Party Transactions	6 Months Ended
	Jun. 30, 2014
Related Party Transactions [Abstract]	'
Related Party Transactions	'
	12	RELATED PARTY TRANSACTIONS
	In November 2013, the Company entered into a letter agreement with each of its CEO and Chief Operating Officer (COO) that became effective on the effective date of the Initial Public Offering. The letter agreements were subsequently amended in February 2014. Pursuant to these letter agreements, if the Company terminates the employment of its CEO or COO without cause or if such executive resigns for good reason, then he will be eligible to receive: continued payment of base salary for 12 months; a lump-sum cash payment equal to the greater of such executive’s target bonus for the year in which such termination occurs or the actual bonus paid to the executive with respect to our most recently completed fiscal year; payment by the Company of the monthly premiums under COBRA for such executive and their eligible dependents for up to 12 months following the termination of such executive’s employment; and accelerated vesting and exercisability with respect to all equity or equity-based awards held by such executive officer as if such executive officer has completed an additional 12 months of service with the Company, and up to 12 months following such termination to exercise any then-outstanding stock options or stock appreciation rights. Such payments are contingent on the officer’s executing and not revoking a release of claims against the Company. As of June 30, 2014 and December 31, 2013, the Company assessed the likelihood for these events to occur and has determined that a liability related to these agreements is not likely to occur and therefore has not been recorded.
	In June 2014, the Company entered into a letter agreement with its CFO. Pursuant to the letter agreements, if the Company terminates the employment of its CFO without cause or if such executive resigns for good reason, then he will be eligible to receive: continued payment of base salary for 9 months; a lump-sum cash payment equal to the greater of such executive’s target bonus for the year in which such termination occurs or the actual bonus paid to the executive with respect to our most recently completed fiscal year; payment by the Company of the monthly premiums under COBRA for such executive and their eligible dependents for up to 9 months following the termination of such executive’s employment; and accelerated vesting and exercisability with respect to all equity or equity-based awards held by such executive officer as if such executive officer has completed an additional 12 months of service with the Company, and up to 12 months following such termination to exercise any then-outstanding stock options or stock appreciation rights. Such payments are contingent on the officer’s executing and not revoking a release of claims against the Company. As of June 30, 2014, the Company assessed the likelihood for these events to occur and has determined that a liability related to these agreements is not likely to occur and therefore has not been recorded.

	Convertible Promissory Note – In October 2013, the Company issued a convertible promissory note to Domain Partners VI, L.P., in a principal amount of $170,000, which was amended in February 2014 to extend its maturity date.
	The note accrued interest at a rate of 6% per annum, and would have become due and payable in June 2014 unless it converted into shares of the Company’s capital stock prior to such time pursuant to its terms.
	Upon the Company’s Initial Public Offering in May 2014, the note automatically converted into 21,250 shares of the Company’s common stock.

Commitments_and_Contingencies

Commitments and Contingencies	6 Months Ended
	Jun. 30, 2014
Commitments And Contingencies Disclosure [Abstract]	'
Commitments and Contingencies	'
	13	COMMITMENTS AND CONTINGENCIES
	Guarantees and Indemnifications – As permitted under Delaware law, the Company indemnifies its officers and directors for certain events or occurrences while the officer or director is, or was, serving at the Company’s request in such capacity. The term of the indemnification is for the officer’s or director’s lifetime. Through June 30, 2014, the Company had not experienced any losses related to these indemnification obligations and no material claims were outstanding. The Company does not expect significant claims related to these indemnification obligations, and consequently, concluded that the fair value of these obligations is negligible, and no related reserves were established.
	Other Contractual Arrangements – In February 2010, the Company entered into a license and supply agreement providing the Company with an exclusive license to certain technology and access to purchase materials at certain costs. Under the terms of the license and supply agreement, the Company is obligated to make milestone payments up to an aggregate of $2.15 million upon reaching certain development and regulatory milestones in the development of the Company’s product. Upon commercialization of the Company’s product containing the licensed technology, the Company would be obligated to pay royalties based on net sales subject to an annual cap. The license and supply agreement runs through the 7th anniversary of the expiration of all patents licensed under the agreement, which the Company estimates to be April 2036, unless terminated earlier.

