NovaBay Pharmaceuticals (NBY) 10-Q 12 May 22 2022 Q1 Quarterly report Financial data

Document And Entity Information

Document And Entity Information - shares	3 Months Ended
	Mar. 31, 2022	May 10, 2022
Document Information [Line Items]
Entity Central Index Key	0001389545
Entity Registrant Name	NOVABAY PHARMACEUTICALS, INC.
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Document Fiscal Period Focus	Q1
Document Fiscal Year Focus	2022
Document Type	10-Q
Document Quarterly Report	true
Document Period End Date	Mar. 31, 2022
Document Transition Report	false
Entity File Number	001-33678
Entity Incorporation, State or Country Code	DE
Entity Tax Identification Number	68-0454536
Entity Address, Address Line One	2000 Powell Street, Suite 1150
Entity Address, City or Town	Emeryville
Entity Address, State or Province	CA
Entity Address, Postal Zip Code	94608
City Area Code	510
Local Phone Number	899-8800
Title of 12(b) Security	Common Stock, par value $0.01 per share
Trading Symbol	NBY
Security Exchange Name	NYSE
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Emerging Growth Company	false
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		52,618,364

Condensed Consolidated Balance

Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
ASSETS
Cash and cash equivalents	$ 5,641	$ 7,504
Accounts receivable, net of allowance for doubtful accounts ($0 at March 31, 2022 and December 31, 2021)	2,300	1,668
Inventory, net of allowance for excess and obsolete inventory and lower of cost or estimated net realizable value adjustments ($522 and $641 at March 31, 2022 and December 31, 2021, respectively)	3,785	3,220
Prepaid expenses and other current assets	752	778
Total current assets	12,478	13,170
Operating lease right-of-use assets	2,331	411
Property and equipment, net	187	193
Goodwill, Ending Balance	4,528	4,528
Other intangible assets, net	5,109	5,200
Other assets	161	476
TOTAL ASSETS	24,794	23,978
LIABILITIES AND STOCKHOLDERS' EQUITY
Accounts payable	1,556	1,045
Accrued liabilities	2,763	2,092
Line of credit	0	105
Operating lease liability	465	200
Total current liabilities	4,784	3,442
Operating lease liabilities-non-current	1,922	246
Warrant liability	0	9,558
Contingent earnout liability	342	561
Total liabilities	7,048	13,807
Commitments & contingencies (Note 12)
Stockholders' equity:
Preferred stock, $0.01 par value; 5,000 shares authorized; 13 and 14 issued and outstanding at March 31, 2022 and December 31, 2021, respectively	609	680
Common stock, $0.01 par value; 150,000 and 100,000 shares authorized, 51,419 and 47,766 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively	514	478
Additional paid-in capital	158,621	150,900
Accumulated deficit	(141,998)	(141,887)
Total stockholders' equity	17,746	10,171
TOTAL LIABILITIES AND STOCKHOLDERS' EQUITY	$ 24,794	$ 23,978

Condensed Consolidated Balanc_2

Condensed Consolidated Balance Sheets (Unaudited) (Parentheticals) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Accounts receivable, allowance for doubtful accounts	$ 0	$ 0
Inventory, allowance for excess and obsolete inventory and lower of cost or estimated net realizable value adjustments	$ 522	$ 641
Preferred stock, shares authorized (in shares)	5,000,000	5,000,000
Preferred stock, shares outstanding (in shares)	13,000	14,000
Preferred stock, shares issued (in shares)	13,000	14,000
Preferred stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, shares authorized (in shares)	150,000,000	100,000,000
Common stock, shares issued (in shares)	51,419,000	47,766,000
Common stock, shares outstanding (in shares)	51,419,000	47,766,000

Condensed Consolidated Statemen

Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Sales:
Total sales, net	$ 2,629	$ 1,807
Product cost of goods sold	1,113	455
Gross profit	1,516	1,352
Operating expenses:
Research and development	28	5
Sales and marketing	1,687	1,680
General and administrative	2,183	1,187
Total operating expenses	3,898	2,872
Operating loss	(2,382)	(1,520)
Unrealized gain on changes in fair value of warrant liability	2,056	0
Unrealized gain on changes in fair value of contingent liability	219	0
Other (expense) income, net	4	(2)
Loss before provision for income taxes	(111)	(1,518)
Provision for income taxes	0	0
Net loss and comprehensive loss	$ (111)	$ (1,518)
Net loss per share attributable to common stockholders (basic and diluted) (in dollars per share)	$ 0	$ (0.04)
Weighted-average shares of common stock used in computing net loss per share attributable to common stockholders (basic and diluted) (in shares)	50,088	41,782
Product [Member]
Sales:
Total sales, net	$ 2,623	$ 1,801
Product and Service, Other [Member]
Sales:
Total sales, net	$ 6	$ 6

Condensed Consolidated Statem_2

Condensed Consolidated Statements of Stockholders' Equity (Deficit) (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	Total
Balance (in shares) at Dec. 31, 2020	0	41,782
Balance at Dec. 31, 2020	$ 0	$ 418	$ 147,963	$ (136,063)	$ 12,318
Balance at Dec. 31, 2020	0	(418)	(147,963)	136,063	(12,318)
Net Loss	$ 0	$ 0	0	(1,518)	(1,518)
Conversion of Series B Non-Voting Preferred Stock to common stock					0
Stock-based compensation expense related to employee and director stock options			130		130
Balance (in shares) at Mar. 31, 2021	0	41,782
Balance at Mar. 31, 2021	$ 0	$ 418	148,146	(137,581)	10,983
Balance at Mar. 31, 2021	$ 0	$ (418)	(148,146)	137,581	(10,983)
Stock-based compensation expense related to non-employee stock options			53		53
Balance (in shares) at Dec. 31, 2021	14	47,766
Balance at Dec. 31, 2021	$ 680	$ 478	150,900	141,887	10,171
Balance at Dec. 31, 2021	(680)	(478)	(150,900)	(141,887)	(10,171)
Net Loss	0	0	0	(111)	(111)
Reclassification of Private Placement Warrants	$ 0	$ 0	7,502	0	7,502
Conversion of Series B Non-Voting Preferred Stock to common stock (in shares)	(1)	(3,653)
Conversion of Series B Non-Voting Preferred Stock to common stock	$ (71)				(71)
Conversion of Series B Non-Voting Preferred Stock to common stock (in shares)	1	3,653
Conversion of Series B Non-Voting Preferred Stock to common stock		$ 36	35
Stock-based compensation expense related to employee and director stock options			184		184
Balance (in shares) at Mar. 31, 2022	13	51,419
Balance at Mar. 31, 2022	$ 609	$ 514	158,621	141,998	17,746
Balance at Mar. 31, 2022	$ (609)	$ (514)	$ (158,621)	$ (141,998)	$ (17,746)

Condensed Consolidated Statem_3

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Operating activities:
Net Loss	$ (111)	$ (1,518)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	30	9
Amortization of intangible assets	91	0
Unrealized gain on changes in fair value of warrant liability	(2,056)	0
Decrease in fair value of contingent liability	(219)	0
Changes in operating assets and liabilities:
Accounts receivable	(632)	68
Inventory	(565)	(242)
Prepaid expenses and other current assets	26	(174)
Operating lease right-of-use assets	(1,920)	86
Other assets	(8)	0
Accounts payable and accrued liabilities	1,182	267
Operating lease liabilities	1,941	(98)
Net cash used in operating activities	(2,057)	(1,419)
Investing activities:
Purchases of property and equipment	(24)	(25)
Net cash used in investing activities	(24)	(25)
Financing activities:
Payment on the line of credit	(105)	0
Net cash used in financing activities	(105)	0
Net decrease in cash, cash equivalents, and restricted cash	(2,186)	(1,444)
Cash, cash equivalents and restricted cash, beginning of year	7,979	12,427
Cash, cash equivalents and restricted cash, end of period	5,793	10,983
Supplemental disclosure of cash flow information:
Interest paid	4	0
Addition of operating lease, right-of-use asset	2,039	0
Conversion of Series B Non-Voting Preferred Stock to common stock	71	0
Employees and Directors [Member] | Share-Based Payment Arrangement, Option [Member]
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense for options and stock issued	184	130
Nonemployees [Member] | Share-Based Payment Arrangement, Option [Member]
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation expense for options and stock issued	0	53
The 2019 Preferred Warrant and 2019 Common Warrant Liability [Member]
Supplemental disclosure of cash flow information:
Warrant liability transferred to equity	$ 7,502	$ 0

Note 1 - Organization

Note 1 - Organization	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]	1. ORGANIZATION NovaBay Pharmaceuticals, Inc. develops and sells scientifically-created and clinically-proven eyecare and skincare products. Our leading product, Avenova® Antimicrobial Lid and Lash Solution (“Avenova Spray”), is proven in laboratory testing to have broad antimicrobial properties as it removes foreign material including microorganisms and debris from the skin around the eye, including the eyelid. Avenova Spray is formulated with our proprietary, stable and pure form of hypochlorous acid and is cleared by the U.S. Food and Drug Administration (“FDA”) for sale in the United States. Avenova Spray is available direct to consumers through online distribution channels and is also often prescribed and dispensed by eyecare professionals for blepharitis and dry-eye disease. Other eyecare products offered under the Avenova eyecare brand include Novawipes by Avenova, Avenova Lubricant Eye Drops, Avenova Moist Heating Eye Compress, and the i-Chek. On November 5, 2021, ( 30 3, The Company was incorporated under the laws of the State of California on January 19, 2000, no July 1, 2002, February 2007, June 2010, 1 2 Liquidity Based primarily on the funds available at March 31, 2022, May 12, 2023. may may 19

