ReShape Lifesciences 10-Q 12 Aug 16 2016 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2016	Aug. 11, 2016
Document Information [Line Items]
Document Type	10-Q
Amendment Flag	false
Document Period End Date	Jun. 30, 2016
Document Fiscal Year Focus	2,016
Document Fiscal Period Focus	Q2
Trading Symbol	ETRM
Entity Registrant Name	EnteroMedics Inc
Entity Central Index Key	1,371,217
Current Fiscal Year End Date	--12-31
Entity Filer Category	Smaller Reporting Company
Entity Common Stock, Shares Outstanding		27,294,917

Consolidated Balance Sheets

Consolidated Balance Sheets - USD ($)	Jun. 30, 2016	Dec. 31, 2015
Current assets:
Cash and cash equivalents	$ 11,517,041	$ 7,927,240
Accounts receivable	182,527	57,928
Inventory	1,957,821	1,686,324
Prepaid expenses and other current assets	462,080	831,495
Total current assets	14,119,469	10,502,987
Property and equipment, net	259,150	326,296
Other assets	609,069	757,802
Total assets	14,987,688	11,587,085
Current liabilities:
Current portion of convertible notes payable	6,504,543	717,391
Accounts payable	356,978	172,050
Accrued expenses	3,441,887	3,595,415
Accrued interest payable		1,172
Total current liabilities	10,303,408	4,486,028
Convertible notes payable, less current portion (net of discounts of $102,450 and $149,340 at June 30, 2016 and December 31, 2015, respectively)	7,830,458	549,791
Common stock warrant liability	463,422	2,877,817
Total liabilities	18,597,288	7,913,636
Commitments and contingencies (note 5)
Stockholders' equity:
Common stock, $0.01 par value; 150,000,000 and 13,333,333 shares authorized at June 30, 2016 and December 31, 2015, respectively; 13,223,069 and 7,163,820 shares issued and outstanding at June 30, 2016 and December 31, 2015, respectively	132,231	71,638
Additional paid-in capital	286,242,634	281,182,349
Accumulated deficit	(289,984,465)	(277,580,538)
Total stockholders' (deficit) equity	(3,609,600)	3,673,449
Total liabilities and stockholders' equity	$ 14,987,688	$ 11,587,085

Consolidated Balance Sheets (Pa

Consolidated Balance Sheets (Parenthetical) - USD ($)	Jun. 30, 2016	Dec. 31, 2015
Convertible notes payable, less current portion, discounts	$ 102,450	$ 149,340
Common stock, par value	$ 0.01	$ 0.01
Common stock, shares authorized	150,000,000	13,333,333
Common stock, shares issued	13,223,069	7,163,820
Common stock, shares outstanding	13,223,069	7,163,820

Consolidated Statements of Oper

Consolidated Statements of Operations - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Sales	$ 276,000	$ 79,000	$ 348,000	$ 79,000
Cost of goods sold	155,304	30,763	195,439	30,763
Gross profit	120,696	48,237	152,561	48,237
Operating expenses:
Selling, general and administrative	5,585,548	4,936,363	11,726,725	9,663,882
Research and development	1,193,607	2,452,787	2,625,988	4,689,393
Total operating expenses	6,779,155	7,389,150	14,352,713	14,353,275
Operating loss	(6,658,459)	(7,340,913)	(14,200,152)	(14,305,038)
Other income (expense):
Interest income	1,807	422	3,498	1,289
Interest expense	(852,946)	(60,423)	(2,002,240)	(274,969)
Change in value of warrant liability	1,309,099		3,088,513
Change in value of convertible notes payable	1,208,594		709,026
Other, net	(3,260)	(2,848)	(2,572)	933
Net loss	$ (4,995,165)	$ (7,403,762)	$ (12,403,927)	$ (14,577,785)
Net loss per share-basic and diluted	$ (0.49)	$ (1.49)	$ (1.37)	$ (2.97)
Shares used to compute basic and diluted net loss per share	10,297,589	4,960,292	9,078,837	4,904,984

Consolidated Statements of Comp

Consolidated Statements of Comprehensive Loss - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Net loss	$ (4,995,165)	$ (7,403,762)	$ (12,403,927)	$ (14,577,785)
Comprehensive loss	$ (4,995,165)	$ (7,403,762)	$ (12,403,927)	$ (14,577,785)

Consolidated Statements of Cash

Consolidated Statements of Cash Flows - USD ($)	6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015
Cash flows from operating activities:
Net loss	$ (12,403,927)	$ (14,577,785)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	78,690	97,357
Stock-based compensation	1,846,612	2,920,785
Amortization of commitment fees, debt issuance costs and original issue discount	995,057	196,691
Change in value of convertible notes payable	(709,026)
Change in value of warrant liability	(3,088,513)
Change in operating assets and liabilities:
Accounts receivable	(124,599)	(109,695)
Inventory	(271,497)	(303,919)
Prepaid expenses and other current assets	369,871	83,236
Other assets	(90,754)	(229,319)
Accounts payable	184,928	52,493
Accrued expenses	(51,528)	671,362
Accrued interest payable	775,586	(9,353)
Net cash used in operating activities	(12,489,100)	(11,208,147)
Cash flows from investing activities:
Purchases of property and equipment	(11,544)	(36,454)
Net cash used in investing activities	(11,544)	(36,454)
Cash flows from financing activities:
Proceeds from sale of common stock and warrants for purchase of common stock		6,651,931
Common stock financing costs	(28,000)	(227,557)
Proceeds from convertible notes payable	17,250,000
Repayments on convertible notes payable	(404,762)
Repayments on notes payable		(2,000,000)
Debt issuance costs	(726,793)
Net cash provided by financing activities	16,090,445	4,424,374
Net increase (decrease) in cash and cash equivalents	3,589,801	(6,820,227)
Cash and cash equivalents:
Beginning of period	7,927,240	11,619,167
End of period	11,517,041	4,798,940
Supplemental disclosure:
Cash paid for interest	163,152	$ 87,630
Noncash investing and financing activities:
Conversion of convertible notes and interest payable	$ 3,373,265

