Ladenburg Thalmann & Co. Inc.
999 Vanderbilt Beach Road, Suite 200
Naples, Florida 34108
October 3, 2018
VIA FACSIMILE AND EDGAR
U.S. Securities and Exchange Commission
Division of Corporation Finance
Washington, DC 20549
| Re: | AYTU BIOSCIENCE, INC. | |
| Registration Statement on Form S-1 (Registration No. 333-227243) | ||
| Concurrence in Acceleration Request |
Ladies and Gentlemen:
Ladenburg Thalmann & Co. Inc. (“Ladenburg”), as representative of the underwriters for the above-referenced offering, hereby concurs in the request by Aytu BioScience, Inc. that the effective date of the above-referenced registration statement be accelerated to 5:00 p.m. (Eastern Time), or as soon as practicable thereafter, on October 4, 2018, pursuant to Rule 461 under the Securities Act. Ladenburg affirms that it is aware of its obligations under the Securities Act in connection with this offering.
| Very truly yours, | ||
| LADENBURG THALMANN & CO. INC. | ||
| By: | /s/ Nicholas Stergis | |
| Name: Nicholas Stergis Title: Managing Director | ||