Note 2 - Summary of Significant

Note 2 - Summary of Significant Accounting Policies	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Significant Accounting Policies [Text Block]	NOTE 2. Basis of Presentation The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”) and are expressed in U.S. dollars. In management’s opinion, the condensed consolidated financial statements include all normal and recurring adjustments that are considered necessary for the fair presentation of the Company’s financial position and operating results. Use of Estimates The preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the unaudited condensed consolidated financial statements and accompanying notes. These estimates include contract liabilities related to product sales, useful lives for property and equipment and related depreciation calculations, assumptions for valuing options and warrants, the fair value of contingent consideration, intangible assets, goodwill, stock-based compensation, income taxes and other contingencies as of March 31, 2022. These estimates are based on management’s best estimates and judgment. Actual results may Cash, Cash Equivalents, and Restricted Cash The Company considers all highly-liquid instruments with a stated maturity of three March 31, 2022 December 31, 2021, The following table provides a reconciliation of the cash, cash equivalents, and restricted cash reported in the condensed consolidated balance sheets that sum to the total of the same reported in the condensed consolidated statements of cash flows (in thousands): March 31, December 31, 2022 2021 Cash and cash equivalents $ 5,641 $ 7,504 Restricted cash included in other assets 152 475 Total cash, cash equivalents, and restricted cash in the condensed consolidated statements of cash flows $ 5,793 $ 7,979 The restricted cash amount included in other assets on the condensed consolidated balance sheets represents amounts held as certificates of deposit for long-term financing and lease arrangements as contractually required by our financial institution and landlord. Concentrations of Credit Risk and Major Partners Financial instruments that potentially subject us to significant concentrations of credit risk consist primarily of cash, cash equivalents and restricted cash. The Company maintains deposits of cash, cash equivalents and restricted cash with a highly-rated, major financial institution in the United States. Deposits in this bank may not During the three March 31, 2022 2021, three March 31, 2022, During the three March 31, 2022 2021, Three Months Ended March 31, 2022 2021 Avenova Spray $ 1,426 $ 1,575 DERMAdoctor 891 — NeutroPhase 148 — Other products 158 226 Total product revenue, net 2,623 1,801 Other revenue, net 6 6 Total sales, net $ 2,629 $ 1,807 During the three March 31, 2022 2021, No 10% three March 31, 2022 2021. three March 31, 2022 no three March 31, 2021. As of March 31, 2022 December 31, 2021, 10% March 31, December 31, Major distribution partner 2022 2021 Major U.S. Retailer 35 % 33 % Avenova Spray Pharmacy Distributor B 14 % 11 % Avenova Spray Pharmacy Distributor A 13 % 13 % The Company relies on seven not third may may not may 19 Fair Value of Financial Assets and Liabilities The Company’s financial instruments include cash and cash equivalents, restricted cash, accounts receivable, accounts payable, accrued liabilities, and contingent consideration. The Company’s cash and cash equivalents, accounts receivable, accounts payable, and accrued liabilities are carried at cost, which management believes approximates fair value due to the short-term nature of these instruments. The Company follows Accounting Standards Codification (“ASC”) 820, Fair Value Measurements and Disclosures three may Level 1 Level 2 Level 3 Categorization within the valuation hierarchy is based upon the lowest level of input that is significant to the fair value measurement. Allowance for Doubtful Accounts The Company charges bad debt expense and records an allowance for doubtful accounts when management believes it to be unlikely that specific invoices will be collected. Management identifies amounts due that are in dispute and believes are unlikely to be collected. Management recorded no reserve for accounts receivable at March 31, 2022 December 31, 2021. Inventory Inventory is comprised of ( 1 2 3 first first March 31, 2022 December 31, 2021, Property and Equipment, net Property and equipment are stated at cost, less accumulated depreciation and amortization. Depreciation is calculated using the straight-line method over the estimated useful lives of the related assets of five seven three five five seven The costs of normal maintenance, repairs, and minor replacements are expensed as incurred. Business Combinations We account for 805, Business Combinations The determination of estimated fair value requires us to make significant estimates and assumptions. These fair value determinations require judgment and involve the use of significant estimates and assumptions, including assumptions with respect to future cash inflows and outflows, discount rates, and asset lives, among other items. As a result, we may one Transaction costs associated with business combinations are expensed as they are incurred. Goodwill and Intangible Assets Goodwill represents the excess of the consideration transferred over the estimated fair value of assets acquired and liabilities assumed in a business combination. Intangible assets are measured at their respective fair values as of the acquisition date and may may one not March 31, 2022 December 31, 2021. Intangible Asset Fair Value (in thousands) Useful Life (in years) Amortization Method Customer relationships $ 290 7 Straight line Trade secrets / product formulations 2,890 9 Straight line Trade names 2,080 Indefinite N/A Goodwill 4,528 Indefinite N/A $ 9,788 Valuation of Contingent Consideration Resulting from a Business Combination In connection with certain acquisitions, we may Increases or decreases in fair value of the contingent consideration liabilities can result from updates to assumptions such as the expected timing or probability of achieving the specified milestones. Significant judgment is employed in determining these assumptions as of the acquisition date and for each subsequent period. Updates to assumptions could have a significant impact on our results of operations in any given period. Actual results may Impairment of Long-Lived Assets The Company accounts for long-lived assets, other than goodwill and intangible assets, and operating lease right-of-use assets in accordance with ASC 360, Property, Plant and Equipment may may not no not no March 31, 2022 December 31, 2021. Leases At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on the unique facts and circumstances present. Operating lease liabilities and their corresponding right-of-use assets are recorded based on the present value of lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not may The Company has elected to combine lease and non-lease components as a single component for all leases in which it is a lessee or a lessor. The lease expense is recognized over the expected term on a straight-line basis. Operating leases are recognized on the balance sheet as right-of-use assets, operating lease liabilities current and operating lease liabilities non-current. Comprehensive Income (Loss) ASC 220, Comprehensive Income, Revenue Recognition Revenue is recognized from sale of goods in accordance with ASC 606, Revenue from Contracts with Customers 606” 606, 606, five 606: i. identify the contract(s) with a customer; ii. identify the performance obligations in the contract; iii. determine the transaction price; iv. allocate the transaction price to the performance obligations in the contract; and v. recognize revenue when (or as) the entity satisfies performance obligations. Revenue is generated through the Company’s webstores, Avenova.com and DERMAdoctor.com, for Avenova Spray and DERMAdoctor direct to consumer sales which are recognized upon fulfillment, which generally occurs upon delivery of the related products to a third Revenue generated through Amazon.com and Walmart.com third The Company also generates Avenova Spray revenue through major pharmacy distribution partners. Product supply of Avenova Spray is the only performance obligation contained in these arrangements, and the Company recognizes product revenue upon transfer of control to its major distribution partners at the amount of consideration that the Company expects to be entitled to, generally upon delivery to the distributor on a “sell-in” basis. Upon recognition of product sales, contract liabilities are recorded for invoiced amounts that are subject to significant reversal, including product revenue allowances for cash consideration paid to customers for services, discounts, rebate programs, and product returns. The Company derives its rate of return from historical data and updates its return rate assumption quarterly. Payment for product supply is typically due 30 days after control transfers to the distributor. Revenue generated through the Company’s partner pharmacies is recognized when control of the product transfers to the end customer. Revenue for product sales to other retailers, such as Costco and CVS, is generally recognized upon transfer of control to the retailer, which generally occurs upon delivery of the products to a third Cost of Goods Sold Cost of goods sold includes third Research and Development Costs The Company charges research and development costs to expense as incurred. These costs include all costs associated with research, development and regulatory activities, including submissions to the Food and Drug Administration (the “FDA”). Patent Costs Patent costs, including legal expenses, are expensed in the period in which they are incurred. Patent expenses are included in general and administrative expenses in the consolidated statements of operations and comprehensive loss. Advertising Costs Advertising costs are expensed in the period in which the costs are incurred. Advertising expenses were $0.6 million and $0.7 million for the three March 31, 2022 2021, Stock-Based Compensation The Company’s stock-based compensation includes grants of stock options and restricted stock units (“RSUs”) to employees, consultants and non-employee directors. The expense associated with these grants is recognized in the Company’s consolidated statements of stockholders’ equity based on their fair values as they are earned under the applicable vesting terms. For stock options granted, the fair value of the stock options is estimated using a Black-Scholes option pricing model. See Note 15, Income Taxes The Company accounts for income taxes under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance is recognized if it is more likely than not not Common Stock Warrant Liabilities The Company accounts for common stock purchase warrants issued in connection with its equity offerings in accordance with the provisions of ASC 480, Distinguishing Liabilities from Equity 815, Derivatives and Hedging The Company accounts for common stock purchase warrants issued in connection with share-based compensation arrangements in accordance with the provisions of ASC 718, Stock Compensation, 480, Distinguishing Liabilities from Equity The Company classifies as equity any contracts that (i) require physical settlement or net-share settlement or (ii) give the Company a choice of net-cash settlement or settlement in its own shares (physical settlement or net-share settlement). The Company classifies as assets or liabilities any contracts that (i) require net-cash settlement (including a requirement to net-cash settle the contract if an event occurs and if that event is outside the control of the Company), (ii) give the counterparty a choice of net-cash settlement or settlement in shares (physical settlement or net-share settlement) or (iii) do not 718, Stock Compensation, For warrants that are classified as liabilities, the Company records the fair value of the warrants at each balance sheet date and records changes in the estimated fair value as a non-cash gain or loss in the consolidated statements of operations and comprehensive loss. The fair values of these warrants are determined using the Black-Scholes option pricing model, the Binomial Lattice (“Lattice”) valuation model, or the Monte Carlo simulation model where deemed appropriate. These values are subject to a significant degree of management’s judgment. Net Loss per Share The Company computes net loss per share by presenting both basic and diluted earnings (loss) per share (“EPS”). Basic EPS is computed by dividing net loss available to common stockholders by the weighted average number of common shares outstanding during the period. Diluted EPS gives effect to all dilutive potential common shares outstanding during the period, including stock options and warrants, using the treasury stock method. In computing diluted EPS, the average stock price for the period is used to determine the number of shares assumed to be purchased from the exercise of stock options or warrants. Potentially dilutive common share equivalents are excluded from the diluted EPS computation in net loss periods because their effect would be anti-dilutive. For the year ended December 31, 2021, not The following table sets forth the calculation of basic EPS and diluted EPS (in thousands, except per share amounts): Three Months Ended March 31, Numerator 2022 2021 Net loss $ (111 ) $ (1,518 ) Denominator Weighted average shares of common stock outstanding, basic and diluted 50,088 41,782 Net loss per share attributable to common stockholders, basic and diluted $ 0.00 $ (0.04 ) The following outstanding stock options and stock warrants were excluded from the diluted EPS computation as their effect would have been anti-dilutive (in thousands): Three Months Ended March 31, 2022 2021 Stock options 4,416 3,138 Stock warrants 44,582 7,082 48,998 10,220 Recent Accounting Pronouncements For information regarding recent accounting pronouncements that could affect our business, results of operations, financial condition, and liquidity, see Note 2, 10 December 31, 2021, March 29, 2022.

Note 3 - Business Combination

Note 3 - Business Combination	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Business Combination Disclosure [Text Block]	NOTE 3. On November 5, 2021, 100% two The Company funded the closing purchase price in part through the 2021 14, The Acquisition is accounted for as a business combination in accordance to ASC 805, Business Combinations The following table sets forth the final allocation of the purchase price for the DERMAdoctor Acquisition to the fair value of the identifiable tangible and intangible assets acquired and liabilities assumed from DERMAdoctor (in thousands): Fair Value Tangible net assets and liabilities: Cash and cash equivalents $ 12 Accounts receivable, net of allowance for doubtful accounts 1,015 Inventory, net of allowance 2,369 Prepaid expenses and other current assets 150 Property and equipment, net 62 Other intangible assets 54 Accounts payable (200 ) Accrued liabilities (683 ) Total net assets 2,779 Intangible Assets: Customer relationships 290 Trade secrets / product formulations 2,890 Trade names 2,080 Total intangible assets 5,260 Net assets acquired 8,039 Purchased consideration 12,561 Goodwill $ 4,528 Goodwill is primarily attributable to assembled workforce, expected synergies and other factors. The fair values of the identifiable intangible assets acquired at the date of the DERMAdoctor Acquisition are as follows (in thousands): Intangible Asset Fair Value Useful Life (in years) Amortization Method Customer relationships $ 290 7 Straight line Trade secrets / product formulations 2,890 9 Straight line Trade names 2,080 Indefinite N/A Goodwill 4,528 Indefinite N/A $ 9,788 The valuations of intangible assets incorporate significant unobservable inputs and require significant judgment and estimates, including the amount and timing of future cash flows. The Company recognized approximately $1.2 million of transaction costs in the year ended December 31, 2021. The Company’s management reviews financial results and manages the business on an aggregate basis in accordance with ASC 280. 1 2 20,

Note 4 - Fair Value Measurement

Note 4 - Fair Value Measurements	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Fair Value Disclosures [Text Block]	NOTE 4. The Company’s cash equivalents are classified within Level 1 1 As of December 31, 2021, 2021, 3 13, 14, The following table presents the Company's assets measured at fair value on a recurring basis as of March 31, 2022 ( Fair Value Measurements Using Balance at Quoted Prices in Significant Significant March 31, Active Markets Other Unobservable 2022 for Identical Observable Inputs Items Inputs (Level 3) (Level 1) (Level 2) Assets Deposit held as a certificate of deposit 152 152 — — Total assets $ 152 $ 152 $ — $ — Liabilities Warrant liability $ — — — $ — Contingent earnout liability 342 — — 342 Total liabilities $ 342 $ — $ — $ 342 The following is a reconciliation of the beginning and ending balances for the liabilities measured at fair value on a recurring basis using significant unobservable inputs (Level 3 March 31, 2022 ( Fair value of warrant liability at December 31, 2021 $ 9,558 Decrease in fair value of 2021 Warrants (2,056 ) Reclassification of warrant liability to equity (7,502 ) Fair value of warrant liability at March 31, 2022 $ — Fair value of contingent liability at December 31, 2021 $ 561 Decrease in fair value of contingent liability (219 ) Fair value of contingent liability at March 31, 2022 $ 342 The following table presents the Company's assets measured at fair value on a recurring basis as of December 31, 2021 ( Fair Value Measurements Using Balance at Quoted Prices in Significant Significant December 31, Active Markets Other Unobservable 2021 for Identical Observable Inputs Items Inputs (Level 3) (Level 1) (Level 2) Assets Restricted cash held as a certificate of deposit $ 324 $ 324 $ — $ — Deposit held as a certificate of deposit 151 151 — — Total assets $ 475 $ 475 $ — $ — Liabilities Warrant liability $ 9,558 — — $ 9,558 Contingent earnout liability 561 — — 561 Total liabilities $ 10,119 $ — $ — $ 10,119 The following is a reconciliation of the beginning and ending balances for the liabilities measured at fair value on a recurring basis using significant unobservable inputs (Level 3 December 31, 2021 ( Fair value of warrant liability at December 31, 2020 $ — Fair value of 2021 Warrants issued 14,172 Decrease in fair value of 2021 Warrants (4,614 ) Fair value of warrant liability at December 31, 2021 $ 9,558

Note 5 - Prepaid Expenses and O

Note 5 - Prepaid Expenses and Other Current Assets	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Prepaid Expenses and Other Current Assets [Text Block]	NOTE 5. Prepaid expenses and other current assets consisted of the following (in thousands): March 31, December 31, 2022 2021 Prepaid inventory $ 335 $ 367 Prepaid dues and subscription 93 18 Prepaid insurance 77 138 Prepaid consultant 8 68 Prepaid patents 8 9 Prepaid sales rebates 3 19 Prepaid rent — 14 Other 228 145 Total prepaid expenses and other current assets $ 752 $ 778

Note 6 - Inventory

Note 6 - Inventory	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Inventory Disclosure [Text Block]	NOTE 6. Inventory consisted of the following (in thousands): March 31, December 31, 2022 2021 Raw materials and supplies $ 1,446 $ 1,179 Finished goods 2,861 2,682 Less: Reserve for excess and obsolete inventory (522 ) (641 ) Total inventory, net $ 3,785 $ 3,220

Note 7 - Property and Equipment

Note 7 - Property and Equipment	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Property, Plant and Equipment Disclosure [Text Block]	NOTE 7. Property and equipment consisted of the following (in thousands): March 31, December 31, 2022 2021 Office and laboratory equipment $ 20 $ 20 Furniture and fixtures 157 157 Computer equipment and software 464 464 Production equipment 138 114 Leasehold improvements 79 79 Total property and equipment, at cost 858 834 Less: accumulated depreciation and amortization (671 ) (641 ) Total property and equipment, net $ 187 $ 193 Depreciation and amortization expense was $30 thousand and $9 thousand for the three March 31, 2022 2021,

Note 8 - Goodwill

Note 8 - Goodwill	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Goodwill Disclosure [Text Block]	NOTE 8. Goodwill is accounted for in accordance to ASC 350, Intangibles-Goodwill and Other. not may three March 31, 2022. no March 31, 2022. March 31, 2022 December 31, 2021.