Basis_of_Presentation_Policies

Basis of Presentation (Policies)	6 Months Ended
Basis of Presentation (Policies)	Jun. 30, 2014
Accounting Policies [Abstract]	'
Use of estimates	'
	Use of estimates
	The preparation of financial statements in conformity with GAAP requires management to make estimates that affect the reported amounts of assets and liabilities at the date of the financial statements, disclosure of contingent assets and liabilities, and the reported amounts of revenue and expenses during the reporting period. Actual results could differ from those estimates.
Reverse stock split	'
	Reverse stock split
	On January 23, 2014, the Company’s board of directors and stockholders approved an amendment to the restated certificate of incorporation to effect a one-for-twelve reverse stock split of the Company’s common stock, options for common stock, convertible preferred stock, and warrants for convertible preferred stock which became effective on May 1, 2014, prior to the effectiveness of the Registration Statement (the Reverse Stock Split). The par value and the authorized shares of the common and convertible preferred stock were not adjusted as a result of the Reverse Stock Split. All issued and outstanding common stock, options for common stock, convertible preferred stock, and rights and warrants for convertible preferred stock, as well as the exercise price of each option for common stock, each right and each warrant for convertible preferred stock, and each right for warrants for convertible preferred stock and the conversion price for convertible preferred stock, have been retroactively adjusted to reflect this Reverse Stock Split for all periods presented. All of the share and per share amounts have been adjusted, on a retroactive basis, to reflect the Reverse Stock Split.
New accounting pronouncements	'
	New accounting pronouncements
	Accounting Standards Update (“ASU”) No. 2014-10 – Development Stage Entities (Topic 915); Elimination of Certain Financial Reporting Requirements, Including an Amendment to Variable Interest Entities, Guidance in Topic 810, Consolidation. The Financial Accounting Standards Board decided to remove the definition of development stage entity from the Master Glossary of the Accounting Standards Codification on the basis of the effects of its decisions to eliminate any special reporting requirements by development stage entities. For public business entities, the changes are effective for annual reporting periods beginning after December 15, 2014, and interim reporting periods therein. Entities are allowed to apply such guidance early for any annual reporting period or interim period for which the entity’s financial statements have not yet been issued. The Company adopted ASU No. 2014-10 during the three months ended June 30, 2014. The adoption of ASU No. 2014-10, did not have a material effect on the Company’s financial statements other than the elimination of inception-to-date reporting information in accordance with the provisions of ASU 2014-10. Prior to our adoption ASU 2014-10, we were considered in the development stage in accordance with existing generally accepted accounting principles.

	In May 2014, the FASB issued Accounting Standards Update No. 2014-09, Revenue from Contracts with Customers (“ASU 2014-09”). The amendments in ASU 2014-09 provide for a single, principles-based model for revenue recognition that replaces the existing revenue recognition guidance. ASU 2014-09 is effective for annual and interim periods beginning on or after December 15, 2016 and will replace most existing revenue recognition guidance under U.S. GAAP when it becomes effective. It permits the use of either a retrospective or cumulative effect transition method and early adoption is not permitted. As the Company has not generated revenues the Company has not yet selected a transition method and is in the process of evaluating the effect this standard will have on our financial statements and related disclosures.
Fair Value Measurements	'
	Fair value is defined as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value are performed in a manner to maximize the use of observable inputs and minimize the use of unobservable inputs. ASC 820, Fair Value Measurements, establishes a fair value hierarchy based on three levels of inputs, of which the first two are considered observable and the last unobservable, that may be used to measure fair value, which are the following:
	Level 1 – Quoted prices in active markets that are accessible at the market date for identical unrestricted assets or liabilities.
	Level 2 – Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs for which all significant inputs are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
	Level 3 – Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

