POWER OF ATTORNEY
We, the undersigned, under the authority granted to each of us to sign jointly on
behalf of Novartis AG, hereby grant powers to Bartosz Dzikowski, Stephan Sandmeier, Marc
Ceulemans, Anja Konig, Florian Muellershausen, Beat Steffen, and Florent Gros and constitute
and appoint any two of them jointly as our true and lawful attorneys and representatives and to
act on our behalf and to sign filings to be made with the U.S. Securities and Exchange
Commission (the "SEC") relating to the shares of Aerpio Therapeutics, Inc. held by Novartis
Bioventures Ltd, an indirect subsidiary of Novartis AG, as required by the SEC (the "SEC
Filings"), and to undertake and carry out all tasks and formalities on our behalf which may be
required in connection with giving effect to the SEC Filings.
We, the undersigned, undertake to ratify and confirm whatever our true and
lawful attorneys do or purport to do in good faith in the exercise of any power conferred by this
Power of Attorney.
We, the undersigned, declare that a person who deals with our true and lawful
attorneys in good faith may accept a written statement signed by such attorneys to the effect that
this Power of Attorney has not been revoked as conclusive evidence of that fact.
The authority granted by this Power of Attorney shall expire immediately after the
date on which the SEC Filings are no longer required.
IN WITNESS WHEREOF, this Power of Attorney is duly signed on this 12th
day of July 2018.
Novartis AG
By: /s/ Jean-Baptiste Emery
Name: Jean-Baptiste Emery
Title: Authorized Signatory
By: /s/ Felix Eichhorn
Name: Felix Eichhorn
Title: Authorized Signatory