Note 9 - Other Intangible Asset

Note 9 - Other Intangible Assets	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Intangible Assets Disclosure [Text Block]	NOTE 9. Other intangible assets consisted of the following (in thousands): Balance at December 31, 2021 Accumulated Gross Amortization Net Indefinite-lived intangible assets Trade names $ 2,080 $ — $ 2,080 Amortizable intangible assets Customer relationships $ 290 $ (7 ) $ 283 Trade secrets / product formulations 2,890 (53 ) 2,837 Total other intangible assets $ 5,260 $ (60 ) $ 5,200 Balance at March 31, 2022 Accumulated Gross Amortization Net Indefinite-lived intangible assets Trade names $ 2,080 $ — $ 2,080 Amortizable intangible assets Customer relationships $ 290 $ (17 ) $ 273 Trade secrets / product formulations 2,890 (134 ) 2,756 Total other intangible assets $ 5,260 $ (151 ) $ 5,109 Amortization expense was $91 thousand and $0 for the three March 31, 2022 2021, March 31, 2022, 2022 $ 272 2023 363 2024 363 2025 363 2026 363 Thereafter 1,305 Total $ 3,029

Note 10 - Accrued Liabilities

Note 10 - Accrued Liabilities	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Accounts Payable and Accrued Liabilities Disclosure [Text Block]	NOTE 10. Accrued liabilities consisted of the following (in thousands): March 31, December 31, 2022 2021 Contract liabilities (see Note 16) $ 1,914 $ 1,289 Employee payroll and benefits 397 443 Audit services 95 — Other 357 360 Total accrued liabilities $ 2,763 $ 2,092

Note 11 - Line of Credit

Note 11 - Line of Credit	3 Months Ended
	Mar. 31, 2022
Line of Credit [Member]
Notes to Financial Statements
Debt Disclosure [Text Block]	NOTE 11. At the time of the DERMAdoctor Acquisition, DERMAdoctor had a line of credit agreement with Bank Midwest for $500 thousand. There was no balance outstanding on the line of credit at the time of Acquisition Closing. The line of credit was terminated and repaid in full on January 6, 2022. March 31, 2022,

Note 12 - Commitments and Conti

Note 12 - Commitments and Contingencies	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Commitments and Contingencies Disclosure [Text Block]	NOTE 12. Indemnification Agreements As permitted under Delaware law and in accordance with its bylaws, the Company indemnifies its officers and directors for certain events or occurrences while the officer or director is or was serving at the Company’s request in such capacity. The term of the indemnification period is for the officer’s or director’s lifetime. The maximum amount of potential future indemnification is unlimited; however, the Company has a director and officer insurance policy that limits its exposure and may not March 31, 2022. In the normal course of business, the Company provides indemnification of varying scope under its agreements with other entities, typically its clinical research organizations, investigators, clinical sites, suppliers, and others. Pursuant to these agreements, it generally indemnifies, holds harmless, and agrees to reimburse the indemnified parties for losses suffered or incurred by the indemnified parties in connection with the use or testing of its products or product candidates or with any U.S. patent or any copyright or other intellectual property infringement claims by any third not March 31, 2022. Legal Matters As of March 31, 2022, no Leases The Company leases office space for its corporate headquarters located in Emeryville, California. The initial lease term was scheduled to expire on February 28, 2022, January 19, 2022, July 31, 2027. We are also party to a lease for 19,136 square feet of space located in Riverside, Missouri, which we utilize for light manufacturing, storage, distribution of products and administrative functions. The lease commenced on October 1, 2019 December 31, 2024. In calculating the present value of the lease payments, the Company utilized its incremental borrowing rate. The Company has elected to account for each lease component and its associated non-lease components as a single lease component and has allocated all of the contract consideration across lease components only. This will potentially result in the initial and subsequent measurement of the balances of the right-of-use assets and lease liability for leases being greater than if the policy election was not not The components of lease expense for the three March 31, 2022 2021 Lease Costs Three Months Ended March 31, 2022 2021 Operating lease cost $ 134 $ 99 Net lease cost $ 134 $ 99 Other information Operational cash flow used for operating leases $ 111 $ 113 The Company has measured its operating lease liabilities at its incremental borrowing rate over the remaining term for each operating lease. The weighted average remaining lease term and the weighted average discount rate are summarized as follows: Three Months Ended March 31, 2022 2021 Weighted-average remaining lease term (in years) 5.0 1.0 Weighted-average discount rate 5 % 12 % Future lease payments under non-cancelable leases as of March 31, 2022 2022 $ 430 2023 535 2024 549 Thereafter 1,166 Total future minimum lease payments 2,680 Less imputed interest (293 ) Total $ 2,387 Reported as: Operating lease liability $ 465 Operating lease liability- non-current 1,922 Total $ 2,387 Contracts On May 13, 2020, September 4, 2020 February 4, 2021. January 22, 2021( 14,

Note 13 - Warrant Liability

Note 13 - Warrant Liability	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Other Liabilities Disclosure [Text Block]	NOTE 13. 2019 As further described in Note 14, 2019 2019 2019 third 2019. 2019 2019 2019 480, Distinguishing Liabilities from Equity Upon issuance in the third 2019, 2019 2019 2019 In the third 2020, 14, 2019 2019 2019 2019 Assumptions 2019 Domestic Warrants 2019 Foreign Warrants Expected price volatility 178 % 178 % Expected term (in years) 4.57 4.57 Risk-free interest rate 0.25 % 0.27 % Dividend yield 0.00 % 0.00 % Weighted-average fair value of warrant $ 1.18 $ 1.54 There were no 2019 2019 March 31, 2022. In the third 2020, 14, 2019 2019 no 2019 2019 Expected price volatility 186 % Expected term (in years) 4.05 Risk-free interest rate 0.22 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 1.17 The 2019 no 2019 March 31, 2022. November 2021 As further described in Note 14, 2021 fourth 2021. 2021 480, Distinguishing Liabilities from Equity 2021 December 31, 2021 2021 2021 December 31, 2021, January 31, 2022. January 31, 2022, January 31, 2022, November 2021 March 31, 2022. Upon issuance, the fair value of the 2021 November 2, 2021: Expected price volatility 84.9 % Expected term (in years) 6.2 Risk-free interest rate 1.29 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 0.38 As of December 31, 2021, 2021 Expected price volatility 87 % Expected term (in years) 6.0 Risk-free interest rate 1.31 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 0.25

Note 14 - Stockholders' Equity

Note 14 - Stockholders' Equity	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Stockholders' Equity Note Disclosure [Text Block]	NOTE 14. Preferred Stock and 2021 The Company is authorized to issue up to 5,000,000 shares of preferred stock with rights and preferences as may On October 29, 2021, “2021 “2021 2021 November 2, 2021. The 2021 not 713 37,500,000 37,500,000 December 17, 2021 ( January 31, 2022, December 31, 2021 six 6 Each share of the Preferred Stock that we issued in the Private Placement had a purchase price of $1,000 per share and is initially convertible at a conversion price of $0.40 into 2,500 shares of Common Stock, or an aggregate of 37,500,000 2021 no December 31, 2021. not The Company allocated the net proceeds between the Preferred Stock and the 2021 first 2021 13, 2021 In connection with the issuance of the Preferred Stock, the Company recorded a beneficial conversion feature of $0.7 million as a discount to Preferred Stock and an increase to additional paid in capital. The Company fully amortized the discount related to the beneficial conversion feature on the deemed dividend in the consolidated statements of operations and comprehensive loss upon approval of the Share Issuance Proposal in the fourth 2021. The Company incurred total issuance costs of $1.7 million in conjunction with the 2021 December 31, 2021. During the first 2022, March 31, 2022. Common Stock May 2021 In the second 2021, 2021 8 May 14, 2021. second 2021, 2021 Common Stock Warrants 2019 2019 2019 July 2020 In the third 2019, “2019 “2019 2019 February 13, 2025. The Company allocated the proceeds between the common stock and 2019 first 2019 13, 2019 Ladenburg served as the placement agent for the transaction in exchange for a commission representing six August 8, 2024 ( “2019 The Company incurred total issuance costs of $0.5 million in conjunction with the 2019 2019 13, 2019 During the third 2020, 2019 2019 six 2019 During the third 2020, 2019 2019 2019 2019 1 2019 2019 2 “July 2020 100% 2019 2019 The July 2020 nine July 2020 five 2019 2019 July 2020 one not July 2020 July 2020 March 31, 2022. During the third 2020, 2019 13 2019 no TLF Bio Innovation Warrants On January 15, 2021, five The details of all outstanding warrants as of March 31, 2022 Warrants (in thousands) Weighted- Average Exercise Price Outstanding at December 31, 2021 7,082 $ 1.63 Warrants granted 37,500 $ 0.53 Outstanding at March 31, 2022 44,582 $ 0.71

Note 15 - Equity-based Compensa

Note 15 - Equity-based Compensation	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Share-Based Payment Arrangement [Text Block]	NOTE 15. Equity Compensation Plans In October 2007, 2007 “2007 2007 March 15, 2017. 2007 2007 no ten 2007 March 31, 2022. In March 2017, 2017 “2017 June 2, 2017, 2017 not 2007 2017 first January 1, 2018 January 1, 2027 4 2017 January 15, 2021, 2017 March 31, 2022, 2017 Under the terms of the 2017 may not not not ten not five 10% four 2007 2017 Stock Option Summary The following table summarizes information about the Company’s stock options outstanding at March 31, 2022 March 31, 2022: (in thousands, except years and per share data) Options Weighted- Average Exercise Price Weighted- Average Remaining Contractual Life (years) Aggregate Intrinsic Value Outstanding at December 31, 2021 4,449 $ 1.39 7.6 $ 460 Options granted 332 $ 0.30 Options forfeited/cancelled (21 ) $ 10.94 Outstanding at March 31, 2022 4,760 $ 1.27 7.6 $ 356 Vested and expected to vest at March 31, 2022 4,416 $ 1.33 7.5 $ 313 Vested at March 31, 2022 2,218 $ 2.30 5.8 $ — Exercisable at March 31, 2022 2,218 $ 2.30 5.8 $ — The aggregate intrinsic value is calculated as the difference between the exercise price of the underlying stock option awards and the closing market price of the Company’s common stock as quoted on the NYSE American as of March 31, 2022 three March 31, 2022. three March 31, 2022. As of March 31, 2022, Stock Option Awards to Employees and Directors The Company grants options to purchase common stock to its employees and directors at prices equal to or greater than the market value of the stock on the dates the options are granted. The Company has estimated the value of stock option awards as of the date of grant by applying the Black-Scholes option pricing model using the single-option valuation approach. The application of this valuation model involves assumptions that are judgmental and subjective in nature. See Note 2, During the three March 31, 2022 2021, The weighted-average assumptions used in determining the value of options are as follows: Three Months Ended March 31, Assumption 2022 2021 Expected price volatility 160.47 % 164.44 % Expected term (in years) 6.45 6.19 Risk-free interest rate 1.63 % 1.09 % Dividend yield 0.00 % 0.00 % Weighted-average fair value of options granted during the period $ 0.29 $ 1.04 Expected Price Volatility Expected Term Risk-Free Interest Rate Dividend Yield not Forfeitures are estimated at the time of grant and reduce compensation expense ratably over the vesting period. This estimate is adjusted periodically based on the extent to which actual forfeitures differ, or are expected to differ, from the previous estimate. During the three March 31, 2022 2021, not For the three March 31, 2022 2021, Stock-Based Awards to Non-Employees During the three March 31, 2022 2021, not When the Company grants stock options, the stock options are recorded at their fair value on the grant date and recognized over the respective service or vesting period. The fair value of the stock options that are granted is calculated using the Black-Scholes-Merton option pricing model. In addition, during the three March 31, 2022 2021, not For the three March 31, 2022, three March 21, 2021, Summary of Stock-Based Compensation Expense A summary of the stock-based compensation expense included in results of operations for the options and restricted stock awards discussed above is as follows (in thousands): Three Months Ended March 31, 2022 2021 Research and development $ 4 $ 4 Sales and marketing 12 31 General and administrative 168 148 Total stock-based compensation expense $ 184 $ 183