Summary of Significant Accounti

Summary of Significant Accounting Policies	6 Months Ended
	Jun. 30, 2016
Summary of Significant Accounting Policies	(1) Summary of Significant Accounting Policies Description of Business EnteroMedics Inc. (the Company) develops and sells implantable systems to treat obesity, metabolic diseases and other gastrointestinal disorders. The Company was incorporated in the state of Minnesota on December 19, 2002 and was reincorporated in Delaware on July 22, 2004. The Company is headquartered in St. Paul, Minnesota. In January 2006, the Company established EnteroMedics Europe Sárl, a wholly-owned subsidiary located in Switzerland. The Company’s board of directors and stockholders approved a 1-for-15 reverse split (the Reverse Stock Split) of the Company’s outstanding common stock that became effective after trading on January 6, 2016. The Reverse Stock Split did not change the par value of the Company’s stock or the number of preferred shares authorized by the Company’s Fifth Amended and Restated Certificate of Incorporation. An amendment to the Certificate of Incorporation was also approved in connection with the Reverse Stock Split to increase the number of shares of the Company’s common stock authorized for issuance to 150 million shares, effective immediately after the Reverse Stock Split on January 6, 2016. All share and per share amounts have been retroactively adjusted to reflect the Reverse Stock Split for all periods presented. Risks and Uncertainties The Company is focused on the design and development of medical devices that use neuroblocking technology to treat obesity, metabolic diseases and other gastrointestinal disorders and currently has approvals to commercially launch the Maestro Rechargeable System in the United States and in Australia, the European Economic Area and other countries that recognize the European CE Mark. The Company has devoted substantially all of its resources to recruiting personnel, developing its product technology, obtaining patents to protect its intellectual property and raising capital, and has recently commenced commercial operations in the United States deriving revenues from its primary business activity in 2015. The Company’s products require approval from the U.S. Food and Drug Administration (FDA) or corresponding foreign regulatory agencies prior to commercial sales. The Company received FDA approval on January 14, 2015 for vBloc Therapy, delivered via the Maestro Rechargeable System, and has begun a controlled commercial launch at select centers in the United States. The Maestro Rechargeable System has also received CE Mark and is listed on the Australian Register of Therapeutic Goods (ARTG). The medical device industry is characterized by frequent and extensive litigation and administrative proceedings over patent and other intellectual property rights. Whether a product infringes a patent involves complex legal and factual issues, the determination of which is often difficult to predict, and the outcome may be uncertain until the court has entered final judgment and all appeals are exhausted. The Company’s competitors may assert that its products or the use of the Company’s products are covered by U.S. or foreign patents held by them. The Company’s activities are subject to significant risks and uncertainties, including the ability to obtain additional financing, and there can be no assurance that the Company will be successful in obtaining additional financing on favorable terms, or at all. If adequate funds are not available, the Company may have to delay development or commercialization of products or license to third parties the rights to commercialize products or technologies that the Company would otherwise seek to commercialize. Basis of Presentation The Company has prepared the accompanying condensed consolidated financial statements in conformity with accounting principles generally accepted in the United States of America. The Company’s fiscal year ends on December 31. The accompanying condensed consolidated financial statements and notes thereto are unaudited. In the opinion of the Company’s management, these statements include all adjustments, which are of a normal recurring nature, necessary to present a fair presentation. Interim results are not necessarily indicative of results for a full year. The condensed consolidated balance sheet as of December 31, 2015 was derived from audited consolidated financial statements, but does not include all disclosures required by accounting principles generally accepted in the United States of America. The information included in this Form 10-Q should be read in conjunction with the Company’s Annual Report on Form 10-K for the year ended December 31, 2015. Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Actual results could differ from those estimates. Principles of Consolidation The accompanying condensed consolidated financial statements include the accounts of the Company and its wholly-owned subsidiary. All intercompany transactions and accounts have been eliminated in consolidation. Fair Value of Financial Instruments Carrying amounts of certain of the Company’s financial instruments, including cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable and accrued liabilities approximate fair value due to their short maturities. The Company’s common stock warrants are required to be reported at fair value and the Company has elected to report its senior amortizing convertible notes at fair value. The fair values of common stock warrants and investments in debt and equity securities, if any, are disclosed in Note 3. The fair value of the Company’s senior amortizing convertible notes is disclosed in Notes 3 and 7. Common Stock Warrant Liability Common stock warrants that were issued in connection with the July 8, 2015 public offering and the November 9, 2015, January 11, 2016 and May 2, 2016 senior amortizing convertible notes are classified as a liability in the condensed consolidated balance sheets, as the common stock warrants issued provide for certain anti-dilution protections in the event shares of common stock or securities convertible into shares of common stock are issued below the then-existing exercise price. The fair value of these common stock warrants is re-measured at each financial reporting period and immediately before exercise, with any changes in fair value being recognized as a component of other income (expense) in the condensed consolidated statements of operations. Cash and Cash Equivalents The Company considers highly liquid investments generally with maturities of 90 days or less when purchased to be cash equivalents. Cash equivalents are stated at cost, which approximates market value. The Company’s cash equivalents are primarily in money market funds and certificates of deposit. The Company deposits its cash and cash equivalents in high-quality credit institutions. Short-Term Investments The Company considers all investments with maturities greater than three months and less than one year at the time of purchase as short-term investments and classifies them as either available for sale or held to maturity. The Company also considers certain investments with maturities greater than one year but which are also held for liquidity purposes and are available for sale as short-term investments. Available-for-sale securities are carried at fair value based on quoted market prices, with the unrealized gains and losses included in other comprehensive income within stockholders’ equity in the condensed consolidated balance sheets. Realized gains and losses and declines in value judged to be other than temporary on available-for-sale securities are included in interest and other income. Interest and dividends on securities classified as available for sale are included in interest income. The cost of securities sold is based on the specific identification method. Short-term investments in debt securities which the Company has the positive intent and ability to hold to maturity are reported at cost, adjusted for premiums and discounts that are recognized in interest income, using the interest method, over the period to maturity. Unrealized losses on held-to-maturity securities reflecting a decline in value determined to be other than temporary are charged to income. Inventory The Company accounts for inventory at the lower of cost or market and records any long-term inventory as other assets in the condensed consolidated balance sheets. Property and Equipment, Net Property and equipment are stated at cost less accumulated depreciation and amortization. Depreciation of property and equipment is computed using the straight-line method over their estimated useful lives of five to seven years for furniture and equipment and three to five years for computer hardware and software. Leasehold improvements are amortized on a straight-line basis over the lesser of their useful life or the term of the lease. Upon retirement or sale, the cost and related accumulated depreciation or amortization are removed from the condensed consolidated balance sheets and the resulting gain or loss is reflected in the condensed consolidated statements of operations. Repairs and maintenance are expensed as incurred. Impairment of Long-Lived Assets The Company evaluates its long-lived assets for impairment by comparison of the carrying amounts to future net undiscounted cash flows expected to be generated by such assets when events or changes in circumstances indicate the carrying amount of an asset may not be recoverable. Should an impairment exist, the impairment loss would be measured based on the excess carrying value of the asset over the asset’s fair value or estimates of future discounted cash flows. The Company has not identified any such impairment losses to date. Income Taxes Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carry-forwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance for deferred income tax assets is recorded when it is more likely than not that some portion or all of the deferred income tax assets will not be realized. The Company has provided a full valuation allowance against the gross deferred tax assets. The Company’s policy is to classify interest and penalties related to income taxes as income tax expense in the condensed consolidated statements of operations. Medical Device Excise Tax On January 14, 2015, the Company received FDA approval for vBloc Therapy, delivered via the Maestro Rechargeable System, and starting in the second quarter of 2015 revenues were generated from sales in the United States. As a result, the Company is now required to pay a quarterly Medical Device Tax which is a part of the Affordable Care Act, which imposes a 2.3% excise tax on the sale of certain medical devices by device manufactures, producers or importers. The excise tax was effective on sales of devices made after December 31, 2012. The Company records the Medical Device Tax as an operating expense in the condensed consolidated statements of operations. A moratorium was placed on the Medical Device Tax for 2016 and 2017. Comprehensive Loss Comprehensive loss is defined as the change in equity of a company during a period from transactions and other events and circumstances excluding transactions resulting from investment owners and distributions to owners. There was no difference from reported net loss for the three and six months ended June 30, 2016 and 2015. Revenue Recognition Revenue is recognized when persuasive evidence of an arrangement exists, title or risk of loss has passed, the selling price is fixed or determinable and collection is reasonably assured. Products are sold through direct sales or medical device distributors and revenue is recognized upon sale to a bariatric center of excellence or a medical device distributor when no right of return or price protection exists. Terms of sales to international distributors are generally EXW, reflecting that goods are shipped “ex works,” in which risk of loss is assumed by the distributor at the shipping point. A provision for returns is recorded only if product sales provide for a right of return. No provision for returns was recorded for the three and six months ended June 30, 2016 and 2015, as the product sales recorded did not provide for rights of return. Research and Development Expenses Research and development expenses are charged to expense as incurred. Research and development expenses include, but are not limited to, product development, clinical trial expenses, including supplies, devices, explants and revisions, quality assurance, regulatory expenses, payroll and other personnel expenses, materials and consulting costs. Net Loss Per Share Basic net loss per share is computed by dividing net loss by the weighted-average number of common shares outstanding during the period. Diluted net loss per share is based on the weighted-average common shares outstanding during the period plus dilutive potential common shares calculated using the treasury stock method. Such potentially dilutive shares are excluded when the effect would be to reduce a net loss per share. The Company’s potential dilutive shares, which include outstanding common stock options and warrants, have not been included in the computation of diluted net loss per share for all periods as the result would be anti-dilutive. The following table sets forth the computation of basic and diluted net loss per share for the three and six months ended June 30, 2016 and 2015: Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Numerator: Net loss $ (4,995,165 ) $ (7,403,762 ) $ (12,403,927 ) $ (14,577,785 ) Denominator for basic and diluted net loss per share: Weighted-average common shares outstanding 10,297,589 4,960,292 9,078,837 4,904,984 Net loss per share—basic and diluted $ (0.49 ) $ (1.49 ) $ (1.37 ) $ (2.97 ) The following table sets forth the potential shares of common stock that are not included in the calculation of diluted net loss per share because to do so would be anti-dilutive as of the end of each period presented: June 30, 2016 2015 Stock options outstanding 1,934,796 15,483,514 Warrants to purchase common stock 4,062,571 24,199,705 Recently Issued or Adopted Accounting Standards In March 2016, the Financial Accounting Standards Board (FASB) issued Compensation-Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting (Accounting Standards Update No. 2016-09 (ASU 2016-09)) In May 2014, FASB issued Revenue from Contracts with Customers, Topic 606 (Accounting Standards Update No. 2014-09 (ASU 2014-09)) There have been no other significant changes in recent accounting pronouncements during the six months ended June 30, 2016 as compared to the recent accounting pronouncements described in the Company’s Annual Report on Form 10-K for the year ended December 31, 2015.

Liquidity and Management's Plan

Liquidity and Management's Plans	6 Months Ended
	Jun. 30, 2016
Liquidity and Management's Plans	(2) Liquidity and Management’s Plans The accompanying condensed consolidated financial statements have been prepared assuming the Company will continue as a going concern. The Company has financed its operations to date principally through the sale of equity securities, debt financing and interest earned on investments. As of June 30, 2016, the Company had $11.5 million of cash and cash equivalents to fund its operations through 2016. On November 4, 2015, the Company entered into a securities purchase agreement (the Purchase Agreement) with institutional investors to issue $25.0 million of senior amortizing convertible notes (the Notes) along with the accompanying warrants. $1.5 million of the Notes was funded at the first closing on November 9, 2015 (the First Closing). An additional $11.0 million of the Notes was funded at the second closing on January 11, 2016 (the Second Closing). Pursuant to two amendments to the Purchase Agreement entered into on May 2, 2016 (the First Amendment), and July 14, 2016 (the Second Amendment), $6.25 million was funded at the third closing on May 2, 2016 (The Third Closing) and the remaining amount, up to $6.25 million, will be funded at the fourth closing, which is scheduled to occur not later than December 1, 2016 (the Fourth Closing), subject to certain terms and conditions (see Note 6). Additionally, the Company has agreed that it will not, for a period of one year after the First Closing, issue any further securities, other than certain excluded securities. The Company’s operations include plans that consider the controlled commercial launch of vBloc Therapy, delivered via the Maestro Rechargeable System, which was approved by the FDA on January 14, 2015. The Company believes that it has the ability to manage the growth of its expenditures and operations depending on the amount of available cash flows. However, the Company will ultimately need to achieve sufficient revenues from product sales and/or obtain additional debt or equity financing to support its operations. In May 2016, the Company received written notices from the Nasdaq Stock Market Nasdaq stating that the Company was not in compliance with the following two Nasdaq listing requirements: (1) the requirement that the Company have a minimum of $2.5 million stockholders’ equity (the Stockholders’ Equity Requirement) and (2) the $1.00 minimum bid price stock price requirement (the Minimum Bid Requirement). On July 19, 2016, the Company received a letter from Nasdaq granting the Company an extension until November 14, 2016 to regain compliance with the Stockholders’ Equity Requirement. The extension was granted based on the plan the Company submitted to Nasdaq to regain compliance with the Stockholders’ Equity Requirement through a combination of note conversions and accelerated principal amortizations and infusions of equity capital prior to the deadline. The Company has 180 calendar days from the May 9, 2016 notice date to regain compliance with the Minimum Bid Requirement. In the event the Company does not regain compliance with this requirement, Nasdaq will provide the Company with written notification that its securities are subject to delisting. At that time, the Company may appeal the delisting determination to a Nasdaq Hearings Panel. Alternatively, if the Company fails to regain compliance with the Minimum Bid Requirement prior to the expiration of the 180 calendar day period, the Company may be granted an additional 180 calendar days to regain compliance with the Minimum Bid Requirement if it (i) meets the continued listing requirement for market value of publicly held shares and all of the other applicable requirements for initial listing on Nasdaq other than the Minimum Bid Requirement, and (ii) provides written notice of its intention to cure the deficiency during the second compliance period by effecting a reverse stock split, if necessary. The Company is actively monitoring its performance with respect to the Stockholders’ Equity Requirement and the Minimum Bid Requirement and will consider all available options to resolve each deficiency and regain compliance with the Nasdaq listing requirements.