Net_Loss_Attributable_to_Commo1

Net Loss Attributable to Common Stockholders (Tables)	6 Months Ended
Net Loss Attributable to Common Stockholders (Tables)	Jun. 30, 2014
Earnings Per Share [Abstract]	'
Computation of Basic and Diluted Net Income (Loss) per Share Attributable to Common Stockholders	'
	The following table summarizes the computation of basic and diluted net loss- per share attributable to common stockholders of the Company:


		Three Months Ended June 30,						Six Months Ended June 30,
		2014			2013			2014			2013
	Numerator:
	Basic
	Net loss and comprehensive loss	$	(1,135,145	)	$	(1,568,783	)	$	(733,373	)	$	(5,543,717	)
	Accretion of preferred stock		(141,513	)		(150,095	)		(333,082	)		(273,254	)
	Deemed dividend		(4,053,570	)		—			(4,053,570	)		—

	Net loss attributable to common stockholders – basic	$	(5,330,228	)	$	(1,718,878	)	$	(5,120,025	)	$	(5,816,971	)

	Diluted
	Net loss attributable to common stockholders – basic	$	(5,330,228	)	$	(1,718,878	)		(5,120,025	)		(5,816,971	)
	Less: change in fair value of derivative liabilities		(567,588	)		—			(2,327,502	)		—

	Net loss available to common stockholders – diluted	$	(5,897,816	)	$	(1,718,878	)	$	(7,447,527	)	$	(5,816,971	)

	Denominator:
	Basic
	Weighted-average number of common shares – basic		3,737,675			314,419			2,041,941			314,419

	Diluted
	Weighted-average number of common shares – basic		3,737,675			314,419			2,041,941			314,419
	Warrants (treasury stock)		31,685			—			65,448			—

	Total weighted average number of common shares – diluted		3,769,360			314,419			2,107,389			314,419

	Net loss per share:
	Basic	$	(1.43	)	$	(5.47	)	$	(2.51	)	$	(18.50	)

	Diluted	$	(1.56	)	$	(5.47	)	$	(3.53	)	$	(18.50	)

Computation of Diluted Weighted-Average Shares Outstanding	'
	The following potentially dilutive securities outstanding, prior to use of the treasury stock method or if-converted method, have been excluded from the computation of diluted weighted-average shares outstanding, because such securities had an antidilutive impact due to losses reported:


		Three Months Ended June 30,						Six Months Ended June 30,
		2014			2013			2014			2013
	Options to purchase stock		87,241			67,232			87,258			67,232
	Warrants to purchase Preferred Stock		—			67,376			—			65,439
	Preferred Stock		1,240,955			3,642,799			2,435,245			3,642,799
	Convertible note payable-related parties		8,640			—			14,910			—
	Rights to receive warrants for Preferred Stock		—			160,160			—			157,803
	Investor rights to purchase Preferred Stock		—			640,638			—			631,211

	Total of common equivalent shares		1,336,836			4,578,205			2,537,413			4,564,484

Fair_Value_Measurements_Tables

Fair Value Measurements (Tables)	6 Months Ended
Fair Value Measurements (Tables)	Jun. 30, 2014
Schedule of Liabilities Measured at Fair Value on Recurring Basis	'
	There were no liabilities measured at fair value at June 30, 2014. Liabilities measured at fair value on a recurring basis as of December 31, 2013 are as follows:


		Level 1			Level 2			Level 3		Total
	December 31, 2013:
	Liabilities:
	Preferred Stock Warrant Liability – Series B Preferred Stock	$	—		$	—		$	3,439,059	$	3,439,059
	Preferred Stock Warrant Liability – Series A Preferred Stock		—			—			79,808		79,808