Note 16 - License, Collaboratio

Note 16 - License, Collaboration and Distribution Agreements	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
License, Collaboration, and Distribution Agreements [Text Block]	NOTE 16. Transactions under the Company’s major distribution agreements are recognized upon transfer of control of product sold to its major distribution partners at the amount of consideration that the Company expects to be entitled to. The Company records contract liabilities for the amounts that are estimated to be subject to significant reversal, including allowances for services, discounts, rebate programs, and product returns. The following table presents changes in the Company's contract assets and liabilities for the three March 31, 2022 ( Balance at December 31, 2021 Additions Deductions Balance at the end of the Period Contract liabilities: deferred revenue $ 2 $ 69 $ (2 ) $ 69 Contract liabilities: accrued liabilities (includes contract assets) 1,270 842 (201 ) 1,911 Total $ 1,272 $ 911 $ (203 ) $ 1,980 For the three March 31, 2022 2021, Three Months Ended March 31, 2022 2021 Revenue recognized in the period from: Amounts included in contract liabilities at the beginning of the period: Performance obligations satisfied $ 201 $ 575 New activities in the period: Performance obligations satisfied 2,428 1,232 $ 2,629 $ 1,807 Avenova Spray Pharmacy Distribution Agreements and Specialty Pharmacies Avenova Spray is made available in local pharmacies and major pharmacy retail chains under nationwide distribution agreements with McKesson Corporation, Cardinal Health and AmerisourceBergen. We have also entered into direct agreements with preferred pharmacy networks as part of our Partner Pharmacy Program. The Company incurred net sales loss of $199 thousand during the three March 31, 2022, three March 31, 2021 three March 31, 2022, Under the prescription Avenova Spray product distribution arrangements, the Company had a contract liability balance of $1.3 million and $0.9 million as of March 31, 2022 December 31, 2021, March 31, 2022 December 31, 2021, 5, Over-the-Counter Sales of Avenova Spray Avenova Spray was launched online on June 1, 2019 February 2021. three March 31, 2022 2021, DERMAdoctor DERMAdoctor products are available through wholesale distribution relationships with third March 31, 2022, December 31, 2021,

Note 17 - Employee Benefit Plan

Note 17 - Employee Benefit Plan	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Retirement Benefits [Text Block]	NOTE 17. The Company has a 401 not December 31, 2021. 401 January 1, 2022, first

Note 18 - Related Party Transac

Note 18 - Related Party Transactions	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Related Party Transactions Disclosure [Text Block]	NOTE 18. Related Party Revenue The following table summarizes information about the Company’s related party revenue and cost of goods sold during the three March 31, 2022 2021, Three Months Ended March 31, 2022 2021 Related party revenue: NeutroPhase $ 148 $ — Total related party revenue $ 148 $ — Cost of goods sold: NeutroPhase $ (134 ) $ — Total related party expenses $ (134 ) $ — Related party accounts receivable was $0.1 million as of both March 31, 2022 December 31, 2021.

Note 19 - Paycheck Protection P

Note 19 - Paycheck Protection Program	3 Months Ended
	Mar. 31, 2022
COVID 19 Member [Member]
Notes to Financial Statements
Unusual or Infrequent Items, or Both, Disclosure [Text Block]	NOTE 19. On May 6, 2020, March 27, 2020. 2020, September 5, 2020. 1.00% two 2021. no 24 Since the Company determined that there was reasonable assurance that it would meet the conditions for forgiveness of the full loan amount, the Company accounted for the forgivable PPP Loan as a government income grant that we earned through the Company’s compliance with the loan forgiveness criteria. A deferred income liability was recognized upon receipt of the forgivable loan proceeds. The deferred income liability was recognized as other income as Qualifying Expenses were incurred. For the year ended December 31, 2020, No March 31, 2022. The Company received notice, dated May 24, 2021,

Note 20 - Segment Reporting

Note 20 - Segment Reporting	3 Months Ended
	Mar. 31, 2022
Notes to Financial Statements
Segment Reporting Disclosure [Text Block]	NOTE 20. The Company’s chief operating decision maker (“CODM”), who is the Company’s Chief Executive Officer, allocates resources and assesses performance based on financial information of the Company. The CODM reviews financial information presented for each reportable segment for purposes of making operating decisions and assessing financial performance. Prior to the DERMAdoctor Acquisition in November 2021 ( 3, 1 2 Select financial information for each segment is as follows (in thousands): Three Months Ended March 31, 2022 2021 Net sales Optical & Wound Care $ 1,738 $ 1,807 Skincare 891 — Consolidated $ 2,629 $ 1,807 Operating loss Optical & Wound Care $ (2,039 ) $ (1,520 ) Skincare (343 ) — Consolidated $ (2,382 ) $ (1,520 ) The Company’s reportable segments are strategic business units that offer different products. Each segment is managed independently because they require different operations and markets to distinct classes of customers. Operating costs included in one may not may

Significant Accounting Policies

Significant Accounting Policies (Policies)	3 Months Ended
	Mar. 31, 2022
Accounting Policies [Abstract]
Basis of Accounting, Policy [Policy Text Block]	Basis of Presentation The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”) and are expressed in U.S. dollars. In management’s opinion, the condensed consolidated financial statements include all normal and recurring adjustments that are considered necessary for the fair presentation of the Company’s financial position and operating results.
Use of Estimates, Policy [Policy Text Block]	Use of Estimates The preparation of financial statements in accordance with U.S. GAAP requires management to make estimates and assumptions that affect the amounts reported in the unaudited condensed consolidated financial statements and accompanying notes. These estimates include contract liabilities related to product sales, useful lives for property and equipment and related depreciation calculations, assumptions for valuing options and warrants, the fair value of contingent consideration, intangible assets, goodwill, stock-based compensation, income taxes and other contingencies as of March 31, 2022. These estimates are based on management’s best estimates and judgment. Actual results may
Cash and Cash Equivalents, Policy [Policy Text Block]	Cash, Cash Equivalents, and Restricted Cash The Company considers all highly-liquid instruments with a stated maturity of three March 31, 2022 December 31, 2021, The following table provides a reconciliation of the cash, cash equivalents, and restricted cash reported in the condensed consolidated balance sheets that sum to the total of the same reported in the condensed consolidated statements of cash flows (in thousands): March 31, December 31, 2022 2021 Cash and cash equivalents $ 5,641 $ 7,504 Restricted cash included in other assets 152 475 Total cash, cash equivalents, and restricted cash in the condensed consolidated statements of cash flows $ 5,793 $ 7,979 The restricted cash amount included in other assets on the condensed consolidated balance sheets represents amounts held as certificates of deposit for long-term financing and lease arrangements as contractually required by our financial institution and landlord.
Concentration Risk, Credit Risk, Policy [Policy Text Block]	Concentrations of Credit Risk and Major Partners Financial instruments that potentially subject us to significant concentrations of credit risk consist primarily of cash, cash equivalents and restricted cash. The Company maintains deposits of cash, cash equivalents and restricted cash with a highly-rated, major financial institution in the United States. Deposits in this bank may not During the three March 31, 2022 2021, three March 31, 2022, During the three March 31, 2022 2021, Three Months Ended March 31, 2022 2021 Avenova Spray $ 1,426 $ 1,575 DERMAdoctor 891 — NeutroPhase 148 — Other products 158 226 Total product revenue, net 2,623 1,801 Other revenue, net 6 6 Total sales, net $ 2,629 $ 1,807 During the three March 31, 2022 2021, No 10% three March 31, 2022 2021. three March 31, 2022 no three March 31, 2021. As of March 31, 2022 December 31, 2021, 10% March 31, December 31, Major distribution partner 2022 2021 Major U.S. Retailer 35 % 33 % Avenova Spray Pharmacy Distributor B 14 % 11 % Avenova Spray Pharmacy Distributor A 13 % 13 % The Company relies on seven not third may may not may 19
Fair Value of Financial Instruments, Policy [Policy Text Block]	Fair Value of Financial Assets and Liabilities The Company’s financial instruments include cash and cash equivalents, restricted cash, accounts receivable, accounts payable, accrued liabilities, and contingent consideration. The Company’s cash and cash equivalents, accounts receivable, accounts payable, and accrued liabilities are carried at cost, which management believes approximates fair value due to the short-term nature of these instruments. The Company follows Accounting Standards Codification (“ASC”) 820, Fair Value Measurements and Disclosures three may Level 1 Level 2 Level 3 Categorization within the valuation hierarchy is based upon the lowest level of input that is significant to the fair value measurement.
Receivables, Trade and Other Accounts Receivable, Allowance for Doubtful Accounts, Policy [Policy Text Block]	Allowance for Doubtful Accounts The Company charges bad debt expense and records an allowance for doubtful accounts when management believes it to be unlikely that specific invoices will be collected. Management identifies amounts due that are in dispute and believes are unlikely to be collected. Management recorded no reserve for accounts receivable at March 31, 2022 December 31, 2021.
Inventory, Policy [Policy Text Block]	Inventory Inventory is comprised of ( 1 2 3 first first March 31, 2022 December 31, 2021,
Property, Plant and Equipment, Policy [Policy Text Block]	Property and Equipment, net Property and equipment are stated at cost, less accumulated depreciation and amortization. Depreciation is calculated using the straight-line method over the estimated useful lives of the related assets of five seven three five five seven The costs of normal maintenance, repairs, and minor replacements are expensed as incurred.
Business Combinations Policy [Policy Text Block]	Business Combinations We account for 805, Business Combinations The determination of estimated fair value requires us to make significant estimates and assumptions. These fair value determinations require judgment and involve the use of significant estimates and assumptions, including assumptions with respect to future cash inflows and outflows, discount rates, and asset lives, among other items. As a result, we may one Transaction costs associated with business combinations are expensed as they are incurred.
Goodwill and Intangible Assets, Policy [Policy Text Block]	Goodwill and Intangible Assets Goodwill represents the excess of the consideration transferred over the estimated fair value of assets acquired and liabilities assumed in a business combination. Intangible assets are measured at their respective fair values as of the acquisition date and may may one not March 31, 2022 December 31, 2021. Intangible Asset Fair Value (in thousands) Useful Life (in years) Amortization Method Customer relationships $ 290 7 Straight line Trade secrets / product formulations 2,890 9 Straight line Trade names 2,080 Indefinite N/A Goodwill 4,528 Indefinite N/A $ 9,788
Valuation of Contingent Consideration from Business Combination Policy [Policy Text Block]	Valuation of Contingent Consideration Resulting from a Business Combination In connection with certain acquisitions, we may Increases or decreases in fair value of the contingent consideration liabilities can result from updates to assumptions such as the expected timing or probability of achieving the specified milestones. Significant judgment is employed in determining these assumptions as of the acquisition date and for each subsequent period. Updates to assumptions could have a significant impact on our results of operations in any given period. Actual results may
Impairment or Disposal of Long-Lived Assets, Including Intangible Assets, Policy [Policy Text Block]	Impairment of Long-Lived Assets The Company accounts for long-lived assets, other than goodwill and intangible assets, and operating lease right-of-use assets in accordance with ASC 360, Property, Plant and Equipment may may not no not no March 31, 2022 December 31, 2021.
Lessee, Leases [Policy Text Block]	Leases At the inception of an arrangement, the Company determines whether the arrangement is or contains a lease based on the unique facts and circumstances present. Operating lease liabilities and their corresponding right-of-use assets are recorded based on the present value of lease payments over the expected lease term. The interest rate implicit in lease contracts is typically not may The Company has elected to combine lease and non-lease components as a single component for all leases in which it is a lessee or a lessor. The lease expense is recognized over the expected term on a straight-line basis. Operating leases are recognized on the balance sheet as right-of-use assets, operating lease liabilities current and operating lease liabilities non-current.
Comprehensive Income, Policy [Policy Text Block]	Comprehensive Income (Loss) ASC 220, Comprehensive Income,
Revenue from Contract with Customer [Policy Text Block]	Revenue Recognition Revenue is recognized from sale of goods in accordance with ASC 606, Revenue from Contracts with Customers 606” 606, 606, five 606: i. identify the contract(s) with a customer; ii. identify the performance obligations in the contract; iii. determine the transaction price; iv. allocate the transaction price to the performance obligations in the contract; and v. recognize revenue when (or as) the entity satisfies performance obligations. Revenue is generated through the Company’s webstores, Avenova.com and DERMAdoctor.com, for Avenova Spray and DERMAdoctor direct to consumer sales which are recognized upon fulfillment, which generally occurs upon delivery of the related products to a third Revenue generated through Amazon.com and Walmart.com third The Company also generates Avenova Spray revenue through major pharmacy distribution partners. Product supply of Avenova Spray is the only performance obligation contained in these arrangements, and the Company recognizes product revenue upon transfer of control to its major distribution partners at the amount of consideration that the Company expects to be entitled to, generally upon delivery to the distributor on a “sell-in” basis. Upon recognition of product sales, contract liabilities are recorded for invoiced amounts that are subject to significant reversal, including product revenue allowances for cash consideration paid to customers for services, discounts, rebate programs, and product returns. The Company derives its rate of return from historical data and updates its return rate assumption quarterly. Payment for product supply is typically due 30 days after control transfers to the distributor. Revenue generated through the Company’s partner pharmacies is recognized when control of the product transfers to the end customer. Revenue for product sales to other retailers, such as Costco and CVS, is generally recognized upon transfer of control to the retailer, which generally occurs upon delivery of the products to a third
Cost of Goods Sold, Policy [Policy Text Block]	Cost of Goods Sold Cost of goods sold includes third
Research and Development Expense, Policy [Policy Text Block]	Research and Development Costs The Company charges research and development costs to expense as incurred. These costs include all costs associated with research, development and regulatory activities, including submissions to the Food and Drug Administration (the “FDA”).
Patent Costs Policy [Policy Text Block]	Patent Costs Patent costs, including legal expenses, are expensed in the period in which they are incurred. Patent expenses are included in general and administrative expenses in the consolidated statements of operations and comprehensive loss.
Advertising Cost [Policy Text Block]	Advertising Costs Advertising costs are expensed in the period in which the costs are incurred. Advertising expenses were $0.6 million and $0.7 million for the three March 31, 2022 2021,
Share-Based Payment Arrangement [Policy Text Block]	Stock-Based Compensation The Company’s stock-based compensation includes grants of stock options and restricted stock units (“RSUs”) to employees, consultants and non-employee directors. The expense associated with these grants is recognized in the Company’s consolidated statements of stockholders’ equity based on their fair values as they are earned under the applicable vesting terms. For stock options granted, the fair value of the stock options is estimated using a Black-Scholes option pricing model. See Note 15,
Income Tax, Policy [Policy Text Block]	Income Taxes The Company accounts for income taxes under the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment date. A valuation allowance is recognized if it is more likely than not not
Warrant Liabilities [Policy Text Block]	Common Stock Warrant Liabilities The Company accounts for common stock purchase warrants issued in connection with its equity offerings in accordance with the provisions of ASC 480, Distinguishing Liabilities from Equity 815, Derivatives and Hedging The Company accounts for common stock purchase warrants issued in connection with share-based compensation arrangements in accordance with the provisions of ASC 718, Stock Compensation, 480, Distinguishing Liabilities from Equity The Company classifies as equity any contracts that (i) require physical settlement or net-share settlement or (ii) give the Company a choice of net-cash settlement or settlement in its own shares (physical settlement or net-share settlement). The Company classifies as assets or liabilities any contracts that (i) require net-cash settlement (including a requirement to net-cash settle the contract if an event occurs and if that event is outside the control of the Company), (ii) give the counterparty a choice of net-cash settlement or settlement in shares (physical settlement or net-share settlement) or (iii) do not 718, Stock Compensation, For warrants that are classified as liabilities, the Company records the fair value of the warrants at each balance sheet date and records changes in the estimated fair value as a non-cash gain or loss in the consolidated statements of operations and comprehensive loss. The fair values of these warrants are determined using the Black-Scholes option pricing model, the Binomial Lattice (“Lattice”) valuation model, or the Monte Carlo simulation model where deemed appropriate. These values are subject to a significant degree of management’s judgment.
Earnings Per Share, Policy [Policy Text Block]	Net Loss per Share The Company computes net loss per share by presenting both basic and diluted earnings (loss) per share (“EPS”). Basic EPS is computed by dividing net loss available to common stockholders by the weighted average number of common shares outstanding during the period. Diluted EPS gives effect to all dilutive potential common shares outstanding during the period, including stock options and warrants, using the treasury stock method. In computing diluted EPS, the average stock price for the period is used to determine the number of shares assumed to be purchased from the exercise of stock options or warrants. Potentially dilutive common share equivalents are excluded from the diluted EPS computation in net loss periods because their effect would be anti-dilutive. For the year ended December 31, 2021, not The following table sets forth the calculation of basic EPS and diluted EPS (in thousands, except per share amounts): Three Months Ended March 31, Numerator 2022 2021 Net loss $ (111 ) $ (1,518 ) Denominator Weighted average shares of common stock outstanding, basic and diluted 50,088 41,782 Net loss per share attributable to common stockholders, basic and diluted $ 0.00 $ (0.04 ) The following outstanding stock options and stock warrants were excluded from the diluted EPS computation as their effect would have been anti-dilutive (in thousands): Three Months Ended March 31, 2022 2021 Stock options 4,416 3,138 Stock warrants 44,582 7,082 48,998 10,220
New Accounting Pronouncements, Policy [Policy Text Block]	Recent Accounting Pronouncements For information regarding recent accounting pronouncements that could affect our business, results of operations, financial condition, and liquidity, see Note 2, 10 December 31, 2021, March 29, 2022.

