Exhibit 12.1
ALEXZA PHARMACEUTICALS, INC.
COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES
(in thousands)
COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES
(in thousands)
Fiscal Year Ended December 31, | ||||||||||||||||||||
2009 | 2008 | 2007 | 2006 | 2005 | ||||||||||||||||
EARNINGS: | ||||||||||||||||||||
Loss before income taxes | $ | (56,065 | ) | $ | (77,041 | ) | $ | (55,910 | ) | $ | (53,526 | ) | $ | (32,402 | ) | |||||
Plus: fixed charges (see below) | 1,382 | 2,368 | 2,624 | 1,532 | 700 | |||||||||||||||
Less: capitalized interest | — | — | — | — | — | |||||||||||||||
Total earnings (loss) to cover fixed charges | (54,683 | ) | (74,673 | ) | (53,286 | ) | (51,994 | ) | (31,702 | ) | ||||||||||
FIXED CHARGES: | ||||||||||||||||||||
Interest expense | 438 | 897 | 954 | 743 | 311 | |||||||||||||||
Amortization of debt discount and deferred interest | 29 | 38 | 49 | 35 | 47 | |||||||||||||||
Interest portion of rental expense | 915 | 1,433 | 1,621 | 754 | 342 | |||||||||||||||
Total Fixed Charges | 1,382 | 2,368 | 2,624 | 1,532 | 700 | |||||||||||||||
DEFICIENCY OF EARNINGS TO COVER FIXED CHARGES | $ | (56,065 | ) | $ | (77,041 | ) | $ | (55,910 | ) | $ | (53,526 | ) | $ | (32,402 | ) |