	Balance at end of period	$	—		$	—		$	3,518,867	$	3,518,867

Schedule of Inputs Used by Instrument to Determine the Fair Value Measurements	'
	The table below shows the inputs used by instrument to determine the fair value measurements at December 31, 2013:


		December 31,
		2013
	Preferred stock warrant liability – Series A
	Expected dividend yield		0	%
	Anticipated volatility		88.57	%
	Estimated stock price	$	45.2
	Exercise price	$	12.24
	Expected life (years)		5.28
	Risk free interest rate		1.75	%
	Preferred stock warrant liabilities – Series B
	Expected dividend yield		0	%
	Anticipated volatility		88.57	%
	Estimated stock price	$	19.92
	Exercise price	$	5.16
	Expected life (years)		3.97 – 6.89
	Risk free interest rate		0.78% – 2.45	%
Level 3 [Member]	'
Schedule of Reconciliation of Liabilities Measured at Fair Value on Recurring Basis	'
	The reconciliation of the Company’s liabilities measured at fair value on a recurring basis using unobservable inputs (Level 3) is as follows:
	Preferred stock warrant liability – Series A Preferred Stock:


		Period Ended			Year Ended
		June 30,			December 31, 2013
		2014
	Balance at beginning of period	$	79,808		$	87,600
	Net exercise of Series A Warrants		(29,247	)		—
	Change in fair value		(50,561	)		(7,792	)

	Balance at end of period	$	—		$	79,808

	Preferred stock warrant liability – Series B Preferred Stock:


		Period Ended			Year Ended
		30-Jun-14			December 31, 2013
	Balance at beginning of period	$	3,439,059		$	2,180,500
	Net exercise of Series B Warrants		(1,162,118	)		—
	Exercise of warrants purchase rights into Series B Warrants		—			1,793,600
	Warrant liability – Series B		—			177,952
	Change in fair value		(2,276,941	)		(712,993	)

	Balance at end of period	$	—		$	3,439,059

Stock_Incentive_Plan_Tables

Stock Incentive Plan (Tables)	6 Months Ended
Stock Incentive Plan (Tables)	Jun. 30, 2014
Summary of Stock Options Exercisable	'
	The following table summarizes information about stock options exercisable at June 30, 2014:


	Period Ending	Number			Outstanding		Exercisable
		Exercisable			Shares		Shares
					Weighted-		Weighted-
					Average		Average
					Remaining		Remaining
					Contractual		Contractual
					Life		Life
	June 30, 2014		115,622			9.12		7.8
Schedule of Stock-Based Compensation Expense	'
	Stock-based compensation is recognized for stock options granted to employees and non-employees and has been reported in the Company’s statement of operations as follows:


		Three Months Ended			Three Months Ended		Six Months Ended		Six Months Ended
		30-Jun-14			30-Jun-13		30-Jun-14		30-Jun-13
	Research and development expenses	$	203,474		$	156,846	$	282,000	$	206,165
	General and administrative expenses		544,948			467,531		832,107		468,659

	Total stock-based compensation expense	$	748,422		$	624,377	$	1,114,107	$	674,824

Non-employee stock options [Member]	'
Schedule of Fair Value of Stock Option Assumptions	'
	In determining the expense associated with their vesting, those non-employee stock options were valued using the Black-Scholes option-pricing model using the fair value of the common stock and the following assumptions:


		June 30, 2014
	Expected dividend yield		0	%
	Anticipated volatility		88.57	%
	Estimated stock price	$	6.56
	Exercise price	$	0.552
	Expected life (years)		9.195
	Risk free interest rate		2.4	%

Basis_of_Presentation_Addition

Basis of Presentation - Additional Information (Detail)	6 Months Ended
Basis of Presentation - Additional Information (Detail)	Jun. 30, 2014
Equity [Abstract]	'
Initial public offering completion date	7-May-14
Reverse stock split ratio	'One-for-twelve