Note 2 - Summary of Significa_2

Note 2 - Summary of Significant Accounting Policies (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Table Text Block]	March 31, December 31, 2022 2021 Cash and cash equivalents $ 5,641 $ 7,504 Restricted cash included in other assets 152 475 Total cash, cash equivalents, and restricted cash in the condensed consolidated statements of cash flows $ 5,793 $ 7,979
Schedules of Concentration of Risk, by Product [Table Text Block]	Three Months Ended March 31, 2022 2021 Avenova Spray $ 1,426 $ 1,575 DERMAdoctor 891 — NeutroPhase 148 — Other products 158 226 Total product revenue, net 2,623 1,801 Other revenue, net 6 6 Total sales, net $ 2,629 $ 1,807
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]	March 31, December 31, Major distribution partner 2022 2021 Major U.S. Retailer 35 % 33 % Avenova Spray Pharmacy Distributor B 14 % 11 % Avenova Spray Pharmacy Distributor A 13 % 13 %
Schedule of Intangible Assets and Goodwill [Table Text Block]	Intangible Asset Fair Value (in thousands) Useful Life (in years) Amortization Method Customer relationships $ 290 7 Straight line Trade secrets / product formulations 2,890 9 Straight line Trade names 2,080 Indefinite N/A Goodwill 4,528 Indefinite N/A $ 9,788
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]	Three Months Ended March 31, Numerator 2022 2021 Net loss $ (111 ) $ (1,518 ) Denominator Weighted average shares of common stock outstanding, basic and diluted 50,088 41,782 Net loss per share attributable to common stockholders, basic and diluted $ 0.00 $ (0.04 )
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]	Three Months Ended March 31, 2022 2021 Stock options 4,416 3,138 Stock warrants 44,582 7,082 48,998 10,220

Note 3 - Business Combination (

Note 3 - Business Combination (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]	Fair Value Tangible net assets and liabilities: Cash and cash equivalents $ 12 Accounts receivable, net of allowance for doubtful accounts 1,015 Inventory, net of allowance 2,369 Prepaid expenses and other current assets 150 Property and equipment, net 62 Other intangible assets 54 Accounts payable (200 ) Accrued liabilities (683 ) Total net assets 2,779 Intangible Assets: Customer relationships 290 Trade secrets / product formulations 2,890 Trade names 2,080 Total intangible assets 5,260 Net assets acquired 8,039 Purchased consideration 12,561 Goodwill $ 4,528
Finite-Lived and Indefinite-Lived Intangible Assets Acquired as Part of Business Combination [Table Text Block]	Intangible Asset Fair Value Useful Life (in years) Amortization Method Customer relationships $ 290 7 Straight line Trade secrets / product formulations 2,890 9 Straight line Trade names 2,080 Indefinite N/A Goodwill 4,528 Indefinite N/A $ 9,788

Note 4 - Fair Value Measureme_2

Note 4 - Fair Value Measurements (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Fair Value, Assets Measured on Recurring Basis [Table Text Block]	Fair Value Measurements Using Balance at Quoted Prices in Significant Significant March 31, Active Markets Other Unobservable 2022 for Identical Observable Inputs Items Inputs (Level 3) (Level 1) (Level 2) Assets Deposit held as a certificate of deposit 152 152 — — Total assets $ 152 $ 152 $ — $ — Liabilities Warrant liability $ — — — $ — Contingent earnout liability 342 — — 342 Total liabilities $ 342 $ — $ — $ 342 Fair Value Measurements Using Balance at Quoted Prices in Significant Significant December 31, Active Markets Other Unobservable 2021 for Identical Observable Inputs Items Inputs (Level 3) (Level 1) (Level 2) Assets Restricted cash held as a certificate of deposit $ 324 $ 324 $ — $ — Deposit held as a certificate of deposit 151 151 — — Total assets $ 475 $ 475 $ — $ — Liabilities Warrant liability $ 9,558 — — $ 9,558 Contingent earnout liability 561 — — 561 Total liabilities $ 10,119 $ — $ — $ 10,119
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]	Fair value of warrant liability at December 31, 2021 $ 9,558 Decrease in fair value of 2021 Warrants (2,056 ) Reclassification of warrant liability to equity (7,502 ) Fair value of warrant liability at March 31, 2022 $ — Fair value of contingent liability at December 31, 2021 $ 561 Decrease in fair value of contingent liability (219 ) Fair value of contingent liability at March 31, 2022 $ 342 Fair value of warrant liability at December 31, 2020 $ — Fair value of 2021 Warrants issued 14,172 Decrease in fair value of 2021 Warrants (4,614 ) Fair value of warrant liability at December 31, 2021 $ 9,558

Note 5 - Prepaid Expenses and_2

Note 5 - Prepaid Expenses and Other Current Assets (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]	March 31, December 31, 2022 2021 Prepaid inventory $ 335 $ 367 Prepaid dues and subscription 93 18 Prepaid insurance 77 138 Prepaid consultant 8 68 Prepaid patents 8 9 Prepaid sales rebates 3 19 Prepaid rent — 14 Other 228 145 Total prepaid expenses and other current assets $ 752 $ 778

Note 6 - Inventory (Tables)

Note 6 - Inventory (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Inventory, Current [Table Text Block]	March 31, December 31, 2022 2021 Raw materials and supplies $ 1,446 $ 1,179 Finished goods 2,861 2,682 Less: Reserve for excess and obsolete inventory (522 ) (641 ) Total inventory, net $ 3,785 $ 3,220

Note 7 - Property and Equipme_2

Note 7 - Property and Equipment (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Property, Plant and Equipment [Table Text Block]	March 31, December 31, 2022 2021 Office and laboratory equipment $ 20 $ 20 Furniture and fixtures 157 157 Computer equipment and software 464 464 Production equipment 138 114 Leasehold improvements 79 79 Total property and equipment, at cost 858 834 Less: accumulated depreciation and amortization (671 ) (641 ) Total property and equipment, net $ 187 $ 193

Note 9 - Other Intangible Ass_2

Note 9 - Other Intangible Assets (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Finite-Lived Intangible Assets [Table Text Block]	Balance at December 31, 2021 Accumulated Gross Amortization Net Indefinite-lived intangible assets Trade names $ 2,080 $ — $ 2,080 Amortizable intangible assets Customer relationships $ 290 $ (7 ) $ 283 Trade secrets / product formulations 2,890 (53 ) 2,837 Total other intangible assets $ 5,260 $ (60 ) $ 5,200 Balance at March 31, 2022 Accumulated Gross Amortization Net Indefinite-lived intangible assets Trade names $ 2,080 $ — $ 2,080 Amortizable intangible assets Customer relationships $ 290 $ (17 ) $ 273 Trade secrets / product formulations 2,890 (134 ) 2,756 Total other intangible assets $ 5,260 $ (151 ) $ 5,109
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]	2022 $ 272 2023 363 2024 363 2025 363 2026 363 Thereafter 1,305 Total $ 3,029

