EMI Holding 10-Q 21 Aug 17 2017 Q2 Quarterly report Financial data

Document and Entity Information

Document and Entity Information - shares	6 Months Ended
	Jun. 30, 2017	Aug. 17, 2017
Document And Entity Information
Entity Registrant Name	EMMAUS LIFE SCIENCES, INC.
Entity Central Index Key	1,420,031
Document Type	10-Q
Trading Symbol	EMMA
Document Period End Date	Jun. 30, 2017
Amendment Flag	false
Current Fiscal Year End Date	--12-31
Entity a Well-known Seasoned Issuer	No
Entity a Voluntary Filer	No
Entity's Reporting Status Current	Yes
Entity Filer Category	Smaller Reporting Company
Entity Common Stock, Shares Outstanding		34,845,969
Document Fiscal Period Focus	Q2
Document Fiscal Year Focus	2,017

CONSOLIDATED BALANCE SHEETS (Un

CONSOLIDATED BALANCE SHEETS (Unaudited) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
CURRENT ASSETS
Cash and cash equivalents	$ 5,087,509	$ 1,317,340
Investment capital reserve	31,841,500
Accounts receivable	11,065	14,221
Inventories, net	270,811	166,209
Investment in marketable securities	10,499,001	10,917,301
Marketable securities, pledged to creditor	185,653	179,765
Prepaid expenses and other current assets	296,639	129,204
Total current assets	48,192,178	12,724,040
PROPERTY AND EQUIPMENT, Net	122,200	53,730
OTHER ASSETS
Deposits	109,190	214,808
Total other assets	109,190	214,808
Total Assets	48,423,568	12,992,578
CURRENT LIABILITIES
Accounts payable and accrued expenses	6,706,528	3,201,154
Other current liability	36,867,334
Notes payable, net	4,376,383	4,094,429
Notes payable to related parties, net	1,582,510	1,924,850
Convertible notes payable, net	9,640,669	9,205,007
Convertible notes payable to related parties, net	474,000	474,000
Total current liabilities	59,647,424	18,899,440
LONG-TERM LIABILITIES
Deferred rent	49,411	57,081
Warrant derivative liabilities	16,262,000	10,600,000
Convertible notes payable, net	212,297	997,957
Total long-term liabilities	16,523,708	11,655,038
Total Liabilities	76,171,132	30,554,478
COMMITMENTS AND CONTINGENCIES
STOCKHOLDERS' DEFICIT
Preferred stock - par value $0.001 per share, 20,000,000 shares authorized, none issued and outstanding
Common stock - par value $0.001 per share, 100,000,000 shares authorized, 34,742,219 shares and 34,701,219 shares issued and outstanding at June 30, 2017 and December 31, 2016, respectively	34,742	34,701
Additional paid-in capital	101,123,041	92,614,801
Accumulated other comprehensive loss	(3,874,163)	(3,450,746)
Accumulated deficit	(125,031,184)	(106,760,656)
Total stockholders' deficit	(27,747,564)	(17,561,900)
Total Liabilities and Stockholders' Deficit	$ 48,423,568	$ 12,992,578

CONSOLIDATED BALANCE SHEETS (U3

CONSOLIDATED BALANCE SHEETS (Unaudited) (Parenthetical) - $ / shares	Jun. 30, 2017	Dec. 31, 2016
Statement of Financial Position [Abstract]
Preferred stock, par value (in dollars per share)	$ 0.001	$ 0.001
Preferred stock, authorized	20,000,000	20,000,000
Preferred stock, issued	0	0
Preferred stock, outstanding	0	0
Common stock, par value (in dollars per share)	$ 0.001	$ 0.001
Common stock, authorized	100,000,000	100,000,000
Common stock, issued	34,742,219	34,701,219
Common stock, outstanding	34,742,219	34,701,219

CONSOLIDATED STATEMENTS OF COMP

CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Income Statement [Abstract]
REVENUES, net	$ 118,641	$ 172,681	$ 226,118	$ 252,080
COST OF GOODS SOLD	45,252	83,006	93,512	111,072
GROSS PROFIT	73,389	89,675	132,606	141,008
OPERATING EXPENSES
Research and development	1,196,630	584,695	1,952,358	1,086,996
Selling	89,638	85,054	191,299	178,634
General and administrative	3,514,302	2,255,506	6,313,342	4,548,428
Total operating expenses	4,800,570	2,925,255	8,456,999	5,814,058
LOSS FROM OPERATIONS	(4,727,181)	(2,835,580)	(8,324,393)	(5,673,050)
OTHER INCOME (EXPENSE)
Change in fair value of warrant derivative liabilities	(4,434,000)	806,110	(5,662,000)	(56,890)
Interest and other loss	(8,711)	(33,640)	(21,941)	(59,472)
Interest expense	(2,605,903)	(1,079,353)	(4,259,794)	(1,810,555)
Total other income expense	(7,048,614)	(306,883)	(9,943,735)	(1,926,917)
LOSS BEFORE INCOME TAXES	(11,775,795)	(3,142,463)	(18,268,128)	(7,599,967)
INCOME TAXES			2,400	2,400
NET LOSS	(11,775,795)	(3,142,463)	(18,270,528)	(7,602,367)
COMPONENTS OF OTHER COMPREHENSIVE INCOME (LOSS)
Unrealized holding loss on marketable securities	(461,382)	(26,690)	(412,412)	(785)
Unrealized foreign currency translation income (loss)	602	16,609	(11,005)	27,613
Other comprehensive income loss	(460,780)	(10,081)	(423,417)	26,828
COMPREHENSIVE LOSS	$ (12,236,575)	$ (3,152,544)	$ (18,693,945)	$ (7,575,539)
NET LOSS PER COMMON SHARE (in dollars per share)	$ (0.34)	$ (0.11)	$ (.53)	$ (0.27)
WEIGHTED AVERAGE COMMON SHARES OUTSTANDING (in shares)	34,736,681	28,564,216	34,721,633	28,515,007

CONSOLIDATED STATEMENT OF CHANG

CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' DEFICIT (UNAUDITED) - 6 months ended Jun. 30, 2017 - USD ($)	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Other Comprehensive Income (Loss) [Member]	Accumulated Deficit [Member]	Total
Balance, beginning at Dec. 31, 2016	$ 34,701	$ 92,614,801	$ (3,450,746)	$ (106,760,656)	$ (17,561,900)
Balance, beginning (in shares) at Dec. 31, 2016	34,701,219
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issued for cash	$ 41	311,559			311,600
Stock issued for cash (in shares)	41,000
Beneficial conversion feature related to convertible and promissory notes payable		5,392,922			5,392,922
Share-based compensation		2,803,759			2,803,759
Unrealized loss on marketable securities, net of tax			(412,412)		(412,412)
Foreign currency translation effect			(11,005)		(11,005)
Net loss				(18,270,528)	(18,270,528)
Balance, ending at Jun. 30, 2017	$ 34,742	$ 101,123,041	$ (3,874,163)	$ (125,031,184)	$ (27,747,564)
Balance, ending (in shares) at Jun. 30, 2017	34,742,219

CONSOLIDATED STATEMENTS OF CASH

CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)	6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016
CASH FLOWS FROM OPERATING ACTIVITIES
Net loss	$ (18,270,528)	$ (7,602,367)
Adjustments to reconcile net loss to net cash flows used in operating activities
Depreciation and amortization	9,357	7,402
Amortization of discount of convertible notes	3,310,318	771,704
Foreign exchange adjustments on convertible notes and notes payable	85,096	339,206
Share-based compensation	2,803,759	975,205
Change in fair value of warrant derivative liabilities	5,662,000	56,890
Net changes in operating assets and liabilities
Investment capital reserve	(31,841,500)
Accounts receivable	3,448	52,356
Inventories	(101,225)	(14,323)
Prepaid expenses and other current assets	(147,143)	82,122
Deposits	106,821	16,859
Accounts payable and accrued expenses	4,091,074	940,127
Other current liability	36,841,500	(55,000)
Deferred rent	(7,684)	(864)
Net cash flows provided by (used in) operating activities	2,545,293	(4,430,683)
CASH FLOWS USED IN INVESTING ACTIVITIES
Purchases of property and equipment	(84,569)	(1,897)
Net cash flows used in investing activities	(84,569)	(1,897)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from notes payable issued	100,000	2,654,700
Proceeds from convertible notes payable issued	1,200,000	740,110
Payments of notes payable	(344,339)	(307,700)
Payments of convertible notes		(611,970)
Proceeds from issuance of common stock	311,600	1,799,999
Net cash flows from financing activities	1,267,261	4,275,139
Effect of exchange rate changes on cash	42,184	7,987
Net increase (decrease) in cash and cash equivalents	3,770,169	(149,454)
Cash and cash equivalents, beginning of period	1,317,340	472,341
Cash and cash equivalents, end of period	5,087,509	322,887
SUPPLEMENTAL DISCLOSURES OF CASH FLOW ACTIVITIES
Interest paid	557,998	473,619
Income taxes paid	$ 2,400	$ 2,400

BASIS OF PRESENTATION

BASIS OF PRESENTATION	6 Months Ended
	Jun. 30, 2017
Organization, Consolidation and Presentation of Financial Statements [Abstract]
BASIS OF PRESENTATION	NOTE 1 — BASIS OF PRESENTATION The Due to the uncertainty of the Company’s ability to meet its current operating and capital expenses, there is substantial doubt about the Company’s ability to continue as a going concern, as the continuation and expansion of its business is dependent upon obtaining further financing, successful and sufficient market acceptance of its products, and finally, achieving a profitable level of operations. The preparation of the consolidated financial statements requires the use of management estimates. Actual results could differ materially from those estimates.

SUMMARY OF SIGNIFICANT ACCOUNTI

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES	6 Months Ended
	Jun. 30, 2017
Accounting Policies [Abstract]
SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES	NOTE 2 — SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Refer Investment capital reserve — Inventories — Inventory by category June 30, 2017 December 31, 2016 Work-in-process $ 139,943 $ 34,462 Finished goods 130,868 131,747 $ 270,811 $ 166,209 Advertising cost — Marketable securities — As of June 30, 2017, the shares of CellSeed common stock were pledged to secure a Prepaid expenses and other current assets June 30, 2017 December 31, 2016 Prepaid insurance $ 126,750 $ 100,060 Other prepaid expenses and current assets 169,889 29,144 $ 296,639 $ 129,204 Other Current Liabilities Fair value measurements Period ended Warrant Derivative Liabilities—Stock Purchase Warrants June 30, 2017 December 31, 2016 Balance, beginning of period $ 10,600,000 $ 7,863,000 Change in fair value included in consolidated statements of comprehensive loss 5,662,000 2,737,000 Balance, end of period $ 16,262,000 $ 10,600,000 The value of the liability classified warrants, the value of warrant derivative liabilities and the change in fair value of the liability classified warrants and warrant derivative liabilities were determined using a Binomial Monte-Carlo Cliquet (aka “Ratchet”) Option Pricing Model. The model is similar to traditional Black-Scholes-type option pricing models, except that the exercise price resets at certain dates in the future. T June 30, 2017 December 31, 2016 Initial Value Stock price $ 8.20 $ 6.00 $ 3.60 Risk-free interest rate 1.27 % 1.09 % 1.72 % Expected volatility (peer group) 59.20 % 68.30 % 72.40 % Expected life (in years) 1.20 1.70 5.00 Number outstanding 3,320,501 3,320,501 3,320,501 Balance, end of period: Liability classified warrants $ — $ — $ 7,541,000 Warrant derivative liabilities $ 16,262,000 $ 10,600,000 $ — Debt and related party debt Stated Original Beneficial Warrants Warrant Effective Annual Loan Conversion Issued FMV Interest Rate Term of Interest Principal Conversion Discount with Exercise Discount Including Type of Loan Loan Rate Amount Rate Amount Notes Price Amount Discounts 2016 convertible notes payable Due on demand - 2 years 10 % 10,866,291 $3.50- $4.50 3,196,544 75,000 $ 4.70 161,658 14% - 102% 2017 convertible notes payable Due on demand - 2 years 10 % 6,476,026 $3.50- $7.60 5,392,922 — $ — — 10% - 99% Total $ 17,342,317 $ 8,589,466 75,000 $ 161,658 Related party notes are disclosed as separate line items in the Company’s consolidated balance sheets. Net loss per share Recent accounting pronouncements Recognition and Measurement of Financial Assets and Financial Liabilities measured at fair value with changes in the fair value recognized through net income, (2) allow equity investments that do not have readily determinable fair values to be remeasured at fair value either upon the occurrence of an observable price change or upon identification of an impairment, (3) require assessment for impairment of equity investments without readily determinable fair values qualitatively at each reporting period, (4) eliminate the requirement to disclose the methods and significant assumptions used in calculating the fair value of financial instruments required to be disclosed for financial instruments measured at amortized cost on the balance sheet, (5) require public business entities to use the exit price notion when measuring the fair value of financial instruments for disclosure purposes, (6) require separate presentation of financial assets and financial liabilities by measurement category and form of financial asset (that is, securities or loans and receivables) on the balance sheet or the accompanying notes to the financial statements, (7) clarify that an entity should evaluate the need for a valuation allowance on a deferred tax asset related to available-for-sale securities in combination with the entity’s other deferred tax assets. The amendments in this Update are effective for the Company for fiscal years beginning after December 15, 2017, including interim periods within those years. The amendments should be applied by means of a cumulative-effect adjustment to the balance sheet as of the beginning of the fiscal year of adoption. The amendments related to equity securities without readily determinable fair values (including disclosure requirements) should be applied prospectively to equity investments that exist as of the date of adoption of the Update. The impact of the adoption of the amendments in this Update will depend on the amount of equity securities and financial instruments subject to the amendments in this Update held by the Company at the time of adoption. In February 2016, the FASB issued ASU No. 2016-02, Leases In March 2016, the FASB issued ASU 2016-09, Compensation—Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting In April 2016, the FASB issued ASU 2016-10, Revenue from Contracts with Customers (Topic 606): Identifying Performance Obligations and Licensing In August 2016, the FASB issued ASU No. 2016-15, Statement of Cash Flows (Topic 230), Classification of Certain Cash Receipts and Cash Payments In January 2017, the FASB issued ASU No. 2017-01, Business Combinations (Topic 805): Clarifying the Definition of a Business In May 2017, the FASB issued ASU No. 2017-09, Compensation — Stock Compensation (Topic 718): Scope of Modification Accounting

