ADMA Biologics (ADMA) 10-Q 10 Aug 22 2022 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2022	Aug. 05, 2022
Cover [Abstract]
Document Type	10-Q
Amendment Flag	false
Document Quarterly Report	true
Document Period End Date	Jun. 30, 2022
Current Fiscal Year End Date	--12-31
Document Fiscal Year Focus	2022
Document Fiscal Period Focus	Q2
Document Transition Report	false
Entity File Number	001-36728
Entity Registrant Name	ADMA BIOLOGICS, INC.
Entity Central Index Key	0001368514
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	56-2590442
Entity Address, Address Line One	465 State Route 17
Entity Address, City or Town	Ramsey
Entity Address, State or Province	NJ
Entity Address, Postal Zip Code	07446
City Area Code	201
Local Phone Number	478-5552
Title of 12(b) Security	Common Stock
Trading Symbol	ADMA
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		196,357,149

CONDENSED CONSOLIDATED BALANCE

CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 52,415,053	$ 51,089,118
Accounts receivable, net	18,883,847	28,576,857
Inventories	146,075,459	124,724,091
Prepaid expenses and other current assets	5,399,928	4,339,245
Total current assets	222,774,287	208,729,311
Property and equipment, net	54,951,267	50,935,074
Intangible assets, net	1,371,092	1,728,768
Goodwill	3,529,509	3,529,509
Right-to-use assets	10,550,236	7,262,658
Deposits and other assets	3,755,938	4,067,404
TOTAL ASSETS	296,932,329	276,252,724
Current liabilities:
Accounts payable	11,388,048	12,429,409
Accrued expenses and other current liabilities	15,961,070	17,214,988
Current portion of deferred revenue	142,834	142,834
Current portion of lease obligations	579,661	591,084
Total current liabilities	28,071,613	30,378,315
Senior notes payable, net of discount	139,810,931	94,866,239
Deferred revenue, net of current portion	1,904,448	1,975,865
End of term fee	1,500,000	0
Lease obligations, net of current portion	10,870,907	7,462,388
Other non-current liabilities	373,903	397,351
TOTAL LIABILITIES	182,531,802	135,080,158
COMMITMENTS AND CONTINGENCIES
STOCKHOLDERS' EQUITY
Preferred Stock, $0.0001 par value, 10,000,000 shares authorized, no shares issued and outstanding	0	0
Common Stock - voting, $0.0001 par value, 300,000,000 shares authorized, 196,356,232 and 195,813,817 shares issued and outstanding	19,636	19,581
Additional paid-in capital	565,266,375	553,265,706
Accumulated deficit	(450,885,484)	(412,112,721)
TOTAL STOCKHOLDERS' EQUITY	114,400,527	141,172,566
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY	$ 296,932,329	$ 276,252,724

CONDENSED CONSOLIDATED BALANC_2

CONDENSED CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares	Jun. 30, 2022	Dec. 31, 2021
STOCKHOLDERS' EQUITY
Preferred stock, par value (in dollars per share)	$ 0.0001	$ 0.0001
Preferred stock, shares authorized (in shares)	10,000,000	10,000,000
Preferred stock, shares issued (in shares)	0	0
Preferred stock, shares outstanding (in shares)	0	0
Common stock, par value (in dollars per share)	$ 0.0001	$ 0.0001
Common stock, shares authorized (in shares)	300,000,000	300,000,000
Common stock, shares issued (in shares)	196,356,232	195,813,817
Common stock, shares outstanding (in shares)	196,356,232	195,813,817

CONDENSED CONSOLIDATED STATEMEN

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
REVENUES:
Revenues	$ 33,905,007	$ 17,830,590	$ 63,008,100	$ 33,879,208
Cost of product revenue	26,135,614	18,832,624	51,576,660	36,602,746
Gross profit (loss)	7,769,393	(1,002,034)	11,431,440	(2,723,538)
OPERATING EXPENSES:
Research and development	873,386	1,158,866	1,497,497	2,146,515
Plasma center operating expenses	3,921,486	2,803,326	7,896,075	5,045,669
Amortization of intangible assets	178,838	178,838	357,676	357,676
Selling, general and administrative	11,970,422	10,438,168	25,669,997	20,472,083
Total operating expenses	16,944,132	14,579,198	35,421,245	28,021,943
LOSS FROM OPERATIONS	(9,174,739)	(15,581,232)	(23,989,805)	(30,745,481)
OTHER INCOME (EXPENSE):
Interest income	2,269	5,926	35,337	27,985
Interest expense	(4,573,015)	(3,246,680)	(7,962,053)	(6,442,430)
Loss on extinguishment of debt	0	0	(6,669,941)	0
Other expense	(19,421)	(83,317)	(186,301)	(125,318)
Other expense, net	(4,590,167)	(3,324,071)	(14,782,958)	(6,539,763)
NET LOSS	$ (13,764,906)	$ (18,905,303)	$ (38,772,763)	$ (37,285,244)
BASIC LOSS PER COMMON SHARE (in dollars per share)	$ (0.07)	$ (0.15)	$ (0.20)	$ (0.31)
DILUTED LOSS PER COMMON SHARE (in dollars per share)	$ (0.07)	$ (0.15)	$ (0.20)	$ (0.31)
WEIGHTED AVERAGE COMMON SHARES OUTSTANDING:
Basic (in shares)	196,353,185	127,416,126	196,113,888	121,571,501
Diluted (in shares)	196,353,185	127,416,126	196,113,888	121,571,501
Product Revenue [Member]
REVENUES:
Revenues	$ 33,869,298	$ 17,794,881	$ 62,936,683	$ 33,807,791
License Revenue [Member]
REVENUES:
Revenues	$ 35,709	$ 35,709	$ 71,417	$ 71,417

CONDENSED CONSOLIDATED STATEM_2

CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Total
Balance at Dec. 31, 2020	$ 10,490	$ 428,704,039	$ (340,465,103)	$ 88,249,426
Balance (in shares) at Dec. 31, 2020	104,902,888
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 0	781,397	0	781,397
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired	$ 6	(59,317)	0	(59,311)
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired (in shares)	61,385
Issuance of common stock, net of offering expenses	$ 1,808	41,910,707	0	41,912,515
Issuance of common stock, net of offering expenses (in shares)	18,080,708
Net loss	$ 0	0	(18,379,941)	(18,379,941)
Balance at Mar. 31, 2021	$ 12,304	471,336,826	(358,845,044)	112,504,086
Balance (in shares) at Mar. 31, 2021	123,044,981
Balance at Dec. 31, 2020	$ 10,490	428,704,039	(340,465,103)	88,249,426
Balance (in shares) at Dec. 31, 2020	104,902,888
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss				(37,285,244)
Balance at Jun. 30, 2021	$ 13,187	489,330,692	(377,750,347)	111,593,532
Balance (in shares) at Jun. 30, 2021	131,872,026
Balance at Mar. 31, 2021	$ 12,304	471,336,826	(358,845,044)	112,504,086
Balance (in shares) at Mar. 31, 2021	123,044,981
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 0	805,189	0	805,189
Issuance of common stock, net of offering expenses	$ 883	17,188,677	0	17,189,560
Issuance of common stock, net of offering expenses (in shares)	8,827,045
Net loss	$ 0	0	(18,905,303)	(18,905,303)
Balance at Jun. 30, 2021	$ 13,187	489,330,692	(377,750,347)	111,593,532
Balance (in shares) at Jun. 30, 2021	131,872,026
Balance at Dec. 31, 2021	$ 19,581	553,265,706	(412,112,721)	141,172,566
Balance (in shares) at Dec. 31, 2021	195,813,817
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 0	1,641,388	0	1,641,388
Warrants issued in connection with note payable	0	9,569,604	0	9,569,604
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired	$ 54	(442,690)	0	(442,636)
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired (in shares)	533,712
Net loss	$ 0	0	(25,007,857)	(25,007,857)
Balance at Mar. 31, 2022	$ 19,635	564,034,008	(437,120,578)	126,933,065
Balance (in shares) at Mar. 31, 2022	196,347,529
Balance at Dec. 31, 2021	$ 19,581	553,265,706	(412,112,721)	141,172,566
Balance (in shares) at Dec. 31, 2021	195,813,817
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss				(38,772,763)
Balance at Jun. 30, 2022	$ 19,636	565,266,375	(450,885,484)	114,400,527
Balance (in shares) at Jun. 30, 2022	196,356,232
Balance at Mar. 31, 2022	$ 19,635	564,034,008	(437,120,578)	126,933,065
Balance (in shares) at Mar. 31, 2022	196,347,529
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation	$ 0	1,191,047	0	1,191,047
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired	$ 1	41,320	0	41,321
Vesting of Restricted Stock Units, net of shares withheld for taxes and retired (in shares)	8,703
Net loss	$ 0	0	(13,764,906)	(13,764,906)
Balance at Jun. 30, 2022	$ 19,636	$ 565,266,375	$ (450,885,484)	$ 114,400,527
Balance (in shares) at Jun. 30, 2022	196,356,232

CONDENSED CONSOLIDATED STATEM_3

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:
Net loss	$ (38,772,763)	$ (37,285,244)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	3,314,500	2,555,622
Loss on disposal of fixed assets	2,638	78,135
Interest paid in kind	1,045,660	0
Stock-based compensation	2,832,435	1,586,586
Amortization of debt discount	927,061	908,151
Loss on extinguishment of debt	6,669,941	0
Amortization of license revenue	(71,417)	(71,417)
Changes in operating assets and liabilities:
Accounts receivable	9,693,011	(10,307,304)
Inventories	(21,351,368)	(18,164,144)
Prepaid expenses and other current assets	(1,060,683)	(2,655,397)
Deposits and other assets	684,777	(144,657)
Accounts payable	(1,041,361)	(4,906,244)
Accrued expenses	(1,461,621)	2,980,534
Other current and non-current liabilities	(254,991)	(65,984)
Net cash used in operating activities	(38,844,181)	(65,491,363)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchase of property and equipment	(6,782,169)	(7,046,735)
Net cash used in investing activities	(6,782,169)	(7,046,735)
CASH FLOWS FROM FINANCING ACTIVITIES:
Principal payments on notes payable	(100,000,000)	0
Proceeds from issuance of common stock, net of offering expenses	0	59,102,075
Payment of debt refinancing fees	(2,000,000)	0
Proceeds from issuance of note payable	151,750,000	0
Taxes paid on vested Restricted Stock Units	(401,315)	(59,311)
Payments on finance lease obligations	(18,034)	(16,860)
Payment of deferred financing fees	(2,378,366)	0
Net cash provided by financing activities	46,952,285	59,025,904
Net increase (decrease) in cash and cash equivalents	1,325,935	(13,512,194)
Cash and cash equivalents - beginning of period	51,089,118	55,921,152
Cash and cash equivalents - end of period	$ 52,415,053	$ 42,408,958

ORGANIZATION AND BUSINESS

ORGANIZATION AND BUSINESS	6 Months Ended
	Jun. 30, 2022
ORGANIZATION AND BUSINESS [Abstract]
ORGANIZATION AND BUSINESS	1. ORGANIZATION AND BUSINESS ADMA Biologics, Inc. (“ADMA” or the “Company”) is an end-to-end commercial biopharmaceutical company dedicated to manufacturing, marketing and developing specialty plasma-derived biologics for the treatment of immunodeficient patients at risk for infection and others at risk for certain infectious diseases. The Company’s targeted patient populations include immune-compromised individuals who suffer from an underlying immune deficiency disorder or who may be immune-suppressed for medical reasons. ADMA operates through its wholly-owned subsidiaries ADMA BioManufacturing, LLC (“ADMA BioManufacturing”) and ADMA BioCenters Georgia Inc. (“ADMA BioCenters”). ADMA BioManufacturing was formed in January 2017 to facilitate the acquisition of the Biotest Therapy Business Unit (“BTBU”) from BPC Plasma, Inc. (formerly Biotest Pharmaceuticals Corporation) (“BPC” and, together with Biotest AG, “Biotest”) on June 6, 2017. The acquisition included certain assets of BTBU, including the U.S. Food and Drug Administration (“FDA”)-licensed BIVIGAM and Nabi-HB immunoglobulin products, and an FDA-licensed plasma fractionation manufacturing facility located in Boca Raton, FL (the “Boca Facility”) (the “Biotest Transaction”). BTBU had previously been the Company’s third-party contract manufacturer. ADMA BioCenters is the Company’s source plasma collection business with ten plasma collection facilities in various stages of approval and development located throughout the U.S., six of which hold an approved license with the FDA, with two additional collection facilities in operation and collecting plasma presently under FDA licensing preparation and review and another two facilities under construction. The Company has three FDA-approved products, all of which are currently marketed and commercially available: (i) BIVIGAM (Immune Globulin Intravenous, Human), an Intravenous Immune Globulin (“IVIG”) product indicated for the treatment of Primary Humoral Immunodeficiency (“PI”), also known as Primary Immunodeficiency Disease (“PIDD”), and for which the Company received FDA approval on May 9, 2019 and commenced commercial sales in August 2019; (ii) ASCENIV (Immune Globulin Intravenous, Human – slra 10% Liquid), an IVIG product indicated for the treatment of PI, for which the Company received FDA approval on April 1, 2019 and commenced first commercial sales in October 2019; and (iii) Nabi-HB (Hepatitis B Immune Globulin, Human), which is indicated for the treatment of acute exposure to blood containing Hepatitis B surface antigen (“HBsAg”) and other listed exposures to Hepatitis B. In addition to its commercially available immunoglobulin products, the Company provides contract manufacturing and laboratory services for certain clients and generates revenues from the sale of intermediate by-products that result from the immunoglobulin production process. The Company seeks to develop a pipeline of plasma-derived therapeutics, and its products and product candidates are intended to be used by physician specialists focused on caring for immune-compromised patients with or at risk for certain infectious diseases. As of June 30, 2022, the Company had working capital of $194.7 million, including $52.4 million of cash and cash equivalents. Based upon the Company’s current projected revenue and expenditures, including capital expenditures and continued implementation of the Company’s commercialization and expansion activities, the Company’s management currently believes that its cash, cash equivalents, projected revenue and accounts receivable, together with the remaining available funds under the distribution agreement entered into in September of 2021 (see Note 8) and the net proceeds received and expected to be received from the refinancing of the Company’s senior debt on March 23, 2022 (see Note 7), will be sufficient to fund ADMA’s operations, as currently conducted, into the first quarter of 2024, at which time the Company believes it will begin to generate positive cash flow from operations. These estimates may change based upon several factors, including the success of the Company’s commercial efforts with respect to the sale of its products, whether or not the assumptions underlying the Company’s projected revenues and expenses are correct and the acceptability of ADMA’s immune globulin products by physicians, patients or payers. can be no assurance that the Company’s approved products will be commercially viable, or that plant capacity expansion, plasma center buildouts or other capital improvements will be successfully completed or that any product developed in the future will be approved. The Company is subject to risks common to companies in the biotechnology and pharmaceutical manufacturing industries including, but not limited to, dependence on collaborative arrangements, development by the Company or its competitors of new technological innovations, dependence on key personnel, inflationary pressures, supply chain constraints, protection of proprietary technology and compliance with FDA and other governmental regulations and approval requirements. The Company is also continuing to evaluate a variety of strategic alternatives through its ongoing engagement with Morgan Stanley as a financial advisor.