Short-term Investments and Fair

Short-term Investments and Fair Value Measurements	6 Months Ended
	Jun. 30, 2016
Short-term Investments and Fair Value Measurements	(3) Short-term Investments and Fair Value Measurements Fair value of financial assets and liabilities is defined as the price that would be received to sell an asset or transfer a liability in an orderly transaction between market participants at the measurement date. A fair value hierarchy has been established that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to unobservable inputs (Level 3 measurements). The three levels of the fair value hierarchy are described below: • Level 1—Unadjusted quoted prices in active markets that are accessible at the measurement date for identical, unrestricted assets or liabilities. • Level 2—Quoted prices for similar assets and liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active or model-derived valuations for which all significant inputs are observable, either directly or indirectly. • Level 3—Prices or valuation techniques that require inputs that are both significant to the fair value measurement and unobservable. The Company’s assets that are measured at fair value on a recurring basis are classified within Level 1 or Level 2 of the fair value hierarchy. The Company does not hold any assets that are measured at fair value using Level 3 inputs. The types of instruments the Company invests in that are valued based on quoted market prices in active markets may include U.S. treasury securities and money market funds. Such instruments are classified by the company within Level 1 of the fair value hierarchy. U.S. treasuries are valued using unadjusted quoted prices for identical assets in active markets that the Company can access. The types of instruments the Company invests in that are valued based on quoted prices in less active markets, broker or dealer quotations, or alternative pricing sources with reasonable levels of price transparency include the Company’s U.S. agency securities, commercial paper, U.S. corporate bonds and municipal obligations. Such instruments are classified by the Company within Level 2 of the fair value hierarchy. The Company values these types of assets using consensus pricing or a weighted average price, which is based on multiple pricing sources received from a variety of industry standard data providers (e.g. Bloomberg), security master files from large financial institutions, and other third-party sources. The multiple prices obtained are then used as inputs into a distribution-curve-based algorithm to determine the daily market price. The Company did not hold any short-term investments classified as available for sale or held to maturity as of June 30, 2016 and December 31, 2015. The fair value of the Company’s common stock warrant liability is calculated using a Black-Scholes valuation model and is classified as Level 2 in the fair value hierarchy. The common stock warrants issued July 8, 2015 had a fair value of $352,206 and $2,759,583 on June 30, 2016 and December 31, 2015, respectively. The common stock warrants issued November 9, 2015 had a fair value of $15,442 and $118,234 on June 30, 2016 and December 31, 2015, respectively. The common stock warrants issued January 11, 2016 had a fair value of $54,125 and $515,157 on June 30, 2016 and January 11, 2016, respectively. The common stock warrants issued May 2, 2016 had a fair value of $32,883 and $150,195 on June 30, 2016 and May 2, 2016, respectively. The fair value was calculated using the following assumptions: July 2015 Warrants November 2015 Warrants June 30, 2016 December 31, 2015 June 30, 2016 December 31, 2015 Risk-free interest rates 0.71 % 1.31 % 1.01 % 1.76 % Expected life 30 months 36 months 52 months 58 months Expected dividends 0 % 0 % 0 % 0 % Expected volatility 93.04 % 97.94 % 94.99 % 86.27 % January 2016 Warrants May 2016 Warrants June 30, 2016 January 11, 2016 June 30, 2016 May 2, 2016 Risk-free interest rates 1.01 % 1.58 % 1.01 % 1.32 % Expected life 54 months 60 months 58 months 60 months Expected dividends 0 % 0 % 0 % 0 % Expected volatility 93.53 % 85.90 % 92.31 % 89.28 % The following table summarizes fair value measurements of the Notes and the common stock warrants issued in 2015 and during the six months ended June 30, 2016 by level at June 30, 2016: Level 1 Level 2 Level 3 Total Senior amortizing convertible notes $ 14,335,000 $ 14,335,000 Common stock warrants $ 463,422 463,422 Total $ 463,422 $ 14,335,000 $ 14,798,422 Through June 30, 2016, the Company had converted $3.2 million of the Notes’ principal and interest into shares of common stock. For the three month and six month periods ended June 30, 2016, respectively, there were gains of $1.2 million and $709,000 recognized in the condensed consolidated statements of operations from changes in fair value of the Notes. On June 30, 2016 and December 31, 2015, the fair value of the outstanding Notes from the First Closing was determined to be $942,000 and $1.3 million, respectively. On June 30, 2016 and January 11, 2016, the fair value of the outstanding Notes from the Second Closing was determined to be $7.9 million and $9.9 million, respectively. On June 30, 2016 and May 2, 2016, the fair value of the outstanding Notes from the Third Closing was determined to be $5.5 million and $6.0 million, respectively. The fair values were calculated using a Binomial Lattice model and the following assumptions: November 2015 Notes January 2016 Notes June 30, 2016 December 31, 2015 June 30, 2016 January 11, 2016 Risk-free interest rates 0.54 % 1.11 % 0.54 % 1.01 % Expected life 1.36 years 1.86 years 1.36 years 1.83 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 68.0 % 57.5 % 68.0 % 60.0 % Fair value per share of common stock $ 0.29 $ 1.95 $ 0.29 $ 1.33 May 2016 Notes June 30, 2016 May 2, 2016 Risk-free interest rates 0.54 % 0.69 % Expected life 1.36 years 1.52 years Expected dividends 0 % 0 % Expected volatility 68.0 % 65.0 % Fair value per share of common stock $ 0.29 $ 0.80

Inventory

Inventory	6 Months Ended
	Jun. 30, 2016
Inventory	(4) Inventory From the Company’s inception, inventory related purchases had been used for research and development related activities and had accordingly been expensed as incurred. In December 2011, the Company began receiving ARTG listings for components of the Maestro Rechargeable System from the Australian Therapeutic Goods Administration, with the final components being listed on the ARTG in January 2012. As a result, the Company determined certain assets were recoverable as inventory beginning in December 2011. The Company accounts for inventory at the lower of cost or market and records any long-term inventory as other assets in the condensed consolidated balance sheets. There was approximately $609,000 and $519,000 of long-term inventory, primarily consisting of raw materials, as of June 30, 2016 and December 31, 2015, respectively. Current inventory consists of the following as of: June 30, 2016 December 31, 2015 Raw materials $ 626,725 $ 576,898 Work-in-process 1,310,121 1,066,345 Finished goods 20,975 43,081 Inventory $ 1,957,821 $ 1,686,324

Commitments and Contingencies

Commitments and Contingencies	6 Months Ended
	Jun. 30, 2016
Commitments and Contingencies	(5) Commitments and Contingencies Operating Lease The Company rents its office, warehouse and laboratory facilities under an operating lease, which was originally set to expire on September 30, 2015. On August 25, 2015, the Company entered into an amendment extending the term of the operating lease for three years until September 30, 2018, with monthly base rent ranging from $18,925 to $20,345. Total rent expense recognized for each of the three month periods ended June 30, 2016 and 2015 was $58,905 and $67,718, and for each of the six month periods ended June 30, 2016 and 2015 was $117,810 and $135,436.. At June 30, 2016, future minimum payments under the lease are as follows: Year ending December 31: Remaining six months in 2016 $ 117,810 2017 235,620 2018 176,715 $ 530,145 Product Liability Claims The Company is exposed to product liability claims that are inherent in the testing, production, marketing and sale of medical devices. Management believes any losses that may occur from these matters are adequately covered by insurance, and the ultimate outcome of these matters will not have a material effect on the Company’s financial position or results of operations. The Company is not currently a party to any litigation and is not aware of any pending or threatened litigation that could have a material adverse effect on the Company’s business, operating results or financial condition. Clinical Trials The Company is evaluating the Maestro System in human clinical trials, including the EMPOWER trial and ReCharge trial. Both of these clinical trials require patients to be followed out to 60 months. The Company is required to pay for patient follow up visits only to the extent they occur. In the event a patient does not attend a follow up visit, the Company has no financial obligation. The Company is also required to pay for explants or revisions, including potential conversions of ReCharge control devices to active devices, should a patient request or be required to have one during the course of the clinical trials. The Company has no financial obligation unless an explant, revision or conversion is requested or required. Clinical trial costs are expensed as incurred.

