| Cover Page | Feb. 24, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Document Period End Date | Feb. 24, 2022 |
| Entity Registrant Name | PACIRA BIOSCIENCES, INC. |
| Entity Incorporation, State or Country Code | DE |
| Entity File Number | 001-35060 |
| Entity Tax Identification Number | 51-0619477 |
| Entity Address, Address Line One | 5401 West Kennedy Boulevard, Suite 890 |
| Entity Address, City or Town | Tampa |
| Entity Address, State or Province | FL |
| Entity Address, Postal Zip Code | 33609 |
| City Area Code | 813 |
| Local Phone Number | 553-6680 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Entity Emerging Growth Company | false |
| Title of 12(b) Security | Common Stock, par value $0.001 per share |
| Trading Symbol | PCRX |
| Security Exchange Name | NASDAQ |
| Entity Central Index Key | 0001396814 |
| Amendment Flag | false |