PROPERTY AND EQUIPMENT

PROPERTY AND EQUIPMENT	6 Months Ended
	Jun. 30, 2017
Property, Plant and Equipment [Abstract]
PROPERTY AND EQUIPMENT	NOTE 3 — PROPERTY AND EQUIPMENT Property and equipment consisted of the following at: June 30, 2017 December 31, 2016 Equipment $ 223,988 $ 175,410 Leasehold improvements 61,054 30,804 Furniture and fixtures 74,090 74,760 Subtotal 359,132 280,974 Less: accumulated depreciation (236,932 ) (227,244 ) Total $ 122,200 $ 53,730 During the three months ended June 30, 2017 and 2016, depreciation expense was $4,049 and $3,734, respectively. During the six months ended June 30, 2017 and 2016, depreciation expense was $9,357 and $7,402, respectively.

ACCOUNTS PAYABLE AND ACCRUED EX

ACCOUNTS PAYABLE AND ACCRUED EXPENSES	6 Months Ended
	Jun. 30, 2017
Payables and Accruals [Abstract]
ACCOUNTS PAYABLE AND ACCRUED EXPENSES	NOTE 4 — ACCOUNTS PAYABLE AND ACCRUED EXPENSES Accounts payable and accrued expenses consisted of the following at: June 30, 2017 December 31, 2016 Accounts payable Clinical and regulatory expenses $ 430,419 $ 145,239 Legal expenses 49,884 43,700 Consulting fees 196,394 99,800 Accounting fees 83,726 65,267 Selling expenses 20,914 60,724 Investor relations and public relations expenses — 19,931 Other vendors 106,983 41,640 Total accounts payable 888,320 476,301 Accrued interest payable, related parties 243,060 274,851 Accrued interest payable 1,253,154 1,441,450 Accrued expenses 4,030,328 716,886 Deferred salary 291,666 291,666 Total accounts payable and accrued expenses $ 6,706,528 $ 3,201,154

NOTES PAYABLE

NOTES PAYABLE	6 Months Ended
	Jun. 30, 2017
Debt Disclosure [Abstract]
NOTES PAYABLE	NOTE 5 — NOTES PAYABLE Notes payable consisted of the following at June 30, 2017 and December 31, 2016: Shares Shares Underlying Principal Discount Carrying Underlying Principal Discount Carrying Notes June Outstanding Amount Amount Notes Year Interest Rate Conversion Outstanding Amount Amount 30, December 31, December 31, December 31, December 31, Issued Range Term of Notes Price June 30, 2017 June 30, 2017 June 30, 2017 2017 2016 2016 2016 2016 Notes payable 2013 10% Due on demand — $ 890,000 $ — $ 890,000 — $ 854,900 $ — $ 854,900 — 2015 11% Due on demand — — — — — 2,406,194 — 2,406,194 — 2016 11% Due on demand — 833,335 — 833,335 — 833,335 — 833,335 — 2017 11% Due on demand — 2,653,048 — 2,653,048 — — — — — $ 4,376,383 $ — $ 4,376,383 — $ 4,094,429 $ — $ 4,094,429 — Current $ 4,376,383 $ — $ 4,376,383 — $ 4,094,429 $ — $ 4,094,429 — Non-current $ — $ — $ — — $ — $ — $ — — Notes payable - related party 2012 8% Due on demand — $ 300,000 $ — $ 300,000 — $ 500,000 $ — $ 500,000 — 2013 8% Due on demand — — — — — 50,000 — 50,000 — 2015 10% - 11% Due on demand — 410,000 — 410,000 — 514,340 — 514,340 — 2016 10% - 11% Due on demand — 860,510 — 860,510 — 860,510 — 860,510 — 2017 10% Due on demand — 12,000 — 12,000 — — — — — $ 1,582,510 $ — $ 1,582,510 — $ 1,924,850 $ — $ 1,924,850 — Current $ 1,582,510 $ — $ 1,582,510 — $ 1,924,850 $ — $ 1,924,850 — Non-current $ — $ — $ — — $ — $ — $ — — Convertible notes payable 2011 10% 5 years $3.05 $ 300,000 $ — $ 300,000 98,285 $ 300,000 $ — $ 300,000 98,285 2014 10% Due on demand - 2 years $ 3.05-$3.60 475,909 — 475,909 162,952 452,168 — 452,168 152,986 2015 10% 2 years $ 3.50-$3.60 1,543,594 3,255 1,540,339 455,630 2,904,800 104,389 2,800,411 889,115 2016 10% Due on demand — 1 year $ 3.50-$4.50 3,720,174 265,080 3,455,094 945,712 8,126,129 1,475,744 6,650,385 2,193,687 2017 10% Due on demand — 2 years $ 3.50-$7.60 7,476,026 3,394,402 4,081,624 1,988,694 — — — — $ 13,515,703 $ 3,662,737 $ 9,852,966 3,651,273 $ 11,783,097 $ 1,580,133 $ 10,202,964 3,334,073 Current $ 12,839,151 $ 3,198,482 $ 9,640,669 3,211,532 $ 10,499,303 $ 1,294,296 $ 9,205,007 2,984,161 Non-current $ 676,552 $ 464,255 $ 212,297 439,741 $ 1,283,794 $ 285,837 $ 997,957 349,912 Convertible notes payable - related party 2012 10% Due on demand $3.30 $ 254,000 $ — $ 254,000 80,807 $ 254,000 $ — $ 254,000 94,532 2015 10% 2 years $4.50 220,000 — 220,000 56,887 220,000 — 220,000 54,463 $ 474,000 $ — $ 474,000 137,694 $ 474,000 $ — $ 474,000 148,995 Current $ 474,000 $ — $ 474,000 134,556 $ 474,000 $ — $ 474,000 148,995 Non-current $ — $ — $ — 3,138 $ — $ — $ — — Grand Total $ 19,948,596 $ 3,662,737 $ 16,285,859 3,788,967 $ 18,276,376 $ 1,580,133 $ 16,696,243 3,483,068 The weighted-average stated interest rate of notes payable as of June 30, 2017 and December 31, 2016 was 10%. The weighted-average effective interest rate of notes payable for the six-month period ended June 30, 2017 and the year ended December 31, 2016 was 31% and 27%, respectively, after giving effect to discounts relating to beneficial conversion features and the fair value of warrants issued in connection with these notes. The notes payable and convertible notes payable do not have restrictive financial covenants or acceleration clauses associated with a material adverse change event. The holders of the convertible notes have the option to convert their notes into Company common stock at the stated conversion price during the term of their convertible notes. Conversion prices on these convertible notes payable range from $3.05 to $3.60 per share. Certain notes with a $4.50 or a $7.00 stated conversion price in the second year of their two-year term are subject to automatic conversion into shares of Company common stock at a conversion price equal to 80% of the initial public offering price at the time of a qualified public offering. All notes due on demand are treated as current liabilities. Contractual principal payments due on notes payable are as follows: Year Ending June 30, 2017 2017 $ 17,987,243 2018 $ 1,405,762 2019 $ 555,591 Total $ 19,948,596 The Company estimated the total fair value of any beneficial conversion feature and accompanying warrants in allocating the note proceeds. The proceeds allocated to the beneficial conversion feature were determined by taking the estimated fair value of shares issuable under the convertible notes less the fair value of the number of shares that would be issued if the conversion rate equaled the fair value of Company common stock as of the date of issuance (see Note 2). The fair value of the warrants issued in conjunction with notes was determined using the Black Scholes Merton Option Pricing Model with the following inputs for the periods ended December 31, 2016. The Company did not issue any warrants in conjunction with notes in the six months ended June 30, 2017. December 31, 2016 Stock price $ 5.00 Exercise price $ 4.50 - 4.70 Term 5 years Risk-free interest rate 1.01 - 1.28% Expected dividend yield — Expected volatility 65.4 - 69.6% In situations where the notes included both a beneficial conversion feature and a warrant, the proceeds were allocated to the warrants and beneficial conversion feature based on their respective pro rata fair values.

STOCKHOLDERS' DEFICIT

STOCKHOLDERS' DEFICIT	6 Months Ended
	Jun. 30, 2017
Stockholders' Equity Note [Abstract]
STOCKHOLDERS' DEFICIT	NOTE 6 — STOCKHOLDERS’ DEFICIT Private placement — The warrants issued in the Private Placement and the Broker Warrants entitle the holders thereof to purchase, at any time on or prior to September 11, 2018, shares of common stock of the Company at an exercise price of $3.50 per share. The warrants contain non-standard anti-dilution protection and, consequently, are being accounted for as liabilities, were originally recorded at fair value, and are adjusted to fair market value each reporting period. Because the shares of common stock underlying the Private Placement warrants and Broker Warrants were not effectively registered for resale by September 11, 2014, the warrant holders have an option to exercise the warrants using a cashless exercise feature. The shares have not been registered for resale as of June 30, 2017. The availability to warrant holders of the cashless exercise feature as of September 11, 2014 caused the then-outstanding 2,225,036 Private Placement warrants and Broker Warrants with fair value of $7,068,000 to be reclassified from liability classified warrants to warrant derivative liabilities and to continue to be remeasured at fair value each reporting period. $1.8 million, representing their intrinsic value, with this adjusted carrying value of $1.8 million being transferred to additional paid-in capital. Also on June 10, 2014, based on an offer made to holders of Private Placement warrants in connection with such exercises, the Company issued an aggregate of 1,095,465 replacement warrants to holders exercising Private Placement warrants, which replacement warrants have terms that are generally the same as the exercised warrants, including an expiration date of September 11, 2018 and an exercise price of $3.50 per share. The replacement warrants are treated for accounting purposes as liability classified warrants, and their issuance gave rise to a $3.5 million warrant exercise inducement expense based on their fair value as of issuance as determined using a Binomial Monte-Carlo Cliquet (aka Ratchet) Option Pricing Model. As of June 30, 2017, the aggregate fair value of the Private Placement warrants, replacement warrants and the Broker Warrants was $16,262,000 (see Note 2). For further details regarding registration rights associated with the Private Placement warrants, replacement warrants and Broker Warrants, see the Registration Rights section below in this footnote. A summary of outstanding warrants as of June 30, 2017 December 31, 2016 Warrants outstanding, beginning of period 5,024,668 3,530,918 Granted — 1,493,750 Exercised — — Cancelled, forfeited or expired — — Warrants outstanding, end of period 5,024,668 5,024,668 A summary of outstanding warrants by year issued and exercise price as of Outstanding Exercisable Exercise Price Number of Weighted Weighted Total Weighted At December 31, 2013 $ 3.30 50,000 0.84 $ 3.30 50,000 $ 3.30 $ 3.50 2,225,036 1.20 $ 3.50 2,225,036 $ 3.50 2013 total 2,275,036 2,275,036 At December 31, 2014 $ 3.50 1,145,465 1.23 $ 3.50 1,145,465 $ 3.50 2014 total 1,145,465 1,145,465 At December 31, 2015 $ 4.90 110,417 2.68 $ 4.90 110,417 $ 4.90 2015 total 110,417 110,417 At December 31, 2016 $ 4.50 118,750 4.00 $ 4.50 118,750 $ 4.50 $ 4.70 75,000 3.84 $ 4.70 75,000 $ 4.70 $ 5.00 1,300,000 3.86 $ 5.00 1,300,000 $ 5.00 2016 Total 1,493,750 1,493,750 June 30, 2017 Total 5,024,668 5,024,668 Stock options Summaries of outstanding options as of June 30, 2017 and December 31, 2016 are June 30, 2017 December 31, 2016 Number of Weighted- Number of Weighted- Options outstanding, beginning of period 6,955,200 $ 4.10 4,753,335 $ 3.60 Granted or deemed issued — $ — 2,596,200 $ 4.97 Exercised — $ — (15,866 ) $ 3.60 Cancelled, forfeited and expired (200,000 ) $ 5.00 (378,469 ) $ 3.91 Options outstanding, end of period 6,755,200 $ 4.07 6,955,200 $ 4.10 Options exercisable, end of period 5,299,628 $ 3.82 4,372,667 $ 3.59 Options available for future grant, end of period 2,244,800 2,044,800 During the six months ended June 30, 2017 and 2016, the Company recognized $2.8 million and $1.0 million, respectively, of share-based compensation expense arising from stock options. As of June 30, 2017, there was $5.4 million of total unrecognized compensation expense related to unvested share-based compensation arrangements granted under the Company’s 2011 Stock Incentive Plan. That expense is expected to be recognized over the weighted-average remaining period of 1.7 years. Registration rights — The Company has not yet filed a registration statement with respect to the resale of the Registrable Securities. The Company believes that it has used commercially reasonable efforts to file a registration statement with respect to the resale of Registrable Securities. Korean Private Placement be mutually agreed upon by the parties. In connection with the Letter of Agreement, KPM and Hanil entered into the Company’s standard form subscription agreement with respect to their purchase of shares which contains customary representations and warranties of the parties. On September 29, 2016, KPM and Hanil purchased and acquired from the Company 3,777,778 shares and 666,667 shares, respectively, of common stock at a price of $4.50 a share for $17 million and $3 million, respectively, for a gross total of $20 million. The Company recognized $720,000 as a reduction to its additional paid-in-capital for fees and commissions payable by the Company in connection with the transaction. Pursuant to the terms of the Letter of Agreement dated September 12, 2016, the Company invested $13 million and $1 million in capital increases by KPM and Hanil, respectively, at $15.32 and $3.68, respectively, per capital share. Pursuant to the terms of a subscription agreement dated as of September 11, 2013 among the Company and certain purchasers of shares of the Company’s common stock and warrants to purchase shares of common stock, the purchasers are entitled to participation rights with respect to the sale of shares pursuant to the Letter of Agreement. To the extent the purchasers exercise their participation rights, the Company may be obliged to sell to them a specified number of shares of common stock at the price per share and other terms set forth in the Letter of Agreement. There can be no assurance that any purchaser will exercise its participation rights or that any shares of the Company’s common stock will be issued to any purchaser.