Senior Amortizing Convertible N

Senior Amortizing Convertible Notes	6 Months Ended
	Jun. 30, 2016
Senior Amortizing Convertible Notes	(6) Senior Amortizing Convertible Notes On November 4, 2015, the Company entered into the Purchase Agreement to issue and sell to four institutional investors 7% senior amortizing convertible notes due 2017 in three separate closings. The Notes are convertible into shares of the Company’s common stock at a price equal to $4.35 per share with an aggregate principal amount of $25.0 million. Each Note was sold with a warrant to purchase a share of common stock (the Warrants) with an exercise price of $4.65 per share. The Company issued and sold Notes and Warrants for aggregate total proceeds of $12.5 million in two separate closings through March 31, 2016, and after entering into the First Amendment, which provided that the scheduled third closing would be split into two separate closings, issued and sold Notes and Warrants for aggregate total proceeds of $6.25 million in the Third Closing. The Company will issue and sell Notes and Warrants for aggregate total proceeds of up to $6.25 million in the Fourth Closing, which pursuant to the Second Amendment, is scheduled to occur no later than December 1, 2016. The Second Amendment provides that the Company may reduce the conversion price of the Notes from time to time in order to incentivize the holders of the Notes to convert their Notes into shares of the Company’s common stock. In addition, at the Fourth Closing, the holders of the Notes will be obligated to purchase at least 50% of the aggregate principal of the Notes they convert, either on a voluntary or installment conversion basis, on and after July 1, 2016, up to an aggregate principal amount of $6.25 million, although no holder will be obligated to purchase more Notes than originally scheduled in the First Amendment. Between July 1, 2016 and August 11, 2016, $2.6 million of aggregate principal amount of Notes were converted by holders of the Notes into approximately 14.1 million shares of the Company’s common stock. Description of the Notes The Notes are payable in monthly installments, accrue interest at a rate of 7.0% per annum from the date of issuance and will mature 24 months after the First Closing, unless converted or redeemed earlier. The Notes may be repaid, at the Company’s election, in either cash or shares of the Company’s common stock at a discount to the then-current market price. The Notes are also convertible from time to time, at the election of the holders, into shares of the Company’s common stock at an initial conversion price of $4.35 per share. The conversion price was adjusted to $1.09 per share on January 29, 2016, the 16 th The holder of each Note has the right to convert any portion of such Note unless the holder, together with its affiliates, beneficially owns in excess of 4.99% of the number of shares of the Company’s common stock outstanding immediately after giving effect to the conversion, as such percentage ownership is determined in accordance with the terms of the Notes. However, any holder may increase or decrease such percentage to any other percentage, but in no event above 9.99%, provided that any increase of such percentage will not be effective until 61 days after providing notice to the Company. The Company has determined that the conversion feature in the Notes requires bifurcation and liability classification and measurement, at fair value, and requires evaluation at each reporting period. Under Accounting Standards Codification (ASC) 825, Financial Instruments, the FASB provides an alternative to bifurcation and companies may instead elect fair value measurement for the entire instrument, including the debt and conversion feature. The Company has elected the fair value alternative in order to simplify its accounting and reporting of the Notes upon issuance. The fair value of the Warrants is recorded as a discount to the Notes and amortized to interest expense following the effective interest rate method over the term of the Notes. The First Closing occurred on November 9, 2015. At the First Closing, the Company issued and sold Notes with an aggregate principal amount of $1.5 million, along with Warrants exercisable for 117,520 shares. The Second Closing occurred on January 11, 2016 after the Company received approval of the offering by the Company’s stockholders and the satisfaction of certain customary closing conditions. At the Second Closing, the Company issued and sold Notes with an aggregate principal amount of $11.0 million, along with Warrants exercisable for 861,842 shares. The fair value of the Warrants issued on January 11, 2016 was determined to be $515,000 using a Black-Scholes valuation model and the following assumptions: (1) dividend yield of 0%; (2) expected volatility of 85.90%; (3) weighted average risk –free interest rate of 1.58%; and (4) expected life of 5.0 years. The Third Closing occurred on May 2, 2016 after the Company entered into the First Amendment and satisfied certain closing conditions. At the Third Closing, the Company issued and sold Notes with an aggregate principal amount of $6.25 million, along with Warrants exercisable for 489,684 shares. At the Fourth Closing, the Company will issue and sell Notes with an aggregate principal amount of up to $6.25 million, along with Warrants exercisable for 489,682 shares. The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the First Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at December 31, 2015 $ 65,217 $ 23,651 $ 88,868 56,967 Holder conversions during the quarter ended December 31, 2015 18,261 2,375 20,636 13,228 Balance, December 31, 2015 83,478 26,026 109,504 70,195 Installment amount at February 29, 2016 65,217 23,681 88,898 91,953 Installment amount at March 31,2016 65,217 14,827 80,044 88,960 Holder conversions during the quarter ended March 31, 2016 104,784 12,762 117,546 106,684 Balance, March 31, 2016 $ 318,696 $ 77,296 $ 395,992 357,792 Installment amount at April 30, 2016 65,217 13,853 79,070 101,764 Installment amount at May 31, 2016 65,217 13,082 78,299 148,467 Installment amount at June 30, 2016 54,217 11,275 65,492 251,320 Holder conversions during the quarter ended June 30, 2016 1,627 174 1,801 2,000 Balance, June 30, 2016 $ 504,974 $ 115,680 $ 620,654 861,343 The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the Second Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at March 2, 2016 $ 404,762 $ 149,300 $ 554,062 * Holder conversions during the quarter ended March 31, 2016 987,000 124,050 1,111,050 1,048,167 Balance, March 31, 2016 1,391,762 273,350 1,665,112 1,048,167 Installment amount at April 29, 2016 404,762 149,497 554,259 713,334 Installment amount at May 31, 2016 291,428 86,518 377,946 716,625 Installment amount at June 30, 2016 404,762 82,913 487,675 1,598,908 Holder conversions during the quarter ended June 30, 2016 25,373 2,995 28,368 29,000 Balance, June 30, 2016 $ 2,518,087 $ 595,273 $ 3,113,360 $ 4,106,034 The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the Third Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at June 30, 2016 $ 212,158 $ 90,659 $ 302,817 $ 1,162,000 Balance, June 30, 2016 $ 212,158 $ 90,659 $ 302,817 $ 1,162,000 * Cash payments Description of the Warrants Each Warrant is exercisable immediately and for a period of 60 months from the date of the issuance of the Warrant. Upon the completion of the Fourth Closing, the Warrants will entitle the holders of the Warrants to purchase, in aggregate, 1,958,728 shares of the Company’s common stock, subject to certain adjustments. The Warrants were initially exercisable at an exercise price equal to $4.65, subject to adjustment on the eighteen month anniversary of issuance, and certain other adjustments. The exercise price and number of shares of common stock issuable on the exercise of the Warrants is subject to adjustment upon the issuance of any shares of common stock or securities convertible into shares of common stock below the then-existing exercise price, with certain exceptions, and in the event of any stock split, reverse stock split, recapitalization, reorganization or similar transaction. The holder of each Warrant does not have the right to exercise any portion of such Warrant if the holder, together with its affiliates, beneficially owns in excess of 4.99% of the number of shares of the Company’s common stock outstanding immediately after giving effect to the exercise, as such percentage ownership is determined in accordance with the terms of the Warrants. However, any holder may increase or decrease such percentage to any other percentage, but in no event above 9.99%, provided that any increase of such percentage will not be effective until 61 days after providing notice to the Company. The exercise price of the Warrants issued November 9, 2015 was reduced to $1.09 per share on January 29, 2016, the 16 th

Stock-based Compensation

Stock-based Compensation	6 Months Ended
	Jun. 30, 2016
Stock-based Compensation	(7) Stock-based Compensation The fair value method of accounting for share-based payments is applied to all share-based payment awards issued to employees and where appropriate, nonemployees, unless another source of literature applies. When determining the measurement date of a nonemployee’s share-based payment award, the Company measures the stock options at fair value and remeasures such stock options to the current fair value until the performance date has been reached. Based on the application of these standards, stock-based compensation expense for stock-based awards under the Company’s Amended and Restated 2003 Stock Incentive Plan (the Plan) and inducement grants for the three and six months ended June 30, 2016 and 2015 was allocated to operating expenses and employees and nonemployees as follows: Three months ended Six months ended 2016 2015 2016 2015 Selling, general and administrative $ 581,857 $ 1,205,445 $ 1,421,634 $ 2,241,891 Research and development 172,267 343,264 424,978 678,894 Total $ 754,124 $ 1,548,709 $ 1,846,612 $ 2,920,785 Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Employees $ 752,996 $ 1,552,108 $ 1,843,188 $ 2,940,032 Nonemployees $ 1,128 (3,399 ) 3,424 (19,247 ) Total $ 754,124 $ 1,548,709 $ 1,846,612 $ 2,920,785 On June 27, 2016 the Company completed an option exchange offer to its employees whereby certain outstanding options to purchase shares of the Company’s common stock were tendered by employees in exchange for new options with the exercise price to be set at the then current market price of the Company’s common stock. Options to purchase 449,706 shares of the Company’s common stock, which included all the options eligible for exchange, were tendered by employees and cancelled by the Company. On the same date, options to purchase 75,819 shares of the Company’s common stock were issued with an exercise price of $0.3325 per share, which was the Company’s closing stock price on June 27, 2016. Because the fair value of the tendered options immediately before the exchange approximated the fair value of the new options granted, no additional compensation expense was recognized. As of June 30, 2016 there was approximately $1.8 million of total unrecognized compensation costs, net of estimated forfeitures, related to employee unvested stock option awards, which are expected to be recognized over a weighted-average period of 3.26 years. The estimated grant-date fair values of the stock options were calculated using the Black-Scholes valuation model, based on the following assumptions for the three and six months ended June 30, 2016 and 2015: Employees Employees Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Risk-free interest rates 0.87%-1.34 % 1.49%-1.75 % 0.87%-1.64 % 1.49%-1.80 % Expected life 4.00-6.00 years 5.50-6.25 years 4.00-6.25 years 5.50-6.25 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 92.38%-96.10 % 83.36%-108.23 % 88.43%-96.10 % 83.36%-111.77 % Nonemployees Nonemployees Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Risk-free interest rates 0.89 % 0.02%-2.10 % 0.89%-1.11 % 0.02%-2.10 % Expected life 4.14 years 0.08-8.26 years 4.14-4.39 years 0.08-8.51 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 96.33 % 22.42%-132.01 % 92.41%-96.33 % 22.42%-132.01 % Option activity under the Plan for the six months ended June 30, 2016 was as follows: Outstanding Options Shares Available For Grant Number of Shares Weighted- Average Exercise Price Balance, December 31, 2015 296,579 1,018,752 $ 32.83 Shares reserved — — — Options granted (150,485 ) 150,485 0.65 Options exercised — — — Options cancelled 504,995 (504,995 ) 29.37 Balance, June 30, 2016 651,089 664,242 28.17 In addition to the stock options granted pursuant to the Plan, the Company has also granted inducement stock options in connection with the appointments of (i) Dan Gladney to the position of President and Chief Executive Officer on October 28, 2015, (ii) Nick Ansari to the position of Senior Vice President (SVP) of Sales on January 6, 2016, (iii) Peter DeLange to the position of SVP of Operations and Business Development on January 18, 2016 and (iv) Paul Hickey to the position of SVP of Marketing and Reimbursement on January 18, 2016. Mr. Gladney was granted an option to purchase 516,666 shares of the Company’s common stock as an inducement grant, with an exercise price of $3.75 per share, the closing price of the Company’s common stock on October 28, 2015. Mr. Delange was granted an option to purchase 166,667 shares of the Company’s common stock as an inducement grant, with an exercise price of $1.38 per share, the closing price of the Company’s common stock on January 18, 2016. Mr. Ansari was granted an option to purchase 106,667 shares of the Company’s common stock as an inducement grant, with an exercise price of $1.31 per share, the closing price of the Company’s common stock on January 19, 2016. Mr. Hickey was granted an option to purchase 106,667 shares of the Company’s common stock as an inducement grant, with an exercise price of $1.32 per share, the closing price of the Company’s common stock on January 22, 2016. Each of the inducement grants will vest as follows: 25% of the shares will vest as of one year from the date of the officer’s employment agreement, and the remaining 75% of the shares will then vest in equal 2.0833% installments each month thereafter for 36 months. The inducement options were not eligible for the option exchange program.

Stock Sales

Stock Sales	6 Months Ended
	Jun. 30, 2016
Stock Sales	(8) Stock Sales Sales Agreement—July 2015 On July 8, 2015, the Company closed a public offering, where it sold 2,133,333 units at an aggregate price of $7.50 per unit, for gross proceeds of $16.0 million before deducting estimated offering expenses of approximately $1.4 million, of which $532,000 was assigned to the warrants issued with each unit sold and was recognized immediately as interest expense in the condensed consolidated statements of operations as the warrants are exercisable upon issuance. Each unit consisted of: (A)(i) one share of common stock or (ii) one pre-funded Series C warrant to purchase one share of common stock at an exercise price equal to $7.50 per share (Series C Warrant); and (B) one Series A warrant to purchase one share of common stock at an exercise price initially equal to $9.00 per share (Series A Warrant). Each purchaser of a unit could elect to receive a Series C Warrant in lieu of a share of common stock. No Series C Warrants were issued. The Series A Warrants are exercisable for a period of 42 months from the closing date of the public offering. The exercise price and number of shares of common stock issuable on the exercise of the Series A Warrants are subject to adjustment upon the issuance of any shares of common stock or securities convertible into shares of common stock below the then-existing exercise price, with certain exceptions, and in the event of any stock split, reverse stock split, recapitalization, reorganization or similar transaction. The holder of the Series A Warrant does not have the right to exercise any portion of the Series A Warrant if the holder, together with its affiliates, would, subject to certain limited exceptions, beneficially own in excess of 9.99% of the Company’s common stock outstanding immediately after the exercise or 4.99% as may be elected by the purchaser. The exercise price of the Series A Warrants issued July 8, 2015 was reduced to $2.40 per share on November 9, 2015 as a result of the issuance of the Notes and was further reduced to $1.50 per share on December 31, 2015, $0.97 per share on January 29, 2016, and $0.88 on March 30, 2016, $0.26 on June 30, 2016, and $0.19 on August 1, 2016 after installment payments on the Notes were made. Sales Agreement—June 2014 On June 13, 2014, the Company entered into a sales agreement with Cowen and Company, LLC (Cowen) to sell shares of the Company’s common stock having aggregate gross sales proceeds of up to $25.0 million, from time to time, through an “at-the-market” equity offering program under which Cowen will act as the Company’s sales agent (the Cowen ATM). The Company will determine, at its sole discretion, the timing and number of shares to be sold under the Cowen ATM. The Company will pay Cowen a commission for its services in acting as agent in the sale of common stock equal to 3.0% of the gross sales price per share of all shares sold through it as agent under the sales agreement. As of June 30, 2016, the Company had sold 367,903 shares under the Cowen ATM at a weighted-average selling price of $20.60 per share for gross proceeds of $7.6 million before deducting offering expenses. There have been no shares sold under the Cowen ATM subsequent to June 30, 2016 through August 11, 2016. The Company is restricted from issuing shares under the Cowen ATM until November 9, 2016 per the terms of the Purchase Agreement (see Notes 2 and 7).