Net_Loss_Attributable_to_Commo2

Net Loss Attributable to Common Stockholders - Computation of Basic and Diluted Net Income (Loss) per Share Attributable to Common Stockholders (Detail) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Basic	'	'	'	'
Net loss and comprehensive loss	($1,135,145)	($1,568,783)	($733,373)	($5,543,717)
Accretion of preferred stock	-141,513	-150,095	-333,082	-273,254
Deemed dividend	-4,053,570	'	-4,053,570	'
Net loss attributable to common stockholders	-5,330,228	-1,718,878	-5,120,025	-5,816,971
Diluted	'	'	'	'
Net loss attributable to common stockholders - basic	-5,330,228	-1,718,878	-5,120,025	-5,816,971
Less: change in fair value of derivative liabilities	-567,588	0	-2,327,502	0
Net loss available to common stockholders - diluted	($5,897,816)	($1,718,878)	($7,447,527)	($5,816,971)
Basic	'	'	'	'
Weighted-average number of common shares - basic	3,737,675	314,419	2,041,941	314,419
Diluted	'	'	'	'
Weighted-average number of common shares - basic	3,737,675	314,419	2,041,941	314,419
Warrants (treasury stock)	31,685	'	65,448	'
Total weighted average number of common shares - diluted	3,769,360	314,419	2,107,389	314,419
Net loss per share:	'	'	'	'
Basic	($1.43)	($5.47)	($2.51)	($18.50)
Diluted	($1.56)	($5.47)	($3.53)	($18.50)

Net_Loss_Attributable_to_Commo3

Net Loss Attributable to Common Stockholders - Computation of Diluted Weighted-Average Shares Outstanding (Detail)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	1,336,836	4,578,205	2,537,413	4,564,484
Options to purchase stock [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	87,241	67,232	87,258	67,232
Warrants to purchase Preferred Stock [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	'	67,376	'	65,439
Preferred Stock [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	1,240,955	3,642,799	2,435,245	3,642,799
Convertible note payable-related parties [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	8,640	'	14,910	'
Rights to receive warrants for Preferred Stock [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	'	160,160	'	157,803
Investor rights to purchase Preferred Stock [Member]	'	'	'	'
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]	'	'	'	'
Total of common equivalent shares	'	640,638	'	631,211

Fair_Value_Measurements_Additi

Fair Value Measurements - Additional Information (Detail) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Fair Value Disclosures [Abstract]	'	'
Liabilities measured at fair value on a recurring basis	$0	$3,518,867

Fair_Value_Measurements_Schedu

Fair Value Measurements - Schedule of Liabilities Measured at Fair Value on Recurring Basis (Detail) (USD $)	Jun. 30, 2014	Dec. 31, 2013
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	$0	$3,518,867
Warrant [Member] \| Series B Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	3,439,059
Warrant [Member] \| Series A Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	79,808
Level 1 [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 1 [Member] \| Warrant [Member] \| Series B Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 1 [Member] \| Warrant [Member] \| Series A Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 2 [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 2 [Member] \| Warrant [Member] \| Series B Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 2 [Member] \| Warrant [Member] \| Series A Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	'
Level 3 [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	3,518,867
Level 3 [Member] \| Warrant [Member] \| Series B Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	3,439,059
Level 3 [Member] \| Warrant [Member] \| Series A Preferred Stock [Member]	'	'
Liabilities:	'	'
Liabilities measured at fair value on a recurring basis	'	$79,808