Note 10 - Accrued Liabilities (

Note 10 - Accrued Liabilities (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Accrued Liabilities [Table Text Block]	March 31, December 31, 2022 2021 Contract liabilities (see Note 16) $ 1,914 $ 1,289 Employee payroll and benefits 397 443 Audit services 95 — Other 357 360 Total accrued liabilities $ 2,763 $ 2,092

Note 12 - Commitments and Con_2

Note 12 - Commitments and Contingencies (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Lease, Cost [Table Text Block]	Lease Costs Three Months Ended March 31, 2022 2021 Operating lease cost $ 134 $ 99 Net lease cost $ 134 $ 99 Other information Operational cash flow used for operating leases $ 111 $ 113 Three Months Ended March 31, 2022 2021 Weighted-average remaining lease term (in years) 5.0 1.0 Weighted-average discount rate 5 % 12 %
Lessee, Operating Lease, Liability, Maturity [Table Text Block]	2022 $ 430 2023 535 2024 549 Thereafter 1,166 Total future minimum lease payments 2,680 Less imputed interest (293 ) Total $ 2,387 Reported as: Operating lease liability $ 465 Operating lease liability- non-current 1,922 Total $ 2,387

Note 13 - Warrant Liability (Ta

Note 13 - Warrant Liability (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Derivative Instruments [Table Text Block]	Assumptions 2019 Domestic Warrants 2019 Foreign Warrants Expected price volatility 178 % 178 % Expected term (in years) 4.57 4.57 Risk-free interest rate 0.25 % 0.27 % Dividend yield 0.00 % 0.00 % Weighted-average fair value of warrant $ 1.18 $ 1.54 Expected price volatility 186 % Expected term (in years) 4.05 Risk-free interest rate 0.22 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 1.17 Expected price volatility 84.9 % Expected term (in years) 6.2 Risk-free interest rate 1.29 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 0.38 Expected price volatility 87 % Expected term (in years) 6.0 Risk-free interest rate 1.31 % Dividend yield 0.00 % Weighted-average fair value of warrants $ 0.25

Note 14 - Stockholders' Equity

Note 14 - Stockholders' Equity (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]	Warrants (in thousands) Weighted- Average Exercise Price Outstanding at December 31, 2021 7,082 $ 1.63 Warrants granted 37,500 $ 0.53 Outstanding at March 31, 2022 44,582 $ 0.71

Note 15 - Equity-based Compen_2

Note 15 - Equity-based Compensation (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Share-Based Payment Arrangement, Option, Activity [Table Text Block]	(in thousands, except years and per share data) Options Weighted- Average Exercise Price Weighted- Average Remaining Contractual Life (years) Aggregate Intrinsic Value Outstanding at December 31, 2021 4,449 $ 1.39 7.6 $ 460 Options granted 332 $ 0.30 Options forfeited/cancelled (21 ) $ 10.94 Outstanding at March 31, 2022 4,760 $ 1.27 7.6 $ 356 Vested and expected to vest at March 31, 2022 4,416 $ 1.33 7.5 $ 313 Vested at March 31, 2022 2,218 $ 2.30 5.8 $ — Exercisable at March 31, 2022 2,218 $ 2.30 5.8 $ —
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]	Three Months Ended March 31, 2022 2021 Research and development $ 4 $ 4 Sales and marketing 12 31 General and administrative 168 148 Total stock-based compensation expense $ 184 $ 183
Employees and Directors [Member]
Notes Tables
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]	Three Months Ended March 31, Assumption 2022 2021 Expected price volatility 160.47 % 164.44 % Expected term (in years) 6.45 6.19 Risk-free interest rate 1.63 % 1.09 % Dividend yield 0.00 % 0.00 % Weighted-average fair value of options granted during the period $ 0.29 $ 1.04

Note 16 - License, Collaborat_2

Note 16 - License, Collaboration and Distribution Agreements (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]	Balance at December 31, 2021 Additions Deductions Balance at the end of the Period Contract liabilities: deferred revenue $ 2 $ 69 $ (2 ) $ 69 Contract liabilities: accrued liabilities (includes contract assets) 1,270 842 (201 ) 1,911 Total $ 1,272 $ 911 $ (203 ) $ 1,980
Disaggregation of Revenue [Table Text Block]	Three Months Ended March 31, 2022 2021 Revenue recognized in the period from: Amounts included in contract liabilities at the beginning of the period: Performance obligations satisfied $ 201 $ 575 New activities in the period: Performance obligations satisfied 2,428 1,232 $ 2,629 $ 1,807

Note 18 - Related Party Trans_2

Note 18 - Related Party Transactions (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Related Party Transactions [Table Text Block]	Three Months Ended March 31, 2022 2021 Related party revenue: NeutroPhase $ 148 $ — Total related party revenue $ 148 $ — Cost of goods sold: NeutroPhase $ (134 ) $ — Total related party expenses $ (134 ) $ —

Note 20 - Segment Reporting (Ta

Note 20 - Segment Reporting (Tables)	3 Months Ended
	Mar. 31, 2022
Notes Tables
Schedule of Segment Reporting Information, by Segment [Table Text Block]	Three Months Ended March 31, 2022 2021 Net sales Optical & Wound Care $ 1,738 $ 1,807 Skincare 891 — Consolidated $ 2,629 $ 1,807 Operating loss Optical & Wound Care $ (2,039 ) $ (1,520 ) Skincare (343 ) — Consolidated $ (2,382 ) $ (1,520 )

Note 1 - Organization (Details

Note 1 - Organization (Details Textual)	3 Months Ended
	Mar. 31, 2022
Number of Reportable Segments	2

Note 2 - Summary of Significa_3

Note 2 - Summary of Significant Accounting Policies (Details Textual) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Accounts Receivable, Allowance for Credit Loss, Ending Balance	$ 0		$ 0
Inventory Valuation Reserves	522		641
Goodwill and Intangible Asset Impairment, Total	$ 0		$ 0
Payment for Product Supply Period (Day)	30 days
Advertising Expense	$ 600	$ 700
Equipment [Member] | Minimum [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Equipment [Member] | Maximum [Member]
Property, Plant and Equipment, Useful Life (Year)	7 years
Computer Equipment and Software [Member] | Minimum [Member]
Property, Plant and Equipment, Useful Life (Year)	3 years
Computer Equipment and Software [Member] | Maximum [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Furniture and Fixtures [Member] | Minimum [Member]
Property, Plant and Equipment, Useful Life (Year)	5 years
Furniture and Fixtures [Member] | Maximum [Member]
Property, Plant and Equipment, Useful Life (Year)	7 years
Revenue from Contract with Customer Benchmark [Member] | Distributor Concentration Risk [Member] | Avenova Spray [Member]
Concentration Risk, Percentage	77.00%	65.00%
Revenue from Contract with Customer Benchmark [Member] | Distributor Concentration Risk [Member] | DERMAdoctor [Member]
Concentration Risk, Percentage	25.00%

Note 2 - Summary of Significa_4

Note 2 - Summary of Significant Accounting Policies - Components of Cash, Cash Equivalents, and Restricted Cash (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021	Mar. 31, 2021	Dec. 31, 2020
Cash and cash equivalents	$ 5,641	$ 7,504
Restricted cash included in other assets	152	475
Total cash, cash equivalents, and restricted cash in the condensed consolidated statements of cash flows	$ 5,793	$ 7,979	$ 10,983	$ 12,427

Note 2 - Summary of Significa_5

Note 2 - Summary of Significant Accounting Policies - Disaggregation of Revenue (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Total sales, net	$ 2,629	$ 1,807
Avenova Spray [Member]
Total sales, net	1,426	1,575
DERMAdoctor [Member]
Total sales, net	891	0
NeutroPhase [Member]
Total sales, net	148	0
Other Products [member]
Total sales, net	158	226
Total Product Revenue [Member]
Total sales, net	2,623	1,801
Product and Service, Other [Member]
Total sales, net	$ 6	$ 6

Note 2 - Summary of Significa_6

Note 2 - Summary of Significant Accounting Policies - Revenues and Accounts Receivable From Major Distribution Partners and Customers (Details) - Customer Concentration Risk [Member] - Accounts Receivable [Member]	3 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Major US Retailer [Member]
Distribution or collaboration partners	35.00%
Distributor B [Member]
Distribution or collaboration partners		11.00%
Distributor A [Member]
Distribution or collaboration partners	13.00%	13.00%

Note 2 - Summary of Significa_7

Note 2 - Summary of Significant Accounting Policies - Goodwill and Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Nov. 05, 2021
Intangible Assets, Including Goodwill, Fair Value Disclosure	$ 9,788	$ 9,788
Finite-Lived Intangible Assets [Member] | Customer Relationships [Member]
Customer relationships	$ 290
Useful life (Year)	7 years
Finite-Lived Intangible Assets [Member] | Trade Secrets [Member]
Customer relationships	$ 2,890
Useful life (Year)	9 years
Indefinite-Lived Intangible Assets [Member] | Trade Names [Member]
Trade names	$ 2,080
Goodwill [Member]
Goodwill	$ 4,528

Note 2 - Summary of Significa_8

Note 2 - Summary of Significant Accounting Policies - Calculation of Basic and Diluted EPS (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Net loss	$ (111)	$ (1,518)
Weighted-average shares of common stock used in computing net loss per share attributable to common stockholders (basic and diluted) (in shares)	50,088	41,782
Net loss per share attributable to common stockholders (basic and diluted) (in dollars per share)	$ 0	$ (0.04)

Note 2 - Summary of Significa_9

Note 2 - Summary of Significant Accounting Policies - Outstanding Stock Options and Stock Warrants Excluded From the Diluted Net Loss Per Share Computation (Details) - shares shares in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Anti-dilutive securities (in shares)	48,998	10,220
Share-Based Payment Arrangement, Option [Member]
Anti-dilutive securities (in shares)	4,416	3,138
Warrant [Member]
Anti-dilutive securities (in shares)	44,582	7,082

Note 3 - Business Combination_2

Note 3 - Business Combination (Details Textual) $ in Millions	Nov. 05, 2021USD ($)	Mar. 31, 2022	Dec. 31, 2021USD ($)
Number of Operating Segments		2
General and Administrative Expense [Member]
Business Combination, Acquisition Related Costs			$ 1.2
DERMAdoctor [Member]
Payments to Acquire Businesses, Gross	$ 12
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, High	$ 3

Note 3 - Business Combination -

Note 3 - Business Combination - Purchase Price Allocation of Estimated Fair Values of Identifiable Assets Acquired and Liabilities Assumed (Details) - USD ($) $ in Thousands	Nov. 05, 2021	Mar. 31, 2022	Dec. 31, 2021
Goodwill		$ 4,528	$ 4,528
DERMAdoctor [Member]
Cash and cash equivalents	$ 12
Accounts receivable, net of allowance for doubtful accounts	1,015
Inventory, net of allowance	2,369
Prepaid expenses and other current assets	150
Property and equipment, net	62
Other intangible assets	54
Accounts payable	(200)
Accrued liabilities	(683)
Total net assets	2,779
Intangible assets	5,260
Net assets acquired	8,039
Purchased consideration	12,561
Goodwill	4,528
DERMAdoctor [Member] | Customer Relationships [Member]
Intangible assets	290
DERMAdoctor [Member] | Trade Secrets [Member]
Intangible assets	2,890
DERMAdoctor [Member] | Trade Names [Member]
Intangible assets	$ 2,080

Note 3 - Business Combination_3

Note 3 - Business Combination - Fair Value of Identifiable Intangible Assets Acquired (Details) - USD ($) $ in Thousands	Nov. 05, 2021	Mar. 31, 2022
Intangible Assets, Including Goodwill, Fair Value Disclosure	$ 9,788	$ 9,788
Finite-Lived Intangible Assets [Member] | Customer Relationships [Member]
Customer relationships		$ 290
Useful life (Year)		7 years
Finite-Lived Intangible Assets [Member] | Customer Relationships [Member] | DERMAdoctor [Member]
Customer relationships	$ 290
Useful life (Year)	7 years
Finite-Lived Intangible Assets [Member] | Trade Secrets [Member]
Customer relationships		$ 2,890
Useful life (Year)		9 years
Finite-Lived Intangible Assets [Member] | Trade Secrets [Member] | DERMAdoctor [Member]
Customer relationships	$ 2,890
Useful life (Year)	9 years
Indefinite-Lived Intangible Assets [Member] | Trade Names [Member]
Trade names		$ 2,080
Indefinite-Lived Intangible Assets [Member] | DERMAdoctor [Member] | Trade Names [Member]
Trade names	$ 2,080
Goodwill [Member]
Goodwill		$ 4,528
Goodwill [Member] | DERMAdoctor [Member]
Goodwill	$ 4,528