COMMITMENTS AND CONTINGENCIES

COMMITMENTS AND CONTINGENCIES	6 Months Ended
	Jun. 30, 2017
Commitments and Contingencies Disclosure [Abstract]
COMMITMENTS AND CONTINGENCIES	NOTE 7 — COMMITMENTS AND CONTINGENCIES Distribution contract — Operating leases Future minimum lease payments under the agreements are as follows as of June 30, 2017: Year Amount 2017 (six months) $ 273,112 2018 537,600 2019 150,755 2020 2,240 $ 963,707 Management Control Acquisition Agreement — Subsequent to entering into the MCAA, the Company has been having ongoing discussions with Telcon Holdings to re-negotiate and clarify certain of the terms in the MCAA. (see Note 10) API Supply Agreement —

RELATED PARTY TRANSACTIONS

RELATED PARTY TRANSACTIONS	6 Months Ended
	Jun. 30, 2017
Related Party Transactions [Abstract]
RELATED PARTY TRANSACTIONS	NOTE 8 — RELATED PARTY TRANSACTIONS The following table sets forth information relating to the Company’s loans from related parties outstanding as of June 30, 2017: Class Lender Annual Date Term Principal Highest Amount Amount Conversion Shares Notes payable to related parties—current: Hope Hospice(1) 8 % 1/17/2012 Due on demand $ — $ 200,000 $ 200,000 $ 7,331 $ — — Hope Hospice(1) 8 % 6/14/2012 Due on demand 200,000 200,000 — 8,000 — — Hope Hospice(1) 8 % 6/21/2012 Due on demand 100,000 100,000 — 4,000 — — Hope Hospice(1) 8 % 2/11/2013 Due on demand — 50,000 50,000 1,559 — — Hope Hospice(1) 10 % 1/7/2015 Due on demand 100,000 100,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 2/20/2015 Due on demand 10,000 10,000 — — — — Yutaka Niihara(2)(3) 10 % 5/21/2015 Due on demand — 826,105 94,339 61,829 — — Masaharu & Emiko Osato(3) 11 % 12/29/2015 Due on demand 300,000 300,000 — — — — Lan T. Tran(2) 11 % 2/10/2016 Due on demand 130,510 130,510 — — — — Masaharu & Emiko Osato(3) 11 % 2/25/2016 Due on demand 400,000 400,000 — — — — Hope Hospice(1) 10 % 4/4/2016 Due on demand 50,000 50,000 — — — — Lan T. Tran(2) 10 % 4/29/2016 Due on demand 20,000 20,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 5/5/2016 Due on demand 10,000 10,000 — — — — Hope Hospice(1) 10 % 6/3/2016 Due on demand 250,000 250,000 — — — — Lan T. Tran(2) 10 % 2/9/2017 Due on demand 12,000 12,000 — — — — Sub total $ 1,582,510 $ 2,658,615 $ 344,339 $ 82,719 $ — — Convertible notes payable to related parties—current: Yasushi Nagasaki(2) 10 % 6/29/2012 Due on demand $ 254,000 $ 388,800 $ 134,800 $ 57,886 $ 3.30 80,807 Charles & Kimxa Stark(2) 10 % 10/1/2015 2 years 20,000 20,000 — — 4.50 5,222 Yutaka & Soomi Niihara(2)(3) 10 % 11/16/2015 2 years 200,000 200,000 — — 4.50 51,665 Sub total $ 474,000 $ 608,800 $ 134,800 $ 57,886 — 137,694 Total $ 2,056,510 $ 3,267,415 $ 479,139 $ 140,605 — 137,694 (1) Dr. Niihara, the Chairman and Chief Executive Officer of the Company, is also the Chief Executive Officer of Hope Hospice. (2) Officer and/or Management. (3) Director. The following table sets forth information relating to the Company’s loans from related parties outstanding as of December 31, 2016. Class Lender Annual Date Term Principal Highest Amount Amount Conversion Shares Notes payable to related parties—current: Hope Hospice(1) 8 % 1/17/2012 Due on demand $ 200,000 $ 200,000 $ — $ 20,000 $ — — Hope Hospice(1) 8 % 6/14/2012 Due on demand 200,000 200,000 — 20,000 — — Hope Hospice(1) 8 % 6/21/2012 Due on demand 100,000 100,000 — 10,000 — — Hope Hospice(1) 8 % 2/11/2013 Due on demand 50,000 50,000 — 5,000 — — Hope Hospice(1) 10 % 1/7/2015 Due on demand 100,000 100,000 — — — — Lan T. Tran(2) 10 % 2/9/2015 Due on demand 10,000 10,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 2/20/2015 Due on demand 10,000 10,000 — — — — Yutaka Niihara(2)(3) 10 % 5/21/2015 Due on demand 94,340 826,105 731,765 47,822 — — Masaharu & Emiko Osato(3) 11 % 12/29/2015 Due on demand 300,000 300,000 — — — — Lan T. Tran(2) 11 % 2/10/2016 Due on demand 130,510 130,510 — — — — Hideki & Eiko Uehara(4) 11 % 2/15/2016 Due on demand — 133,333 133,333 12,226 — — Masaharu & Emiko Osato(3) 11 % 2/25/2016 Due on demand 400,000 400,000 — — — — Hope Hospice(1) 10 % 4/4/2016 Due on demand 50,000 50,000 — — — — Willis C. Lee(2)(3) 10 % 4/8/2016 Due on demand — 79,700 79,700 1,288 — — Lan T. Tran(2) 10 % 4/29/2016 Due on demand 20,000 20,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 5/5/2016 Due on demand 10,000 10,000 — — — — Hope Hospice(1) 10 % 6/3/2016 Due on demand 250,000 250,000 — — — — Sub total $ 1,924,850 $ 2,869,648 $ 944,798 $ 116,336 $ — — Convertible notes payable to related parties—current: Yasushi Nagasaki(2) 10 % 6/29/2012 Due on demand $ 254,000 $ 388,800 $ 134,800 $ 27,824 $ 3.30 94,532 Charles & Kimxa Stark(2) 10 % 10/1/2015 2 years 20,000 20,000 — — 4.50 5,002 Yutaka & Soomi Niihara(2)(3) 10 % 11/16/2015 2 years 200,000 200,000 — — 4.50 49,461 Sub total $ 474,000 $ 608,800 $ 134,800 $ 27,824 — 148,995 Total $ 2,398,850 $ 3,478,448 $ 1,079,598 $ 144,160 — 148,995 (1) (2) (3) (4)

GEOGRAPHIC INFORMATION

GEOGRAPHIC INFORMATION	6 Months Ended
	Jun. 30, 2017
Segment Reporting [Abstract]
GEOGRAPHIC INFORMATION	NOTE 9 — GEOGRAPHIC INFORMATION For the six months ended June 30, 2017 and 2016, the Company earned revenue from countries outside of the United States as set forth in the table below: Country Revenues for the Six Months Ended June 30, 2017 % of Total Revenue for the Six Months Ended June 30, 2017 Revenues for the Six Months Ended June 30, 2016 % of Total Revenue for the Six Months Ended June 30, 2016 Japan $ 70,848 31 % $ 81,095 32 % Taiwan 113,767 50 % 134,267 53 % For the three months ended June 30, 2017 and 2016, the Company earned revenue from countries outside of the United States as set forth in the table below: Country Revenues for the Three Months Ended June 30, 2017 % of Total Revenue for the Three Months Ended June 30, 2017 Revenues for the Three Months Ended June 30, 2016 % of Total Revenue for the Three Months Ended June 30, 2016 Japan $ 42,290 36 % $ 30,021 17 % Taiwan 49,467 42 % 109,056 63 % The Company did not have any significant currency translation or foreign transaction adjustments during the six months ended June 30, 2017 or 2016.

SUBSEQUENT EVENTS

SUBSEQUENT EVENTS	6 Months Ended
	Jun. 30, 2017
Subsequent Events [Abstract]
SUBSEQUENT EVENTS	NOTE 10 — SUBSEQUENT EVENTS S Note issued after June 30, 2017 Amount Annual Interest Term of Note Conversion Price Convertible note $ 795,028 10.00 % Due on demand $ 3.50 Total $ 795,028 Subsequent to June 30, 2017, the Company issued the following: Common Shares Issued after June 30, 2017 Amount Number of Shares Issued Common shares $ 830,000 103,750 Total $ 830,000 103,750 Subsequent to June 30, 2017, the Company announced on July 7, 2017 that the U.S. Food and Drug Administration (“FDA”) approved its lead product Endari™ (pharmaceutical grade L-glutamine oral powder) to reduce the severe complications of sickle cell disease (“SCD”) in patients ages five and older. As described in Note 7, on June 12, 2017 the Company On August 8, 2017, the Company signed a Letter of Intent (“LOI”) with Eton Investment Korea (“Eton”) whereby Eton will make an equity investment of $20 million USD at a price of $12 USD per share. This investment is intended to take place before August 25, 2017. In conjunction with the signing of the LOI, the Company also signed an Agreement on New Manufacturing Plant Rights (“Plant Agreement”) with Eton and ESA affirming that these parties agree to cooperate in the construction of a new manufacturing plant in the Republic of Korea, which will be owned by ESA and operated by Eton. The Company further commits to purchasing 90% of the manufacturing plant’s annual production output. The Company also guarantees to purchase a minimum quantity at a price and quantity that is yet to be determined. Under the Plant Agreement, the Company guarantees that ESA will receive at least $5 million USD in revenue at a profit margin of 50% from the sale of