Summary of Significant Accoun15

Summary of Significant Accounting Policies (Policies)	6 Months Ended
	Jun. 30, 2016
Description of Business	Description of Business EnteroMedics Inc. (the Company) develops and sells implantable systems to treat obesity, metabolic diseases and other gastrointestinal disorders. The Company was incorporated in the state of Minnesota on December 19, 2002 and was reincorporated in Delaware on July 22, 2004. The Company is headquartered in St. Paul, Minnesota. In January 2006, the Company established EnteroMedics Europe Sárl, a wholly-owned subsidiary located in Switzerland. The Company’s board of directors and stockholders approved a 1-for-15 reverse split (the Reverse Stock Split) of the Company’s outstanding common stock that became effective after trading on January 6, 2016. The Reverse Stock Split did not change the par value of the Company’s stock or the number of preferred shares authorized by the Company’s Fifth Amended and Restated Certificate of Incorporation. An amendment to the Certificate of Incorporation was also approved in connection with the Reverse Stock Split to increase the number of shares of the Company’s common stock authorized for issuance to 150 million shares, effective immediately after the Reverse Stock Split on January 6, 2016. All share and per share amounts have been retroactively adjusted to reflect the Reverse Stock Split for all periods presented.
Risks and Uncertainties	Risks and Uncertainties The Company is focused on the design and development of medical devices that use neuroblocking technology to treat obesity, metabolic diseases and other gastrointestinal disorders and currently has approvals to commercially launch the Maestro Rechargeable System in the United States and in Australia, the European Economic Area and other countries that recognize the European CE Mark. The Company has devoted substantially all of its resources to recruiting personnel, developing its product technology, obtaining patents to protect its intellectual property and raising capital, and has recently commenced commercial operations in the United States deriving revenues from its primary business activity in 2015. The Company’s products require approval from the U.S. Food and Drug Administration (FDA) or corresponding foreign regulatory agencies prior to commercial sales. The Company received FDA approval on January 14, 2015 for vBloc Therapy, delivered via the Maestro Rechargeable System, and has begun a controlled commercial launch at select centers in the United States. The Maestro Rechargeable System has also received CE Mark and is listed on the Australian Register of Therapeutic Goods (ARTG). The medical device industry is characterized by frequent and extensive litigation and administrative proceedings over patent and other intellectual property rights. Whether a product infringes a patent involves complex legal and factual issues, the determination of which is often difficult to predict, and the outcome may be uncertain until the court has entered final judgment and all appeals are exhausted. The Company’s competitors may assert that its products or the use of the Company’s products are covered by U.S. or foreign patents held by them. The Company’s activities are subject to significant risks and uncertainties, including the ability to obtain additional financing, and there can be no assurance that the Company will be successful in obtaining additional financing on favorable terms, or at all. If adequate funds are not available, the Company may have to delay development or commercialization of products or license to third parties the rights to commercialize products or technologies that the Company would otherwise seek to commercialize.
Basis of Presentation	Basis of Presentation The Company has prepared the accompanying condensed consolidated financial statements in conformity with accounting principles generally accepted in the United States of America. The Company’s fiscal year ends on December 31. The accompanying condensed consolidated financial statements and notes thereto are unaudited. In the opinion of the Company’s management, these statements include all adjustments, which are of a normal recurring nature, necessary to present a fair presentation. Interim results are not necessarily indicative of results for a full year. The condensed consolidated balance sheet as of December 31, 2015 was derived from audited consolidated financial statements, but does not include all disclosures required by accounting principles generally accepted in the United States of America. The information included in this Form 10-Q should be read in conjunction with the Company’s Annual Report on Form 10-K for the year ended December 31, 2015.
Use of Estimates	Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Actual results could differ from those estimates.
Principles of Consolidation	Principles of Consolidation The accompanying condensed consolidated financial statements include the accounts of the Company and its wholly-owned subsidiary. All intercompany transactions and accounts have been eliminated in consolidation.
Fair Value of Financial Instruments	Fair Value of Financial Instruments Carrying amounts of certain of the Company’s financial instruments, including cash and cash equivalents, accounts receivable, prepaid expenses and other current assets, accounts payable and accrued liabilities approximate fair value due to their short maturities. The Company’s common stock warrants are required to be reported at fair value and the Company has elected to report its senior amortizing convertible notes at fair value. The fair values of common stock warrants and investments in debt and equity securities, if any, are disclosed in Note 3. The fair value of the Company’s senior amortizing convertible notes is disclosed in Notes 3 and 7.
Common Stock Warrant Liability	Common Stock Warrant Liability Common stock warrants that were issued in connection with the July 8, 2015 public offering and the November 9, 2015, January 11, 2016 and May 2, 2016 senior amortizing convertible notes are classified as a liability in the condensed consolidated balance sheets, as the common stock warrants issued provide for certain anti-dilution protections in the event shares of common stock or securities convertible into shares of common stock are issued below the then-existing exercise price. The fair value of these common stock warrants is re-measured at each financial reporting period and immediately before exercise, with any changes in fair value being recognized as a component of other income (expense) in the condensed consolidated statements of operations.
Cash and Cash Equivalents	Cash and Cash Equivalents The Company considers highly liquid investments generally with maturities of 90 days or less when purchased to be cash equivalents. Cash equivalents are stated at cost, which approximates market value. The Company’s cash equivalents are primarily in money market funds and certificates of deposit. The Company deposits its cash and cash equivalents in high-quality credit institutions.
Short-Term Investments	Short-Term Investments The Company considers all investments with maturities greater than three months and less than one year at the time of purchase as short-term investments and classifies them as either available for sale or held to maturity. The Company also considers certain investments with maturities greater than one year but which are also held for liquidity purposes and are available for sale as short-term investments. Available-for-sale securities are carried at fair value based on quoted market prices, with the unrealized gains and losses included in other comprehensive income within stockholders’ equity in the condensed consolidated balance sheets. Realized gains and losses and declines in value judged to be other than temporary on available-for-sale securities are included in interest and other income. Interest and dividends on securities classified as available for sale are included in interest income. The cost of securities sold is based on the specific identification method. Short-term investments in debt securities which the Company has the positive intent and ability to hold to maturity are reported at cost, adjusted for premiums and discounts that are recognized in interest income, using the interest method, over the period to maturity. Unrealized losses on held-to-maturity securities reflecting a decline in value determined to be other than temporary are charged to income.
Inventory	Inventory The Company accounts for inventory at the lower of cost or market and records any long-term inventory as other assets in the condensed consolidated balance sheets.
Property and Equipment, Net	Property and Equipment, Net Property and equipment are stated at cost less accumulated depreciation and amortization. Depreciation of property and equipment is computed using the straight-line method over their estimated useful lives of five to seven years for furniture and equipment and three to five years for computer hardware and software. Leasehold improvements are amortized on a straight-line basis over the lesser of their useful life or the term of the lease. Upon retirement or sale, the cost and related accumulated depreciation or amortization are removed from the condensed consolidated balance sheets and the resulting gain or loss is reflected in the condensed consolidated statements of operations. Repairs and maintenance are expensed as incurred.
Impairment of Long-Lived Assets	Impairment of Long-Lived Assets The Company evaluates its long-lived assets for impairment by comparison of the carrying amounts to future net undiscounted cash flows expected to be generated by such assets when events or changes in circumstances indicate the carrying amount of an asset may not be recoverable. Should an impairment exist, the impairment loss would be measured based on the excess carrying value of the asset over the asset’s fair value or estimates of future discounted cash flows. The Company has not identified any such impairment losses to date.
Income Taxes	Income Taxes Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carry-forwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance for deferred income tax assets is recorded when it is more likely than not that some portion or all of the deferred income tax assets will not be realized. The Company has provided a full valuation allowance against the gross deferred tax assets. The Company’s policy is to classify interest and penalties related to income taxes as income tax expense in the condensed consolidated statements of operations.
Medical Device Excise Tax	Medical Device Excise Tax On January 14, 2015, the Company received FDA approval for vBloc Therapy, delivered via the Maestro Rechargeable System, and starting in the second quarter of 2015 revenues were generated from sales in the United States. As a result, the Company is now required to pay a quarterly Medical Device Tax which is a part of the Affordable Care Act, which imposes a 2.3% excise tax on the sale of certain medical devices by device manufactures, producers or importers. The excise tax was effective on sales of devices made after December 31, 2012. The Company records the Medical Device Tax as an operating expense in the condensed consolidated statements of operations. A moratorium was placed on the Medical Device Tax for 2016 and 2017.
Comprehensive Loss	Comprehensive Loss Comprehensive loss is defined as the change in equity of a company during a period from transactions and other events and circumstances excluding transactions resulting from investment owners and distributions to owners. There was no difference from reported net loss for the three and six months ended June 30, 2016 and 2015.
Revenue Recognition	Revenue Recognition Revenue is recognized when persuasive evidence of an arrangement exists, title or risk of loss has passed, the selling price is fixed or determinable and collection is reasonably assured. Products are sold through direct sales or medical device distributors and revenue is recognized upon sale to a bariatric center of excellence or a medical device distributor when no right of return or price protection exists. Terms of sales to international distributors are generally EXW, reflecting that goods are shipped “ex works,” in which risk of loss is assumed by the distributor at the shipping point. A provision for returns is recorded only if product sales provide for a right of return. No provision for returns was recorded for the three and six months ended June 30, 2016 and 2015, as the product sales recorded did not provide for rights of return.
Research and Development Expenses	Research and Development Expenses Research and development expenses are charged to expense as incurred. Research and development expenses include, but are not limited to, product development, clinical trial expenses, including supplies, devices, explants and revisions, quality assurance, regulatory expenses, payroll and other personnel expenses, materials and consulting costs.
Net Loss Per Share	Net Loss Per Share Basic net loss per share is computed by dividing net loss by the weighted-average number of common shares outstanding during the period. Diluted net loss per share is based on the weighted-average common shares outstanding during the period plus dilutive potential common shares calculated using the treasury stock method. Such potentially dilutive shares are excluded when the effect would be to reduce a net loss per share. The Company’s potential dilutive shares, which include outstanding common stock options and warrants, have not been included in the computation of diluted net loss per share for all periods as the result would be anti-dilutive. The following table sets forth the computation of basic and diluted net loss per share for the three and six months ended June 30, 2016 and 2015: Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Numerator: Net loss $ (4,995,165 ) $ (7,403,762 ) $ (12,403,927 ) $ (14,577,785 ) Denominator for basic and diluted net loss per share: Weighted-average common shares outstanding 10,297,589 4,960,292 9,078,837 4,904,984 Net loss per share—basic and diluted $ (0.49 ) $ (1.49 ) $ (1.37 ) $ (2.97 ) The following table sets forth the potential shares of common stock that are not included in the calculation of diluted net loss per share because to do so would be anti-dilutive as of the end of each period presented: June 30, 2016 2015 Stock options outstanding 1,934,796 15,483,514 Warrants to purchase common stock 4,062,571 24,199,705
Recently Issued or Adopted Accounting Standards	Recently Issued or Adopted Accounting Standards In March 2016, the Financial Accounting Standards Board (FASB) issued Compensation-Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting (Accounting Standards Update No. 2016-09 (ASU 2016-09)) In May 2014, FASB issued Revenue from Contracts with Customers, Topic 606 (Accounting Standards Update No. 2014-09 (ASU 2014-09)) There have been no other significant changes in recent accounting pronouncements during the six months ended June 30, 2016 as compared to the recent accounting pronouncements described in the Company’s Annual Report on Form 10-K for the year ended December 31, 2015.

