Aytu BioPharma (AYTU) S-4 Registration of securities issued in business combination transactions

Exhibit 21.1

Subsidiaries and Jurisdiction of Incorporation/Formation

· Aytu Women’s Health, LLC (Delaware)

· Aytu Therapeutics, LLC (Delaware)

· Innovus Pharmaceuticals, Inc. (Nevada)

· Semprae Laboratories, Inc. (Delaware)

· Novalare, Inc. (Delaware)

· Supplement Hunt, Inc. (Nevada)

· Delta Prime Savings Club, Inc. (Nevada)

· Neutron Acquisition Sub, Inc. (Delaware)