SUMMARY OF SIGNIFICANT ACCOUN17

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Policies)	6 Months Ended
	Jun. 30, 2017
Accounting Policies [Abstract]
Investment capital reserve	Investment capital reserve —
Inventories	Inventories — Inventory by category June 30, 2017 December 31, 2016 Work-in-process $ 139,943 $ 34,462 Finished goods 130,868 131,747 $ 270,811 $ 166,209
Advertising cost	Advertising cost —
Marketable securities	Marketable securities — As of June 30, 2017, the shares of CellSeed common stock were pledged to secure a $300,000 convertible note of the Company issued to Mitsubishi UFJ Capital III Limited Partnership that is due on demand and were classified as current assets, as marketable securities, pledged to creditor.
Prepaid expenses and other current assets	Prepaid expenses and other current assets June 30, 2017 December 31, 2016 Prepaid insurance $ 126,750 $ 100,060 Other prepaid expenses and current assets 169,889 29,144 $ 296,639 $ 129,204
Other Current Liabilities	Other Current Liabilities
Fair value measurements	Fair value measurements Period ended Warrant Derivative Liabilities—Stock Purchase Warrants June 30, 2017 December 31, 2016 Balance, beginning of period $ 10,600,000 $ 7,863,000 Change in fair value included in consolidated statements of comprehensive loss 5,662,000 2,737,000 Balance, end of period $ 16,262,000 $ 10,600,000 The value of the liability classified warrants, the value of warrant derivative liabilities and the change in fair value of the liability classified warrants and warrant derivative liabilities were determined using a Binomial Monte-Carlo Cliquet (aka “Ratchet”) Option Pricing Model. The model is similar to traditional Black-Scholes-type option pricing models, except that the exercise price resets at certain dates in the future. T June 30, 2017 December 31, 2016 Initial Value Stock price $ 8.20 $ 6.00 $ 3.60 Risk-free interest rate 1.27 % 1.09 % 1.72 % Expected volatility (peer group) 59.20 % 68.30 % 72.40 % Expected life (in years) 1.20 1.70 5.00 Number outstanding 3,320,501 3,320,501 3,320,501 Balance, end of period: Liability classified warrants $ — $ — $ 7,541,000 Warrant derivative liabilities $ 16,262,000 $ 10,600,000 $ —
Debt and related party debt	Debt and related party debt Stated Original Beneficial Warrants Warrant Effective Annual Loan Conversion Issued FMV Interest Rate Term of Interest Principal Conversion Discount with Exercise Discount Including Type of Loan Loan Rate Amount Rate Amount Notes Price Amount Discounts 2016 convertible notes payable Due on demand - 2 years 10 % 10,866,291 $3.50- $4.50 3,196,544 75,000 $ 4.70 161,658 14% - 102% 2017 convertible notes payable Due on demand - 2 years 10 % 6,476,026 $3.50- $7.60 5,392,922 — $ — — 10% - 99% Total $ 17,342,317 $ 8,589,466 75,000 $ 161,658 Related party notes are disclosed as separate line items in the Company’s consolidated balance sheets.
Net loss per share	Net loss per share
Recent accounting pronouncements	Recent accounting pronouncements Recognition and Measurement of Financial Assets and Financial Liabilities measured at fair value with changes in the fair value recognized through net income, (2) allow equity investments that do not have readily determinable fair values to be remeasured at fair value either upon the occurrence of an observable price change or upon identification of an impairment, (3) require assessment for impairment of equity investments without readily determinable fair values qualitatively at each reporting period, (4) eliminate the requirement to disclose the methods and significant assumptions used in calculating the fair value of financial instruments required to be disclosed for financial instruments measured at amortized cost on the balance sheet, (5) require public business entities to use the exit price notion when measuring the fair value of financial instruments for disclosure purposes, (6) require separate presentation of financial assets and financial liabilities by measurement category and form of financial asset (that is, securities or loans and receivables) on the balance sheet or the accompanying notes to the financial statements, (7) clarify that an entity should evaluate the need for a valuation allowance on a deferred tax asset related to available-for-sale securities in combination with the entity’s other deferred tax assets. The amendments in this Update are effective for the Company for fiscal years beginning after December 15, 2017, including interim periods within those years. The amendments should be applied by means of a cumulative-effect adjustment to the balance sheet as of the beginning of the fiscal year of adoption. The amendments related to equity securities without readily determinable fair values (including disclosure requirements) should be applied prospectively to equity investments that exist as of the date of adoption of the Update. The impact of the adoption of the amendments in this Update will depend on the amount of equity securities and financial instruments subject to the amendments in this Update held by the Company at the time of adoption. In February 2016, the FASB issued ASU No. 2016-02, Leases In March 2016, the FASB issued ASU 2016-09, Compensation—Stock Compensation (Topic 718): Improvements to Employee Share-Based Payment Accounting In April 2016, the FASB issued ASU 2016-10, Revenue from Contracts with Customers (Topic 606): Identifying Performance Obligations and Licensing In August 2016, the FASB issued ASU No. 2016-15, Statement of Cash Flows (Topic 230), Classification of Certain Cash Receipts and Cash Payments In January 2017, the FASB issued ASU No. 2017-01, Business Combinations (Topic 805): Clarifying the Definition of a Business In May 2017, the FASB issued ASU No. 2017-09, Compensation — Stock Compensation (Topic 718): Scope of Modification Accounting

SUMMARY OF SIGNIFICANT ACCOUN18

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)	6 Months Ended
	Jun. 30, 2017
Accounting Policies [Abstract]
Schedule of inventory	The below table presents inventory by category: Inventory by category June 30, 2017 December 31, 2016 Work-in-process $ 139,943 $ 34,462 Finished goods 130,868 131,747 $ 270,811 $ 166,209
Schedule of prepaid expenses and other current assets	Prepaid expenses and other current assets consisted of the following at June 30, 2017 and December 31, 2016: June 30, 2017 December 31, 2016 Prepaid insurance $ 126,750 $ 100,060 Other prepaid expenses and current assets 169,889 29,144 $ 296,639 $ 129,204
Schedule of changes in fair value of Level 3 liabilities	The following table presents the activity for those items measured at fair value on a recurring basis using Level 3 inputs during the six months ended June 30, 2017 and the year ended December 31, 2016: Period ended Warrant Derivative Liabilities—Stock Purchase Warrants June 30, 2017 December 31, 2016 Balance, beginning of period $ 10,600,000 $ 7,863,000 Change in fair value included in consolidated statements of comprehensive loss 5,662,000 2,737,000 Balance, end of period $ 16,262,000 $ 10,600,000
Schedule of assumptions used in the valuation of warrants	T June 30, 2017 December 31, 2016 Initial Value Stock price $ 8.20 $ 6.00 $ 3.60 Risk-free interest rate 1.27 % 1.09 % 1.72 % Expected volatility (peer group) 59.20 % 68.30 % 72.40 % Expected life (in years) 1.20 1.70 5.00 Number outstanding 3,320,501 3,320,501 3,320,501 Balance, end of period: Liability classified warrants $ — $ — $ 7,541,000 Warrant derivative liabilities $ 16,262,000 $ 10,600,000 $ —
Schedule of notes payable with beneficial conversion feature or warrants	The following table presents the effective interest rates on loans originated and refinanced in the respective periods that either had a beneficial conversion feature or an attached warrant: Stated Original Beneficial Warrants Warrant Effective Annual Loan Conversion Issued FMV Interest Rate Term of Interest Principal Conversion Discount with Exercise Discount Including Type of Loan Loan Rate Amount Rate Amount Notes Price Amount Discounts 2016 convertible notes payable Due on demand - 2 years 10 % 10,866,291 $3.50- $4.50 3,196,544 75,000 $ 4.70 161,658 14% - 102% 2017 convertible notes payable Due on demand - 2 years 10 % 6,476,026 $3.50- $7.60 5,392,922 — $ — — 10% - 99% Total $ 17,342,317 $ 8,589,466 75,000 $ 161,658

PROPERTY AND EQUIPMENT (Tables)

PROPERTY AND EQUIPMENT (Tables)	6 Months Ended
	Jun. 30, 2017
Property, Plant and Equipment [Abstract]
Schedule of property and equipment	Property and equipment consisted of the following at: June 30, 2017 December 31, 2016 Equipment $ 223,988 $ 175,410 Leasehold improvements 61,054 30,804 Furniture and fixtures 74,090 74,760 Subtotal 359,132 280,974 Less: accumulated depreciation (236,932 ) (227,244 ) Total $ 122,200 $ 53,730

ACCOUNTS PAYABLE AND ACCRUED 20

ACCOUNTS PAYABLE AND ACCRUED EXPENSES (Tables)	6 Months Ended
	Jun. 30, 2017
Payables and Accruals [Abstract]
Schedule of accounts payable and accrued expenses	Accounts payable and accrued expenses consisted of the following at: June 30, 2017 December 31, 2016 Accounts payable Clinical and regulatory expenses $ 430,419 $ 145,239 Legal expenses 49,884 43,700 Consulting fees 196,394 99,800 Accounting fees 83,726 65,267 Selling expenses 20,914 60,724 Investor relations and public relations expenses — 19,931 Other vendors 106,983 41,640 Total accounts payable 888,320 476,301 Accrued interest payable, related parties 243,060 274,851 Accrued interest payable 1,253,154 1,441,450 Accrued expenses 4,030,328 716,886 Deferred salary 291,666 291,666 Total accounts payable and accrued expenses $ 6,706,528 $ 3,201,154

NOTES PAYABLE (Tables)

NOTES PAYABLE (Tables)	6 Months Ended
	Jun. 30, 2017
Debt Disclosure [Abstract]
Schedule of notes payable	Notes payable consisted of the following at June 30, 2017 and December 31, 2016: Shares Shares Underlying Principal Discount Carrying Underlying Principal Discount Carrying Notes June Outstanding Amount Amount Notes Year Interest Rate Conversion Outstanding Amount Amount 30, December 31, December 31, December 31, December 31, Issued Range Term of Notes Price June 30, 2017 June 30, 2017 June 30, 2017 2017 2016 2016 2016 2016 Notes payable 2013 10% Due on demand — $ 890,000 $ — $ 890,000 — $ 854,900 $ — $ 854,900 — 2015 11% Due on demand — — — — — 2,406,194 — 2,406,194 — 2016 11% Due on demand — 833,335 — 833,335 — 833,335 — 833,335 — 2017 11% Due on demand — 2,653,048 — 2,653,048 — — — — — $ 4,376,383 $ — $ 4,376,383 — $ 4,094,429 $ — $ 4,094,429 — Current $ 4,376,383 $ — $ 4,376,383 — $ 4,094,429 $ — $ 4,094,429 — Non-current $ — $ — $ — — $ — $ — $ — — Notes payable - related party 2012 8% Due on demand — $ 300,000 $ — $ 300,000 — $ 500,000 $ — $ 500,000 — 2013 8% Due on demand — — — — — 50,000 — 50,000 — 2015 10% - 11% Due on demand — 410,000 — 410,000 — 514,340 — 514,340 — 2016 10% - 11% Due on demand — 860,510 — 860,510 — 860,510 — 860,510 — 2017 10% Due on demand — 12,000 — 12,000 — — — — — $ 1,582,510 $ — $ 1,582,510 — $ 1,924,850 $ — $ 1,924,850 — Current $ 1,582,510 $ — $ 1,582,510 — $ 1,924,850 $ — $ 1,924,850 — Non-current $ — $ — $ — — $ — $ — $ — — Convertible notes payable 2011 10% 5 years $3.05 $ 300,000 $ — $ 300,000 98,285 $ 300,000 $ — $ 300,000 98,285 2014 10% Due on demand - 2 years $ 3.05-$3.60 475,909 — 475,909 162,952 452,168 — 452,168 152,986 2015 10% 2 years $ 3.50-$3.60 1,543,594 3,255 1,540,339 455,630 2,904,800 104,389 2,800,411 889,115 2016 10% Due on demand — 1 year $ 3.50-$4.50 3,720,174 265,080 3,455,094 945,712 8,126,129 1,475,744 6,650,385 2,193,687 2017 10% Due on demand — 2 years $ 3.50-$7.60 7,476,026 3,394,402 4,081,624 1,988,694 — — — — $ 13,515,703 $ 3,662,737 $ 9,852,966 3,651,273 $ 11,783,097 $ 1,580,133 $ 10,202,964 3,334,073 Current $ 12,839,151 $ 3,198,482 $ 9,640,669 3,211,532 $ 10,499,303 $ 1,294,296 $ 9,205,007 2,984,161 Non-current $ 676,552 $ 464,255 $ 212,297 439,741 $ 1,283,794 $ 285,837 $ 997,957 349,912 Convertible notes payable - related party 2012 10% Due on demand $3.30 $ 254,000 $ — $ 254,000 80,807 $ 254,000 $ — $ 254,000 94,532 2015 10% 2 years $4.50 220,000 — 220,000 56,887 220,000 — 220,000 54,463 $ 474,000 $ — $ 474,000 137,694 $ 474,000 $ — $ 474,000 148,995 Current $ 474,000 $ — $ 474,000 134,556 $ 474,000 $ — $ 474,000 148,995 Non-current $ — $ — $ — 3,138 $ — $ — $ — — Grand Total $ 19,948,596 $ 3,662,737 $ 16,285,859 3,788,967 $ 18,276,376 $ 1,580,133 $ 16,696,243 3,483,068
Schedule of contractual principal payments of notes payable	Contractual principal payments due on notes payable are as follows: Year Ending June 30, 2017 2017 $ 17,987,243 2018 $ 1,405,762 2019 $ 555,591 Total $ 19,948,596
Schedule of fair value assumptions for warrants issued in conjunction with notes	The fair value of the warrants issued in conjunction with notes was determined using the Black Scholes Merton Option Pricing Model with the following inputs for the periods ended December 31, 2016. The Company did not issue any warrants in conjunction with notes in the six months ended June 30, 2017. December 31, 2016 Stock price $ 5.00 Exercise price $ 4.50 - 4.70 Term 5 years Risk-free interest rate 1.01 - 1.28% Expected dividend yield — Expected volatility 65.4 - 69.6%