SUMMARY OF SIGNIFICANT ACCOUNTI

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES	6 Months Ended
	Jun. 30, 2022
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES	2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Basis of Presentation The accompanying unaudited condensed consolidated financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information. Any reference in these notes to applicable guidance is meant to refer to U.S. GAAP as found in the Accounting Standards Codification (“ASC”) and Accounting Standards Updates (“ASU”) of the Financial Accounting Standards Board (the “FASB”). The accompanying unaudited condensed consolidated financial statements should be read in conjunction with the annual audited consolidated financial statements and notes thereto as of and for the year ended December 31, 2021 included in the Company’s Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (the “SEC”) on March 24, 2022. The accompanying consolidated balance sheet as of December 31, 2021 was derived from the audited financial statements as of and for the year ended December 31, 2021. These condensed consolidated interim financial statements have been prepared in accordance with the instructions to Form 10-Q and Article 8 of Regulation S-X, and therefore omit or condense certain footnotes and other information normally included in complete consolidated financial statements prepared in accordance with U.S. GAAP. All intercompany balances and transactions have been eliminated in consolidation. In the opinion of management, the accompanying unaudited condensed consolidated financial statements include all normal and recurring adjustments (which consist primarily of accruals, estimates and assumptions that impact the financial statements) considered necessary to present fairly the Company’s financial position as of June 30, 2022, its results of operations and changes in stockholders’ equity for the three and six months ended June 30, 2022 and 2021 and cash flows for the six months ended June 30, 2022 and 2021. During the three and six months ended June 30 Use of Estimates The preparation of financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. Significant estimates include rebates and chargebacks deducted from gross revenues, the realizable value of accounts receivable, valuation of inventory, assumptions used in projecting future liquidity and capital requirements, assumptions used in the fair value of awards granted under the Company’s equity incentive plans and warrants issued in connection with the issuance of notes payable and the valuation allowance for the Company’s deferred tax assets. Fair Value of Financial Instruments The carrying amounts of certain of the Company’s financial instruments, including cash and cash equivalents, accounts receivable and accounts payable, are shown at cost which approximates fair value due to the short-term nature of these instruments. The debt outstanding under the Company’s senior secured term loan (see Note 7) approximates fair value due to the variable interest rate on this debt. Accounts Receivable Accounts receivable is reported at realizable value, net of allowances for contractual credits and doubtful accounts in the amount of $0.1 million and $0.2 million at June 30 The Company extends credit to its customers based upon an evaluation of each customer’s financial condition and credit history. Evaluations of the financial condition and associated credit risk of customers are performed on an ongoing basis. June 30 Inventories Raw materials inventory consists of various materials purchased from suppliers, including normal source plasma, used in the production of the Company’s products. Work-in-process and finished goods inventories (see Note 3) reflect the cost of raw materials as well as costs for direct and indirect labor, primarily salaries, wages and benefits for applicable employees, as well as an allocation of overhead costs related to the Boca Facility including utilities, property taxes, general repairs and maintenance, consumable supplies and depreciation. The allocation of Boca Facility overhead to inventory is generally based upon the estimated square footage of the Boca Facility that is used in the production of the Company’s products relative to the total square footage of the facility. Inventories, including plasma intended for resale and plasma intended for internal use in the Company’s manufacturing, commercialization or research and development activities, are carried at the lower of cost or net realizable value determined by the first-in, first-out method. Net realizable value is generally determined based upon the consideration the Company expects to receive when the inventory is sold, less costs to deliver the inventory to the recipient. The estimates for net realizable value of inventory are based on contractual terms or upon historical experience and certain other assumptions, and the Company believes that such assumptions are reasonable. Inventory is periodically reviewed to ensure that its carrying value does not exceed its net realizable value, and adjustments are recorded to write down such inventory, with a corresponding charge to cost of product revenue, when the carrying value or historical cost exceeds its estimated net realizable value. In addition, costs associated with the production of conformance or engineering lots that would not qualify as immediately available for commercial sale are charged to cost of product revenue and not capitalized into inventory. Goodwill Goodwill represents the excess of purchase price over the fair value of net assets acquired by the Company. Goodwill at June 30, 2022 and December 31, 2021 was $3.5 million. All of the Company’s goodwill is attributable to its ADMA BioManufacturing business segment and is related to the Biotest Transaction. Goodwill is not amortized but is assessed for impairment on an annual basis or more frequently if impairment indicators exist. The Company has the option to perform a qualitative assessment of goodwill to determine whether it is more likely than not that the fair value of its reporting unit is less than its carrying amount, including goodwill and other intangible assets. If the Company concludes that this is the case, then it must perform a goodwill impairment test by comparing the fair value of the reporting unit to its carrying value. An impairment charge is recorded to the extent the reporting unit’s carrying value exceeds its fair value, not to exceed the total amount of goodwill allocated to that reporting unit. The Company performs its annual goodwill impairment test as of October 1 of each year. The Company’s annual goodwill impairment test as of October 1, 2021 did not result in a goodwill impairment charge, and the Company did not record any impairment charges related to goodwill for the six months ended June 30, 2022 and 2021. Impairment of Long-Lived Assets The Company assesses the recoverability of its long-lived assets, which include property and equipment and finite-lived intangible assets, whenever significant events or changes in circumstances indicate impairment may have occurred. If indicators of impairment exist, projected future undiscounted cash flows associated with the asset are compared to its carrying amount to determine whether the asset’s carrying value is recoverable. Any resulting impairment is recorded as a reduction in the carrying value of the related asset in excess of fair value and a charge to operating results. For the six months ended June 30 Revenue Recognition Revenues for the three and six months ended June 30 Product revenue is recognized when the customer is deemed to have control over the product. Control is determined based on when the product is shipped or delivered and title passes to the customer. Revenue is recorded in an amount that reflects the consideration the Company expects to receive in exchange. Revenue from the sale of the Company’s immunoglobulin products is recognized when the product reaches the customer’s destination, and is recorded net of estimated rebates, price protection arrangements and customer incentives, including prompt pay discounts, wholesaler chargebacks and other wholesaler fees. These estimates are based on historical experience and certain other assumptions, and the Company believes that such estimates are reasonable. For revenues associated with contract manufacturing and the sale of intermediates, control transfers to the customer and the performance obligation is satisfied when the customer takes possession of the product from the Boca Facility or from a third-party warehouse that is utilized by the Company. Product revenues from the sale of human plasma collected at the Company’s plasma collection centers are recognized at the time control of the product has been transferred to the customer, which generally occurs at the time of shipment. Product revenues are recognized at the time of delivery if the Company retains control of the product during shipment. For the six months ended June 30 June 30 Cost of Product Revenue Cost of product revenue includes costs associated with the manufacture of the Company’s FDA approved products, intermediates and the sale of human source plasma, as well as expenses related to conformance batch production, process development and scientific and technical operations when these operations are attributable to marketed products. When the activities of these operations are attributable to new products in development, the expenses are classified as research and development expenses. Loss Per Common Share Basic loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of shares of common stock outstanding during the period. Diluted loss per common share is calculated by dividing net loss attributable to common stockholders, as adjusted for the effect of dilutive securities, if any, by the weighted average number of shares of common stock and dilutive common stock outstanding during the period. Potentially dilutive common stock includes the shares of common stock issuable upon the exercise of outstanding stock options and warrants, using the treasury stock method, as well as Restricted Stock Units (“RSUs”). Potentially dilutive common stock is excluded from the diluted loss per common share computation to the extent that it would be anti-dilutive. As a result, no potentially dilutive securities are included in the computation of any of the accompanying diluted loss per share amounts in the accompanying condensed consolidated financial statements as the Company reported a net loss for all periods presented. For the six months ended June 30 , 2022 and 2021, the following securities were excluded from the calculation of diluted loss per common share because of their anti-dilutive effects: For the Six Months Ended June 30, 2022 2021 Stock options 8,504,179 7,783,029 Restricted Stock Units 4,742,383 686,133 Warrants 13,556,898 4,528,160 26,803,460 12,997,322 Stock-Based Compensation The Company follows recognized accounting guidance which requires all equity-based payments, including grants of stock options, to be recognized in the statement of operations as compensation expense based on their fair values at the date of grant. Compensation expense related to awards to employees and directors with service-based vesting conditions is recognized on a straight-line basis over the associated vesting period of the award based on the grant date fair value of the award. Stock options granted under the Company’s equity incentive plans generally have a four-year vesting period and a term of 10 years. Pursuant to ASU No. 2016-09, Improvements to Employee Share-Based Payment Accounting (Topic 718) Income Taxes The Company recognizes deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the consolidated financial statements or its tax returns. Under this method, deferred tax assets and liabilities are recognized for the temporary differences between the tax bases of assets and liabilities and their respective financial reporting amounts at enacted tax rates in effect for the years in which the temporary differences are expected to reverse. The Company records a valuation allowance on its deferred tax assets if it is more likely than not that the Company will not generate sufficient taxable income to utilize its deferred tax assets. The Company is subject to income tax examinations by major taxing authorities for all tax years since 2017 and for previous periods as it relates to the Company’s net operating loss carryforwards. In accordance with U.S. GAAP, the Company is required to determine whether a tax position of the Company is more likely than not to be sustained upon examination by the applicable taxing authority, including resolution of any related appeals or litigation processes, based on the technical merits of the position. The tax benefit to be recognized is measured as the largest amount of benefit that is greater than 50% likely of being realized upon ultimate settlement. Derecognition of a tax benefit previously recognized could result in the Company recording a tax liability that would reduce net assets. Based on its analysis, the Company has determined that it has not incurred any liability for unrecognized tax benefits as of June 30 no adjustments for uncertain tax positions.

INVENTORIES

INVENTORIES	6 Months Ended
	Jun. 30, 2022
INVENTORIES [Abstract]
INVENTORIES	3. INVENTORIES The following table provides the components of inventories: June 30, 2022 December 31, 2021 Raw materials $ 38,321,843 $ 36,755,720 Work-in-process 51,136,409 58,968,535 Finished goods 56,617,207 28,999,836 Total inventories $ 146,075,459 $ 124,724,091 Raw materials includes plasma and other materials expected to be used in the production of BIVIGAM, ASCENIV and Nabi-HB. These materials will be consumed in the production of goods expected to be available for sale or otherwise have alternative uses that provide a probable future benefit. All other activities and materials associated with the production of inventories used in research and development activities are expensed as incurred. Work-in-process inventory primarily consists of bulk drug substance and unlabeled filled vials of the Company’s immunoglobulin products. Finished goods inventory is comprised of immunoglobulin product inventory and related intermediates that are available for commercial sale, as well as plasma collected at the Company’s plasma collection centers which is expected to be sold to third-party customers.

INTANGIBLE ASSETS

INTANGIBLE ASSETS	6 Months Ended
	Jun. 30, 2022
INTANGIBLE ASSETS [Abstract]
INTANGIBLE ASSETS	4. INTANGIBLE ASSETS Intangible assets at June 30, 2022 and December 31, 2021 consist of the following: June 30, 2022 December 31, 2021 Cost Accumulated Amortization Net Cost Accumulated Amortization Net Trademark and other intangible rights related to Nabi-HB $ 4,100,046 $ 2,977,415 $ 1,122,631 $ 4,100,046 $ 2,684,554 $ 1,415,492 Rights to intermediates 907,421 658,960 248,461 907,421 594,145 313,276 $ 5,007,467 $ 3,636,375 $ 1,371,092 $ 5,007,467 $ 3,278,699 $ 1,728,768 All of the Company’s intangible assets were acquired in the Biotest Transaction. Amortization expense related to these intangible assets was $0.4 million for the six months ended June 30, 2022 and 2021 and $0.2 million for the three months ended June 30, 2022 and 2021. Estimated future aggregate amortization expense is expected to be as follows: Remainder of 2022 $ 357,676 2023 715,352 2024 298,064

PROPERTY AND EQUIPMENT

PROPERTY AND EQUIPMENT	6 Months Ended
	Jun. 30, 2022
PROPERTY AND EQUIPMENT [Abstract]
PROPERTY AND EQUIPMENT	5. PROPERTY AND EQUIPMENT Property and equipment and related accumulated depreciation are summarized as follows: June 30, 2022 December 31, 2021 Manufacturing and laboratory equipment $ 17,919,714 $ 16,702,991 Office equipment and computer software 5,133,876 4,082,462 Furniture and fixtures 4,364,091 3,389,140 Construction in process 4,830,287 5,496,222 Leasehold improvements 15,492,458 11,129,639 Land 4,339,441 4,339,441 Buildings and building improvements 19,096,164 19,067,032 71,176,031 64,206,927 Less: Accumulated depreciation (16,224,764 ) (13,271,853 ) Total property, plant and equipment, net $ 54,951,267 $ 50,935,074 Property and equipment are stated at cost less accumulated depreciation. Depreciation is calculated using the straight-line method over the asset’s estimated useful life. Land is not depreciated. The buildings were assigned a useful life of 30 years. Property and equipment other than land and buildings have useful lives ranging from three The Company recorded depreciation expense on property and equipment for the three months ended June 30, 2022 and 2021 of $1.5 million and $ 1.1 million, respectively, and for the six months ended June 30, 2022 and 2021 of $3.0 million and $2.2 million, respectively.

