| Document and Entity Information | May 24, 2022 |
| Cover [Abstract] | |
| Amendment Flag | false |
| Entity Central Index Key | 0001376339 |
| Document Type | 8-K |
| Document Period End Date | May 24, 2022 |
| Entity Registrant Name | MIMEDX GROUP, INC. |
| Entity Incorporation State Country Code | FL |
| Entity File Number | 001-35887 |
| Entity Tax Identification Number | 26-2792552 |
| Entity Address, Address Line One | 1775 West Oak Commons Ct., NE |
| Entity Address, City or Town | Marietta |
| Entity Address, State or Province | GA |
| Entity Address, Postal Zip Code | 30062 |
| City Area Code | (770) |
| Local Phone Number | 651-9100 |
| Written Communications | false |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock, $0.001 par value per share |
| Trading Symbol | MDXG |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