Fair_Value_Measurements_Schedu1

Fair Value Measurements - Schedule of Reconciliation of Liabilities Measured at Fair Value on Recurring Basis (Detail) (USD $)	3 Months Ended		6 Months Ended			12 Months Ended	6 Months Ended	12 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Dec. 31, 2013	Jun. 30, 2014	Dec. 31, 2013
					Warrant [Member]	Warrant [Member]	Warrant [Member]	Warrant [Member]
					Series A Preferred Stock [Member]	Series A Preferred Stock [Member]	Series B Preferred Stock [Member]	Series B Preferred Stock [Member]
Fair Value Of Assets And Liabilities Measured On Non Recurring Basis [Line Items]	'	'	'	'	'	'	'	'
Balance at beginning of period	'	'	$3,518,867	'	$79,808	$87,600	$3,439,059	$2,180,500
Net exercise of Series A Warrants	'	'	'	'	-29,247	'	-1,162,118	'
Exercise of warrants purchase rights into Series B Warrants	'	'	'	'	'	'	0	1,793,600
Warrant liability - Series B	'	'	'	'	'	'	0	177,952
Change in fair value	567,588	-36,100	2,327,502	-313,600	-50,561	-7,792	-2,276,941	-712,993
Balance at end of period	$0	'	$0	'	$0	$79,808	$0	$3,439,059

Fair_Value_Measurements_Schedu2

Fair Value Measurements - Schedule of Inputs Used by Instrument to Determine the Fair Value Measurements (Detail) (USD $)	12 Months Ended
	Dec. 31, 2013
Series A Preferred Stock [Member]	'
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]	'
Preferred stock warrant liability, Expected dividend yield	0.00%
Preferred stock warrant liability, Anticipated volatility	88.57%
Preferred stock warrant liability, Estimated stock price	$45.20
Preferred stock warrant liability, Exercise price	$12.24
Preferred stock warrant liability, Expected life (years)	'5 years 3 months 11 days
Preferred stock warrant liability, Risk free interest rate	1.75%
Series B Preferred Stock [Member]	'
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]	'
Preferred stock warrant liability, Expected dividend yield	0.00%
Preferred stock warrant liability, Anticipated volatility	88.57%
Preferred stock warrant liability, Estimated stock price	$19.92
Preferred stock warrant liability, Exercise price	$5.16
Minimum [Member] \| Series B Preferred Stock [Member]	'
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]	'
Preferred stock warrant liability, Expected life (years)	'3 years 11 months 19 days
Preferred stock warrant liability, Risk free interest rate	0.78%
Maximum [Member] \| Series B Preferred Stock [Member]	'
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]	'
Preferred stock warrant liability, Expected life (years)	'6 years 10 months 21 days
Preferred stock warrant liability, Risk free interest rate	2.45%

Convertible_Notes_Payable_Rela1

Convertible Notes Payable - Related Parties - Additional Information (Detail) (USD $)	1 Months Ended	6 Months Ended
	Oct. 31, 2013	Jun. 30, 2014
Short-term Debt [Line Items]	'	'
Convertible note interest rate	6.00%	'
Due and payable date of convertible note	'2014-06	'
Convertible note payable-related parties [Member]	'	'
Short-term Debt [Line Items]	'	'
Convertible promissory note	$170,000	'
Convertible note interest rate	6.00%	'
Convertible note maturity extended date	28-Feb-14	'
Initial public offering	'	'May 2014
Converted into common stock	'	21,250

Credit_Facility_Additional_Inf

Credit Facility - Additional Information (Detail) (USD $)

0 Months Ended

6 Months Ended

12 Months Ended

0 Months Ended

6 Months Ended

0 Months Ended

Nov. 20, 2013

Apr. 12, 2012

Jun. 30, 2014

Dec. 31, 2012

Nov. 20, 2013

Apr. 12, 2012

Nov. 20, 2013

Jun. 30, 2014

Nov. 20, 2013

Apr. 12, 2012

Nov. 20, 2013

Aug. 14, 2013

Dec. 20, 2012

Payments

Credit Facility [Member]

Series A Preferred Stock [Member]

Series B Preferred Stock [Member]

Line of Credit Facility [Line Items]

Amount borrowing under credit facility

$500,000

Credit Facility, interest accrued description

'To provide additional capital for general working capital purposes and for capital expenditures. Interest accrued from the date of each advance equal to the greater of (a) 2.75% above the prime rate then in effect per annum, or (b) 6.50% per annum.