ACCRUED EXPENSES AND OTHER CURR

ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES	6 Months Ended
	Jun. 30, 2022
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES [Abstract]
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES	6. ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES Accrued expenses and other current liabilities at June 30, 2022 and December 31, 2021 are as follows: June 30, 2022 December 31, 2021 Accrued rebates $ 7,764,200 $ 5,040,200 Accrued distribution fees 1,850,105 4,739,651 Accrued incentives 1,951,768 4,066,109 Accrued testing 344,892 1,189,970 Accrued payroll 1,019,912 1,167,072 Other 3,030,193 1,011,986 Total accrued expenses and other current liabilities $ 15,961,070 $ 17,214,988

DEBT

DEBT	6 Months Ended
	Jun. 30, 2022
DEBT [Abstract]
DEBT	7. DEBT A summary of outstanding senior notes payable is as follows: June 30, 2022 December 31, 2021 Notes payable $ 152,795,660 $ 100,000,000 Less: Debt discount (12,984,729 ) (5,133,761 ) Senior notes payable $ 139,810,931 $ 94,866,239 On March 23, 2022 (the “Hayfin Closing Date”), the Company and all of its subsidiaries entered into a Credit and Guaranty Agreement (the “Hayfin Credit Agreement”) with Hayfin Services LLP (“Hayfin”). The Hayfin Credit Agreement provides for a senior secured term loan facility in a principal amount of up to $175.0 million (the “Hayfin Credit Facility”), composed of (i) a term loan made on the Hayfin Closing Date in the principal amount of $150.0 million (the “Hayfin Closing Date Loan”), and (ii) a delayed draw term loan in the principal amount of $25.0 million (the “Hayfin Delayed Draw Loan” and, together with the Hayfin Closing Date Loan, the “Hayfin Loans”). The obligation of the lenders to make the Hayfin Delayed Draw Loan expires on March 22, 2023 and is subject to the satisfaction of certain conditions, including, but not limited to, the Company’s meeting certain 12-month revenue targets as set forth in the Hayfin Credit Agreement. The Hayfin Credit Facility has a maturity date of March 23, 2027 (the “Hayfin Maturity Date”), subject to acceleration pursuant to the Hayfin Credit Agreement, including upon an Event of Default (as defined in the Hayfin Credit Agreement). On the Hayfin Closing Date, the Company used $100.0 million of the Hayfin Closing Date Loan to terminate and pay in full all of the outstanding obligations under the Company’s previously existing credit facility (the “Perceptive Credit Facility”) with Perceptive Credit Holdings II, LP (“Perceptive”). The Company also used $2.0 million of the Hayfin Closing Date Loan proceeds to pay a redemption premium to Perceptive and used approximately $0.6 million of the Hayfin Closing Date Loan proceeds to pay certain fees and expenses incurred in connection with this transaction. In addition, a $1.8 million upfront fee payable to Hayfin was paid “in kind” and was added to the outstanding principal balance in accordance with the terms of the Hayfin Credit Agreement. In connection with the retirement of the Perceptive Credit Facility and all of the obligations thereunder, the Company recorded a loss on extinguishment of debt in the amount of $6.7 million, consisting of the write-off of unamortized discount related to the Perceptive indebtedness and the redemption premium paid to Perceptive. Borrowings under the Hayfin Credit Agreement bear interest, at the Company’s election, at either (a) a base rate (equal to the highest of (i) the rate of interest per annum last quoted by The Wall Street Journal as the “Prime Rate” in the United States, (ii) the federal funds rate in effect on such day plus 0.50% and (iii) adjusted Term Secured Overnight Financing Rate (“SOFR”) for a one-month tenor in effect on such day plus 1.00%), plus an applicable margin of 8.5%, or (b) adjusted Term SOFR for either a one-month or three-month tenor, as elected by the Company, and subject to a floor of 1.25%, plus an applicable margin of 9.5% (the “Applicable Margin”); provided, however, that upon, and during the continuance of, an Event of Default, the Applicable Margin shall increase by an additional 3% per annum. On the last day of each calendar month or quarter during the term of the Hayfin Credit Facility, the Company will pay accrued interest to Hayfin. The rate of interest in effect as of the Hayfin Closing Date and through June 30, 2022 was 10.75%. The Company is also permitted to pay “in kind” a portion of the interest on the Hayfin Loans for each monthly or quarterly interest period in an amount equal to 2.5% per annum, which is added to the principal amount of the outstanding debt under the Hayfin Credit Facility. From On the Hayfin Maturity Date, the Company will pay Hayfin the entire outstanding principal amount underlying the Hayfin Loans and any accrued and unpaid interest thereon, as well as an exit fee of 1.0% of the outstanding principal amount being paid. This exit fee is recorded separately as a non-current liability on the accompanying condensed consolidated balance sheet as of June 30, 2022. Prior to the Hayfin Maturity Date, there are no scheduled principal payments on the Hayfin Loans. The Company may prepay outstanding principal on the Hayfin Loans at any time and from time to time upon five All of the Company’s obligations under the Hayfin Credit Agreement are secured by a first-priority lien and security interest in substantially all of the Company’s tangible and intangible assets, including intellectual property and all of the equity interests in the Company’s subsidiaries. The Hayfin Credit Agreement contains certain representations and warranties, affirmative covenants, negative covenants and conditions that are customarily required for similar financings. The negative covenants restrict or limit the ability of the Company and its subsidiaries to, among other things and subject to certain exceptions contained in the Hayfin Credit Agreement, incur new indebtedness; create liens on assets; engage in certain fundamental corporate changes, such as mergers or acquisitions, or changes to the Company’s or its subsidiaries’ business activities; make certain Investments or Restricted Payments (each as defined in the Hayfin Credit Agreement); change its fiscal year; pay dividends; repay other certain indebtedness; engage in certain affiliate transactions; or enter into, amend or terminate any other agreements that have the impact of restricting the Company’s ability to make loan repayments under the Hayfin Credit Agreement. In addition, the Company is required (i) at all times prior to the Maturity Date to maintain a minimum cash balance of $6.0 million; and (ii) as of the last day of each fiscal quarter commencing with the fiscal quarter ended June 30, 2022, report IVIG product and related revenues for the trailing 12-month period that exceed the amounts set forth in the Hayfin Credit Agreement, which range from $75.0 million for the fiscal quarter ended June 30, 2022 to $250.0 million for the fiscal quarter ended December 31, 2026. As of June 30, 2022, the Company was in compliance with all of the covenants contained in the Hayfin Credit Agreement. As consideration for the Hayfin Credit Agreement, the Company issued to various entities affiliated with Hayfin, on the Hayfin Closing Date, warrants to purchase an aggregate of 9,103,047 shares of the Company’s common stock (the “Hayfin Warrants”). The Hayfin Warrants have an exercise price equal to $1.6478 per share, which is equal to the trailing 30-day Volume Weighted-average Price of the Company’s common stock on the business day immediately prior to the Hayfin Closing Date. The Hayfin Warrants were valued by the Company at approximately $9.6 million as of the Hayfin Closing Date and have an expiration date of March 23, 2029. As a result of the upfront fee and exit fee paid or payable to Hayfin, the expenses incurred by the Company in connection with this transaction and the value of the Hayfin Warrants, the Company recognized an aggregate discount on the Hayfin Loans in the amount of $13.4 million. The Company records debt discount as a reduction to the face amount of the debt, and the debt discount is amortized as interest expense over the life of the debt using the interest method. Based on the fair value of the Hayfin Warrants and the aggregate amount of fees and expenses associated with obtaining the Hayfin Credit Facility, the effective interest rate on the Hayfin Loans as of the Hayfin Closing Date and as of June 30, 2022 was approximately 13.0%.

STOCKHOLDERS' EQUITY

STOCKHOLDERS' EQUITY	6 Months Ended
	Jun. 30, 2022
STOCKHOLDERS' EQUITY [Abstract]
STOCKHOLDERS' EQUITY	8. STOCKHOLDERS’ EQUITY Preferred Stock The Company is currently authorized to issue up to 10 million shares of preferred stock, $0.0001, par value per share. There were no shares of preferred stock outstanding at June 30, 2022 and December 31, 2021. Common Stock As of June 30, 2022 and December 31, 2021, the Company was authorized to issue 300,000,000 shares of its common stock, $0.0001 par value per share, and 196,356,232 and 195,813,817 shares of common stock were outstanding as of June 30, 2022 and December 31, 2021, respectively. After giving effect to the 50,523,424 shares reserved for outstanding warrants and awards issued or reserved for future issuance under the Company’s equity incentive plans, as of June 30, 2022 there were 53,120,344 shares of common stock available for issuance. On September 3, 2021, the Company entered into a distribution agreement with Raymond James & Associates, Inc., as agent (“Agent”), pursuant to which the Company may offer and sell, from time to time, at its option, through or to the Agent, up to an aggregate o million of shares of the Company’s common stock (the “Distribution Agreement”). The Company intends to use any net proceeds from the sale of common stock under the Distribution Agreement for general corporate purposes, including procurement of source plasma and other $42.8 million of shares available to sell under the Distribution Agreement. On August 5, 2020, the Company entered into an open market sale agreement (as amended from time to time, the “Sale Agreement”) with Jefferies LLC (“Jefferies”), pursuant to which the Company could offer and sell, from time to time, at its option, through or to Warrants In connection with the Hayfin Credit Agreement that the Company entered into on March 23, 2022 (see Note 7), the Company issued the Hayfin Warrants to purchase 9,103,047 shares of the Company’s common stock. The Hayfin Warrants were valued at $9.6 million using the Black-Scholes option-pricing model assuming an expected term of seven years, a volatility of 68.1%, a dividend yield of 0% and a risk-free rate of interest of 2.36%. During the six months ended June 30, 2022, outstanding warrants to purchase 74,309 shares of the Company’s common stock expired in accordance with the terms of the warrants. At June 30, 2022, the Company had outstanding warrants to purchase an aggregate of 13,556,898 shares of common stock, with a weighted-average exercise price of $2.00 per share. At December 31, 2021, the Company had outstanding warrants to purchase an aggregate of 4,528,160 shares of common stock, with a weighted average exercise price of $2.82 per share and expiration dates ranging between June 2022 and December 2030. Equity Incentive Plans The fair value of stock options granted under the ADMA Biologics, Inc. 2014 Omnibus Incentive Compensation Plan, as amended and restated (the “2014 Plan”), was determined on the date of grant using the Black-Scholes option valuation model. The Black-Scholes model was developed for use in estimating the fair value of publicly traded options, which have no vesting restrictions and are fully transferable. In addition, option valuation models require the input of certain subjective assumptions including the expected stock price volatility. The stock options granted to employees and directors have characteristics significantly different from those of traded options, and changes in the subjective input assumptions can materially affect the fair value estimate. The following assumptions were used to determine the fair value of options granted during the six months ended June 30, 2022 and 2021: Six Months Ended June 30, 2022 2021 Expected term 5.5 - 6.3 years 5.5 - 6.3 years Volatility 68 % 69 % Dividend yield 0.0 0.0 Risk-free interest rate 1.72-1.73 % 0.80-1.14 % On June 21, 2022, the Company’s stockholders approved the ADMA Biologics, Inc. 2022 Compensation Plan (the “2022 Equity Plan”). Approval of the 2022 Equity Plan resulted in approximately 18 million additional shares of the Company’s common stock being reserved for future awards. During the six months ended June 30, 2022 and 2021, the Company granted options to purchase an aggregate of 1,194,032 and 1,658,050 shares of common stock, respectively, to its directors and employees. The weighted average remaining contractual life of stock options outstanding and expected to vest at June 30, 2022 is 6.5 years. The weighted average remaining contractual life of stock options exercisable at June 30, 2022 is 5.4 years. A summary of the Company’s option activity under the Company’s equity incentive plans and related information is as follows: Shares Weighted Average Exercise Price Options outstanding, vested and expected to vest at December 31, 2021 7,862,722 $ 3.93 Forfeited (19,371 ) $ 2.24 Expired (533,204 ) $ 6.78 Granted 1,194,032 $ 1.67 Options outstanding, vested and expected to vest at June 30, 2022 8,504,179 $ 3.43 Options exercisable 5,825,013 $ 4.04 As of June 30, 2022, the Company had $3.3 million of unrecognized compensation expense related to options granted under the Company’s equity incentive plans, which is expected to be recognized over a weighted-average period of 2.4 years. During the six months ended June 30, 2022 and 2021, the Company granted RSUs representing an aggregate of 1,109,266 and 542,244 shares, respectively, to certain management employees of the Company and to members of its Board of Directors . These RSUs generally vest annually over a period of four years for employees and semi-annually over a period of one year for directors. Du ring the six months ended June 30, 2022, there were 812,016 shares of common stock which vested in connection with grants of RSUs, including 254,745 milestone-based RSUs that vested in connection with the refinancing of the Company’s senior credit facility (see Note 7) and 382,117 milestone-based RSUs that vested in connection with the Company achieving a targeted gross margin for its BIVIGAM product during the six months ended June 30, 2022. With respect to the vested RSUs, 269,601 shares valued at approximately $0.4 million were withheld by the Company to cover employees’ tax liabilities. These shares have been retired by the Company and were no longer outstanding as of A summary of the Company’s unvested RSU activity and related information is as follows: Shares Weighted Average Grant Date Fair Value Balance at December 31, 2021 4,485,133 $ 1.34 Granted 1,109,266 $ 1.68 Vested (812,016 ) $ 1.41 Forfeited (40,000 ) $ 1.22 Balance at June 30, 2022 4,742,383 $ 1.41 As of June 30, 2022, the Company had $5.1 million of unrecognized compensation expense related to unvested RSUs granted under the Company’s equity incentive plans, which is expected to be recognized over a weighted-average period of 2.7 years. Total stock-based compensation expense for all awards granted under the Company’s equity incentive plans for the three and six months ended June 30, 2022 and 2021 is as follows: Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 Research and development $ 4,898 $ 42,479 $ 9,569 $ 147,706 Plasma center operating expenses 19,615 13,637 40,667 24,455 Selling, general and administrative 1,068,215 665,836 2,585,817 1,254,327 Cost of product revenue 98,319 83,237 196,382 160,098 Total stock-based compensation expense $ 1,191,047 $ 805,189 $ 2,832,435 $ 1,586,586