STOCKHOLDERS' DEFICIT (Tables)

STOCKHOLDERS' DEFICIT (Tables)	6 Months Ended
	Jun. 30, 2017
Stockholders' Equity Note [Abstract]
Schedule of outstanding warrants	A summary of outstanding warrants as of June 30, 2017 and December 31, 2016 is presented below: June 30, 2017 December 31, 2016 Warrants outstanding, beginning of period 5,024,668 3,530,918 Granted — 1,493,750 Exercised — — Cancelled, forfeited or expired — — Warrants outstanding, end of period 5,024,668 5,024,668 A summary of outstanding warrants by year issued and exercise price as of Outstanding Exercisable Exercise Price Number of Weighted Weighted Total Weighted At December 31, 2013 $ 3.30 50,000 0.84 $ 3.30 50,000 $ 3.30 $ 3.50 2,225,036 1.20 $ 3.50 2,225,036 $ 3.50 2013 total 2,275,036 2,275,036 At December 31, 2014 $ 3.50 1,145,465 1.23 $ 3.50 1,145,465 $ 3.50 2014 total 1,145,465 1,145,465 At December 31, 2015 $ 4.90 110,417 2.68 $ 4.90 110,417 $ 4.90 2015 total 110,417 110,417 At December 31, 2016 $ 4.50 118,750 4.00 $ 4.50 118,750 $ 4.50 $ 4.70 75,000 3.84 $ 4.70 75,000 $ 4.70 $ 5.00 1,300,000 3.86 $ 5.00 1,300,000 $ 5.00 2016 Total 1,493,750 1,493,750 June 30, 2017 Total 5,024,668 5,024,668
Schedule of outstanding options	Summaries of outstanding options as of June 30, 2017 and December 31, 2016 are presented below. June 30, 2017 December 31, 2016 Number of Options Weighted- Average Exercise Price Number of Options Weighted- Average Exercise Price Options outstanding, beginning of period 6,955,200 $ 4.10 4,753,335 $ 3.60 Granted or deemed issued — $ — 2,596,200 $ 4.97 Exercised — $ — (15,866 ) $ 3.60 Cancelled, forfeited and expired (200,000 ) $ 5.00 (378,469 ) $ 3.91 Options outstanding, end of period 6,755,200 $ 4.07 6,955,200 $ 4.10 Options exercisable, end of period 5,299,628 $ 3.82 4,372,667 $ 3.59 Options available for future grant, end of period 2,244,800 2,044,800

COMMITMENTS AND CONTINGENCIES (

COMMITMENTS AND CONTINGENCIES (Tables)	6 Months Ended
	Jun. 30, 2017
Commitments and Contingencies Disclosure [Abstract]
Schedule of future minimum lease payments	Future minimum lease payments under the agreements are as follows as of June 30, 2017: Year Amount 2017 (six months) $ 273,112 2018 537,600 2019 150,755 2020 2,240 $ 963,707

RELATED PARTY TRANSACTIONS (Tab

RELATED PARTY TRANSACTIONS (Tables)	6 Months Ended
	Jun. 30, 2017
Related Party Transactions [Abstract]
Schedule of outstanding loans from related parties	The following table sets forth information relating to the Company’s loans from related parties outstanding as of June 30, 2017: Class Lender Annual Date Term Principal Highest Amount Amount Conversion Shares Notes payable to related parties—current: Hope Hospice(1) 8 % 1/17/2012 Due on demand $ — $ 200,000 $ 200,000 $ 7,331 $ — — Hope Hospice(1) 8 % 6/14/2012 Due on demand 200,000 200,000 — 8,000 — — Hope Hospice(1) 8 % 6/21/2012 Due on demand 100,000 100,000 — 4,000 — — Hope Hospice(1) 8 % 2/11/2013 Due on demand — 50,000 50,000 1,559 — — Hope Hospice(1) 10 % 1/7/2015 Due on demand 100,000 100,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 2/20/2015 Due on demand 10,000 10,000 — — — — Yutaka Niihara(2)(3) 10 % 5/21/2015 Due on demand — 826,105 94,339 61,829 — — Masaharu & Emiko Osato(3) 11 % 12/29/2015 Due on demand 300,000 300,000 — — — — Lan T. Tran(2) 11 % 2/10/2016 Due on demand 130,510 130,510 — — — — Masaharu & Emiko Osato(3) 11 % 2/25/2016 Due on demand 400,000 400,000 — — — — Hope Hospice(1) 10 % 4/4/2016 Due on demand 50,000 50,000 — — — — Lan T. Tran(2) 10 % 4/29/2016 Due on demand 20,000 20,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 5/5/2016 Due on demand 10,000 10,000 — — — — Hope Hospice(1) 10 % 6/3/2016 Due on demand 250,000 250,000 — — — — Lan T. Tran(2) 10 % 2/9/2017 Due on demand 12,000 12,000 — — — — Sub total $ 1,582,510 $ 2,658,615 $ 344,339 $ 82,719 $ — — Convertible notes payable to related parties—current: Yasushi Nagasaki(2) 10 % 6/29/2012 Due on demand $ 254,000 $ 388,800 $ 134,800 $ 57,886 $ 3.30 80,807 Charles & Kimxa Stark(2) 10 % 10/1/2015 2 years 20,000 20,000 — — 4.50 5,222 Yutaka & Soomi Niihara(2)(3) 10 % 11/16/2015 2 years 200,000 200,000 — — 4.50 51,665 Sub total $ 474,000 $ 608,800 $ 134,800 $ 57,886 — 137,694 Total $ 2,056,510 $ 3,267,415 $ 479,139 $ 140,605 — 137,694 (1) Dr. Niihara, the Chairman and Chief Executive Officer of the Company, is also the Chief Executive Officer of Hope Hospice. (2) Officer and/or Management. (3) Director. The following table sets forth information relating to the Company’s loans from related parties outstanding as of December 31, 2016. Class Lender Annual Date Term Principal Highest Amount Amount Conversion Shares Notes payable to related parties—current: Hope Hospice(1) 8 % 1/17/2012 Due on demand $ 200,000 $ 200,000 $ — $ 20,000 $ — — Hope Hospice(1) 8 % 6/14/2012 Due on demand 200,000 200,000 — 20,000 — — Hope Hospice(1) 8 % 6/21/2012 Due on demand 100,000 100,000 — 10,000 — — Hope Hospice(1) 8 % 2/11/2013 Due on demand 50,000 50,000 — 5,000 — — Hope Hospice(1) 10 % 1/7/2015 Due on demand 100,000 100,000 — — — — Lan T. Tran(2) 10 % 2/9/2015 Due on demand 10,000 10,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 2/20/2015 Due on demand 10,000 10,000 — — — — Yutaka Niihara(2)(3) 10 % 5/21/2015 Due on demand 94,340 826,105 731,765 47,822 — — Masaharu & Emiko Osato(3) 11 % 12/29/2015 Due on demand 300,000 300,000 — — — — Lan T. Tran(2) 11 % 2/10/2016 Due on demand 130,510 130,510 — — — — Hideki & Eiko Uehara(4) 11 % 2/15/2016 Due on demand — 133,333 133,333 12,226 — — Masaharu & Emiko Osato(3) 11 % 2/25/2016 Due on demand 400,000 400,000 — — — — Hope Hospice(1) 10 % 4/4/2016 Due on demand 50,000 50,000 — — — — Willis C. Lee(2)(3) 10 % 4/8/2016 Due on demand — 79,700 79,700 1,288 — — Lan T. Tran(2) 10 % 4/29/2016 Due on demand 20,000 20,000 — — — — IRA Service Trust Co. FBO Peter B. Ludlum(2) 10 % 5/5/2016 Due on demand 10,000 10,000 — — — — Hope Hospice(1) 10 % 6/3/2016 Due on demand 250,000 250,000 — — — — Sub total $ 1,924,850 $ 2,869,648 $ 944,798 $ 116,336 $ — — Convertible notes payable to related parties—current: Yasushi Nagasaki(2) 10 % 6/29/2012 Due on demand $ 254,000 $ 388,800 $ 134,800 $ 27,824 $ 3.30 94,532 Charles & Kimxa Stark(2) 10 % 10/1/2015 2 years 20,000 20,000 — — 4.50 5,002 Yutaka & Soomi Niihara(2)(3) 10 % 11/16/2015 2 years 200,000 200,000 — — 4.50 49,461 Sub total $ 474,000 $ 608,800 $ 134,800 $ 27,824 — 148,995 Total $ 2,398,850 $ 3,478,448 $ 1,079,598 $ 144,160 — 148,995 (1) (2) (3) (4)

GEOGRAPHIC INFORMATION (Tables)

GEOGRAPHIC INFORMATION (Tables)	6 Months Ended
	Jun. 30, 2017
Segment Reporting [Abstract]
Schedule of revenue earned from countries outside of the United States	For the six months ended June 30, 2017 and 2016, the Company earned revenue from countries outside of the United States as set forth in the table below: Country Revenues for the Six Months Ended June 30, 2017 % of Total Revenue for the Six Months Ended June 30, 2017 Revenues for the Six Months Ended June 30, 2016 % of Total Revenue for the Six Months Ended June 30, 2016 Japan $ 70,848 31 % $ 81,095 32 % Taiwan 113,767 50 % 134,267 53 % For the three months ended June 30, 2017 and 2016, the Company earned revenue from countries outside of the United States as set forth in the table below: Country Revenues for the Three Months Ended June 30, 2017 % of Total Revenue for the Three Months Ended June 30, 2017 Revenues for the Three Months Ended June 30, 2016 % of Total Revenue for the Three Months Ended June 30, 2016 Japan $ 42,290 36 % $ 30,021 17 % Taiwan 49,467 42 % 109,056 63 %

SUBSEQUENT EVENTS (Tables)

SUBSEQUENT EVENTS (Tables)	6 Months Ended
	Jun. 30, 2017
Subsequent Events [Abstract]
Schedule of subsequent events	Subsequent to June 30, 2017, the Company issued the following: Note issued after June 30, 2017 Amount Annual Interest Rate Term of Note Conversion Price Convertible note $ 795,028 10.00 % Due on demand $ 3.50 Total $ 795,028 Subsequent to June 30, 2017, the Company issued the following: Common Shares Issued after June 30, 2017 Amount Number of Shares Issued Common shares $ 830,000 103,750 Total $ 830,000 103,750

SUMMARY OF SIGNIFICANT ACCOUN27

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
Accounting Policies [Abstract]
Work-in-process	$ 139,943	$ 34,462
Finished goods	130,868	131,747
Total	$ 270,811	$ 166,209

SUMMARY OF SIGNIFICANT ACCOUN28

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details 1) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
Accounting Policies [Abstract]
Prepaid insurance	$ 126,750	$ 100,060
Other prepaid expenses and current assets	169,889	29,144
Prepaid expenses and other current assets	$ 296,639	$ 129,204

SUMMARY OF SIGNIFICANT ACCOUN29

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details 2) - Warrant Derivative Liabilities - Stock Purchase Warrants [Member] - USD ($)	6 Months Ended	12 Months Ended
	Jun. 30, 2017	Dec. 31, 2016
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance, beginning of period	$ 10,600,000	$ 7,863,000
Change in fair value included in consolidated statements of comprehensive loss	5,662,000	2,737,000
Balance, end of period	$ 16,262,000	$ 10,600,000

SUMMARY OF SIGNIFICANT ACCOUN30

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details 3) - USD ($)	Sep. 11, 2013	Jun. 30, 2017	Dec. 31, 2016
Balance, end of period:
Warrant derivative liabilities		$ 16,262,000	$ 10,600,000
Warrants [Member]
Stock price	$ 3.60	$ 8.20	$ 6
Risk-free interest rate	1.72%	1.27%	1.09%
Expected volatility (peer group)	72.40%	59.20%	68.30%
Expected life (in years)	5 years	1 year 2 months 12 days	1 year 8 months 12 days
Number outstanding	3,320,501	3,320,501	3,320,501
Balance, end of period:
Liability classified warrants	$ 7,541,000
Warrant derivative liabilities		$ 16,262,000	$ 10,600,000

