| Pay vs Performance Disclosure - USD ($) | 12 Months Ended |
| Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020 |
| Pay vs Performance Disclosure [Table] | | | |
| Pay vs Performance [Table Text Block] | Pay Versus Performance The following table sets forth information concerning the relationship between executive compensation actually paid to our CEO and other NEOs (our “non-PEO NEOs”) and certain financial performance measures of the company for our fiscal years ending in December 31, 2020, 2021 and 2022: | | |
| Peer Group Issuers, Footnote [Text Block] | The peer group used for this column is the Nasdaq Biotechnology TR Index, which is the peer group used in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report on Form 10-K, filed with the SEC on February 28, 2023. | | |
| PEO Total Compensation Amount | $ 7,596,268 | $ 5,771,962 | $ 5,453,681 |
| PEO Actually Paid Compensation Amount | (2,644,337) | (2,080,019) | 18,509,831 |
| Non-PEO NEO Average Total Compensation Amount | 2,122,384 | 2,086,486 | 1,583,094 |
| Non-PEO NEO Average Compensation Actually Paid Amount | $ (217,100) | (57,132) | 4,826,492 |
| Compensation Actually Paid vs. Total Shareholder Return [Text Block] | Chart 1: Compensation Actually Paid vs. Total Stockholder Return | | |
| Compensation Actually Paid vs. Net Income [Text Block] | Chart 2: Compensation Actually Paid vs. Net Loss | | |
| Compensation Actually Paid vs. Company Selected Measure [Text Block] | Chart 3: Compensation Actually Paid vs. Revenue | | |
| Tabular List [Table Text Block] | Tabular List of Financial Performance Measures We consider the following to be the most important financial performance measures to link CAP to NEOs, for 2022, to company performance. • Revenue • Gross Margins • Operating Expenses • Bookings of CosMx SMI instruments (important non-financial performance measure) | | |
| Total Shareholder Return Amount | $ 28.65 | 153.70 | 240.4 |
| Peer Group Total Shareholder Return Amount | 113.65 | 127.55 | 126.42 |
| Net Income (Loss) | $ (159,543) | $ (115,254) | $ (110,078) |
| Company Selected Measure Amount | 127,262 | 145,085 | 117,316 |
| PEO Name | Mr. Gray | | |
| Measure [Axis]: 1 | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Measure Name | Revenue | | |
| Measure [Axis]: 2 | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Measure Name | Gross Margins | | |
| Measure [Axis]: 3 | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Measure Name | Operating Expenses | | |
| Measure [Axis]: 4 | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Measure Name | Bookings of CosMx SMI instruments (important non-financial performance measure) | | |
| PEO [Member] | Less Reported Fair Value Of Equity Awards [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | $ (6,536,080) | $ (4,650,260) | $ (4,312,551) |
| PEO [Member] | AddYearEndFairValueOfEquityAwardsGrantedInTheYear [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 629,327 | 1,886,373 | 5,780,489 |
| PEO [Member] | ChangeInFairValueOfEquityAwardsGrantedInPriorYearsThatVestedInTheYear [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | (2,633,535) | (4,436,382) | 10,811,670 |
| PEO [Member] | Adjust For Fair Value At Vesting Of Option Awards And Stock Awards Granted In Fiscsal Year That Vested During Fiscal Year [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 0 | 0 | 0 |
| PEO [Member] | Adjust for Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | (1,700,317) | (651,712) | 776,542 |
| PEO [Member] | Fair Value as of Prior Fiscal Year End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 0 | 0 | 0 |
| PEO [Member] | Value Of Dividends Or Other Earnings Paid On Stock Or Option Awards Not Otherwise Reflected In Fair Value Or Total Compensation [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 0 | 0 | 0 |
| Non-PEO NEO [Member] | Less Reported Fair Value Of Equity Awards [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | (1,630,737) | (1,466,658) | (966,672) |
| Non-PEO NEO [Member] | AddYearEndFairValueOfEquityAwardsGrantedInTheYear [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 226,326 | 646,734 | 1,313,686 |
| Non-PEO NEO [Member] | ChangeInFairValueOfEquityAwardsGrantedInPriorYearsThatVestedInTheYear [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | (593,629) | (1,108,510) | 2,675,446 |
| Non-PEO NEO [Member] | Adjust For Fair Value At Vesting Of Option Awards And Stock Awards Granted In Fiscsal Year That Vested During Fiscal Year [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 0 | 0 | 0 |
| Non-PEO NEO [Member] | Adjust for Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | (341,444) | (215,184) | 220,938 |
| Non-PEO NEO [Member] | Fair Value as of Prior Fiscal Year End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | 0 | 0 | 0 |
| Non-PEO NEO [Member] | Value Of Dividends Or Other Earnings Paid On Stock Or Option Awards Not Otherwise Reflected In Fair Value Or Total Compensation [Member] | | | |
| Pay vs Performance Disclosure [Table] | | | |
| Adjustment to Compensation Amount | $ 0 | $ 0 | $ 0 |