Summary of Significant Accoun16

Summary of Significant Accounting Policies (Tables)	6 Months Ended
	Jun. 30, 2016
Computation of Basic and Diluted Net Loss per Share	The following table sets forth the computation of basic and diluted net loss per share for the three and six months ended June 30, 2016 and 2015: Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Numerator: Net loss $ (4,995,165 ) $ (7,403,762 ) $ (12,403,927 ) $ (14,577,785 ) Denominator for basic and diluted net loss per share: Weighted-average common shares outstanding 10,297,589 4,960,292 9,078,837 4,904,984 Net loss per share—basic and diluted $ (0.49 ) $ (1.49 ) $ (1.37 ) $ (2.97 )
Antidilutive Securities	The following table sets forth the potential shares of common stock that are not included in the calculation of diluted net loss per share because to do so would be anti-dilutive as of the end of each period presented: June 30, 2016 2015 Stock options outstanding 1,934,796 15,483,514 Warrants to purchase common stock 4,062,571 24,199,705

Short-term Investments and Fa17

Short-term Investments and Fair Value Measurements (Tables)	6 Months Ended
	Jun. 30, 2016
Summary of Fair Value Measurements of Senior Amortizing Convertible Notes and Common Stock Warrants	The following table summarizes fair value measurements of the Notes and the common stock warrants issued in 2015 and during the six months ended June 30, 2016 by level at June 30, 2016: Level 1 Level 2 Level 3 Total Senior amortizing convertible notes $ 14,335,000 $ 14,335,000 Common stock warrants $ 463,422 463,422 Total $ 463,422 $ 14,335,000 $ 14,798,422
Warrant Liability
Schedule Of Assumption used to Calculate Fair Value	The fair value was calculated using the following assumptions: July 2015 Warrants November 2015 Warrants June 30, 2016 December 31, 2015 June 30, 2016 December 31, 2015 Risk-free interest rates 0.71 % 1.31 % 1.01 % 1.76 % Expected life 30 months 36 months 52 months 58 months Expected dividends 0 % 0 % 0 % 0 % Expected volatility 93.04 % 97.94 % 94.99 % 86.27 % January 2016 Warrants May 2016 Warrants June 30, 2016 January 11, 2016 June 30, 2016 May 2, 2016 Risk-free interest rates 1.01 % 1.58 % 1.01 % 1.32 % Expected life 54 months 60 months 58 months 60 months Expected dividends 0 % 0 % 0 % 0 % Expected volatility 93.53 % 85.90 % 92.31 % 89.28 %
Senior Amortizing Convertible Notes
Schedule Of Assumption used to Calculate Fair Value	The fair values were calculated using a Binomial Lattice model and the following assumptions: November 2015 Notes January 2016 Notes June 30, 2016 December 31, 2015 June 30, 2016 January 11, 2016 Risk-free interest rates 0.54 % 1.11 % 0.54 % 1.01 % Expected life 1.36 years 1.86 years 1.36 years 1.83 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 68.0 % 57.5 % 68.0 % 60.0 % Fair value per share of common stock $ 0.29 $ 1.95 $ 0.29 $ 1.33 May 2016 Notes June 30, 2016 May 2, 2016 Risk-free interest rates 0.54 % 0.69 % Expected life 1.36 years 1.52 years Expected dividends 0 % 0 % Expected volatility 68.0 % 65.0 % Fair value per share of common stock $ 0.29 $ 0.80

Inventory (Tables)

Inventory (Tables)	6 Months Ended
	Jun. 30, 2016
Current Inventory	Current inventory consists of the following as of: June 30, 2016 December 31, 2015 Raw materials $ 626,725 $ 576,898 Work-in-process 1,310,121 1,066,345 Finished goods 20,975 43,081 Inventory $ 1,957,821 $ 1,686,324

Commitments and Contingencies (

Commitments and Contingencies (Tables)	6 Months Ended
	Jun. 30, 2016
Future Minimum Payments under Lease	At June 30, 2016, future minimum payments under the lease are as follows: Year ending December 31: Remaining six months in 2016 $ 117,810 2017 235,620 2018 176,715 $ 530,145

Senior Amortizing Convertible20

Senior Amortizing Convertible Notes (Tables)	6 Months Ended
	Jun. 30, 2016
Summary of Installment Amounts and Additional Conversions	The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the First Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at December 31, 2015 $ 65,217 $ 23,651 $ 88,868 56,967 Holder conversions during the quarter ended December 31, 2015 18,261 2,375 20,636 13,228 Balance, December 31, 2015 83,478 26,026 109,504 70,195 Installment amount at February 29, 2016 65,217 23,681 88,898 91,953 Installment amount at March 31,2016 65,217 14,827 80,044 88,960 Holder conversions during the quarter ended March 31, 2016 104,784 12,762 117,546 106,684 Balance, March 31, 2016 $ 318,696 $ 77,296 $ 395,992 357,792 Installment amount at April 30, 2016 65,217 13,853 79,070 101,764 Installment amount at May 31, 2016 65,217 13,082 78,299 148,467 Installment amount at June 30, 2016 54,217 11,275 65,492 251,320 Holder conversions during the quarter ended June 30, 2016 1,627 174 1,801 2,000 Balance, June 30, 2016 $ 504,974 $ 115,680 $ 620,654 861,343 The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the Second Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at March 2, 2016 $ 404,762 $ 149,300 $ 554,062 * Holder conversions during the quarter ended March 31, 2016 987,000 124,050 1,111,050 1,048,167 Balance, March 31, 2016 1,391,762 273,350 1,665,112 1,048,167 Installment amount at April 29, 2016 404,762 149,497 554,259 713,334 Installment amount at May 31, 2016 291,428 86,518 377,946 716,625 Installment amount at June 30, 2016 404,762 82,913 487,675 1,598,908 Holder conversions during the quarter ended June 30, 2016 25,373 2,995 28,368 29,000 Balance, June 30, 2016 $ 2,518,087 $ 595,273 $ 3,113,360 $ 4,106,034 The following table summarizes the installment amounts and additional conversions by the holders of the Notes issued at the Third Closing through June 30, 2016: Principal Interest Total Common Shares Installment amount at June 30, 2016 $ 212,158 $ 90,659 $ 302,817 $ 1,162,000 Balance, June 30, 2016 $ 212,158 $ 90,659 $ 302,817 $ 1,162,000 * Cash payments

Stock-based Compensation (Table

Stock-based Compensation (Tables)	6 Months Ended
	Jun. 30, 2016
Summary of Operating Expenses and Employee and Nonemployees	Based on the application of these standards, stock-based compensation expense for stock-based awards under the Company’s Amended and Restated 2003 Stock Incentive Plan (the Plan) and inducement grants for the three and six months ended June 30, 2016 and 2015 was allocated to operating expenses and employees and nonemployees as follows: Three months ended Six months ended 2016 2015 2016 2015 Selling, general and administrative $ 581,857 $ 1,205,445 $ 1,421,634 $ 2,241,891 Research and development 172,267 343,264 424,978 678,894 Total $ 754,124 $ 1,548,709 $ 1,846,612 $ 2,920,785 Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Employees $ 752,996 $ 1,552,108 $ 1,843,188 $ 2,940,032 Nonemployees $ 1,128 (3,399 ) 3,424 (19,247 ) Total $ 754,124 $ 1,548,709 $ 1,846,612 $ 2,920,785
Stock Option Valuation Assumptions	The estimated grant-date fair values of the stock options were calculated using the Black-Scholes valuation model, based on the following assumptions for the three and six months ended June 30, 2016 and 2015: Employees Employees Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Risk-free interest rates 0.87%-1.34 % 1.49%-1.75 % 0.87%-1.64 % 1.49%-1.80 % Expected life 4.00-6.00 years 5.50-6.25 years 4.00-6.25 years 5.50-6.25 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 92.38%-96.10 % 83.36%-108.23 % 88.43%-96.10 % 83.36%-111.77 % Nonemployees Nonemployees Three months ended June 30, Six months ended June 30, 2016 2015 2016 2015 Risk-free interest rates 0.89 % 0.02%-2.10 % 0.89%-1.11 % 0.02%-2.10 % Expected life 4.14 years 0.08-8.26 years 4.14-4.39 years 0.08-8.51 years Expected dividends 0 % 0 % 0 % 0 % Expected volatility 96.33 % 22.42%-132.01 % 92.41%-96.33 % 22.42%-132.01 %
Summary of Stock Option Activity	Option activity under the Plan for the six months ended June 30, 2016 was as follows: Outstanding Options Shares Available For Grant Number of Shares Weighted- Average Exercise Price Balance, December 31, 2015 296,579 1,018,752 $ 32.83 Shares reserved — — — Options granted (150,485 ) 150,485 0.65 Options exercised — — — Options cancelled 504,995 (504,995 ) 29.37 Balance, June 30, 2016 651,089 664,242 28.17

