| Cover Page - USD ($) $ in Millions | 12 Months Ended | ||
| Dec. 31, 2021 | Apr. 28, 2022 | Jun. 30, 2021 | |
| Cover [Abstract] | |||
| Document Type | 10-K/A | ||
| Amendment Flag | true | ||
| Document Period End Date | Dec. 31, 2021 | ||
| Document Fiscal Year Focus | 2021 | ||
| Document Fiscal Period Focus | FY | ||
| Entity Registrant Name | ZYMEWORKS INC. | ||
| Trading Symbol | ZYME | ||
| Entity Central Index Key | 0001403752 | ||
| Current Fiscal Year End Date | --12-31 | ||
| Entity Current Reporting Status | Yes | ||
| Entity Filer Category | Large Accelerated Filer | ||
| Entity Small Business | false | ||
| Entity Shell Company | false | ||
| Entity Emerging Growth Company | false | ||
| Entity Address, State or Province | BC | ||
| Entity Interactive Data Current | Yes | ||
| Title of 12(b) Security | Common shares, no par value per share | ||
| Security Exchange Name | NYSE | ||
| Entity Common Stock, Shares Outstanding | 57,771,204 | ||
| Entity Voluntary Filers | No | ||
| Entity Well-known Seasoned Issuer | Yes | ||
| Entity Public Float | $ 1,590.8 | ||
| Entity File Number | 001-38068 | ||
| Entity Incorporation, State or Country Code | Z4 | ||
| Entity Tax Identification Number | 98-1398788 | ||
| Entity Address, Address Line One | Suite 800 | ||
| Entity Address, Address Line Two | 114 East 4th Avenue | ||
| Entity Address, City or Town | Vancouver | ||
| Entity Address, Postal Zip Code | V5T 1G4 | ||
| Local Phone Number | 678-1388 | ||
| City Area Code | 604 | ||
| Document Annual Report | true | ||
| Document Transition Report | false | ||
| Auditor Name | KPMG LLP | ||
| Auditor Firm ID | 85 | ||
| Auditor Location | Vancouver, Canada | ||
| ICFR Auditor Attestation Flag | true | ||
| Amendment Description | EXPLANATORY NOTE This Amendment No. 1 on Form 10-K/A (this “Amendment”), amends Zymeworks Inc.’s (the “Company,” “Zymeworks,” “we,” “us,” and “our”) annual report on Form 10-K for the year ended December 31, 2021, originally filed with the Securities and Exchange Commission, or SEC, on February 24, 2022 (the “Original Filing”). We are amending and refiling Part III to include information required by Items 10, 11, 12, 13 and 14 because our definitive proxy statement will not be filed within 120 days after December 31, 2021, the end of the fiscal year covered by our annual report on Form 10-K. Pursuant to the rules of the SEC, we have also included as exhibits currently dated certifications required under Section 302 of The Sarbanes-Oxley Act of 2002. Because no financial statements are contained within this Amendment, we are not including certifications pursuant to Section 906 of The Sarbanes-Oxley Act of 2002. We are amending and refiling Part IV to reflect the inclusion of those certifications, along with any changes to Part IV that occurred after the date of the Original Filing. In addition, we made certain revisions to the cover page, including the deletion of the reference to our proxy statement and inclusion of updated outstanding share information. Except as described above, no other changes have been made to the Original Filing. Except as otherwise indicated herein, this Amendment continues to speak as of the date of the Original Filing, and we have not updated the disclosures contained therein to reflect any events that occurred subsequent to the date of the Original Filing. The filing of this Amendment is not a representation that any statements contained in items of our annual report on Form 10-K other than Part III, Items 10 through 14, Part IV and the aforementioned portions of the cover page are true or complete as of any date subsequent to the Original Filing. |