Amounts outstanding payable frequency

'24 equal monthly installments

Monthly installment beginning date

12-May-13

Monthly installment maturity date

13-Apr-15

Penalties for prepayment of the principal balance

Interest rate per annum

6.50%

Warrant issued to purchase shares of Series A Preferred Stock

2,042

9,692

96,921

Warrant value

177,952

88,100

Loan and security agreement basis spread on prime rate

2.75%

Maximum borrowings under credit facility

500,000

Number of advance payments received

Monthly interest payments end date

12-Apr-13

Monthly principal payments

20,833

Current borrowings capacity under credit facility

1,000,000

Advance payment received in November 2013 through term loan

1,000,000

Credit Facility, period of interest only payments

'November 2013 through November 2014

Principal payments

58,160

Maturity period of term loans

'2016-11

Warrant exercisable

9,692

Exercise price of warrants per share

12.24

5.16

Warrant exercisable, term

'7 years

Net of debt discount amount

$172,889

Credit facility maturity date

'2016-11

Income_Taxes_Additional_Inform

Income Taxes - Additional Information (Detail) (USD $)	6 Months Ended
Income Taxes - Additional Information (Detail) (USD $)	Jun. 30, 2014
Income Tax Disclosure [Abstract]	'
Provision for income tax benefit	$0
Deferred tax assets valuation allowance	100.00%

Stock_Incentive_Plan_Additiona

Stock Incentive Plan - Additional Information (Detail) (USD $)	3 Months Ended	6 Months Ended
	Jun. 30, 2014	Jun. 30, 2014	Dec. 31, 2013
	Jun. 30, 2014	Incentive_Plan	Dec. 31, 2013
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Number of incentive plans	'	3	'
Number of stock options outstanding	764,990	764,990	609,842
Exercise price per share of common stock	$2.80	$2.80	$1.48
Options exercisable	115,622	115,622	'
Expense relating to options	$340,372	$340,372	'
Number of options granted	155,148	'	'
Average exercise price of stock options granted	$8	'	'
Consultants [Member]	'	'	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Number of options granted	'	0	'
2004 Plan [Member]	'	'	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Stock incentive plans, contractual term	'	'Seven years	'
Stock incentive plan, termination date	'	'August 2010	'
Number of stock options outstanding	23,954	23,954	'
Exercise price per share of common stock	$3.24	$3.24	'
2013 Plan [Member]	'	'	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Issuance of common stock authorized	625,000	625,000	'
Shares available for issuance	469,852	469,852	'
Percentage of increase in common shares outstanding	'	4.00%	'
Increase in common stock outstanding	$333,333	$333,333	'
Two grants [Member]	'	'	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Options exercisable	'	'	32,014
2010 Plan [Member]	'	'	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'	'	'
Issuance of common stock authorized	681,788	681,788	'
Shares available for issuance	0	0	'

Stock_Incentive_Plan_Summary_o

Stock Incentive Plan - Summary of Stock Options Exercisable (Detail)	6 Months Ended
	Jun. 30, 2014
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]	'
Number Exercisable	115,622
Outstanding Shares Weighted- Average Remaining Contractual Life	'9 years 1 month 13 days
Exercisable Shares Weighted- Average Remaining Contractual Life	'7 years 9 months 18 days

Stock_Incentive_Plan_Schedule_

Stock Incentive Plan - Schedule of Fair Value of Stock Option Assumptions (Detail) (Non-employee stock options [Member], USD $)	6 Months Ended
	Jun. 30, 2014
Non-employee stock options [Member]	'
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]	'
Expected dividend yield	0.00%
Expected volatility	88.57%
Estimated stock price	$6.56
Exercise price	$0.55
Expected life (years)	'9 years 2 months 10 days
Risk free interest rate	2.40%