Summary of Significant Accoun22

Summary of Significant Accounting Policies - Additional Information (Detail)	6 Months Ended
	Jun. 30, 2016USD ($)shares	Jan. 06, 2016shares	Dec. 31, 2015shares	Jun. 30, 2015USD ($)
Schedule Of Significant Accounting Policies [Line Items]
Common stock, reverse split ratio		0.0667
Common stock authorized for issuance | shares	150,000,000	150,000,000	13,333,333
Cash equivalents maturity period	90 days
Excise tax rate on medical devices	2.30%
Provision for returns | $	$ 0			$ 0
Minimum
Schedule Of Significant Accounting Policies [Line Items]
Short term investment maturity period	3 months
Maximum
Schedule Of Significant Accounting Policies [Line Items]
Short term investment maturity period	1 year
Furniture and Fixtures | Minimum
Schedule Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives	5 years
Furniture and Fixtures | Maximum
Schedule Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives	7 years
Computer hardware and software | Minimum
Schedule Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives	3 years
Computer hardware and software | Maximum
Schedule Of Significant Accounting Policies [Line Items]
Property and equipment estimated useful lives	5 years

Computation of Basic and Dilute

Computation of Basic and Diluted Net Loss Per Share (Detail) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Numerator:
Net loss	$ (4,995,165)	$ (7,403,762)	$ (12,403,927)	$ (14,577,785)
Denominator for basic and diluted net loss per share:
Weighted-average common shares outstanding	10,297,589	4,960,292	9,078,837	4,904,984
Net loss per share-basic and diluted	$ (0.49)	$ (1.49)	$ (1.37)	$ (2.97)

Potential Shares of Common Stoc

Potential Shares of Common Stock Not Included in Calculation of Diluted Net Loss per Share (Detail) - shares	6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015
Stock Option Outstanding
Anti-dilutive Securities
Anti-dilutive as of end of each period	1,934,796	15,483,514
Warrants to purchase common stock
Anti-dilutive Securities
Anti-dilutive as of end of each period	4,062,571	24,199,705

Liquidity and Management's Pl25

Liquidity and Management's Plans - Additional Information (Detail) - USD ($)	1 Months Ended
	May 31, 2016	Dec. 31, 2016	Jun. 30, 2016	May 02, 2016	Jan. 11, 2016	Dec. 31, 2015	Nov. 09, 2015	Nov. 04, 2015	Jun. 30, 2015	Dec. 31, 2014
Liquidity and Managements Plans [Line Items]
Cash and cash equivalents			$ 11,517,041			$ 7,927,240			$ 4,798,940	$ 11,619,167
Nasdaq Stock Market
Liquidity and Managements Plans [Line Items]
Minimum stockholders' Equity requirement	$ 2,500,000
Minimum bid price requirement	$ 1
Period Granted To Regain Compliance With Stockholders Equity Requirement	180 days
Additional Period to Be Granted If Fails to Regain Compliance with Minimum Bid Requirement Prior to Expiration Period	180 days
Senior Amortizing Convertible Note
Liquidity and Managements Plans [Line Items]
Senior amortizing convertible notes issued								$ 25,000,000
Senior Amortizing Convertible Note | First closing
Liquidity and Managements Plans [Line Items]
Senior amortizing convertible notes issued							$ 1,500,000
Senior Amortizing Convertible Note | First closing | Amendment
Liquidity and Managements Plans [Line Items]
Senior amortizing convertible notes issued				$ 6,250,000
Senior Amortizing Convertible Note | Second closing
Liquidity and Managements Plans [Line Items]
Senior amortizing convertible notes issued					$ 11,000,000
Scenario, Forecast | Senior Amortizing Convertible Note | Second closing | Amendment
Liquidity and Managements Plans [Line Items]
Senior amortizing convertible notes issued		$ 6,250,000

Short - term Investment and Fai

Short - term Investment and Fair Value Measurements - Additional Information (Detail) - USD ($)	3 Months Ended	6 Months Ended
	Jun. 30, 2016	Jun. 30, 2016	May 02, 2016	Jan. 11, 2016	Dec. 31, 2015
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Senior amortizing convertible notes principal and interest converted into shares of common stock		$ 3,200,000
Gain(losses) resulting from conversion of senior amortizing convertible notes	$ 1,208,594	709,026
Fair value of outstanding convertible notes	14,335,000	14,335,000
First closing
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of outstanding convertible notes	942,000	942,000			$ 1,300,000
Second closing
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of outstanding convertible notes	7,900,000	7,900,000		$ 9,900,000
Third closing
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of outstanding convertible notes	5,500,000	5,500,000	$ 6,000,000
Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	463,422	463,422
Warrants Issued July 8, 2015 | Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	352,206	352,206			2,759,583
Warrants Issued November 9, 2015 | Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	15,442	15,442			$ 118,234
Warrants Issued January 11, 2016 | Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	54,125	54,125		$ 515,157
Warrants Issued May 2, 2016 | Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	$ 32,883	$ 32,883	$ 150,195

Series A Warrants Fair Value Ca

Series A Warrants Fair Value Calculated Using Black-Scholes Valuation Model (Detail)	May 02, 2016	Jan. 11, 2016	Jun. 30, 2016	Dec. 31, 2015
Warrants Issued July 8, 2015
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates			0.71%	1.31%
Expected life			30 months	36 months
Expected dividends			0.00%	0.00%
Expected volatility			93.04%	97.94%
Warrants Issued November 9, 2015
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates			1.01%	1.76%
Expected life			52 months	58 months
Expected dividends			0.00%	0.00%
Expected volatility			94.99%	86.27%
Warrants Issued January 11, 2016
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates		1.58%	1.01%
Expected life		60 months	54 months
Expected dividends		0.00%	0.00%
Expected volatility		85.90%	93.53%
Warrants Issued May 2, 2016
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates	1.32%		1.01%
Expected life	60 months		58 months
Expected dividends	0.00%		0.00%
Expected volatility	89.28%		92.31%

Summary of Fair Value Measureme

Summary of Fair Value Measurements of Senior Amortizing Convertible Notes and Common Stock Warrants (Detail)	Jun. 30, 2016USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Senior amortizing convertible notes	$ 14,335,000
Total	14,798,422
Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	463,422
Level 2
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Total	463,422
Level 2 | Common Stock
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair value of warrants	463,422
Level 3
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Senior amortizing convertible notes	14,335,000
Total	$ 14,335,000

Schedule of Fair Value Assumpti

Schedule of Fair Value Assumption Calculated Using Binomial Lattice Model (Detail) - $ / shares	May 02, 2016	Jan. 11, 2016	Jun. 30, 2016	Dec. 31, 2015
November Twenty Fifteen Notes
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates			0.54%	1.11%
Expected life			1 year 4 months 10 days	1 year 10 months 10 days
Expected dividends			0.00%	0.00%
Expected volatility			68.00%	57.50%
Fair value per share of common stock			$ 0.29	$ 1.95
January Twenty Sixteen Notes
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates		1.01%	0.54%
Expected life		1 year 9 months 29 days	1 year 4 months 10 days
Expected dividends		0.00%	0.00%
Expected volatility		60.00%	68.00%
Fair value per share of common stock		$ 1.33	$ 0.29
May Twenty Sixteen Notes
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]
Risk-free interest rates	0.69%		0.54%
Expected life	1 year 6 months 7 days		1 year 4 months 10 days
Expected dividends	0.00%		0.00%
Expected volatility	65.00%		68.00%
Fair value per share of common stock	$ 0.80		$ 0.29

Inventory - Additional Informat

Inventory - Additional Information (Detail) - USD ($)	Jun. 30, 2016	Dec. 31, 2015
Inventory [Line Items]
Long-term inventory	$ 609,000	$ 519,000

Current Inventory (Detail)

Current Inventory (Detail) - USD ($)	Jun. 30, 2016	Dec. 31, 2015
Inventory [Line Items]
Raw materials	$ 626,725	$ 576,898
Work-in-process	1,310,121	1,066,345
Finished goods	20,975	43,081
Inventory	$ 1,957,821	$ 1,686,324

Commitments and Contingencies -

Commitments and Contingencies - Additional Information (Detail) - USD ($)	Aug. 25, 2015	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Loss Contingencies [Line Items]
Operating lease agreement expiration date	Sep. 30, 2018	Sep. 30, 2018
Operating lease agreement term	3 years
Total rent expense		$ 58,905	$ 67,718	$ 117,810	$ 135,436
Number of months that require patients to be followed out in clinical trials				60 months
Minimum
Loss Contingencies [Line Items]
Operating lease, monthly base rent	$ 18,925
Maximum
Loss Contingencies [Line Items]
Operating lease, monthly base rent	$ 20,345

Future Minimum Lease Payment (D

Future Minimum Lease Payment (Detail)	Jun. 30, 2016USD ($)
Leases Future Minimum Payments [Line Items]
Remaining six months in 2016	$ 117,810
2,017	235,620
2,018	176,715
Operating Leases, Future Minimum Payments Due, Total	$ 530,145

Senior Amortizing Convertible34

Senior Amortizing Convertible Notes - Additional Information (Detail) - USD ($)	May 02, 2016	Jan. 11, 2016	Nov. 09, 2015	Nov. 04, 2015	Aug. 11, 2016	Mar. 31, 2016	Jun. 30, 2016	Mar. 31, 2016	Jun. 30, 2016	Dec. 31, 2015	Jan. 29, 2016
Debt Instrument [Line Items]
Convertible notes, per share price			$ 4.35	$ 4.35							$ 1.09
Exercise price	$ 4.65	$ 4.65	$ 4.65								$ 1.09
Convertible notes, interest rate			7.00%
Aggregate principal amount converted in to shares									$ 3,200,000
Convertible notes, maturity period			24 months
Issued warrant			1,958,728
Warrants issued, exercisable time period			60 months
Third closing
Debt Instrument [Line Items]
Share issued up on conversion							1,162,000
Second closing
Debt Instrument [Line Items]
Share issued up on conversion							4,106,034	1,048,167
First closing
Debt Instrument [Line Items]
Share issued up on conversion							861,343	357,792		70,195
Minimum
Debt Instrument [Line Items]
Common stock ownership percentage required to exercise warrants			4.99%
Period available for the percentage to be effective			61 days
Maximum
Debt Instrument [Line Items]
Common stock ownership percentage required to exercise warrants			9.99%
Senior Amortizing Convertible Note
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue				$ 25,000,000
Exercise price				$ 4.65
Proceeds from issuance of debt instrument including warrants				$ 12,500,000
Convertible notes, interest rate				7.00%
Senior convertible notes, maturity year				2,017
Senior Amortizing Convertible Note | Subsequent Event
Debt Instrument [Line Items]
Aggregate principal amount converted in to shares					$ 2,600,000
Share issued up on conversion					14,100,000
Senior Amortizing Convertible Note | Fourth closing
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue							$ 6,250,000		$ 6,250,000
Proceeds from issuance of debt instrument including warrants						$ 6,250,000
Issued warrant							489,682		489,682
Senior Amortizing Convertible Note | Third closing
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue	$ 6,250,000
Issued warrant	489,684
Senior Amortizing Convertible Note | Third closing | Amendment
Debt Instrument [Line Items]
Proceeds from issuance of debt instrument including warrants	$ 6,250,000
Senior Amortizing Convertible Note | Second closing
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue		$ 11,000,000
Issued warrant		861,842
Fair value of warrants		$ 515,000
Expected dividends		0.00%
Expected volatility		85.90%
Risk-free interest rates		1.58%
Expected life		5 years
Senior Amortizing Convertible Note | First closing
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue			$ 1,500,000
Issued warrant			117,520
Senior Amortizing Convertible Note | First closing | Amendment
Debt Instrument [Line Items]
Senior amortizing convertible notes to be issue	$ 6,250,000