RELATED PARTY TRANSACTIONS

RELATED PARTY TRANSACTIONS	6 Months Ended
	Jun. 30, 2022
RELATED PARTY TRANSACTIONS [Abstract]
RELATED PARTY TRANSACTIONS	9. RELATED PARTY TRANSACTIONS The Company leases an office building and equipment from Areth, LLC (“Areth”) pursuant to an agreement for services effective as of January 1, 2016, as amended from time to time. Rent expense for the six months ended June 30, 2022 and 2021 amounted to $60,000. Areth is a company controlled by Dr. Jerrold B. Grossman, the Vice Chairman of the Company’s Board of Directors, and Adam S. Grossman, the Company’s President and Chief Executive Officer. The Company also reimburses Areth for office and building-related (common area) expenses, equipment and certain other operational expenses, which were not material to the condensed consolidated financial statements for the three and six months ended June 30, 2022 and 2021. During the six months ended June 30, 2022 and 2021, the Company purchased certain specialized medical equipment and services related to the Company’s plasma collection centers, as well as personal protective equipment, from GenesisBPS and its affiliates (“Genesis”), aggregating to $0.1 million. Genesis is owned by Dr. Grossman and Adam Grossman. See Note 7 for a discussion of the Company’s former credit facility and related transactions with Perceptive, a holder of more than 5% of the Company’s common stock during the six months ended June 30, 2022.

COMMITMENTS AND CONTINGENCIES

COMMITMENTS AND CONTINGENCIES	6 Months Ended
	Jun. 30, 2022
COMMITMENTS AND CONTINGENCIES [Abstract]
COMMITMENTS AND CONTINGENCIES	10. COMMITMENTS AND CONTINGENCIES General Legal Matters From time to time, the Company is or may become subject to certain legal proceedings and claims arising in connection with the normal course of its business. Management does not expect that the outcome of any such claims or actions will have a material effect on the Company’s liquidity, results of operations or financial condition. COVID-19 Pandemic The Company continues to monitor the ongoing developments related to the COVID-19 pandemic, including the emergence of the Delta and Omicron variants and other resistant strains of the coronavirus, and its impacts to the Company’s commercial and manufacturing operations and plasma collection facilities, including collections of source plasma, procurement of raw materials and packaging materials, a portion of which are sourced internationally, and the testing of finished drug product that is required prior to its availability for commercial sale. A substantial portion of such testing has historically been performed by contract laboratories outside the United States. Due to a combination of previous state and local “shelter-in-place” orders, as well as government stimulus packages, persisting social distancing measures and varying roll-outs of vaccinations by state, the Company has experienced lower than normal donor collections at its FDA approved plasma collection centers. The Company was also subject to delays in shipments of source plasma from its contracted third-party suppliers, as well as delays in deliveries for personal protective equipment, reagents and other non-plasma raw materials and supplies used in the manufacture and distribution of its products. In addition, the Company is subject to supply chain delays as a result of certain of its suppliers diverting significant resources towards the rapid development and distribution of COVID-19 vaccines and, as a result, the Company has elected to carry more raw materials inventory than it has in the past. The COVID-19 pandemic has also impacted, to a certain degree, the Company’s customer engagement initiatives, whereby ADMA’s sales and medical affairs field personnel have faced difficulties communicating directly with physicians and other healthcare professionals, as well as the cancellation or postponement of a number of key scientific and medical meetings, further limiting the Company’s ability to communicate with potential customers. The Company has implemented a comprehensive suite of virtual engagement initiatives; however, clinician engagement has been reduced due to rapidly evolving COVID-19 priorities at U.S. medical centers. The pandemic could also impact the Company’s ability to interact with the FDA or other regulatory authorities and may result in delays in the conduct of inspections or review of pending applications or submissions. Although the Company received several FDA approvals and two FDA inspections of the Boca Facility were completed during the year ended December 31, 2021, no assurances can be provided as to the timing for completion of any other regulatory submissions or applications that may be impacted by restrictions related to COVID-19. During the six months ended June 30, 2022 and 2021, revenue attributable to international customers was approximately 7% and 14%, respectively, of the Company’s total revenues. As the Company seeks to grow this aspect of its business, it may also be subject to the impacts of the COVID-19 pandemic in locations outside the United States. Notwithstanding the foregoing, the COVID-19 pandemic to date has not had a material impact on the Company’s financial condition or results of operations, and the Company does not believe that its production operations at the Boca Facility, the Company’s contract fill/finishers or its plasma collection facilities have been significantly impacted by the COVID-19 pandemic. As a result, the Company does not anticipate and has not experienced any material impairments with respect to any of its long-lived assets, including the Company’s property and equipment, goodwill or intangible assets. Although the COVID-19 pandemic has not, to date, materially adversely impacted the Company’s capital and financial resources, because the Company is unable to determine the ultimate severity or duration of the COVID-19 pandemic or other pandemics or their long-term effects on, among other things, the global, national or local economies, the capital and credit markets or the Company’s workforce, customers or our suppliers, at this time the Company is unable to predict whether COVID-19 or other pandemics will have a material adverse impact on the Company’s business, financial condition, liquidity and results of operations. Vendor Commitments Pursuant to the terms of a plasma purchase agreement with BPC dated as of November 17, 2011 (the “2011 Plasma Purchase Agreement”), the Company agreed to purchase from BPC an annual minimum volume of source plasma containing antibodies to RSV to be used in the manufacture of ASCENIV. The Company must purchase a to-be-determined and agreed upon annual minimum volume from BPC, but may also collect high-titer RSV plasma from up to five wholly-owned ADMA plasma collection facilities. During 2015, the Company and BPC amended the 2011 Plasma Purchase Agreement to allow the Company the ability to collect its raw material RSV high-titer plasma from other third-party collection organizations, thus allowing the Company to expand its reach for raw material supply as it executes its commercialization plans for ASCENIV. As part of the closing of the Biotest Transaction, the parties amended the 2011 Plasma Purchase Agreement to extend the initial term through the ten-year anniversary of the closing date of the Biotest Transaction. Unless terminated earlier, the 2011 Plasma Purchase Agreement expires in June 2027, after which it may be renewed for two additional five-year periods if agreed to by the parties. On December 10, 2018, BPC assigned its rights and obligations under the 2011 Plasma Purchase Agreement to Grifols Worldwide Operations Limited (“Grifols”) as its successor-in-interest, effective January 1, 2019. On January 1, 2019, Grifols and the Company entered into an additional amendment to the 2011 Plasma Purchase Agreement for the purchase of source plasma containing antibodies to RSV from Grifols. Pursuant to this amendment, until January 1, 2022, the Company could purchase RSV plasma from Grifols from the two plasma collection centers that were transferred to BPC on January 1, 2019 at a price equal to cost plus five percent (5%) (without any additional increase due to inflation). Effective January 1, 2022, RSV plasma purchased from these two plasma collection centers are subject to the pricing terms in effect for RSV plasma purchased from other plasma collection centers owned by Grifols. On June 6, 2017, the Company and BPC entered into a Plasma Supply Agreement pursuant to which BPC supplies, on an exclusive basis subject to certain exceptions, to ADMA BioManufacturing an annual minimum volume of hyperimmune plasma that contain antibodies to the Hepatitis B virus for the manufacture of Nabi-HB. The Plasma Supply Agreement has a 10-year term. On July 19, 2018, the Company and BPC entered into an amendment to the Plasma Supply Agreement to provide, among other things, that in the event BPC elects not to supply in excess of ADMA BioManufacturing’s specified amount of Hepatitis B plasma and ADMA BioManufacturing is unable to secure Hepatitis B plasma from a third party at a price that is within a low double- digit percentage of the price that ADMA BioManufacturing pays to BPC, then BPC shall reimburse ADMA BioManufacturing for the difference in price ADMA BioManufacturing incurs. On December 10, 2018, BPC assigned its rights and obligations under the Plasma Supply Agreement to Grifols, effective January 1, 2019. On June 6, 2017, the Company and BPC entered into a Plasma Purchase Agreement (the “2017 Plasma Purchase Agreement”), pursuant to which ADMA BioManufacturing purchases normal source plasma (“NSP”) from BPC at agreed upon annual quantities and prices. The 2017 Plasma Purchase Agreement has an initial term of five years after which the 2017 Plasma Purchase Agreement may be renewed for additional two terms of two years each upon the mutual written consent of the parties. On July 19, 2018, the Company and BPC entered into an amendment to the 2017 Plasma Purchase Agreement to, among other things, provide agreed upon amounts of normal source plasma to be supplied by BPC to ADMA BioManufacturing in calendar year 2019 at a specified price per liter, provided that ADMA BioManufacturing delivers a valid purchase order to BPC. Additionally, pursuant to the amendment to the 2017 Plasma Purchase Agreement, BPC agreed that, for calendar years 2020 and 2021, it shall supply no less than a high double-digit percentage of ADMA BioManufacturing’s requested NSP amounts, provided that such requested NSP amounts are within an agreed range, at a price per liter to be mutually determined. Furthermore, pursuant to the amendment to the 2017 Plasma Purchase Agreement, in the event BPC fails to supply ADMA BioManufacturing with at least a high double-digit percentage of ADMA BioManufacturing’s requested NSP amounts, BPC shall promptly reimburse ADMA BioManufacturing the difference in price ADMA BioManufacturing incurs due to BPC’s election not to supply NSP to ADMA BioManufacturing in such amounts as requested. On December 10, 2018, BPC assigned its rights and obligations under the Plasma Purchase Agreement to Grifols, effective January 1, 2019. Effective as of May 12, 2021, the Company and Grifols amended the foregoing 2017 Plasma Purchase Agreement whereby, among other things, the term of the agreement was extended through December 31, 2022, while certain historical provisions were deleted. In order to maintain a reliable supply of raw material plasma thereafter, the Company has executed additional agreements with multiple third-party suppliers of NSP to supplement the 2017 Plasma Purchase Agreement. The Company has also increased its number of planned plasma collection center buildouts such that the Company expects to have ten FDA-approved plasma collection centers in operation by the end of 2023, while also continuing to increase its plasma collection capabilities at its ADMA BioCenters plasma collection centers business segment. The Company purchases substantially all of its raw material plasma from Grifols. For the six months ended June 30, 2022, plasma purchases from Grifols totaled $22.8 million, or approximately 66% of the Company’s total inventory purchases. For the six months ended June 30, 2021, plasma purchases from Grifols totaled approximately $17.5 million, representing approximately 67% of the Company’s total inventory purchases. Post-Marketing Commitments In connection with the approval of the BLA for BIVIGAM, on December 19, 2012 Biotest committed to perform two additional post-marketing studies, a pediatric study to evaluate the efficacy and safety of BIVIGAM in children and adolescents, and a post-authorization safety study to further assess the potential risk of hypotension and hepatic and renal impairment in BIVIGAM-treated patients with primary humoral immunodeficiency. These studies are still pending completion. ADMA has assumed the remaining obligations, and the costs of the studies will be expensed as incurred as research and development expenses. The Company currently expects to incur expenses of approximately $3.0 million to $4.0 million to complete these studies, with both studies to be completed by June of 2023. In connection with the FDA’s approval of ASCENIV on April 1, 2019, the Company is required to perform a pediatric study to evaluate the safety and efficacy of ASCENIV in children and adolescents. The Company expects to incur expenses of approximately $2 million to complete this study, which is required to be completed by June of 2023. Employment Contracts The Company has entered into employment agreements with Mr. Grossman and with Brian Lenz, its Executive Vice President, Chief Financial Officer and General Manager, ADMA BioCenters. Other Commitments On September 28, 2021, following the approval of the Company’s Board of Directors upon recommendation of the Compensation Committee of the Board of Directors, and in consultation with an independent compensation consultant, the Company implemented a retention incentive program, consisting of cash payments and awards of RSUs (see Note 8), to the Company’s management, including Mr. Grossman and Mr. Lenz, and to certain other employees. The purpose of the retention program is to promote and ensure business continuity and provide an incentive to the Company’s executive management and certain other employees considering the operational challenges presented by the ongoing COVID -19 pandemic and the competitive work environment in which the Company operates as an FDA regulated manufacturer of specialized biologic therapies. The retention awards were granted considering the nationwide labor shortages and the increased employee turnover rates that the Company, its pharmaceutical peers and other companies outside of the Company’s industry have reported experiencing. The cash portion of the retention program consists of two tranches. The first tranche was paid to employees on September 30, 2021 in the amount of $1.3 million, and the second tranche aggregating to approximately $1.3 million was paid on June 15, 2022. Based on the terms of the retention agreements the Company entered into with each applicable executive and employee, approximately $0.8 million of each tranche is being recognized over the retention service period, which began on October 1, 2021 and ends on December 31, 2022, with the remainder having been recognized as expense when paid. In the normal course of business, the Company enters into contracts that contain a variety of indemnifications with its employees, licensors, suppliers and service providers. Further, the Company indemnifies its directors and officers who are, or were, serving at the Company’s request in such capacities. The Company’s maximum exposure under these arrangements is unknown as of June 30, 2022. The Company does not anticipate recognizing any significant losses relating to these arrangements.