Stock_Incentive_Plan_Schedule_1

Stock Incentive Plan - Schedule of Stock-Based Compensation Expense (Detail) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]	'	'	'	'
Total stock-based compensation expense	$748,422	$624,377	$1,114,107	$674,824
Research and development expenses [Member]	'	'	'	'
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]	'	'	'	'
Total stock-based compensation expense	203,474	156,846	282,000	206,165
General and administrative expenses [Member]	'	'	'	'
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]	'	'	'	'
Total stock-based compensation expense	$544,948	$467,531	$832,107	$468,659

Contributed_Services_Additiona

Contributed Services - Additional Information (Detail) (USD $)	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Commitments And Contingencies Disclosure [Abstract]	'	'	'	'
Contributed services description	'	'	'During the period from January 6, 2012 through October 14, 2013, he was not paid a salary by the Company and was an employee and paid a salary by Domain Associates, LLC (Domain), a related party. The value of his services has been reflected in the statement of operations as an expense and recorded as a contribution of capital.	'
Contributed services fee to President and Chief Executive Officer	$0	$78,000	$0	$120,000

Redeemable_Convertible_Preferr1

Redeemable Convertible Preferred Stock - Additional Information (Detail) (USD $)	6 Months Ended
In Millions, except Share data, unless otherwise specified	Jun. 30, 2014	7-May-14
	Jun. 30, 2014	Initial Public Offering [Member]
Temporary Equity [Line Items]	'	'
Initial public offering completion date	7-May-14	'
Common stock issued in initial public offering	'	1,500,000
Common stock issued price per share	'	$8
Aggregate offering price	'	$12
Proceeds from initial public offering net of underwriting discounts, commissions and offering costs	10	'
Underwriting discounts and commissions	0.8	'
Prepaid offering and printing costs	1	'
Offering costs	$0.20	'
Voting rights interest	67.00%	'
Conversion of preferred stock into common stock	3,642,800	'

Stock_Purchase_Warrants_Additi

Stock Purchase Warrants - Additional Information (Detail)	6 Months Ended					6 Months Ended
	Jun. 30, 2014	Nov. 20, 2013	Aug. 14, 2013	Dec. 20, 2012	Apr. 12, 2012	Jun. 30, 2014
	Warrant [Member]	Series B Preferred Stock [Member]	Series B Preferred Stock [Member]	Series B Preferred Stock [Member]	Series A Preferred Stock [Member]	Series A And Series B Preferred Stock [Member]
Class of Warrant or Right [Line Items]	'	'	'	'	'	'
Warrants to purchase shares	60,000	9,692	96,921	96,921	2,042	'
Exercise price of warrants per share	10	5.16	5.16	5.16	12.24	'
Conversion of preferred stock into common stock	'	'	'	'	'	74,001
Warrants exercisable date	1-May-15	'	'	'	'	'
Warrants expiration date	1-May-19	'	'	'	'	'

Related_Party_Transactions_Add

Related Party Transactions - Additional Information (Detail) (USD $)	1 Months Ended
	31-May-14	Oct. 31, 2013
Related Party Transactions [Abstract]	'	'
Convertible promissory note principal amount	'	$170,000
Convertible promissory note interest rate	'	6.00%
Debt converted to common stock	21,250	'

Commitments_and_Contingencies_

Commitments and Contingencies - Additional Information (Detail) (USD $)	6 Months Ended
	Jun. 30, 2014	Feb. 28, 2010
Commitments And Contingencies Disclosure [Abstract]	'	'
Outstanding material claims	$0	'
Reserve for indemnification	0	'
Milestone payments upon reaching development and regulatory milestone	'	$2,150,000
License and supply agreement termination description	'The license and supply agreement runs through the 7th anniversary of the expiration of all patents licensed under the agreement, which the Company estimates to be April 2036, unless terminated earlier.	'