SUMMARY OF SIGNIFICANT ACCOUN31

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details 4)	6 Months Ended
	Jun. 30, 2017USD ($)$ / shares$ / Warrantsshares
Original Loan Principal Amount	$ 17,342,317
Beneficial Conversion Discount Amount	$ 8,589,466
Warrants Issued with Notes (in shares) | shares	75,000
Warrant FMV Discount Amount	$ 161,658
Minimum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 3.05
Maximum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 3.60
2016 Convertible Notes Payable [Member]
Stated Annual Interest Rate	10.00%
Original Loan Principal Amount	$ 10,866,291
Beneficial Conversion Discount Amount	$ 3,196,544
Warrants Issued with Notes (in shares) | shares	75,000
Exercise Price (in dollars per share) | $ / Warrants	4.70
Warrant FMV Discount Amount	$ 161,658
2016 Convertible Notes Payable [Member] | Minimum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 3.50
Effective Interest Rate Including Discounts	14.00%
2016 Convertible Notes Payable [Member] | Maximum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 4.50
Effective Interest Rate Including Discounts	102.00%
2017 Convertible Notes Payable [Member]
Stated Annual Interest Rate	10.00%
Original Loan Principal Amount	$ 6,476,026
Beneficial Conversion Discount Amount	$ 5,392,922
2017 Convertible Notes Payable [Member] | Minimum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 3.50
Effective Interest Rate Including Discounts	10.00%
2017 Convertible Notes Payable [Member] | Maximum [Member]
Conversion Rate (in dollars per share) | $ / shares	$ 7.60
Effective Interest Rate Including Discounts	99.00%

SUMMARY OF SIGNIFICANT ACCOUN32

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative)

Jun. 28, 2017

Oct. 31, 2016USD ($)

Oct. 31, 2016KRW (₩)₩ / shares

Jan. 31, 2009USD ($)shares

Jan. 31, 2009JPY (¥)¥ / sharesshares

Jun. 30, 2017USD ($)$ / sharesshares

Jun. 30, 2016USD ($)

Jun. 13, 2017USD ($)

Jun. 30, 2017USD ($)$ / sharesshares

Jun. 30, 2016USD ($)shares

Jun. 30, 2017₩ / shares

Jun. 30, 2017¥ / shares

Dec. 31, 2016$ / shares

Dec. 31, 2016₩ / shares

Dec. 31, 2016¥ / shares

Advertising costs

$ 8,807

$ 11,500

$ 17,198

$ 15,439

Potentially dilutive securities outstanding | shares

15,568,835

14,410,498

Other current liabilities

36,867,334

$ 36,867,334

Investment capital reserve

31,841,500

31,841,500

Telcon Inc. ("Telcon") [Member]

Gain on derecognition of amounts due to related party

$ 5,000,000

Other current liabilities

31,800,000

31,800,000

2011 Convertible notes payable [Member]

Convertible notes payable, carrying amount

$ 300,000

$ 300,000

Cell Seed Inc [Member]

Shares held as marketable securities | shares

39,250

39,250

Shares originally purchased (in shares) | shares

147,100

147,100

Investment

$ 1,109,819

Investment, closing price | $ / shares

$ 4.73

$ 4.73

$ 4.58

Cell Seed Inc [Member] | Japan, Yen

Investment | ¥

¥ 100,028,000

Investment, in per share | ¥ / shares

¥ 680

Investment, closing price | ¥ / shares

¥ 532

¥ 536

KPM Tech [Member]

Shares held as marketable securities | shares

849,744

849,744

Investment

$ 13,000,000

Investment, closing price | $ / shares

$ 2.30

$ 2.30

12.08

KPM Tech [Member] | Korea (South), Won

Investment | ₩

₩ 14,318,186,400

Investment, in per share | ₩ / shares

₩ 16,850

Investment, closing price | ₩ / shares

₩ 2,625

₩ 14,600

Reverse stock split

1-for-5 reverse stock split

Hanil Vacuum [Member]

Shares held as marketable securities | shares

271,950

271,950

Investment

$ 1,000,000

Investment, closing price | $ / shares

$ 2.62

$ 2.62

$ 2.40

Hanil Vacuum [Member] | Korea (South), Won

Investment | ₩

₩ 1,101,397,500

Investment, in per share | ₩ / shares

₩ 4,050

Investment, closing price | ₩ / shares

₩ 2,985

₩ 2,895

PROPERTY AND EQUIPMENT (Details

PROPERTY AND EQUIPMENT (Details) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
Property and equipment
Property and equipment, gross	$ 359,132	$ 280,974
Less: accumulated depreciation	(236,932)	(227,244)
Property and equipment, net	122,200	53,730
Equipment [Member]
Property and equipment
Property and equipment, gross	223,988	175,410
Leasehold Improvements [Member]
Property and equipment
Property and equipment, gross	61,054	30,804
Furniture and Fixtures [Member]
Property and equipment
Property and equipment, gross	$ 74,090	$ 74,760

PROPERTY AND EQUIPMENT (Detai34

PROPERTY AND EQUIPMENT (Details Narrative) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Property, Plant and Equipment [Abstract]
Depreciation expense	$ 4,049	$ 3,734	$ 9,357	$ 7,402

ACCOUNTS PAYABLE AND ACCRUED 35

ACCOUNTS PAYABLE AND ACCRUED EXPENSES (Details) - USD ($)	Jun. 30, 2017	Dec. 31, 2016
Accounts payable
Clinical and regulatory expenses	$ 430,419	$ 145,239
Legal expenses	49,884	43,700
Consulting fees	196,394	99,800
Accounting fees	83,726	65,267
Selling expenses	20,914	60,724
Investor relations and public relations expenses		19,931
Other vendors	106,983	41,640
Total accounts payable	888,320	476,301
Accrued interest payable, related parties	243,060	274,851
Accrued interest payable	1,253,154	1,441,450
Accrued expenses	4,030,328	716,886
Deferred salary	291,666	291,666
Total accounts payable and accrued expenses	$ 6,706,528	$ 3,201,154

NOTES PAYABLE (Details)

NOTES PAYABLE (Details) - USD ($)	6 Months Ended
	Jun. 30, 2017	Dec. 31, 2016
Principal Outstanding	$ 19,948,596	$ 18,276,376
Discount Amount	3,662,737	1,580,133
Carrying Amount	16,285,859	16,696,243
Notes payable, current	$ 4,376,383	4,094,429
Minimum [Member]
Conversion price	$ 3.05
Maximum [Member]
Conversion price	$ 3.60
2013 Notes payable [Member]
Interest rate	10.00%
Term of Notes	Due on demand
Principal Outstanding	$ 890,000	854,900
Carrying Amount	$ 890,000	854,900
2015 Notes payable [Member]
Interest rate	11.00%
Term of Notes	Due on demand
Principal Outstanding		2,406,194
Carrying Amount		2,406,194
2016 Notes payable [Member]
Interest rate	11.00%
Term of Notes	Due on demand
Principal Outstanding	$ 833,335	833,335
Carrying Amount	$ 833,335	833,335
2017 Notes payable [Member]
Interest rate	11.00%
Term of Notes	Due on demand
Principal Outstanding	$ 2,653,048
Carrying Amount	2,653,048
Notes Payable [Member]
Principal Outstanding	4,376,383	4,094,429
Carrying Amount	4,376,383	4,094,429
Principal Outstanding, current	4,376,383	4,094,429
Notes payable, current	$ 4,376,383	4,094,429
2012 Notes payable - related party [Member]
Interest rate	8.00%
Term of Notes	Due on demand
Principal Outstanding	$ 300,000	500,000
Carrying Amount	$ 300,000	500,000
2013 Notes payable - related party [Member]
Interest rate	8.00%
Term of Notes	Due on demand
Principal Outstanding		50,000
Carrying Amount		50,000
2015 Notes payable - related party [Member]
Term of Notes	Due on demand
Principal Outstanding	$ 410,000	514,340
Carrying Amount	$ 410,000	514,340
2015 Notes payable - related party [Member] | Minimum [Member]
Interest rate	10.00%
2015 Notes payable - related party [Member] | Maximum [Member]
Interest rate	11.00%
2016 Notes payable - related party [Member]
Term of Notes	Due on demand
Principal Outstanding	$ 860,510	860,510
Carrying Amount	$ 860,510	860,510
2016 Notes payable - related party [Member] | Minimum [Member]
Interest rate	10.00%
2016 Notes payable - related party [Member] | Maximum [Member]
Interest rate	11.00%
2017 Notes payable - related party [Member]
Interest rate	10.00%
Term of Notes	Due on demand
Principal Outstanding	$ 12,000
Carrying Amount	12,000
Notes payable - related party [Member]
Principal Outstanding	1,582,510	1,924,850
Carrying Amount	1,582,510	1,924,850
Principal Outstanding, current	1,582,510	1,924,850
Notes payable, current	$ 1,582,510	$ 1,924,850

NOTES PAYABLE (Details 1)

NOTES PAYABLE (Details 1)	6 Months Ended	12 Months Ended
	Jun. 30, 2017USD ($)Number$ / shares	Dec. 31, 2016USD ($)Number
Principal Outstanding	$ 19,948,596	$ 18,276,376
Discount Amount	3,662,737	1,580,133
Total Carrying Amount	$ 16,285,859	$ 16,696,243
Shares Underlying Principal | Number	3,788,967	3,483,068
Convertible notes payable, Current	$ 9,640,669	$ 9,205,007
Convertible notes payable, Non Current	$ 212,297	997,957
Minimum [Member]
Conversion price | $ / shares	$ 3.05
Maximum [Member]
Conversion price | $ / shares	$ 3.60
2011 Convertible notes payable [Member]
Interest rate	10.00%
Term of Notes	5 years
Conversion price | $ / shares	$ 3.05
Principal Outstanding	$ 300,000	300,000
Total Carrying Amount	$ 300,000	$ 300,000
Shares Underlying Principal | Number	98,285	98,285
2014 Convertible notes payable [Member]
Interest rate	10.00%
Term of Notes	Due on demand - 2 years
Term of Notes	2 years
Principal Outstanding	$ 475,909	$ 452,168
Total Carrying Amount	$ 475,909	$ 452,168
Shares Underlying Principal | Number	162,952	152,986
2014 Convertible notes payable [Member] | Minimum [Member]
Conversion price | $ / shares	$ 3.05
2014 Convertible notes payable [Member] | Maximum [Member]
Conversion price | $ / shares	$ 3.60
2015 Convertible notes payable [Member]
Interest rate	10.00%
Term of Notes	2 years
Principal Outstanding	$ 1,543,594	$ 2,904,800
Discount Amount	3,255	104,389
Total Carrying Amount	$ 1,540,339	$ 2,800,411
Shares Underlying Principal | Number	455,630	889,115
2015 Convertible notes payable [Member] | Minimum [Member]
Conversion price | $ / shares	$ 3.50
2015 Convertible notes payable [Member] | Maximum [Member]
Conversion price | $ / shares	$ 3.60
2016 Convertible Notes Payable [Member]
Interest rate	10.00%
Term of Notes	Due on demand -1 year
Term of Notes	1 year
Principal Outstanding	$ 3,720,174	$ 8,126,129
Discount Amount	265,080	1,475,744
Total Carrying Amount	$ 3,455,094	$ 6,650,385
Shares Underlying Principal | Number	945,712	2,193,687
2016 Convertible Notes Payable [Member] | Minimum [Member]
Conversion price | $ / shares	$ 3.50
2016 Convertible Notes Payable [Member] | Maximum [Member]
Conversion price | $ / shares	$ 4.50
2017 Convertible Notes Payable [Member]
Interest rate	10.00%
Term of Notes	Due on demand - 2 years
Term of Notes	2 years
Principal Outstanding	$ 7,476,026
Discount Amount	3,394,402
Total Carrying Amount	$ 4,081,624
Shares Underlying Principal | Number	1,988,694
2017 Convertible Notes Payable [Member] | Minimum [Member]
Conversion price | $ / shares	$ 3.50
2017 Convertible Notes Payable [Member] | Maximum [Member]
Conversion price | $ / shares	$ 7.60
Convertible Notes Payable [Member]
Principal Outstanding	$ 13,515,703	$ 11,783,097
Discount Amount	3,662,737	1,580,133
Total Carrying Amount	$ 9,852,966	$ 10,202,964
Shares Underlying Principal | Number	3,651,273	3,334,073
Principal Outstanding, Current	$ 12,839,151	$ 10,499,303
Principal Outstanding, Non Current	676,552	1,283,794
Discount Amount Current	3,198,482	1,294,296
Discount Amount Non Current	464,255	285,837
Convertible notes payable, Current	9,640,669	9,205,007
Convertible notes payable, Non Current	$ 212,297	$ 997,957
Shares Underlying Principal Current | Number	3,211,532	2,984,161
Shares Underlying Principal Non Current | Number	439,741	349,912
2012 Convertible notes payable - related party [Member]
Interest rate	10.00%
Term of Notes	Due on demand
Conversion price | $ / shares	$ 3.30
Principal Outstanding	$ 254,000	$ 254,000
Total Carrying Amount	$ 254,000	$ 254,000
Shares Underlying Principal | Number	80,807	94,532
2015 Convertible notes payable - related party [Member]
Interest rate	10.00%
Term of Notes	2 years
Conversion price | $ / shares	$ 4.50
Principal Outstanding	$ 220,000	$ 220,000
Total Carrying Amount	$ 220,000	$ 220,000
Shares Underlying Principal | Number	56,887	54,463
Convertible notes payable - related party [Member]
Principal Outstanding	$ 474,000	$ 474,000
Total Carrying Amount	$ 474,000	$ 474,000
Shares Underlying Principal | Number	137,694	148,995
Principal Outstanding, Current	$ 474,000	$ 474,000
Convertible notes payable related parties, Current	$ 474,000	$ 474,000
Shares Underlying Principal Current | Number	134,556	148,995
Shares Underlying Principal Non Current | Number	3,138