Note 4 - Fair Value Measureme_3

Note 4 - Fair Value Measurements - Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Contingent earnout liability	$ 342	$ 561
Fair Value, Recurring [Member]
Deposit held as a certificate of deposit	152	151
Total assets	152	475
Contingent earnout liability	342	561
Total liabilities	342	10,119
Restricted cash held as a certificate of deposit		324
Warrant liability		9,558
Fair Value, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Deposit held as a certificate of deposit	152	151
Total assets	152	475
Contingent earnout liability	0	0
Total liabilities	0	0
Restricted cash held as a certificate of deposit		324
Warrant liability		0
Fair Value, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Deposit held as a certificate of deposit	0	0
Total assets	0	0
Contingent earnout liability	0	0
Total liabilities	0	0
Restricted cash held as a certificate of deposit		0
Warrant liability		0
Fair Value, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Deposit held as a certificate of deposit	0	0
Total assets	0	0
Contingent earnout liability	342	561
Total liabilities	$ 342	10,119
Restricted cash held as a certificate of deposit		0
Warrant liability		$ 9,558

Note 4 - Fair Value Measureme_4

Note 4 - Fair Value Measurements - Fair Value of Warrant Liability (Details) - USD ($) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Fair value of warrant liability at December 31, 2021	$ 9,558	$ 0	$ 0
Reclassification of warrant liability to equity	(7,502)
Fair value of warrant liability at March 31, 2022	0		9,558
Fair value of contingent liability at December 31, 2021	561
Decrease in fair value of contingent liability	(219)	$ 0
Fair value of contingent liability at March 31, 2022	342		561
Warrant Liability [Member]
Decrease in fair value of 2021 Warrants	$ (2,056)		(4,614)
Fair value of 2021 Warrants issued			$ 14,172

Note 5 - Prepaid Expenses and_3

Note 5 - Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Prepaid inventory	$ 335	$ 367
Prepaid dues and subscription	93	18
Prepaid insurance	77	138
Prepaid consultant	8	68
Prepaid patents	8	9
Prepaid sales rebates	3	19
Prepaid rent	0	14
Other	228	145
Total prepaid expenses and other current assets	$ 752	$ 778

Note 6 - Inventory - Summary of

Note 6 - Inventory - Summary of Inventory (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Raw materials and supplies	$ 1,446	$ 1,179
Finished goods	2,861	2,682
Less: Reserve for excess and obsolete inventory	(522)	(641)
Total inventory, net	$ 3,785	$ 3,220

Note 7 - Property and Equipme_3

Note 7 - Property and Equipment (Details Textual) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Depreciation, Total	$ 30
Depreciation, Depletion and Amortization, Total	$ 30	$ 9

Note 7 - Property and Equipme_4

Note 7 - Property and Equipment - Summary of Property and Equipment (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Property and equipment, at cost	$ 858	$ 834
Less: accumulated depreciation and amortization	(671)	(641)
Total property and equipment, net	187	193
Office and Laboratory Equipment [Member]
Property and equipment, at cost	20	20
Furniture and Fixtures [Member]
Property and equipment, at cost	157	157
Computer Equipment and Software [Member]
Property and equipment, at cost	464	464
Production Equipment [Member]
Property and equipment, at cost	138	114
Leasehold Improvements [Member]
Property and equipment, at cost	$ 79	$ 79

Note 8 - Goodwill (Details Text

Note 8 - Goodwill (Details Textual) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Goodwill, Impairment Loss	$ 0
Goodwill, Ending Balance	$ 4,528	$ 4,528

Note 9 - Other Intangible Ass_3

Note 9 - Other Intangible Assets (Details Textual) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Amortization of Intangible Assets	$ 91	$ 0

Note 9 - Other Intangible Ass_4

Note 9 - Other Intangible Assets - Schedule of Finite-Lived Intangible Assets (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Amortizable intangible assets, gross	$ 5,260	$ 5,260
Amortizable intangible assets, accumulated amortization	(151)	(60)
Amortizable intangible assets, net	3,029
Total other intangible assets, net	5,109	5,200
Trade Names [Member]
Trade names	2,080	2,080
Customer Relationships [Member]
Amortizable intangible assets, gross	290	290
Amortizable intangible assets, accumulated amortization	(17)	(7)
Amortizable intangible assets, net	273	283
Trade Secrets [Member]
Amortizable intangible assets, gross	2,890	2,890
Amortizable intangible assets, accumulated amortization	(134)	(53)
Amortizable intangible assets, net	$ 2,756	$ 2,837

Note 9 - Other Intangible Ass_5

Note 9 - Other Intangible Assets - Schedule of Finite-Lived Intangible Assets, Future Amortization Expense (Details) $ in Thousands	Mar. 31, 2022USD ($)
2022	$ 272
2023	363
2024	363
2025	363
2026	363
Thereafter	1,305
Total	$ 3,029

Note 10 - Accrued Liabilities -

Note 10 - Accrued Liabilities - Summary of Accrued Liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Contract liabilities (see Note 16)	$ 1,914	$ 1,289
Employee payroll and benefits	397	443
Audit services	95	0
Other	357	360
Total accrued liabilities	$ 2,763	$ 2,092

Note 11 - Line of Credit (Detai

Note 11 - Line of Credit (Details Textual) - Line of Credit [Member] - Bank Midwest [Member] - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Nov. 06, 2021
Line of Credit Facility, Maximum Borrowing Capacity		$ 500
Long-term Line of Credit, Total	$ 0
Debt Instrument, Base Floor	5.00%
Prime Rate [Member]
Debt Instrument, Basis Spread on Variable Rate	1.50%

Note 12 - Commitments and Con_3

Note 12 - Commitments and Contingencies (Details Textual)	Jan. 22, 2021shares	Mar. 31, 2022ft²shares
Class of Warrant or Right, Issued During Period (in shares)		37,500,000
TLF Bio Innovation, Related Party Warrants [Member]
Class of Warrant or Right, Issued During Period (in shares)	15,000
Riverside, Missouri [Member]
Area of Real Estate Property (Square Foot) | ft²		19,136

Note 12 - Commitments and Con_4

Note 12 - Commitments and Contingencies - Lease Expense (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Operating lease cost	$ 134	$ 99
Net lease cost	134	99
Operational cash flow used for operating leases	$ 111	$ 113
Weighted-average remaining lease term (in years) (Year)	5 years	1 year
Weighted-average discount rate	5.00%	12.00%

Note 12 - Commitments and Con_5

Note 12 - Commitments and Contingencies - Schedule of Future Lease Payments (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
2022	$ 430
2023	535
2024	549
Thereafter	1,166
Total future minimum lease payments	2,680
Less imputed interest	(293)
Total	2,387
Operating lease liability	465	$ 200
Operating lease liability- non-current	1,922	$ 246
Total	$ 2,387

Note 13 - Warrant Liability (De

Note 13 - Warrant Liability (Details Textual) - USD ($) shares in Thousands, $ in Thousands	Mar. 31, 2022	Dec. 31, 2021	Nov. 02, 2021	Dec. 31, 2020	Sep. 30, 2019	Aug. 13, 2019
Class of Warrant or Right, Outstanding (in shares)	44,582	7,082
The 2019 Domestic Warrants [Member]
Warrants and Rights Outstanding				$ 4,900	$ 3,100	$ 3,100
Class of Warrant or Right, Outstanding (in shares)	0
Warrants and Rights Outstanding				4,900	$ 3,100	3,100
The 2019 Foreign Warrants [Member]
Warrants and Rights Outstanding				4,200		2,000
Warrants and Rights Outstanding				4,200		2,000
The 2019 Ladenburg Warrants [Member]
Warrants and Rights Outstanding				200		100
Warrants and Rights Outstanding				$ 200		$ 100
The 2021 Warrants [Member]
Warrants and Rights Outstanding	$ 0	$ 9,600	$ 14,200
Warrants and Rights Outstanding	$ 0	$ 9,600	$ 14,200

Note 13 - Warrant Liability - T

Note 13 - Warrant Liability - The Key Assumptions Used to Value the Warrants (Details)	Dec. 31, 2021	Nov. 02, 2021	Dec. 31, 2019
Warrants assumptions	0.25	0.38
Measurement Input, Price Volatility [Member] | The 2019 Domestic Warrants [Member]
Warrants assumptions			1.78
Measurement Input, Price Volatility [Member] | The 2019 Foreign Warrants [Member]
Warrants assumptions			1.78
Measurement Input, Price Volatility [Member] | The 2019 Ladenburg Warrants [Member]
Warrants assumptions			1.86
Measurement Input, Price Volatility [Member] | The 2021 Warrants [Member]
Warrants assumptions	0.87	0.849
Measurement Input, Expected Term [Member] | The 2019 Domestic Warrants [Member]
Warrants assumptions			4.57
Measurement Input, Expected Term [Member] | The 2019 Foreign Warrants [Member]
Warrants assumptions			4.57
Measurement Input, Expected Term [Member] | The 2019 Ladenburg Warrants [Member]
Warrants assumptions			4.05
Measurement Input, Expected Term [Member] | The 2021 Warrants [Member]
Warrants assumptions	6	6.2
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Domestic Warrants [Member]
Warrants assumptions			0.0025
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Foreign Warrants [Member]
Warrants assumptions			0.0027
Measurement Input, Risk Free Interest Rate [Member] | The 2019 Ladenburg Warrants [Member]
Warrants assumptions			0.0022
Measurement Input, Risk Free Interest Rate [Member] | The 2021 Warrants [Member]
Warrants assumptions	0.0131	0.0129
Measurement Input, Expected Dividend Rate [Member] | The 2019 Domestic Warrants [Member]
Warrants assumptions			0
Measurement Input, Expected Dividend Rate [Member] | The 2019 Foreign Warrants [Member]
Warrants assumptions			0
Measurement Input, Expected Dividend Rate [Member] | The 2019 Ladenburg Warrants [Member]
Warrants assumptions			0
Measurement Input, Expected Dividend Rate [Member] | The 2021 Warrants [Member]
Warrants assumptions	0	0
Measurement Input, Share Price [Member] | The 2019 Domestic Warrants [Member]
Warrants assumptions			1.18
Measurement Input, Share Price [Member] | The 2019 Foreign Warrants [Member]
Warrants assumptions			1.54
Measurement Input, Share Price [Member] | The 2019 Ladenburg Warrants [Member]
Warrants assumptions			1.17