SEGMENTS

SEGMENTS	6 Months Ended
	Jun. 30, 2022
SEGMENTS [Abstract]
SEGMENTS	11. SEGMENTS The Company is engaged in the manufacture, marketing and development of specialty plasma-derived biologics. The Company’s ADMA BioManufacturing segment reflects the Company’s immunoglobulin manufacturing, commercial and development operations in Boca Raton, FL, acquired on June 6, 2017 (see Note 1). The Plasma Collection Centers segment as of June 30, 2022 consists of ten plasma collection facilities located throughout the U.S., six of which hold FDA licenses, with two additional plasma collection centers in operation and collecting plasma and the remaining two facilities under construction Summarized financial information concerning reportable segments is shown in the following tables: Three Months Ended June 30, 2022 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 32,120,119 $ 1,749,179 $ 35,709 $ 33,905,007 Cost of product revenue 24,287,122 1,848,492 - 26,135,614 Loss from operations (445,248 ) (4,020,799 ) (4,708,692 ) (9,174,739 ) Interest and other expense, net (17,796 ) (336 ) (4,572,035 ) (4,590,167 ) Net loss (463,044 ) (4,021,135 ) (9,280,727 ) (13,764,906 ) Total assets 220,052,465 34,078,909 42,800,955 296,932,329 Depreciation and amortization expense 1,159,732 564,396 155 1,724,283 Three Months Ended June 30, 2021 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 16,347,880 $ 1,447,001 $ 35,709 $ 17,830,590 Cost of product revenue 17,382,292 1,450,332 - 18,832,624 Loss from operations (8,337,405 ) (2,794,219 ) (4,449,608 ) (15,581,232 ) Interest and other expense, net (78,793 ) (366 ) (3,244,912 ) (3,324,071 ) Net loss (8,416,198 ) (2,794,585 ) (7,694,520 ) (18,905,303 ) Total assets 169,799,509 20,593,411 42,420,872 232,813,792 Depreciation and amortization expense 1,055,537 268,927 1,530 1,325,994 Six Months Ended June 30, 2022 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 57,848,744 $ 5,087,939 $ 71,417 $ 63,008,100 Cost of product revenue 46,500,902 5,075,758 - 51,576,660 Loss from operations (4,720,538 ) (7,883,894 ) (11,385,373 ) (23,989,805 ) Interest and other expense, net (67,062 ) (1,066 ) (8,044,889 ) (8,113,017 ) Loss on extinguishment of debt - - (6,669,941 ) (6,669,941 ) Net loss (4,787,600 ) (7,884,960 ) (26,100,203 ) (38,772,763 ) Capital expenditures 2,584,906 4,197,263 - 6,782,169 Depreciation and amortization expense 2,271,683 1,041,899 918 3,314,500 Six Months Ended June 30, 2021 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 29,768,923 $ 4,038,868 $ 71,417 $ 33,879,208 Cost of product revenue 32,832,049 3,770,697 - 36,602,746 Loss from operations (17,843,093 ) (4,765,060 ) (8,137,328 ) (30,745,481 ) Interest and other expense, net (100,307 ) (750 ) (6,438,706 ) (6,539,763 ) Net loss (17,943,400 ) (4,765,810 ) (14,576,034 ) (37,285,244 ) Capital expenditures 2,725,432 4,321,303 - 7,046,735 Depreciation and amortization expense 2,065,307 486,918 3,397 2,555,622 Net revenues according to geographic area, based on the location of where the product is shipped, is as follows: Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 United States $ 31,274,844 $ 15,424,839 $ 58,590,995 $ 29,102,848 International 2,630,163 2,405,751 4,417,105 4,776,360 Total revenues $ 33,905,007 $ 17,830,590 $ 63,008,100 $ 33,879,208

LEASE OBLIGATIONS

LEASE OBLIGATIONS	6 Months Ended
	Jun. 30, 2022
LEASE OBLIGATIONS [Abstract]
LEASE OBLIGATIONS	12. LEASE OBLIGATIONS The Company leases certain properties and equipment for its ADMA BioCenters and ADMA BioManufacturing subsidiaries, which leases provide the right to use the underlying assets and require lease payments through the respective lease terms which expire at various dates through 2032. The Company’s lease agreements do not contain any material residual value guarantees or material restrictive covenants. The Company determines if an arrangement is an operating lease at inception. Leases with an initial term of 12 months or less are not recorded on the balance sheet. All other leases are recorded on the balance sheet with assets representing the right to use the underlying asset for the lease term and lease liabilities representing the obligation to make lease payments arising from the lease. Right-to-use assets and lease liabilities are recognized at the lease commencement date based on the present value of lease payments over the lease term and include options to extend or terminate the lease when they are reasonably certain to be exercised. The present value of the lease payments is determined using the Company’s incremental borrowing rate of 13%. The Company’s lease expense is recognized on a straight-line basis over the lease term and is reflected in Plasma center operating expenses and Selling, general and administrative expenses. Aggregate lease expense for the Company’s leases for the three months ended June 30, 2022 and 2021 was approximately $0.5 million and $0.4 million, respectively. Aggregate lease expense for the Company’s leases for the six months ended June 30, 2022 and 2021 was approximately $0.9 million and $0.6 million, respectively. Cash paid for the Company’s leases for the three months ended June 30, 2022 and 2021 was approximately $0.4 million and $0.6 million, respectively. Cash paid for the Company’s leases for the six months ended June 30, 2022 and 2021 was approximately $0.8 million. Including a finance lease the Company entered into in June 2018, the Company has aggregate lease liabilities of $11.5 million and $8.1 million as of June 30, 2022 and December 31, 2021, respectively, which are comprised primarily of the leases for the Company’s plasma collection centers and a warehouse lease for raw material storage related to the Company’s immunoglobulin manufacturing operations. The Company’s operating leases have a weighted average remaining term of 9.1 years. Scheduled payments under the Company’s lease obligations are as follows: Remainder of 2022 $ 945,228 Year ended December 31, 2023 2,247,057 2024 2,223,314 2025 2,246,432 2026 1,996,036 2027 2,040,690 Thereafter 8,238,571 Total payments 19,937,328 Less: imputed interest (8,486,760 ) Current portion (579,661 ) Balance at June 30, 2022 $ 10,870,907

SUPPLEMENTAL DISCLOSURE OF CASH

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION	6 Months Ended
	Jun. 30, 2022
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION [Abstract]
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION	13. SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION Supplemental cash flow information for the six months ended June 30, 2022 and 2021 is as follows: 2022 2021 SUPPLEMENTAL CASH FLOW INFORMATION: Cash paid for interest $ 5,989,332 $ 5,534,279 Noncash Financing and Investing Activities: Equipment acquired reflected in accounts payable and accrued liabilities $ 1,164,319 $ 1,005,546 Right-to-use assets in exchange for lease obligations $ 3,660,890 $ 2,844,875 Warrants issued in connection with notes payable $ 9,569,604 $ -

SUMMARY OF SIGNIFICANT ACCOUN_2

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)	6 Months Ended
	Jun. 30, 2022
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]
Basis of Presentation	Basis of Presentation The accompanying unaudited condensed consolidated financial statements have been prepared in conformity with accounting principles generally accepted in the United States of America (“U.S. GAAP”) for interim financial information. Any reference in these notes to applicable guidance is meant to refer to U.S. GAAP as found in the Accounting Standards Codification (“ASC”) and Accounting Standards Updates (“ASU”) of the Financial Accounting Standards Board (the “FASB”). The accompanying unaudited condensed consolidated financial statements should be read in conjunction with the annual audited consolidated financial statements and notes thereto as of and for the year ended December 31, 2021 included in the Company’s Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (the “SEC”) on March 24, 2022. The accompanying consolidated balance sheet as of December 31, 2021 was derived from the audited financial statements as of and for the year ended December 31, 2021. These condensed consolidated interim financial statements have been prepared in accordance with the instructions to Form 10-Q and Article 8 of Regulation S-X, and therefore omit or condense certain footnotes and other information normally included in complete consolidated financial statements prepared in accordance with U.S. GAAP. All intercompany balances and transactions have been eliminated in consolidation. In the opinion of management, the accompanying unaudited condensed consolidated financial statements include all normal and recurring adjustments (which consist primarily of accruals, estimates and assumptions that impact the financial statements) considered necessary to present fairly the Company’s financial position as of June 30, 2022, its results of operations and changes in stockholders’ equity for the three and six months ended June 30, 2022 and 2021 and cash flows for the six months ended June 30, 2022 and 2021. During the three and six months ended June 30
Use of Estimates	Use of Estimates The preparation of financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. Significant estimates include rebates and chargebacks deducted from gross revenues, the realizable value of accounts receivable, valuation of inventory, assumptions used in projecting future liquidity and capital requirements, assumptions used in the fair value of awards granted under the Company’s equity incentive plans and warrants issued in connection with the issuance of notes payable and the valuation allowance for the Company’s deferred tax assets.
Fair Value of Financial Instruments	Fair Value of Financial Instruments The carrying amounts of certain of the Company’s financial instruments, including cash and cash equivalents, accounts receivable and accounts payable, are shown at cost which approximates fair value due to the short-term nature of these instruments. The debt outstanding under the Company’s senior secured term loan (see Note 7) approximates fair value due to the variable interest rate on this debt.
Accounts Receivable	Accounts Receivable Accounts receivable is reported at realizable value, net of allowances for contractual credits and doubtful accounts in the amount of $0.1 million and $0.2 million at June 30 The Company extends credit to its customers based upon an evaluation of each customer’s financial condition and credit history. Evaluations of the financial condition and associated credit risk of customers are performed on an ongoing basis. June 30
Inventories	Inventories Raw materials inventory consists of various materials purchased from suppliers, including normal source plasma, used in the production of the Company’s products. Work-in-process and finished goods inventories (see Note 3) reflect the cost of raw materials as well as costs for direct and indirect labor, primarily salaries, wages and benefits for applicable employees, as well as an allocation of overhead costs related to the Boca Facility including utilities, property taxes, general repairs and maintenance, consumable supplies and depreciation. The allocation of Boca Facility overhead to inventory is generally based upon the estimated square footage of the Boca Facility that is used in the production of the Company’s products relative to the total square footage of the facility. Inventories, including plasma intended for resale and plasma intended for internal use in the Company’s manufacturing, commercialization or research and development activities, are carried at the lower of cost or net realizable value determined by the first-in, first-out method. Net realizable value is generally determined based upon the consideration the Company expects to receive when the inventory is sold, less costs to deliver the inventory to the recipient. The estimates for net realizable value of inventory are based on contractual terms or upon historical experience and certain other assumptions, and the Company believes that such assumptions are reasonable. Inventory is periodically reviewed to ensure that its carrying value does not exceed its net realizable value, and adjustments are recorded to write down such inventory, with a corresponding charge to cost of product revenue, when the carrying value or historical cost exceeds its estimated net realizable value. In addition, costs associated with the production of conformance or engineering lots that would not qualify as immediately available for commercial sale are charged to cost of product revenue and not capitalized into inventory.
Goodwill	Goodwill Goodwill represents the excess of purchase price over the fair value of net assets acquired by the Company. Goodwill at June 30, 2022 and December 31, 2021 was $3.5 million. All of the Company’s goodwill is attributable to its ADMA BioManufacturing business segment and is related to the Biotest Transaction. Goodwill is not amortized but is assessed for impairment on an annual basis or more frequently if impairment indicators exist. The Company has the option to perform a qualitative assessment of goodwill to determine whether it is more likely than not that the fair value of its reporting unit is less than its carrying amount, including goodwill and other intangible assets. If the Company concludes that this is the case, then it must perform a goodwill impairment test by comparing the fair value of the reporting unit to its carrying value. An impairment charge is recorded to the extent the reporting unit’s carrying value exceeds its fair value, not to exceed the total amount of goodwill allocated to that reporting unit. The Company performs its annual goodwill impairment test as of October 1 of each year. The Company’s annual goodwill impairment test as of October 1, 2021 did not result in a goodwill impairment charge, and the Company did not record any impairment charges related to goodwill for the six months ended June 30, 2022 and 2021.
Impairment of Long-Lived Assets	Impairment of Long-Lived Assets The Company assesses the recoverability of its long-lived assets, which include property and equipment and finite-lived intangible assets, whenever significant events or changes in circumstances indicate impairment may have occurred. If indicators of impairment exist, projected future undiscounted cash flows associated with the asset are compared to its carrying amount to determine whether the asset’s carrying value is recoverable. Any resulting impairment is recorded as a reduction in the carrying value of the related asset in excess of fair value and a charge to operating results. For the six months ended June 30
Revenue Recognition	Revenue Recognition Revenues for the three and six months ended June 30 Product revenue is recognized when the customer is deemed to have control over the product. Control is determined based on when the product is shipped or delivered and title passes to the customer. Revenue is recorded in an amount that reflects the consideration the Company expects to receive in exchange. Revenue from the sale of the Company’s immunoglobulin products is recognized when the product reaches the customer’s destination, and is recorded net of estimated rebates, price protection arrangements and customer incentives, including prompt pay discounts, wholesaler chargebacks and other wholesaler fees. These estimates are based on historical experience and certain other assumptions, and the Company believes that such estimates are reasonable. For revenues associated with contract manufacturing and the sale of intermediates, control transfers to the customer and the performance obligation is satisfied when the customer takes possession of the product from the Boca Facility or from a third-party warehouse that is utilized by the Company. Product revenues from the sale of human plasma collected at the Company’s plasma collection centers are recognized at the time control of the product has been transferred to the customer, which generally occurs at the time of shipment. Product revenues are recognized at the time of delivery if the Company retains control of the product during shipment. For the six months ended June 30 June 30
Cost of Product Revenue	Cost of Product Revenue Cost of product revenue includes costs associated with the manufacture of the Company’s FDA approved products, intermediates and the sale of human source plasma, as well as expenses related to conformance batch production, process development and scientific and technical operations when these operations are attributable to marketed products. When the activities of these operations are attributable to new products in development, the expenses are classified as research and development expenses.
Loss Per Common Share	Loss Per Common Share Basic loss per common share is computed by dividing net loss attributable to common stockholders by the weighted average number of shares of common stock outstanding during the period. Diluted loss per common share is calculated by dividing net loss attributable to common stockholders, as adjusted for the effect of dilutive securities, if any, by the weighted average number of shares of common stock and dilutive common stock outstanding during the period. Potentially dilutive common stock includes the shares of common stock issuable upon the exercise of outstanding stock options and warrants, using the treasury stock method, as well as Restricted Stock Units (“RSUs”). Potentially dilutive common stock is excluded from the diluted loss per common share computation to the extent that it would be anti-dilutive. As a result, no potentially dilutive securities are included in the computation of any of the accompanying diluted loss per share amounts in the accompanying condensed consolidated financial statements as the Company reported a net loss for all periods presented. For the six months ended June 30 , 2022 and 2021, the following securities were excluded from the calculation of diluted loss per common share because of their anti-dilutive effects: For the Six Months Ended June 30, 2022 2021 Stock options 8,504,179 7,783,029 Restricted Stock Units 4,742,383 686,133 Warrants 13,556,898 4,528,160 26,803,460 12,997,322
Stock-Based Compensation	Stock-Based Compensation The Company follows recognized accounting guidance which requires all equity-based payments, including grants of stock options, to be recognized in the statement of operations as compensation expense based on their fair values at the date of grant. Compensation expense related to awards to employees and directors with service-based vesting conditions is recognized on a straight-line basis over the associated vesting period of the award based on the grant date fair value of the award. Stock options granted under the Company’s equity incentive plans generally have a four-year vesting period and a term of 10 years. Pursuant to ASU No. 2016-09, Improvements to Employee Share-Based Payment Accounting (Topic 718)
Income Taxes	Income Taxes The Company recognizes deferred tax assets and liabilities for the expected future tax consequences of events that have been included in the consolidated financial statements or its tax returns. Under this method, deferred tax assets and liabilities are recognized for the temporary differences between the tax bases of assets and liabilities and their respective financial reporting amounts at enacted tax rates in effect for the years in which the temporary differences are expected to reverse. The Company records a valuation allowance on its deferred tax assets if it is more likely than not that the Company will not generate sufficient taxable income to utilize its deferred tax assets. The Company is subject to income tax examinations by major taxing authorities for all tax years since 2017 and for previous periods as it relates to the Company’s net operating loss carryforwards. In accordance with U.S. GAAP, the Company is required to determine whether a tax position of the Company is more likely than not to be sustained upon examination by the applicable taxing authority, including resolution of any related appeals or litigation processes, based on the technical merits of the position. The tax benefit to be recognized is measured as the largest amount of benefit that is greater than 50% likely of being realized upon ultimate settlement. Derecognition of a tax benefit previously recognized could result in the Company recording a tax liability that would reduce net assets. Based on its analysis, the Company has determined that it has not incurred any liability for unrecognized tax benefits as of June 30 no adjustments for uncertain tax positions.