NOTES PAYABLE (Details 2)

NOTES PAYABLE (Details 2)	Jun. 30, 2017USD ($)
Contractual principal payments due on loans and notes payable for the year ending
2,017	$ 17,987,243
2,018	1,405,762
2,019	555,591
Total	$ 19,948,596

NOTES PAYABLE (Details 3)

NOTES PAYABLE (Details 3) - Warrants [Member] - $ / shares	Sep. 11, 2013	Jun. 30, 2017	Dec. 31, 2016
Stock price	$ 3.60	$ 8.20	$ 6
Term	5 years	1 year 2 months 12 days	1 year 8 months 12 days
Risk-free interest rate	1.72%	1.27%	1.09%
Expected volatility	72.40%	59.20%	68.30%
Convertible Notes Payable [Member]
Stock price			$ 5
Term			5 years
Convertible Notes Payable [Member] | Minimum [Member]
Exercise Price			$ 4.50
Risk-free interest rate			1.01%
Expected volatility			65.40%
Convertible Notes Payable [Member] | Maximum [Member]
Exercise Price			$ 4.70
Risk-free interest rate			1.28%
Expected volatility			69.60%

NOTES PAYABLE (Details Narrativ

NOTES PAYABLE (Details Narrative) - $ / shares	6 Months Ended
	Jun. 30, 2017	Dec. 31, 2016
Average stated interest rate	10.00%	10.00%
Average effective interest rate	31.00%	27.00%
Percentage of initial public offering price	80.00%
Warrants [Member]
Method of calculation of fair value of warrants	Black-Scholes-Merton option pricing model
Minimum [Member]
Conversion price	$ 3.05
Maximum [Member]
Conversion price	$ 3.60

STOCKHOLDERS' DEFICIT (Details)

STOCKHOLDERS' DEFICIT (Details) - shares	6 Months Ended	12 Months Ended
	Jun. 30, 2017	Dec. 31, 2016
Warrants outstanding summary
Warrants outstanding, ending	5,024,668
Warrants [Member]
Warrants outstanding summary
Warrants outstanding, beginning	5,024,668	3,530,918
Granted		1,493,750
Warrants outstanding, ending	5,024,668	5,024,668

STOCKHOLDERS' DEFICIT (Details

STOCKHOLDERS' DEFICIT (Details 1)	6 Months Ended
	Jun. 30, 2017Numbershares
Outstanding
Warrants outstanding	5,024,668
Exercisable	5,024,668
Warrants Issued in 2013 - Exercise Price $3.30 [Member]
Outstanding
Warrants outstanding	50,000
Weighted Average Remaining Contractual Life (Years)	10 months 2 days
Weighted Average Exercise Price | Number	3.30
Exercisable	50,000
Weighted Average Exercise Price | Number	3.30
Warrants Issued in 2013 - Exercise Price $3.50 [Member]
Outstanding
Warrants outstanding	2,225,036
Weighted Average Remaining Contractual Life (Years)	1 year 2 months 12 days
Weighted Average Exercise Price | Number	3.50
Exercisable	2,225,036
Weighted Average Exercise Price | Number	3.50
Warrants Issued in 2013 [Member]
Outstanding
Warrants outstanding	2,275,036
Exercisable	2,275,036
Warrants Issued in 2014 - Exercise Price $3.50 [Member]
Outstanding
Warrants outstanding	1,145,465
Weighted Average Remaining Contractual Life (Years)	1 year 2 months 22 days
Weighted Average Exercise Price | Number	3.50
Exercisable	1,145,465
Weighted Average Exercise Price | Number	3.50
Warrants Issued in 2014 [Member]
Outstanding
Warrants outstanding	1,145,465
Exercisable	1,145,465
Warrants Issued in 2015 - Exercise Price $4.90 [Member]
Outstanding
Warrants outstanding	110,417
Weighted Average Remaining Contractual Life (Years)	2 years 8 months 4 days
Weighted Average Exercise Price | Number	4.90
Exercisable	110,417
Weighted Average Exercise Price | Number	4.90
Warrants Issued in 2015 [Member]
Outstanding
Warrants outstanding	110,417
Exercisable	110,417
Warrants Issued in 2016 - Exercise Price $4.50 [Member]
Outstanding
Warrants outstanding	118,750
Weighted Average Remaining Contractual Life (Years)	4 years
Weighted Average Exercise Price | Number	4.50
Exercisable	118,750
Weighted Average Exercise Price | Number	4.50
Warrants Issued in 2016 - Exercise Price $4.70 [Member]
Outstanding
Warrants outstanding	75,000
Weighted Average Remaining Contractual Life (Years)	3 years 10 months 2 days
Weighted Average Exercise Price | Number	4.70
Exercisable	75,000
Weighted Average Exercise Price | Number	4.70
Warrants Issued in 2016 - Exercise Price $5.00 [Member]
Outstanding
Warrants outstanding	1,300,000
Weighted Average Remaining Contractual Life (Years)	3 years 10 months 9 days
Weighted Average Exercise Price | Number	5
Exercisable	1,300,000
Weighted Average Exercise Price | Number	5
Warrants Issued in 2016 [Member]
Outstanding
Warrants outstanding	1,493,750
Exercisable	1,493,750

STOCKHOLDERS' DEFICIT (Detail43

STOCKHOLDERS' DEFICIT (Details 2) - 2011 Stock Incentive Option Plan [Member] - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2017	Dec. 31, 2016
Options, Outstanding [Roll Forward]
Options outstanding, beginning	6,955,200	4,753,335
Granted or deemed issued		2,596,200
Exercised		(15,866)
Cancelled, forfeited and expired	(200,000)	(378,469)
Options outstanding, end	6,755,200	6,955,200
Options exercisable	5,299,628	4,372,667
Options available for future grant	2,244,800	2,044,800
Weighted Average Exercise Price [Roll Forward]
Options outstanding, beginning	$ 4.10	$ 3.60
Granted or deemed issued		4.97
Exercised		3.60
Cancelled, forfeited and expired	5	3.91
Options outstanding, end	4.07	4.10
Options exercisable	$ 3.82	$ 3.59

STOCKHOLDERS' DEFICIT (Detail44

STOCKHOLDERS' DEFICIT (Details Narrative) - USD ($)	Sep. 29, 2016	Sep. 12, 2016	Jun. 10, 2014	Sep. 11, 2013	Jun. 30, 2017	Jun. 30, 2016	Dec. 31, 2016	Dec. 31, 2015	Jun. 10, 2015	Sep. 11, 2014
Warrants outstanding					5,024,668
Fair value of outstanding warrants					$ 16,262,000
Issuance of warrants (in shares)					75,000
Share-based compensation					$ 2,803,759	$ 975,205
KPM Tech Co., Ltd [Member] | Letter of Agreement [Member]
Common stock price		$ 15.32
Future capital increases		$ 13,000,000
Hanil Vacuum Co Ltd [Member] | Letter of Agreement [Member]
Common stock price		$ 3.68
Future capital increases		$ 1,000,000
2011 Stock Incentive Option Plan [Member]
Options granted							2,596,200
Exercise price - options					$ 4.07		$ 4.10	$ 3.60
Options outstanding					6,755,200		6,955,200	4,753,335
Total unrecognized compensation cost					$ 5,400,000
Period remaining for recognition of unrecognized compensation cost					1 year 8 months 12 days
2011 Stock Incentive Option Plan [Member] | 2016 Stock Options Tranche 1 [Member]
Options granted					3,000
Exercise price - options					$ 4.70
Vesting percentage					33.00%
2011 Stock Incentive Option Plan [Member] | 2016 Stock Options Tranche 2 [Member]
Options granted					2,296,200
Exercise price - options					$ 5
Vesting percentage					33.00%
2011 Stock Incentive Option Plan [Member] | Stock Options [Member]
Share-based compensation					$ 2,800,000	$ 1,000,000
Warrants [Member]
Warrants outstanding					3,320,501
Share price				$ 3.60	$ 8.20		$ 6
Cashless Exercise Warrants [Member] | Minimum [Member]
Number of shares callable by warrants					1,903,214
Increase in share price					$ 1
Share price					$ 8.20
Cashless Exercise Warrants [Member] | Maximum [Member]
Number of shares callable by warrants					2,057,267
Share price					$ 9.20
Private Placement [Member]
Units issued in offering (in units)				3,020,501
Unit price of offering (in dollars per share)				2.50
Units issued in offering				$ 7,551,253
Warrants issued to broker of the offering				300,000
Exercise price			$ 3.50	$ 3.50
Warrants outstanding										2,225,036
Fair value of outstanding warrants			$ 1,800,000							$ 7,068,000
Number of warrants exercised			1,095,465
Proceeds from exercise of warrants			$ 3,800,000
Issuance of common stock for exercise of warrants			1,095,465
Adjustment ot additional paid-in capital - warrants			$ 1,800,000
Number of registrable securities (in shares)			4,115,966
Private Placement [Member] | Letter of Agreement [Member]
Common stock price		$ 4.50
Reduction in additional paid in capital	$ 720,000
Private Placement [Member] | KPM Tech Co., Ltd [Member] | Letter of Agreement [Member]
Purchase of common stock		$ 17,000,000
Common stock price		$ 4.50
Future capital investment		$ 13,000,000
Number of shares issued	3,777,778
Private Placement [Member] | Hanil Vacuum Co Ltd [Member] | Letter of Agreement [Member]
Purchase of common stock		3,000,000
Common stock price	$ 4.50
Future capital investment		$ 1,000,000
Number of shares issued	666,667
Private Placement [Member] | Replacement Warrants [Member]
Exercise price			$ 3.50
Warrants outstanding									1,095,465
Fair value of outstanding warrants									$ 2,545,000
Issuance of warrants (in shares)			1,095,465
Warrant exercise inducement expense			$ 3,500,000
Private Placement [Member] | Warrants [Member]
Number of registrable securities (in shares)			3,320,501

COMMITMENTS AND CONTINGENCIES45

COMMITMENTS AND CONTINGENCIES (Details)	Jun. 30, 2017USD ($)
Future minimum lease payments
2017 (six months)	$ 273,112
2,018	537,600
2,019	150,755
2,020	2,240
Total	$ 963,707

COMMITMENTS AND CONTINGENCIES46

COMMITMENTS AND CONTINGENCIES (Details Narrative)

Jul. 12, 2017USD ($)Numberkg$ / kg

Jun. 12, 2017USD ($)$ / sharesshares

Jun. 12, 2017KRW (₩)

Oct. 31, 2016USD ($)

Oct. 31, 2016KRW (₩)

Jun. 30, 2017USD ($)$ / sharesshares

Jun. 30, 2016USD ($)

Jun. 30, 2017USD ($)$ / sharesshares

Jun. 30, 2016USD ($)

Jun. 30, 2017₩ / sharesshares

Jun. 12, 2017₩ / sharesshares

Dec. 31, 2016$ / shares

Dec. 31, 2016₩ / shares

Monthly commercialization management fee

$ 4,500

Rent expense

$ 141,790

$ 147,598

$ 293,102

$ 291,963

Telcon Inc. ("Telcon") [Member] | Management Control Acquistion Agreement [Member]

Investment

$ 31,800,000

Investment, closing price | $ / shares

$ 4.79

Ownership interest

10.30%

10.30%

Telcon Inc. ("Telcon") [Member] | Management Control Acquistion Agreement [Member] | Korea (South), Won

Investment | ₩

₩ 36,000,000,000

Shares originally purchased (in shares) | shares

6,643,559

6,643,559

Investment, closing price | ₩ / shares

₩ 5,419

Telcon Inc. ("Telcon") [Member] | API Supply Agreement [Member]

Proceeds from supply agreement

$ 31,800,000

Percentage of right to supply

25.00%

25.00%

Agreement term

15 years

15 years

Telcon Inc. ("Telcon") [Member] | API Supply Agreement [Member] | Korea (South), Won

Proceeds from supply agreement | ₩

₩ 36,000,000,000

Telcon Inc. ("Telcon") [Member] | Revised API Agreement [Member]

Agreement term

5 years

Number of renewals | Number

10

Weight of drug per supply agreement | kg

940,000

Unit price of grade L-glutamine | $ / kg

50

Purchase amount

$ 47,000,000

Telcon Inc. ("Telcon") [Member] | Revised API Agreement [Member] | Minimum [Member]

