Exhibit 12.1
ALEXZA PHARMACEUTICALS, INC.
COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES
(in thousands)
COMPUTATION OF RATIOS OF EARNINGS TO FIXED CHARGES
(in thousands)
Fiscal Year Ended December 31, | ||||||||||||||||||||
2006 | 2005 | 2004 | 2003 | 2002 | ||||||||||||||||
EARNINGS: | ||||||||||||||||||||
Loss before income taxes | $ | (41,806 | ) | $ | (32,402 | ) | $ | (16,625 | ) | $ | (14,328 | ) | $ | (8,163 | ) | |||||
Plus: fixed charges (see below) | 1,532 | 716 | 459 | 379 | 255 | |||||||||||||||
Less: capitalized interest | — | — | — | — | — | |||||||||||||||
Total earnings (loss) to cover fixed charges | (40,274 | ) | (31,686 | ) | (16,166 | ) | (13,949 | ) | (7,908 | ) | ||||||||||
FIXED CHARGES: | ||||||||||||||||||||
Interest expense | 743 | 311 | 140 | 94 | 80 | |||||||||||||||
Amortization of debt discount and deferred interest | 35 | 47 | 86 | 84 | 23 | |||||||||||||||
Interest portion of rental expense | 754 | 358 | 233 | 201 | 152 | |||||||||||||||
Total Fixed Charges | 1,532 | 716 | 459 | 379 | 255 | |||||||||||||||
DEFICIENCY OF EARNINGS TO COVER FIXED CHARGES | $ | (41,806 | ) | $ | (32,402 | ) | $ | (16,625 | ) | $ | (14,328 | ) | $ | (8,163 | ) | |||||