SUMMARY OF SIGNIFICANT ACCOUN_3

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)	6 Months Ended
	Jun. 30, 2022
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES [Abstract]
Calculation of Diluted Loss Per Common Share	For the six months ended June 30 , 2022 and 2021, the following securities were excluded from the calculation of diluted loss per common share because of their anti-dilutive effects: For the Six Months Ended June 30, 2022 2021 Stock options 8,504,179 7,783,029 Restricted Stock Units 4,742,383 686,133 Warrants 13,556,898 4,528,160 26,803,460 12,997,322

INVENTORIES (Tables)

INVENTORIES (Tables)	6 Months Ended
	Jun. 30, 2022
INVENTORIES [Abstract]
Components of Inventory	The following table provides the components of inventories: June 30, 2022 December 31, 2021 Raw materials $ 38,321,843 $ 36,755,720 Work-in-process 51,136,409 58,968,535 Finished goods 56,617,207 28,999,836 Total inventories $ 146,075,459 $ 124,724,091

INTANGIBLE ASSETS (Tables)

INTANGIBLE ASSETS (Tables)	6 Months Ended
	Jun. 30, 2022
INTANGIBLE ASSETS [Abstract]
Schedule of Intangible Assets	Intangible assets at June 30, 2022 and December 31, 2021 consist of the following: June 30, 2022 December 31, 2021 Cost Accumulated Amortization Net Cost Accumulated Amortization Net Trademark and other intangible rights related to Nabi-HB $ 4,100,046 $ 2,977,415 $ 1,122,631 $ 4,100,046 $ 2,684,554 $ 1,415,492 Rights to intermediates 907,421 658,960 248,461 907,421 594,145 313,276 $ 5,007,467 $ 3,636,375 $ 1,371,092 $ 5,007,467 $ 3,278,699 $ 1,728,768
Intangible Asset Future Aggregate Amortization Expense	All of the Company’s intangible assets were acquired in the Biotest Transaction. Amortization expense related to these intangible assets was $0.4 million for the six months ended June 30, 2022 and 2021 and $0.2 million for the three months ended June 30, 2022 and 2021. Estimated future aggregate amortization expense is expected to be as follows: Remainder of 2022 $ 357,676 2023 715,352 2024 298,064

PROPERTY AND EQUIPMENT (Tables)

PROPERTY AND EQUIPMENT (Tables)	6 Months Ended
	Jun. 30, 2022
PROPERTY AND EQUIPMENT [Abstract]
Property and Equipment	Property and equipment and related accumulated depreciation are summarized as follows: June 30, 2022 December 31, 2021 Manufacturing and laboratory equipment $ 17,919,714 $ 16,702,991 Office equipment and computer software 5,133,876 4,082,462 Furniture and fixtures 4,364,091 3,389,140 Construction in process 4,830,287 5,496,222 Leasehold improvements 15,492,458 11,129,639 Land 4,339,441 4,339,441 Buildings and building improvements 19,096,164 19,067,032 71,176,031 64,206,927 Less: Accumulated depreciation (16,224,764 ) (13,271,853 ) Total property, plant and equipment, net $ 54,951,267 $ 50,935,074

ACCRUED EXPENSES AND OTHER CU_2

ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Tables)	6 Months Ended
	Jun. 30, 2022
ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES [Abstract]
Accrued Expenses and Other Current Liabilities	Accrued expenses and other current liabilities at June 30, 2022 and December 31, 2021 are as follows: June 30, 2022 December 31, 2021 Accrued rebates $ 7,764,200 $ 5,040,200 Accrued distribution fees 1,850,105 4,739,651 Accrued incentives 1,951,768 4,066,109 Accrued testing 344,892 1,189,970 Accrued payroll 1,019,912 1,167,072 Other 3,030,193 1,011,986 Total accrued expenses and other current liabilities $ 15,961,070 $ 17,214,988

DEBT (Tables)

DEBT (Tables)	6 Months Ended
	Jun. 30, 2022
DEBT [Abstract]
Summary of Outstanding Senior Notes Payable	A summary of outstanding senior notes payable is as follows: June 30, 2022 December 31, 2021 Notes payable $ 152,795,660 $ 100,000,000 Less: Debt discount (12,984,729 ) (5,133,761 ) Senior notes payable $ 139,810,931 $ 94,866,239

STOCKHOLDERS EQUITY (Tables)

STOCKHOLDERS EQUITY (Tables)	6 Months Ended
	Jun. 30, 2022
STOCKHOLDERS' EQUITY [Abstract]
Schedule of Assumptions	The following assumptions were used to determine the fair value of options granted during the six months ended June 30, 2022 and 2021: Six Months Ended June 30, 2022 2021 Expected term 5.5 - 6.3 years 5.5 - 6.3 years Volatility 68 % 69 % Dividend yield 0.0 0.0 Risk-free interest rate 1.72-1.73 % 0.80-1.14 %
Schedule of Option Activity	A summary of the Company’s option activity under the Company’s equity incentive plans and related information is as follows: Shares Weighted Average Exercise Price Options outstanding, vested and expected to vest at December 31, 2021 7,862,722 $ 3.93 Forfeited (19,371 ) $ 2.24 Expired (533,204 ) $ 6.78 Granted 1,194,032 $ 1.67 Options outstanding, vested and expected to vest at June 30, 2022 8,504,179 $ 3.43 Options exercisable 5,825,013 $ 4.04
Schedule of Unvested RSU Activity	A summary of the Company’s unvested RSU activity and related information is as follows: Shares Weighted Average Grant Date Fair Value Balance at December 31, 2021 4,485,133 $ 1.34 Granted 1,109,266 $ 1.68 Vested (812,016 ) $ 1.41 Forfeited (40,000 ) $ 1.22 Balance at June 30, 2022 4,742,383 $ 1.41
Schedule of Stock-Based Compensation Expense	Total stock-based compensation expense for all awards granted under the Company’s equity incentive plans for the three and six months ended June 30, 2022 and 2021 is as follows: Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 Research and development $ 4,898 $ 42,479 $ 9,569 $ 147,706 Plasma center operating expenses 19,615 13,637 40,667 24,455 Selling, general and administrative 1,068,215 665,836 2,585,817 1,254,327 Cost of product revenue 98,319 83,237 196,382 160,098 Total stock-based compensation expense $ 1,191,047 $ 805,189 $ 2,832,435 $ 1,586,586

SEGMENTS (Tables)

SEGMENTS (Tables)	6 Months Ended
	Jun. 30, 2022
SEGMENTS [Abstract]
Summarized Financial Information Concerning Reportable Segments	Summarized financial information concerning reportable segments is shown in the following tables: Three Months Ended June 30, 2022 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 32,120,119 $ 1,749,179 $ 35,709 $ 33,905,007 Cost of product revenue 24,287,122 1,848,492 - 26,135,614 Loss from operations (445,248 ) (4,020,799 ) (4,708,692 ) (9,174,739 ) Interest and other expense, net (17,796 ) (336 ) (4,572,035 ) (4,590,167 ) Net loss (463,044 ) (4,021,135 ) (9,280,727 ) (13,764,906 ) Total assets 220,052,465 34,078,909 42,800,955 296,932,329 Depreciation and amortization expense 1,159,732 564,396 155 1,724,283 Three Months Ended June 30, 2021 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 16,347,880 $ 1,447,001 $ 35,709 $ 17,830,590 Cost of product revenue 17,382,292 1,450,332 - 18,832,624 Loss from operations (8,337,405 ) (2,794,219 ) (4,449,608 ) (15,581,232 ) Interest and other expense, net (78,793 ) (366 ) (3,244,912 ) (3,324,071 ) Net loss (8,416,198 ) (2,794,585 ) (7,694,520 ) (18,905,303 ) Total assets 169,799,509 20,593,411 42,420,872 232,813,792 Depreciation and amortization expense 1,055,537 268,927 1,530 1,325,994 Six Months Ended June 30, 2022 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 57,848,744 $ 5,087,939 $ 71,417 $ 63,008,100 Cost of product revenue 46,500,902 5,075,758 - 51,576,660 Loss from operations (4,720,538 ) (7,883,894 ) (11,385,373 ) (23,989,805 ) Interest and other expense, net (67,062 ) (1,066 ) (8,044,889 ) (8,113,017 ) Loss on extinguishment of debt - - (6,669,941 ) (6,669,941 ) Net loss (4,787,600 ) (7,884,960 ) (26,100,203 ) (38,772,763 ) Capital expenditures 2,584,906 4,197,263 - 6,782,169 Depreciation and amortization expense 2,271,683 1,041,899 918 3,314,500 Six Months Ended June 30, 2021 ADMA BioManufacturing Plasma Collection Centers Corporate Consolidated Revenues $ 29,768,923 $ 4,038,868 $ 71,417 $ 33,879,208 Cost of product revenue 32,832,049 3,770,697 - 36,602,746 Loss from operations (17,843,093 ) (4,765,060 ) (8,137,328 ) (30,745,481 ) Interest and other expense, net (100,307 ) (750 ) (6,438,706 ) (6,539,763 ) Net loss (17,943,400 ) (4,765,810 ) (14,576,034 ) (37,285,244 ) Capital expenditures 2,725,432 4,321,303 - 7,046,735 Depreciation and amortization expense 2,065,307 486,918 3,397 2,555,622
Net Revenues According to Geographic Area	Net revenues according to geographic area, based on the location of where the product is shipped, is as follows: Three Months Ended June 30, Six Months Ended June 30, 2022 2021 2022 2021 United States $ 31,274,844 $ 15,424,839 $ 58,590,995 $ 29,102,848 International 2,630,163 2,405,751 4,417,105 4,776,360 Total revenues $ 33,905,007 $ 17,830,590 $ 63,008,100 $ 33,879,208

LEASE OBLIGATIONS (Tables)

LEASE OBLIGATIONS (Tables)	6 Months Ended
	Jun. 30, 2022
LEASE OBLIGATIONS [Abstract]
Payments Under Lease Obligations	Scheduled payments under the Company’s lease obligations are as follows: Remainder of 2022 $ 945,228 Year ended December 31, 2023 2,247,057 2024 2,223,314 2025 2,246,432 2026 1,996,036 2027 2,040,690 Thereafter 8,238,571 Total payments 19,937,328 Less: imputed interest (8,486,760 ) Current portion (579,661 ) Balance at June 30, 2022 $ 10,870,907

SUPPLEMENTAL DISCLOSURE OF CA_2

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION (Tables)	6 Months Ended
	Jun. 30, 2022
SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION [Abstract]
Supplemental Cash Flow Information	Supplemental cash flow information for the six months ended June 30, 2022 and 2021 is as follows: 2022 2021 SUPPLEMENTAL CASH FLOW INFORMATION: Cash paid for interest $ 5,989,332 $ 5,534,279 Noncash Financing and Investing Activities: Equipment acquired reflected in accounts payable and accrued liabilities $ 1,164,319 $ 1,005,546 Right-to-use assets in exchange for lease obligations $ 3,660,890 $ 2,844,875 Warrants issued in connection with notes payable $ 9,569,604 $ -