Yearly purchase commitments

$ 2,500,000

Telcon Inc. ("Telcon") [Member] | Revised API Agreement [Member] | Maximum [Member]

Agreement term

15 years

Yearly purchase commitments

$ 5,000,000

KPM Tech [Member]

Investment

$ 13,000,000

Investment, closing price | $ / shares

$ 2.30

$ 2.30

$ 12.08

Security interests | shares

4,248,720

4,248,720

4,248,720

KPM Tech [Member] | Korea (South), Won

Investment | ₩

₩ 14,318,186,400

Investment, closing price | ₩ / shares

₩ 2,625

₩ 14,600

RELATED PARTY TRANSACTIONS (Det

RELATED PARTY TRANSACTIONS (Details)		6 Months Ended		12 Months Ended
		Jun. 30, 2017USD ($)Number$ / shares		Dec. 31, 2016USD ($)Number$ / shares
Short-term Debt [Line Items]
Principal Amount Outstanding		$ 16,285,859		$ 16,696,243
Shares Underlying Principal | Number		3,788,967		3,483,068
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate		8.00%	[1]	8.00%	[2]
Date of Loan		Jan. 17, 2012	[1]	Jan. 17, 2012	[2]
Term of Loan		Due on demand	[1]	Due on demand	[2]
Principal Amount Outstanding	[2]			$ 200,000
Highest Principal Outstanding		$ 200,000	[1]	200,000	[2]
Amount of Principal Repaid	[1]	200,000
Amount of Interest Paid		$ 7,331	[1]	$ 20,000	[2]
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate		8.00%	[1]	8.00%	[2]
Date of Loan		Jun. 14, 2012	[1]	Jun. 14, 2012	[2]
Term of Loan		Due on demand	[1]	Due on demand	[2]
Principal Amount Outstanding		$ 200,000	[1]	$ 200,000	[2]
Highest Principal Outstanding		200,000	[1]	200,000	[2]
Amount of Interest Paid		$ 8,000	[1]	$ 20,000	[2]
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate		8.00%	[1]	8.00%	[2]
Date of Loan		Jun. 21, 2012	[1]	Jun. 21, 2012	[2]
Term of Loan		Due on demand	[1]	Due on demand	[2]
Principal Amount Outstanding		$ 100,000	[1]	$ 100,000	[2]
Highest Principal Outstanding		100,000	[1]	100,000	[2]
Amount of Interest Paid		$ 4,000	[1]	$ 10,000	[2]
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate		8.00%	[1]	8.00%	[2]
Date of Loan		Feb. 11, 2013	[1]	Feb. 11, 2013	[2]
Term of Loan		Due on demand	[1]	Due on demand	[2]
Principal Amount Outstanding	[2]			$ 50,000
Highest Principal Outstanding		$ 50,000	[1]	50,000	[2]
Amount of Principal Repaid	[1]	50,000
Amount of Interest Paid		$ 1,559	[1]	$ 5,000	[2]
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate		10.00%	[1]	10.00%	[2]
Date of Loan		Jan. 7, 2015	[1]	Jan. 7, 2015	[2]
Term of Loan		Due on demand	[1]	Due on demand	[2]
Principal Amount Outstanding		$ 100,000	[1]	$ 100,000	[2]
Highest Principal Outstanding		$ 100,000	[1]	$ 100,000	[2]
IRA Service Trust Co. FBO Peter B. Ludlum [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%		10.00%
Date of Loan	[3]	Feb. 20, 2015		Feb. 20, 2015
Term of Loan	[3]	Due on demand		Due on demand
Principal Amount Outstanding	[3]	$ 10,000		$ 10,000
Highest Principal Outstanding	[3]	$ 10,000		$ 10,000
Yutaka Niihara [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3],[4]	10.00%		10.00%
Date of Loan	[3],[4]	May 21, 2015		May 21, 2015
Term of Loan	[3],[4]	Due on demand		Due on demand
Principal Amount Outstanding	[3],[4]			$ 94,340
Highest Principal Outstanding	[3],[4]	$ 826,105		826,105
Amount of Principal Repaid	[3],[4]	94,339		731,765
Amount of Interest Paid	[3],[4]	$ 61,829		$ 47,822
Masaharu & Emiko Osato [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[4]	11.00%		11.00%
Date of Loan	[4]	Dec. 29, 2015		Dec. 29, 2015
Term of Loan	[4]	Due on demand		Due on demand
Principal Amount Outstanding	[4]	$ 300,000		$ 300,000
Highest Principal Outstanding	[4]	$ 300,000		$ 300,000
Lan T. Tran [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	11.00%		11.00%
Date of Loan	[3]	Feb. 10, 2016		Feb. 10, 2016
Term of Loan	[3]	Due on demand		Due on demand
Principal Amount Outstanding	[3]	$ 130,510		$ 130,510
Highest Principal Outstanding	[3]	$ 130,510		$ 130,510
Masaharu & Emiko Osato [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[4]	11.00%		11.00%
Date of Loan	[4]	Feb. 25, 2016		Feb. 25, 2016
Term of Loan	[4]	Due on demand		Due on demand
Principal Amount Outstanding	[4]	$ 400,000		$ 400,000
Highest Principal Outstanding	[4]	$ 400,000		$ 400,000
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[1]	10.00%		10.00%
Date of Loan	[1]	Apr. 4, 2016		Apr. 4, 2016
Term of Loan	[1]	Due on demand		Due on demand
Principal Amount Outstanding	[1]	$ 50,000		$ 50,000
Highest Principal Outstanding	[1]	$ 50,000		$ 50,000
Lan T. Tran [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%		10.00%
Date of Loan	[3]	Apr. 29, 2016		Apr. 29, 2016
Term of Loan	[3]	Due on demand		Due on demand
Principal Amount Outstanding	[3]	$ 20,000		$ 20,000
Highest Principal Outstanding	[3]	$ 20,000		$ 20,000
IRA Service Trust Co. FBO Peter B. Ludlum [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%		10.00%
Date of Loan	[3]	May 5, 2016		May 5, 2016
Term of Loan	[3]	Due on demand		Due on demand
Principal Amount Outstanding	[3]	$ 10,000		$ 10,000
Highest Principal Outstanding	[3]	$ 10,000		$ 10,000
Hope Hospice [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[1]	10.00%		10.00%
Date of Loan	[1]	Jun. 3, 2016		Jun. 3, 2016
Term of Loan	[1]	Due on demand		Due on demand
Principal Amount Outstanding	[1]	$ 250,000		$ 250,000
Highest Principal Outstanding	[1]	$ 250,000		250,000
Lan T. Tran [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%
Date of Loan	[3]	Feb. 9, 2017
Term of Loan	[3]	Due on demand
Principal Amount Outstanding	[3]	$ 12,000
Highest Principal Outstanding	[3]	12,000
Notes payable - related party [Member]
Short-term Debt [Line Items]
Principal Amount Outstanding		1,582,510		1,924,850
Highest Principal Outstanding		2,658,615		2,869,648
Amount of Principal Repaid		344,339		944,798
Amount of Interest Paid		$ 82,719		$ 116,336
Yasushi Nagasaki [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%		10.00%
Date of Loan	[3]	Jun. 29, 2012		Jun. 29, 2012
Term of Loan	[3]	Due on demand		Due on demand
Principal Amount Outstanding	[3]	$ 254,000		$ 254,000
Highest Principal Outstanding	[3]	388,800		388,800
Amount of Principal Repaid	[3]	134,800		134,800
Amount of Interest Paid	[3]	$ 57,886		$ 27,824
Conversion price | $ / shares	[3]	$ 3.30		$ 3.30
Shares Underlying Principal | Number	[3]	80,807		94,532
Charles & Kimxa Stark [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]	10.00%		10.00%
Date of Loan	[3]	Oct. 1, 2015		Oct. 1, 2015
Term of Loans	[3]	2 years		2 years
Principal Amount Outstanding	[3]	$ 20,000		$ 20,000
Highest Principal Outstanding	[3]	$ 20,000		$ 20,000
Conversion price | $ / shares	[3]	$ 4.50		$ 4.50
Shares Underlying Principal | Number	[3]	5,222		5,002
Yutaka & Soomi Niihara [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3],[4]	10.00%		10.00%
Date of Loan	[3],[4]	Nov. 16, 2015		Nov. 16, 2015
Term of Loans	[3],[4]	2 years		2 years
Principal Amount Outstanding	[3],[4]	$ 200,000		$ 200,000
Highest Principal Outstanding	[3],[4]	$ 200,000		$ 200,000
Conversion price | $ / shares	[3],[4]	$ 4.50		$ 4.50
Shares Underlying Principal | Number	[3],[4]	51,665		49,461
Convertible notes payable - related party [Member]
Short-term Debt [Line Items]
Principal Amount Outstanding		$ 474,000		$ 474,000
Highest Principal Outstanding		608,800		608,800
Amount of Principal Repaid		134,800		134,800
Amount of Interest Paid		$ 57,886		$ 27,824
Shares Underlying Principal | Number		137,694		148,995
Notes payable and convertible notes payable - related party [Member]
Short-term Debt [Line Items]
Principal Amount Outstanding		$ 2,056,510		$ 2,398,850
Highest Principal Outstanding		3,267,415		3,478,448
Amount of Principal Repaid		479,139		1,079,598
Amount of Interest Paid		$ 140,605		$ 144,160
Shares Underlying Principal | Number		137,694		148,995
Lan T. Tran [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3]			10.00%
Date of Loan	[3]			Feb. 9, 2015
Term of Loan	[3]			Due on demand
Principal Amount Outstanding	[3]			$ 10,000
Highest Principal Outstanding	[3]			$ 10,000
Hideki & Eiko Uehara [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[5]			11.00%
Date of Loan	[5]			Feb. 15, 2016
Term of Loan	[5]			Due on demand
Highest Principal Outstanding	[5]			$ 133,333
Amount of Principal Repaid	[5]			133,333
Amount of Interest Paid	[5]			$ 12,226
Willis C. Lee [Member]
Short-term Debt [Line Items]
Annual Interest Rate	[3],[4]			10.00%
Date of Loan	[3],[4]			Apr. 8, 2016
Term of Loan	[3],[4]			Due on demand
Highest Principal Outstanding	[3],[4]			$ 79,700
Amount of Principal Repaid	[3],[4]			79,700
Amount of Interest Paid	[3],[4]			$ 1,288
[1]	Dr. Niihara, the Chairman and Chief Executive Officer of the Company, is also the Chief Executive Officer of Hope Hospice.
[2]	Dr. Niihara, the Company's Chairman and Chief Executive Officer, is also the CEO of Hope Hospice.
[3]	Officer and/or Management
[4]	Director
[5]	Family of Officer/Director

GEOGRAPHIC INFORMATION (Details

GEOGRAPHIC INFORMATION (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
Japan [Member]
Company revenue earned from countries outside of the U.S.
Revenue	$ 42,290	$ 30,021	$ 70,848	$ 81,095
Percentage of revenue (in percent)	36.00%	17.00%	31.00%	32.00%
Taiwan [Member]
Company revenue earned from countries outside of the U.S.
Revenue	$ 49,467	$ 109,056	$ 113,767	$ 134,267
Percentage of revenue (in percent)	42.00%	63.00%	50.00%	53.00%

SUBSEQUENT EVENTS (Details)

SUBSEQUENT EVENTS (Details) - USD ($)	Jul. 01, 2017	Jun. 30, 2017
Principal Amounts		$ 17,342,317
Subsequent Event [Member]
Principal Amounts	$ 795,028
Subsequent Event [Member] | Convertible Notes Payable [Member]
Principal Amounts	$ 795,028
Annual Interest Rate	10.00%
Term of Notes	Due on demand
Conversion Price	$ 3.50

SUBSEQUENT EVENTS (Details 1)

SUBSEQUENT EVENTS (Details 1) - USD ($)	Jul. 01, 2017	Jun. 30, 2017
Subsequent Event [Line Items]
Common shares		$ 311,600
Common Stock [Member]
Subsequent Event [Line Items]
Common shares		$ 41
Number of Shares Issued		41,000
Subsequent Event [Member]
Subsequent Event [Line Items]
Common shares	$ 830,000
Number of Shares Issued	103,750
Subsequent Event [Member] | Common Stock [Member]
Subsequent Event [Line Items]
Common shares	$ 830,000
Number of Shares Issued	103,750

SUBSEQUENT EVENTS (Details Narr

SUBSEQUENT EVENTS (Details Narrative) - Subsequent Event [Member] - Eton Investment Korea [Member] $ / shares in Units, $ in Millions	Aug. 08, 2017USD ($)$ / shares
Subsequent Event [Line Items]
Proceeds to be received from equity investment from entity	$ 20
Per share investment | $ / shares	$ 12
Purchase commitment of annual production output (percent)	90.00%
Annual revenue guarantee under Plant Agreement	$ 5
Profit margin (percent)	50.00%
Term of Plant Agreement	10 years
Automatic renewal term of Plant Agreement	10 years