Summary of Installment Amounts

Summary of Installment Amounts and Additional Conversions (Detail) - USD ($)	3 Months Ended		6 Months Ended	12 Months Ended
	Jun. 30, 2016	Mar. 31, 2016	Jun. 30, 2016	Dec. 31, 2015
Short-term Debt [Line Items]
Total			$ 3,373,265
First closing
Short-term Debt [Line Items]
Principal	$ 504,974	$ 318,696		$ 83,478
Interest	115,680	77,296		26,026
Total	$ 620,654	$ 395,992		$ 109,504
Common Shares	861,343	357,792		70,195
Second closing
Short-term Debt [Line Items]
Principal	$ 2,518,087	$ 1,391,762
Interest	595,273	273,350
Total	$ 3,113,360	$ 1,665,112
Common Shares	4,106,034	1,048,167
Third closing
Short-term Debt [Line Items]
Principal	$ 212,158
Interest	90,659
Total	$ 302,817
Common Shares	1,162,000
Installment Payments December 31, 2015 | First closing
Short-term Debt [Line Items]
Principal				$ 65,217
Interest				23,651
Total				$ 88,868
Common Shares				56,967
Installment Payments February 29, 2016 | First closing
Short-term Debt [Line Items]
Principal		$ 65,217
Interest		23,681
Total		$ 88,898
Common Shares		91,953
Installment Payments March 31, 2016 | First closing
Short-term Debt [Line Items]
Principal		$ 65,217
Interest		14,827
Total		$ 80,044
Common Shares		88,960
Installment Payments April 30, 2016 | First closing
Short-term Debt [Line Items]
Principal	$ 65,217
Interest	13,853
Total	$ 79,070
Common Shares	101,764
Installment Payments May 31, 2016 | First closing
Short-term Debt [Line Items]
Principal	$ 65,217
Interest	13,082
Total	$ 78,299
Common Shares	148,467
Installment Payments May 31, 2016 | Second closing
Short-term Debt [Line Items]
Principal	$ 291,428
Interest	86,518
Total	$ 377,946
Common Shares	716,625
Installment Payments June 30 , 2016 | First closing
Short-term Debt [Line Items]
Principal	$ 54,217
Interest	11,275
Total	$ 65,492
Common Shares	251,320
Installment Payments June 30 , 2016 | Second closing
Short-term Debt [Line Items]
Principal	$ 404,762
Interest	82,913
Total	$ 487,675
Common Shares	1,598,908
Installment Payments June 30 , 2016 | Third closing
Short-term Debt [Line Items]
Principal	$ 212,158
Interest	90,659
Total	$ 302,817
Common Shares	1,162,000
Installment Payments March 2, 2016 | Second closing
Short-term Debt [Line Items]
Principal		$ 404,762
Interest		149,300
Total		554,062
Installment Payments April 29, 2016 | Second closing
Short-term Debt [Line Items]
Principal	$ 404,762
Interest	149,497
Total	$ 554,259
Common Shares	713,334
Holder Conversions | First closing
Short-term Debt [Line Items]
Principal	$ 1,627	104,784		$ 18,261
Interest	174	12,762		2,375
Total	$ 1,801	$ 117,546		$ 20,636
Common Shares	2,000	106,684		13,228
Holder Conversions | Second closing
Short-term Debt [Line Items]
Principal	$ 25,373	$ 987,000
Interest	2,995	124,050
Total	$ 28,368	$ 1,111,050
Common Shares	29,000	1,048,167

Stock-Based Compensation Expens

Stock-Based Compensation Expense for Stock-Based Awards (Detail) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Stock-based compensation	$ 754,124	$ 1,548,709	$ 1,846,612	$ 2,920,785
Selling, general and administrative
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Stock-based compensation	581,857	1,205,445	1,421,634	2,241,891
Research and development
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Stock-based compensation	172,267	343,264	424,978	678,894
Employees
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Stock-based compensation	752,996	1,552,108	1,843,188	2,940,032
Nonemployees
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Stock-based compensation	$ 1,128	$ (3,399)	$ 3,424	$ (19,247)

Stock Options - Additional Info

Stock Options - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Millions	Jun. 27, 2016	Jun. 30, 2016
Schedule Of Stock Options [Line Items]
Common stock tendered by employees and canceled by the company	449,706
Common stock issued to employees	75,819
Exercise price of option to purchase	$ 0.3325
Total unrecognized compensation costs related to non-vested stock options		$ 1.8
Total unrecognized compensation costs related to non-vested stock options, weighted-average period of recognition		3 years 3 months 4 days
President and Chief Executive Officer
Schedule Of Stock Options [Line Items]
Award granted, shares		516,666
Award granted, exercise price per share		$ 3.75
Award granted, vesting installment percentage		2.0833%
Award vesting period		36 months
Senior Vice President of Operations and Business Development Mr. Delange
Schedule Of Stock Options [Line Items]
Award granted, shares		166,667
Award granted, exercise price per share		$ 1.38
Senior Vice President of Sales
Schedule Of Stock Options [Line Items]
Award granted, shares		106,667
Award granted, exercise price per share		$ 1.31
Senior Vice President of Marketing and Reimbursement
Schedule Of Stock Options [Line Items]
Award granted, shares		106,667
Award granted, exercise price per share		$ 1.32
Vest as of one year from the date of his employment agreement | President and Chief Executive Officer
Schedule Of Stock Options [Line Items]
Award granted, vesting percentage		25.00%
Vest in equal 2.0833% installments each month thereafter over the following 36 months | President and Chief Executive Officer
Schedule Of Stock Options [Line Items]
Award granted, vesting percentage		75.00%

Estimated Grant-Date Fair Value

Estimated Grant-Date Fair Values of Employee Stock Options (Detail)	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Employees
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Risk-free interest rate, minimum	0.87%	1.49%	0.87%	1.49%
Risk-free interest rate, maximum	1.34%	1.75%	1.64%	1.80%
Expected dividends	0.00%	0.00%	0.00%	0.00%
Expected volatility, minimum	92.38%	83.36%	88.43%	83.36%
Expected volatility, maximum	96.10%	108.23%	96.10%	111.77%
Employees | Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life	4 years	5 years 6 months	4 years	5 years 6 months
Employees | Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life	6 years	6 years 3 months	6 years 3 months	6 years 3 months
Nonemployees
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Risk-free interest rates	0.89%
Risk-free interest rate, minimum		0.02%	0.89%	0.02%
Risk-free interest rate, maximum		2.10%	1.11%	2.10%
Expected life	4 years 1 month 21 days
Expected dividends	0.00%	0.00%	0.00%	0.00%
Expected volatility	96.33%
Expected volatility, minimum		22.42%	92.41%	22.42%
Expected volatility, maximum		132.01%	96.33%	132.01%
Nonemployees | Minimum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life		29 days	4 years 1 month 21 days	29 days
Nonemployees | Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Expected life		8 years 3 months 4 days	4 years 4 months 21 days	8 years 6 months 4 days

Summary of Stock Option Activit

Summary of Stock Option Activity (Detail) - $ / shares	Jun. 27, 2016	Jun. 30, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Outstanding Options, Number of Shares, Options cancelled	(449,706)
Stock Incentive Plan 2003
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Shares Available For Grant, Beginning Balance		296,579
Shares Available For Grant, Shares reserved		0
Shares Available For Grant, Options granted		(150,485)
Shares Available For Grant, Options exercised		0
Shares Available For Grant, Options cancelled		504,995
Shares Available For Grant, Ending Balance		651,089
Outstanding Options, Number of Shares, Beginning Balance		1,018,752
Outstanding Options, Number of Shares, Shares reserved		0
Outstanding Options, Number of Shares, Options granted		150,485
Outstanding Options, Number of Shares, Options exercised		0
Outstanding Options, Number of Shares, Options cancelled		(504,995)
Outstanding Options, Number of Shares, Ending Balance		664,242
Outstanding Options, Weighted-Average Exercise Price, Beginning Balance		$ 32.83
Outstanding Options, Weighted-Average Exercise Price, Shares reserved		0
Outstanding Options, Weighted-Average Exercise Price, Options granted		0.65
Outstanding Options, Weighted-Average Exercise Price, Options exercised		0
Outstanding Options, Weighted-Average Exercise Price, Options cancelled		29.37
Outstanding Options, Weighted-Average Exercise Price, Ending Balance		$ 28.17

Stock Sales - Additional Inform

Stock Sales - Additional Information (Detail) - USD ($)	Jul. 08, 2015	Jun. 13, 2014	Jun. 30, 2016	Aug. 01, 2016	May 02, 2016	Mar. 30, 2016	Jan. 29, 2016	Jan. 11, 2016	Dec. 31, 2015	Nov. 09, 2015
Class of Stock [Line Items]
Public offering selling units	2,133,333
Shares issued, price per unit	$ 7.50
Gross proceeds before deducting estimate offering expenses	$ 16,000,000
Offering costs	$ 1,400,000
Exercise price					$ 4.65		$ 1.09	$ 4.65		$ 4.65
Beneficial ownership percentage	9.99%
Cowen and Company LLC
Class of Stock [Line Items]
Gross proceeds before deducting estimate offering expenses			$ 7,600,000
Commission or discount percentage on issue of shares		3.00%
Number of shares sold			367,903
Warrants to purchase common stock
Class of Stock [Line Items]
Offering costs	$ 532,000
Series C Warrants
Class of Stock [Line Items]
Exercise price	$ 7.50
Warrant issued	0
Series A Warrants
Class of Stock [Line Items]
Exercise price	$ 9		$ 0.26			$ 0.88	$ 0.97		$ 1.50	$ 2.40
Warrants exercisable period	42 months
Subsequent Event | Series A Warrants
Class of Stock [Line Items]
Exercise price				$ 0.19
Minimum
Class of Stock [Line Items]
Beneficial ownership percentage	4.99%
Maximum | Cowen and Company LLC
Class of Stock [Line Items]
Gross proceeds before deducting estimate offering expenses		$ 25,000,000
Weighted Average | Cowen and Company LLC
Class of Stock [Line Items]
Sale of stock, price per share			$ 20.60