ORGANIZATION AND BUSINESS (Deta

ORGANIZATION AND BUSINESS (Details) $ in Millions	6 Months Ended
	Jun. 30, 2022 USD ($) Facility Product
Organization and Business [Abstract]
Number of plasma collection facilities under approval and development	10
Number of FDA-licensed plasma collection facilities	6
Number of additional plasma collections centers in operation and collection of plasma	2
Number of remaining plasma collection facilities under construction	2
Number of FDA approved product | Product	3
Working capital | $	$ 194.7
Cash and cash equivalents | $	$ 52.4

SUMMARY OF SIGNIFICANT ACCOUN_4

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Accounts Receivable (Details) $ in Millions	6 Months Ended	12 Months Ended
	Jun. 30, 2022 USD ($) Customer	Dec. 31, 2021 USD ($) Customer
Accounts Receivable [Abstract]
Accounts receivable, allowances for contractual credits and doubtful accounts | $	$ 0.1	$ 0.2
Accounts Receivable [Member] | Customer Concentration Risk [Member] | Three Customers [Member]
Accounts Receivable [Abstract]
Number of customers | Customer	3	3
Percentage of account receivables	84%	94%

SUMMARY OF SIGNIFICANT ACCOUN_5

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Goodwill (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Goodwill [Abstract]
Goodwill	$ 3,529,509		$ 3,529,509
Impairment charges related to goodwill	$ 0	$ 0

SUMMARY OF SIGNIFICANT ACCOUN_6

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Impairment of Long-lived Assets (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Impairment of Long-lived Assets [Abstract]
Impairment of long-lived assets	$ 0	$ 0

SUMMARY OF SIGNIFICANT ACCOUN_7

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Revenue Recognition (Details) - Customer	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Two Customers [Member] | Revenues [Member] | Customer Concentration Risk [Member]
Revenue Recognition [Abstract]
Number of customers	2
Percentage of consolidated revenues	73%
Five Customers [Member] | Revenues [Member] | Customer Concentration Risk [Member]
Revenue Recognition [Abstract]
Number of customers		5
Percentage of consolidated revenues		85%
Biotest License Agreement [Member]
Revenue Recognition [Abstract]
Amortization period	22 years

SUMMARY OF SIGNIFICANT ACCOUN_8

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Loss per Common Share (Details) - shares	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Loss Per Common Share [Abstract]
Potentially dilutive securities (in shares)	26,803,460	12,997,322
Stock Options [Member]
Loss Per Common Share [Abstract]
Potentially dilutive securities (in shares)	8,504,179	7,783,029
Restricted Stock Units [Member]
Loss Per Common Share [Abstract]
Potentially dilutive securities (in shares)	4,742,383	686,133
Warrants [Member]
Loss Per Common Share [Abstract]
Potentially dilutive securities (in shares)	13,556,898	4,528,160

SUMMARY OF SIGNIFICANT ACCOUN_9

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Stock-based Compensation (Details)	6 Months Ended
	Jun. 30, 2022
Stock-based Compensation [Abstract]
Equity incentive plans, vesting period	4 years
Equity incentive plans, term	10 years

SUMMARY OF SIGNIFICANT ACCOU_10

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES, Income Taxes (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Income Taxes [Abstract]
Unrecognized tax benefits	$ 0	$ 0

INVENTORIES (Details)

INVENTORIES (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
INVENTORIES [Abstract]
Raw materials	$ 38,321,843	$ 36,755,720
Work-in-process	51,136,409	58,968,535
Finished goods	56,617,207	28,999,836
Total inventories	$ 146,075,459	$ 124,724,091

INTANGIBLE ASSETS, Summary (Det

INTANGIBLE ASSETS, Summary (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Finite-Lived Intangible Assets, Net [Abstract]
Cost	$ 5,007,467		$ 5,007,467		$ 5,007,467
Accumulated amortization	3,636,375		3,636,375		3,278,699
Net	1,371,092		1,371,092		1,728,768
Amortization of intangible assets	178,838	$ 178,838	357,676	$ 357,676
Trademark and Other Intangible Rights Related to Nabi-HB [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Cost	4,100,046		4,100,046		4,100,046
Accumulated amortization	2,977,415		2,977,415		2,684,554
Net	1,122,631		1,122,631		1,415,492
Rights to Intermediates [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Cost	907,421		907,421		907,421
Accumulated amortization	658,960		658,960		594,145
Net	$ 248,461		$ 248,461		$ 313,276

INTANGIBLE ASSETS, Future Aggre

INTANGIBLE ASSETS, Future Aggregate Amortization Expense (Details)	Jun. 30, 2022 USD ($)
Estimated Aggregate Amortization Expense [Abstract]
Remainder of 2022	$ 357,676
2023	715,352
2024	$ 298,064

PROPERTY AND EQUIPMENT (Details

PROPERTY AND EQUIPMENT (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	$ 71,176,031		$ 71,176,031		$ 64,206,927
Less: accumulated depreciation	(16,224,764)		(16,224,764)		(13,271,853)
Total property, plant and equipment, net	54,951,267		54,951,267		50,935,074
Depreciation expense	1,500,000	$ 1,100,000	$ 3,000,000	$ 2,200,000
Minimum [Member]
Property, Plant and Equipment [Abstract]
Estimated useful life			3 years
Maximum [Member]
Property, Plant and Equipment [Abstract]
Estimated useful life			10 years
Manufacturing and Laboratory Equipment [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	17,919,714		$ 17,919,714		16,702,991
Office Equipment and Computer Software [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	5,133,876		5,133,876		4,082,462
Furniture and Fixtures [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	4,364,091		4,364,091		3,389,140
Construction in Process [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	4,830,287		4,830,287		5,496,222
Leasehold Improvements [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	15,492,458		15,492,458		11,129,639
Land [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	4,339,441		4,339,441		4,339,441
Buildings and Building Improvements [Member]
Property, Plant and Equipment [Abstract]
Property, plant and equipment, gross	$ 19,096,164		$ 19,096,164		$ 19,067,032
Building [Member]
Property, Plant and Equipment [Abstract]
Estimated useful life			30 years

ACCRUED EXPENSES AND OTHER CU_3

ACCRUED EXPENSES AND OTHER CURRENT LIABILITIES (Details) - USD ($)	Jun. 30, 2022	Dec. 31, 2021
Accrued Expenses and Other Current Liabilities [Abstract]
Accrued rebates	$ 7,764,200	$ 5,040,200
Accrued distribution fees	1,850,105	4,739,651
Accrued incentives	1,951,768	4,066,109
Accrued testing	344,892	1,189,970
Accrued payroll	1,019,912	1,167,072
Other	3,030,193	1,011,986
Total accrued expenses and other current liabilities	$ 15,961,070	$ 17,214,988

DEBT (Details)

DEBT (Details)		3 Months Ended			6 Months Ended
	Mar. 23, 2022 USD ($) d $ / shares shares	Dec. 31, 2026 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Senior Notes Payable [Abstract]
Notes payable			$ 152,795,660		$ 152,795,660		$ 100,000,000
Less: Debt discount			(12,984,729)		(12,984,729)		(5,133,761)
Senior notes payable			139,810,931		139,810,931		$ 94,866,239
Payment for outstanding obligations					100,000,000	$ 0
Loss on extinguishment of debt			0	$ 0	(6,669,941)	0
Interest paid-in-kind					1,045,660	0
Revenues			$ 33,905,007	$ 17,830,590	$ 63,008,100	$ 33,879,208
Hayfin Credit Agreement [Member]
Senior Notes Payable [Abstract]
Less: Debt discount	$ (13,400,000)
Maturity date					Mar. 23, 2029
Upfront fee paid in kind	1,800,000
Loss on extinguishment of debt	$ (6,700,000)
Applicable margin	9.50%
Effective interest rate			13%		13%
Percentage of interest amount to pay in kind	2.50%
Interest paid-in-kind					$ 1,000,000
Percentage of exit fee of outstanding principal amount being paid					1%
Scheduled principal payments	$ 0
Increase applicable margin	3%
Number of business days prior written notice for prepay outstanding principal | d	5
Shares issued upon exercise of warrants (in shares) | shares	9,103,047
Warrant exercise price per share (in dollars per share) | $ / shares	$ 1.6478
Trailing period for VWAP					30 days
Fair value of warrants	$ 9,600,000
Hayfin Credit Agreement [Member] | Minimum [Member]
Senior Notes Payable [Abstract]
Cash balance	$ 6,000,000
Revenues			$ 75,000,000
Hayfin Credit Agreement [Member] | Maximum [Member] | Forecast [Member]
Senior Notes Payable [Abstract]
Revenues		$ 250,000,000
Hayfin Credit Agreement [Member] | Prepaid on or Prior to First Anniversary [Member]
Senior Notes Payable [Abstract]
Percentage of prepaid principal amount	7%
Hayfin Credit Agreement [Member] | Prepaid after the First Anniversary [Member]
Senior Notes Payable [Abstract]
Percentage of prepaid principal amount	3%
Hayfin Credit Agreement [Member] | Prepaid after the Second Anniversary [Member]
Senior Notes Payable [Abstract]
Percentage of prepaid principal amount	1%
Hayfin Credit Agreement [Member] | Federal Funds Rate [Member]
Senior Notes Payable [Abstract]
Credit agreement, interest rate provided	0.50%
Hayfin Credit Agreement [Member] | Secured Overnight Financing Rate [Member]
Senior Notes Payable [Abstract]
Credit agreement, interest rate provided	1%
Term of variable rate					1 month
Applicable margin	8.50%
Hayfin Credit Agreement [Member] | Secured Overnight Financing Rate [Member] | Minimum [Member]
Senior Notes Payable [Abstract]
Term of variable rate					1 month
Hayfin Credit Agreement [Member] | Secured Overnight Financing Rate [Member] | Maximum [Member]
Senior Notes Payable [Abstract]
Term of variable rate					3 months
Hayfin Credit Agreement [Member] | Base Rate [Member]
Senior Notes Payable [Abstract]
Percentage of floor interest rate	1.25%
Hayfin Credit Facility [Member] | Hayfin Credit Agreement [Member]
Senior Notes Payable [Abstract]
Maturity date					Mar. 23, 2027
Hayfin Credit Facility [Member] | Hayfin Credit Agreement [Member] | Maximum [Member]
Senior Notes Payable [Abstract]
Notes payable	$ 175,000,000
Hayfin Closing Date Loan [Member]
Senior Notes Payable [Abstract]
Payment for outstanding obligations	100,000,000
Hayfin Closing Date Loan [Member] | Hayfin Credit Agreement [Member]
Senior Notes Payable [Abstract]
Notes payable	150,000,000
Redemption premium	2,000,000
Payment for certain fees and expenses	600,000
Effective interest rate			10.75%		10.75%
Hayfin Delayed Draw Loan [Member] | Hayfin Credit Agreement [Member]
Senior Notes Payable [Abstract]
Notes payable	$ 25,000,000
Maturity date					Mar. 22, 2023

STOCKHOLDERS' EQUITY, Preferred

STOCKHOLDERS' EQUITY, Preferred Stock (Details) - $ / shares	Jun. 30, 2022	Dec. 31, 2021
Preferred Stock [Abstract]
Preferred stock, shares authorized (in shares)	10,000,000	10,000,000
Preferred stock, par value (in dollars per share)	$ 0.0001	$ 0.0001
Preferred stock, outstanding (in shares)	0	0

STOCKHOLDERS' EQUITY, Common St

STOCKHOLDERS' EQUITY, Common Stock (Details) - USD ($)				3 Months Ended		6 Months Ended
	Sep. 03, 2021	Feb. 03, 2021	Aug. 05, 2020	Jun. 30, 2021	Mar. 31, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Common Stock [Abstract]
Common stock, shares authorized (in shares)						300,000,000		300,000,000
Common stock, par value (in dollars per share)						$ 0.0001		$ 0.0001
Common stock, shares outstanding (in shares)						196,356,232		195,813,817
Warrants outstanding (in shares)						50,523,424
Common stock, available for issuance (in shares)						53,120,344
Common stock issuable under agreement				$ 17,189,560	$ 41,912,515
Net proceeds from issuance of common stock						$ 0	$ 59,102,075
Sale Agreement [Member] | Jefferies LLC [Member] | Maximum [Member]
Common Stock [Abstract]
Common stock issuable under agreement			$ 50,000,000
Sale Agreement, Amended [Member] | Jefferies LLC [Member] | Maximum [Member]
Common Stock [Abstract]
Common stock issuable under agreement		$ 105,400,000
Distribution Agreement [Member] | Raymond James & Associates Inc. [Member]
Common Stock [Abstract]
Common stock issuable under agreement						$ 42,800,000
Common stock shares sold during the period (in shares)						0
Distribution Agreement [Member] | Raymond James & Associates Inc. [Member] | Maximum [Member]
Common Stock [Abstract]
Common stock issuable under agreement	$ 50,000,000
Common Stock [Member]
Common Stock [Abstract]
Warrants outstanding (in shares)						13,556,898		4,528,160
Common stock issuable under agreement				$ 883	$ 1,808
Common stock shares sold during the period (in shares)				8,827,045	18,080,708
Common Stock [Member] | Sale Agreement [Member] | Jefferies LLC [Member]
Common Stock [Abstract]
Common stock shares sold during the period (in shares)							26,907,753
Net proceeds from issuance of common stock							$ 59,100,000

STOCKHOLDERS' EQUITY, Warrants

STOCKHOLDERS' EQUITY, Warrants (Details) - USD ($) $ / shares in Units, $ in Millions		6 Months Ended
	Mar. 23, 2022	Jun. 30, 2022	Dec. 31, 2021
Warrants [Abstract]
Warrants outstanding (in shares)		50,523,424
Hayfin Credit Agreement [Member]
Warrants [Abstract]
Warrant to purchase shares of common stock (in shares)	9,103,047
Fair value of warrants	$ 9.6
Expected term		7 years
Volatility	68.10%
Dividend yield	0%
Risk-free interest rate	2.36%
Weighted average exercise price of warrants (in dollars per share)	$ 1.6478
Common Stock [Member]
Warrants [Abstract]
Warrants expired (in shares)		74,309
Warrants outstanding (in shares)		13,556,898	4,528,160
Weighted average exercise price of warrants (in dollars per share)		$ 2	$ 2.82