Note 14 - Stockholders' Equit_2

Note 14 - Stockholders' Equity (Details Textual) $ / shares in Units, $ in Thousands	Oct. 29, 2021USD ($)$ / sharesshares	Mar. 31, 2022USD ($)$ / sharesshares	Dec. 31, 2021USD ($)$ / sharesshares	Jun. 30, 2021USD ($)shares	Sep. 30, 2020USD ($)$ / sharesshares	Sep. 30, 2019USD ($)$ / sharesshares	Dec. 31, 2021USD ($)$ / sharesshares	Jan. 31, 2022shares	Nov. 02, 2021USD ($)	Jan. 15, 2021$ / sharesshares	Dec. 31, 2020USD ($)	Aug. 13, 2019USD ($)
Preferred Stock, Shares Authorized (in shares) | shares		5,000,000	5,000,000				5,000,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares		$ 0.71	$ 1.63				$ 1.63
Common Stock, Shares Authorized (in shares) | shares		150,000,000	100,000,000				100,000,000	150,000,000
Payments of Stock Issuance Costs					$ 200
Preferred Stock, Shares Outstanding, Ending Balance (in shares) | shares		13,000	14,000				14,000
Class of Warrant or Right, Issued During Period (in shares) | shares		37,500,000
Proceeds from Warrant Exercises					6,800
Ladenburg Thalmann and Co. Inc. [Member]
Payments of Stock Issuance Costs						$ 300
Private Placement, Commission Percentage						6.00%
Payments of Stock Issuance Costs, Reimbursement of Expenses						$ 60
Payments of Stock Issuance Costs, Other						$ 300
China Kington [Member]
Payments of Stock Issuance Costs					$ 200
The 2021 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares	37,500,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 0.53
Warrants and Rights Outstanding		$ 0	$ 9,600				$ 9,600		$ 14,200
The 2019 Domestic Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares						4,198,566
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares						$ 1.15
Warrants and Rights Outstanding						$ 3,100					$ 4,900	$ 3,100
Payments of Stock Issuance Costs Allocated to Warrants						200
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs						$ 300
Class of Warrant or Right, Issued During Period (in shares) | shares						4,198,566
The 2019 Ladenburg Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares						167,942
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares					$ 0.99	$ 1.25
Warrants and Rights Outstanding											200	100
Payments of Stock Issuance Costs Allocated to Warrants						$ 59
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs						$ 65
Class of Warrant or Right, Issued During Period (in shares) | shares						167,942
The 2019 Foreign Warrants [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares					$ 0.99
Warrants and Rights Outstanding											$ 4,200	$ 2,000
Exercise of Warrants, Commission, Percent					6.00%
New Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares					6,898,566
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares					$ 1.65
Warrants and Rights Outstanding, Term (Year)					5 years 6 months
TLF Bio Innovation 2021 Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares) | shares										15,000
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares										$ 0.6718
Warrants and Rights Outstanding, Term (Year)										5 years
Conversion of Series B Preferred Stock to Common Stock [Member]
Adjustments to Additional Paid in Capital, Beneficial Conversion Feature Upon Issuance of Stock			$ 700
The 2021 Private Placement Program [Member]
Payments of Stock Issuance Costs							1,700
Payments of Stock Issuance Costs Allocated to Warrants							1,600
The 2021 Private Placement Program [Member] | Conversion of Series B Preferred Stock to Common Stock [Member]
Preferred Stock, Convertible, Shares Issuable (in shares) | shares	37,500,000
Preferred Stock, Convertible, Conversion Price (in dollars per share) | $ / shares	$ 0.40
Preferred Stock, Convertible, Conversion Ratio	2,500
Maximum Percentage of Common Stock Outstanding	19.99%
Preferred Stock, Convertible, Maximum Common Stock Shares Converted (in shares) | shares	8,984,178
Conversion of Stock, Shares Converted (in shares) | shares		1,461
Conversion of Stock, Shares Issued (in shares) | shares		3,652,500
Convertible Preferred Stock, Shares Issued upon Conversion (in shares) | shares		2,500
ATM Program [Member]
Stock Issued During Period, Shares, New Issues (in shares) | shares				2,672,000
Payments of Stock Issuance Costs				$ 100
Proceeds from Issuance of Common Stock				$ 1,800
August 2019 Common Stock Purchase Agreement [Member]
Stock Issued During Period, Shares, New Issues (in shares) | shares						4,198,566
Payments of Stock Issuance Costs						$ 500
Proceeds from Issuance of Stock and Warrants						$ 4,200
Series B Preferred Stock [Member] | The 2021 Private Placement Program [Member]
Stock Issued During Period, Shares, New Issues (in shares) | shares	15,000
Preferred Stock, Convertible, Shares Issuable (in shares) | shares	37,500,000
Proceeds from Issuance of Preferred Stock and Preference Stock	$ 14,900
Preferred Stock, Purchase Price (in dollars per share) | $ / shares	$ 1,000
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs							$ 100

Note 14 - Stockholders' Equit_3

Note 14 - Stockholders' Equity - Outstanding Warrants (Details) shares in Thousands	3 Months Ended
	Mar. 31, 2022$ / sharesshares
Outstanding warrants (in shares) | shares	7,082
Outstanding warrants, weighted-average exercise price (in dollars per share) | $ / shares	$ 1.63
Warrants granted (in shares) | shares	37,500
Warrants granted, weighted average exercise price (in dollars per share) | $ / shares	$ 0.53
Outstanding warrants (in shares) | shares	44,582
Outstanding warrants, weighted-average exercise price (in dollars per share) | $ / shares	$ 0.71

Note 15 - Equity-based Compen_3

Note 15 - Equity-based Compensation (Details Textual) - USD ($) $ in Thousands	Jan. 15, 2021	Mar. 31, 2017	Oct. 31, 2007	Mar. 31, 2022	Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period (in shares)				0
Proceeds from Stock Options Exercised				$ 0
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total				$ 1,100
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition (Year)				2 years 3 months
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)				332,000
Share-Based Payment Arrangement, Expense				$ 184	$ 183
Share-Based Payment Arrangement, Nonemployee [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)				0	0
Share-Based Payment Arrangement, Expense					$ 53
Employees and Directors [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross (in shares)				332,000	55,000
Share-Based Payment Arrangement, Option [Member]
Share-Based Payment Arrangement, Expense				$ 184	$ 130
Restricted Stock [Member] | Employees and Directors [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period (in shares)				0	0
The 2007 Omnibus Incentive Plan [Member] | Maximum [Member] | Incentive Stock Options (ISOs) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)			10 years
The 2017 Omnibus Incentive Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized (in shares)		2,318,486
Share-based Compensation Arrangement by Share-based Payment Award, Annual Increase in Shares Authorized, Percentage of Outstanding Common Stock		4.00%
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized (in shares)	1,671,303
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant (in shares)				1,525,680
The 2017 Omnibus Incentive Plan [Member] | Incentive Stock Options (ISOs) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percentage of Stock Owned by Shareholder, Minimum		10.00%
The 2017 Omnibus Incentive Plan [Member] | Share-Based Payment Arrangement, Option [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)		4 years
The 2017 Omnibus Incentive Plan [Member] | Maximum [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)		10 years
The 2017 Omnibus Incentive Plan [Member] | Maximum [Member] | Incentive Stock Options (ISOs) [Member] | Shareholder of More Than 10% [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)		5 years
The 2017 Omnibus Incentive Plan [Member] | Minimum [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent		100.00%
The 2017 Omnibus Incentive Plan [Member] | Minimum [Member] | Incentive Stock Options (ISOs) [Member] | Shareholder of More Than 10% [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent		110.00%

Note 15 - Equity-based Compen_4

Note 15 - Equity-based Compensation - Stock Options Outstanding (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Dec. 31, 2021
Outstanding awards (in shares)	4,449
Outstanding, weighted-average exercise price (in dollars per share)	$ 1.39
Outstanding, weighted-average remaining contractual life (Year)	7 years 7 months 6 days
Outstanding, aggregate intrinsic value	$ 356	$ 460
Options granted (in shares)	332
Options granted, weighted-average exercise price (in dollars per share)	$ 0.30
Options forfeited/cancelled (in shares)	(21)
Options forfeited/cancelled, weighted-average exercise price (in dollars per share)	$ 10.94
Outstanding awards (in shares)	4,760
Outstanding, weighted-average exercise price (in dollars per share)	$ 1.27
Vested and expected to vest (in shares)	4,416
Vested and expected to vest, weighted-average exercise price (in dollars per share)	$ 1.33
Vested and expected to vest, weighted-average remaining contractual life (Year)	7 years 6 months
Vested and expected to vest, aggregate intrinsic value	$ 313
Vested (in shares)	2,218
Vested, weighted-average exercise price (in dollars per share)	$ 2.30
Vested, weighted-average remaining contractual life (Year)	5 years 9 months 18 days
Vested, aggregate intrinsic value	$ 0
Exercisable (in shares)	2,218
Exercisable, weighted-average exercise price (in dollars per share)	$ 2.30
Exercisable, weighted-average remaining contractual life (Year)	5 years 9 months 18 days
Exercisable, aggregate intrinsic value	$ 0

Note 15 - Equity-based Compen_5

Note 15 - Equity-based Compensation - Weighted-average Assumptions Used in Determining the Value of Options Granted to Employees and Directors (Details) - Employees and Directors [Member] - $ / shares	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Expected price volatility	160.47%	164.44%
Expected term (Year)	6 years 5 months 12 days	6 years 2 months 8 days
Risk-free interest rate	1.63%	1.09%
Dividend yield	0.00%	0.00%
Weighted-average fair value of options granted during the period (in dollars per share)	$ 0.29	$ 1.04

Note 15 - Equity-based Compen_6

Note 15 - Equity-based Compensation - Summary of Stock-based Compensation Expense Included in Results of Operations (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Stock-based compensation expense	$ 184	$ 183
Research and Development Expense [Member]
Stock-based compensation expense	4	4
Selling and Marketing Expense [Member]
Stock-based compensation expense	12	31
General and Administrative Expense [Member]
Stock-based compensation expense	$ 168	$ 148

Note 16 - License, Collaborat_3

Note 16 - License, Collaboration and Distribution Agreements (Details Textual) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Revenue from Contract with Customer, Including Assessed Tax	$ 2,629	$ 1,807
Avenova Direct [Member]
Revenue from Contract with Customer, Including Assessed Tax	1,400	1,200
DERMAdoctor [Member]
Contract with Customer, Liability, Total	600		$ 400
Revenue from Contract with Customer, Including Assessed Tax	891	0
McKesson Corporation [Member] | Avenova Product [Member]
Contract with Customer, Liability, Revenue Recognized	199	$ 122
McKesson Corporation [Member] | Avenova Product [Member] | Accounts Payable and Accrued Liabilities [Member]
Contract with Customer, Liability, Total	1,300		900
McKesson Corporation [Member] | Avenova Product [Member] | Prepaid Expenses and Other Current Assets [Member]
Contract with Customer, Rebate Liability, Current	$ 3		$ 19

Note 16 - License, Collaborat_4

Note 16 - License, Collaboration and Distribution Agreements - Changes in Assets and Liabilities (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2022USD ($)
Contract Liabilities: Deferred Revenue, Balance at beginning of the period	$ 2
Contract Liabilities: Deferred Revenue, additions	69
Contract Liabilities: Deferred Revenue, deductions	(2)
Contract Liabilities: Deferred Revenue, Balance at the end of the period	69
Contract Liabilities: Accrued Liabilities,Balance at beginning of the period	1,270
Contract Liabilities: Accrued Liabilities, additions	842
Contract Liabilities: Accrued Liabilities, deductions	(201)
Contract Liabilities: Accrued Liabilities, Balance at the end of the period	1,911
Contract Liabilities, Balance at beginning of the period	1,272
Contract Liabilities, additions	911
Contract Liabilities, deductions	(203)
Contract Liabilities, Balance at the end of the period	$ 1,980

Note 16 - License, Collaborat_5

Note 16 - License, Collaboration and Distribution Agreements - Total Revenues (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Total sales, net	$ 2,629	$ 1,807
Transferred over Time [Member]
Total sales, net	201	575
Transferred at Point in Time [Member]
Total sales, net	$ 2,428	$ 1,232

Note 17 - Employee Benefit Pl_2

Note 17 - Employee Benefit Plan (Details Textual) - USD ($) $ in Thousands	Jan. 01, 2022	Dec. 31, 2021
The 401(k) Plan [Member]
Defined Contribution Plan, Employer Discretionary Contribution Amount		$ 0
The 401K Plan Contribution Level One [Member]
Defined Contribution Plan, Employer Matching Contribution, Percent of Match	100.00%
Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay	3.00%
The 401K Plan Contribution Level Two [Member]
Defined Contribution Plan, Employer Matching Contribution, Percent of Match	50.00%
Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay	2.00%

Note 18 - Related Party Trans_3

Note 18 - Related Party Transactions (Details Textual) - USD ($) $ in Millions	Mar. 31, 2022	Dec. 31, 2021
Accounts Receivable, Related Parties	$ 0.1	$ 0.1

Note 18 - Related Party Trans_4

Note 18 - Related Party Transactions - Related Party Revenue, Cost of Goods Sold, and Expenses (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Total related party revenue	$ 148	$ 0
Cost of goods sold	134	0
NeutroPhase [Member]
Total related party revenue	148	0
Cost of goods sold	$ 134	$ 0

Note 19 - Paycheck Protection_2

Note 19 - Paycheck Protection Program (Details Textual) - USD ($) $ in Thousands	May 24, 2021	May 06, 2020	Mar. 31, 2022	Dec. 31, 2020
Paycheck Protection Program CARES Act [Member]
Other Nonoperating Income			$ 0	$ 900
Paycheck Protection Program CARES Act [Member] | Wells Fargo Bank [Member]
Proceeds from Issuance of Long-term Debt, Total		$ 900
Gain (Loss) on Extinguishment of Debt, Total	$ 900

Note 20 - Segment Reporting (De

Note 20 - Segment Reporting (Details Textual)	3 Months Ended
	Mar. 31, 2022
Number of Reportable Segments	2

Note 20 - Segment Reporting - F

Note 20 - Segment Reporting - Financial Information by Segment (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenue from Contract with Customer, Including Assessed Tax	$ 2,629	$ 1,807
Total sales, net	2,629	1,807
Operating Loss	(2,382)	(1,520)
Optical and Wound Care [Member]
Revenue from Contract with Customer, Including Assessed Tax	1,738	1,807
Total sales, net	1,738	1,807
Operating Loss	(2,039)	(1,520)
Skincare [Member]
Revenue from Contract with Customer, Including Assessed Tax	891	0
Total sales, net	891	$ 0
Operating Loss	$ (343)