STOCKHOLDERS' EQUITY, Equity In

STOCKHOLDERS' EQUITY, Equity Incentive Plans (Details) - USD ($)		3 Months Ended		6 Months Ended
	Mar. 23, 2022	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Jun. 21, 2022
Stock Options [Abstract]
Common stock, available for issuance (in shares)		53,120,344		53,120,344
Restricted Stock Units [Abstract]
Restricted stock units vested over a period				4 years
Total stock-based compensation expense, Amount [Abstract]
Total stock-based compensation expense		$ 1,191,047	$ 805,189	$ 2,832,435	$ 1,586,586
Hayfin Credit Agreement [Member]
Fair Value Assumptions and Methodology [Abstract]
Expected term				7 years
Volatility	68.10%
Dividend yield	0%
Risk-free interest rate	2.36%
Research and Development [Member]
Total stock-based compensation expense, Amount [Abstract]
Total stock-based compensation expense		4,898	42,479	$ 9,569	147,706
Plasma Center Operating Expenses [Member]
Total stock-based compensation expense, Amount [Abstract]
Total stock-based compensation expense		19,615	13,637	40,667	24,455
Selling, General and Administrative [Member]
Total stock-based compensation expense, Amount [Abstract]
Total stock-based compensation expense		1,068,215	665,836	2,585,817	1,254,327
Cost of Product Revenue [Member]
Total stock-based compensation expense, Amount [Abstract]
Total stock-based compensation expense		$ 98,319	$ 83,237	$ 196,382	$ 160,098
2022 Compensation Plan [Member]
Stock Options [Abstract]
Common stock, available for issuance (in shares)						18,000,000
Stock Options [Member]
Fair Value Assumptions and Methodology [Abstract]
Volatility				68%	69%
Dividend yield				0%	0%
Stock Options [Abstract]
Number of stock options granted (in shares)				1,194,032	1,658,050
Weighted average remaining contractual life of stock options, outstanding				6 years 6 months
Weighted average remaining contractual life of stock options, expected to vest				6 years 6 months
Weighted average remaining contractual life of stock options, exercisable				5 years 4 months 24 days
Stock Option, Shares [Abstract]
Options outstanding, vested and expected to vest, beginning balance (in shares)				7,862,722
Forfeited (in shares)				(19,371)
Expired (in shares)				(533,204)
Granted (in shares)				1,194,032
Options outstanding, vested and expected to vest, ending balance (in shares)		8,504,179		8,504,179
Options exercisable (in shares)		5,825,013		5,825,013
Stock Options, Weighted Average Exercise Price [Abstract]
Options outstanding, vested and expected to vest, weighted average exercise price, beginning balance (in dollars per share)				$ 3.93
Forfeited, weighted average exercise price (in dollars per share)				2.24
Expired, weighted average exercise price (in dollars per share)				6.78
Granted, weighted average exercise price (in dollars per share)				1.67
Options outstanding, vested and expected to vest, weighted average exercise price, ending balance (in dollars per share)		$ 3.43		3.43
Options exercisable, weighted average exercise price (in dollars per share)		$ 4.04		$ 4.04
Stock Options [Member] | Minimum [Member]
Fair Value Assumptions and Methodology [Abstract]
Expected term				5 years 6 months	5 years 6 months
Risk-free interest rate				1.72%	0.80%
Stock Options [Member] | Maximum [Member]
Fair Value Assumptions and Methodology [Abstract]
Expected term				6 years 3 months 18 days	6 years 3 months 18 days
Risk-free interest rate				1.73%	1.14%
Stock Options [Member] | Equity Incentive Plans [Member]
Stock Options, Weighted Average Exercise Price [Abstract]
Unrecognized compensation expense, stock options		$ 3,300,000		$ 3,300,000
Unrecognized compensation expense recognition period				2 years 4 months 24 days
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units [Abstract]
Number of restricted stock units granted (in shares)				1,109,266	542,244
Shares withheld for tax withholding obligation (in shares)		269,601		269,601
Amount of shares withheld for tax withholding obligation		$ 400,000		$ 400,000
Unvested RSU, Shares [Abstract]
Beginning balance (in shares)				4,485,133
Granted (in shares)				1,109,266
Vested (in shares)				(812,016)
Forfeited (in shares)				(40,000)
Ending balance (in shares)		4,742,383		4,742,383
Unvested RSU, Weighted Average Grant Date Fair Value
Unvested, Weighted average grant date fair value, beginning balance (in dollars per share)				$ 1.34
Granted, Weighted average grant date fair value (in dollars per share)				1.68
Vested, Weighted average grant date fair value (in dollars per share)				1.41
Forfeited, Weighted average grant date fair value (in dollars per share)				1.22
Unvested, Weighted average grant date fair value, ending balance (in dollars per share)		$ 1.41		$ 1.41
Restricted Stock Units (RSUs) [Member] | Directors [Member]
Restricted Stock Units [Abstract]
Restricted stock units vested over a period				1 year
Restricted Stock Units (RSUs) [Member] | Employees [Member]
Restricted Stock Units [Abstract]
Restricted stock units vested over a period				4 years
Restricted Stock Units (RSUs) [Member] | Equity Incentive Plans [Member]
Stock Options, Weighted Average Exercise Price [Abstract]
Unrecognized compensation expense recognition period				2 years 8 months 12 days
Unvested RSU, Weighted Average Grant Date Fair Value
Unrecognized compensation expense, non option		$ 5,100,000		$ 5,100,000
Milestone Based Restricted Stock (RSUs) [Member] | BIVIGAM [Member]
Unvested RSU, Shares [Abstract]
Vested (in shares)				(382,117)
Milestone Based Restricted Stock (RSUs) [Member] | Hayfin Credit Agreement [Member]
Unvested RSU, Shares [Abstract]
Vested (in shares)				(254,745)

RELATED PARTY TRANSACTIONS (Det

RELATED PARTY TRANSACTIONS (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Perceptive [Member]
Related Party Transactions [Abstract]
Minimum percentage of common stock held by lender	5%
Areth, LLC [Member]
Related Party Transactions [Abstract]
Rent expense	$ 60,000	$ 60,000
Genesis [Member]
Related Party Transactions [Abstract]
Purchased materials amount	$ 100,000	$ 100,000

COMMITMENTS AND CONTINGENCIES (

COMMITMENTS AND CONTINGENCIES (Details)			3 Months Ended		6 Months Ended		12 Months Ended
	Apr. 01, 2019 USD ($)	Dec. 19, 2012 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($) Term Facility Tranche Center	Jun. 30, 2021 USD ($)	Dec. 31, 2021 Facility	Jun. 15, 2022 USD ($)	Sep. 30, 2021 USD ($)
Vendor Commitments [Abstract]
Number of FDA Inspections | Facility							2
Number of plasma collection facilities | Facility					10
Plasma supply agreement term					10 years
Plasma purchased from Grifols					$ 22,800,000	$ 17,500,000
Percentage of inventory purchases					66%	67%
Post-Marketing Commitments [Abstract]
Research and Development Expense	$ 2,000,000		$ 873,386	$ 1,158,866	$ 1,497,497	$ 2,146,515
Revenue Benchmark [Member] | Customer Concentration Risk [Member] | International Customers [Member]
Vendor Commitments [Abstract]
Concentration risk, percentage					7%	14%
Minimum [Member]
Post-Marketing Commitments [Abstract]
Research and Development Expense		$ 3,000,000
Maximum [Member]
Post-Marketing Commitments [Abstract]
Research and Development Expense		$ 4,000,000
Employee Retention Program [Member]
Other Commitments [Abstract]
Number of tranches | Tranche					2
Retention amount paid to employees, tranche one									$ 1,300,000
Retention amount payable to employees, second tranche								$ 1,300,000
Amount of each tranche recognized over the retention service period			$ 800,000		$ 800,000
2011 Plasma Purchase Agreement [Member]
Vendor Commitments [Abstract]
Plasma purchase agreement term					10 years
Number of renewal terms | Term					2
Plasma purchase agreement renewal period					5 years
Number of plasma collection centers that collects RSV Plasma which were transferred to BPC | Center					2
Percentage of plasma purchase price equal to cost					5%
2011 Plasma Purchase Agreement [Member] | Maximum [Member]
Vendor Commitments [Abstract]
Number of plasma collection facilities | Facility					5
2017 Plasma Purchase Agreement [Member]
Vendor Commitments [Abstract]
Number of plasma collection facilities | Facility					10
Plasma purchase agreement term					5 years
Number of renewal terms | Term					2
Plasma purchase agreement renewal period					2 years

SEGMENTS (Details)

SEGMENTS (Details)	3 Months Ended				6 Months Ended
	Jun. 30, 2022 USD ($)	Mar. 31, 2022 USD ($)	Jun. 30, 2021 USD ($)	Mar. 31, 2021 USD ($)	Jun. 30, 2022 USD ($) Facility	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Segment Reporting Information [Abstract]
Number of plasma collection facilities | Facility					10
Number of FDA-licensed plasma collection facilities | Facility					6
Number of additional plasma collections centers in operation and collection of plasma | Facility					2
Number of remaining plasma collection facilities under construction | Facility					2
Revenues	$ 33,905,007		$ 17,830,590		$ 63,008,100	$ 33,879,208
Cost of product revenue	26,135,614		18,832,624		51,576,660	36,602,746
Loss from operations	(9,174,739)		(15,581,232)		(23,989,805)	(30,745,481)
Interest and other expense, net	(4,590,167)		(3,324,071)		(8,113,017)	(6,539,763)
Loss on extinguishment of debt	0		0		(6,669,941)	0
Net loss	(13,764,906)	$ (25,007,857)	(18,905,303)	$ (18,379,941)	(38,772,763)	(37,285,244)
Capital expenditures					6,782,169	7,046,735
Total assets	296,932,329		232,813,792		296,932,329	232,813,792	$ 276,252,724
Depreciation and amortization expense	1,724,283		1,325,994		3,314,500	2,555,622
United States [Member]
Segment Reporting Information [Abstract]
Revenues	31,274,844		15,424,839		58,590,995	29,102,848
International [Member]
Segment Reporting Information [Abstract]
Revenues	2,630,163		2,405,751		4,417,105	4,776,360
Corporate [Member]
Segment Reporting Information [Abstract]
Revenues	35,709		35,709		71,417	71,417
Cost of product revenue	0		0		0	0
Loss from operations	(4,708,692)		(4,449,608)		(11,385,373)	(8,137,328)
Interest and other expense, net	(4,572,035)		(3,244,912)		(8,044,889)	(6,438,706)
Loss on extinguishment of debt					(6,669,941)
Net loss	(9,280,727)		(7,694,520)		(26,100,203)	(14,576,034)
Capital expenditures					0	0
Total assets	42,800,955		42,420,872		42,800,955	42,420,872
Depreciation and amortization expense	155		1,530		918	3,397
Operating Segments [Member] | ADMA BioManufacturing [Member]
Segment Reporting Information [Abstract]
Revenues	32,120,119		16,347,880		57,848,744	29,768,923
Cost of product revenue	24,287,122		17,382,292		46,500,902	32,832,049
Loss from operations	(445,248)		(8,337,405)		(4,720,538)	(17,843,093)
Interest and other expense, net	(17,796)		(78,793)		(67,062)	(100,307)
Loss on extinguishment of debt					0
Net loss	(463,044)		(8,416,198)		(4,787,600)	(17,943,400)
Capital expenditures					2,584,906	2,725,432
Total assets	220,052,465		169,799,509		220,052,465	169,799,509
Depreciation and amortization expense	1,159,732		1,055,537		2,271,683	2,065,307
Operating Segments [Member] | Plasma Collection Centers [Member]
Segment Reporting Information [Abstract]
Revenues	1,749,179		1,447,001		5,087,939	4,038,868
Cost of product revenue	1,848,492		1,450,332		5,075,758	3,770,697
Loss from operations	(4,020,799)		(2,794,219)		(7,883,894)	(4,765,060)
Interest and other expense, net	(336)		(366)		(1,066)	(750)
Loss on extinguishment of debt					0
Net loss	(4,021,135)		(2,794,585)		(7,884,960)	(4,765,810)
Capital expenditures					4,197,263	4,321,303
Total assets	34,078,909		20,593,411		34,078,909	20,593,411
Depreciation and amortization expense	$ 564,396		$ 268,927		$ 1,041,899	$ 486,918

LEASE OBLIGATIONS (Details)

LEASE OBLIGATIONS (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
LEASE OBLIGATIONS [Abstract]
Incremental borrowing rate			13%
Aggregate lease expense	$ 500,000	$ 400,000	$ 900,000	$ 600,000
Cash payments for lease	400,000	$ 600,000	800,000	$ 800,000
Operating and financing lease liabilities	$ 11,500,000		$ 11,500,000		$ 8,100,000
Weighted average remaining term	9 years 1 month 6 days		9 years 1 month 6 days
Payments Under Lease Obligations [Abstract]
Remainder of 2022	$ 945,228		$ 945,228
Year ended December 31, 2023	2,247,057		2,247,057
2024	2,223,314		2,223,314
2025	2,246,432		2,246,432
2026	1,996,036		1,996,036
2027	2,040,690		2,040,690
Thereafter	8,238,571		8,238,571
Total payments	19,937,328		19,937,328
Less: imputed interest	(8,486,760)		(8,486,760)
Current portion	(579,661)		(579,661)		(591,084)
Balance at June 30, 2022	$ 10,870,907		$ 10,870,907		$ 7,462,388

SUPPLEMENTAL DISCLOSURE OF CA_3

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION (Details) - USD ($)	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
SUPPLEMENTAL CASH FLOW INFORMATION [Abstract]
Cash paid for interest	$ 5,989,332	$ 5,534,279
Noncash Financing and Investing Activities [Abstract]
Equipment acquired reflected in accounts payable and accrued liabilities	1,164,319	1,005,546
Right-to-use assets in exchange for lease obligations	3,660,890	2,844,875
Warrants issued in connection with notes payable	$ 9,569,604	$ 0