| Cover | Apr. 25, 2022 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Apr. 25, 2022 |
| Current Fiscal Year End Date | --12-31 |
| Entity File Number | 001-36860 |
| Entity Registrant Name | IOVANCE BIOTHERAPEUTICS, INC. |
| Entity Central Index Key | 0001425205 |
| Entity Tax Identification Number | 75-3254381 |
| Entity Incorporation, State or Country Code | DE |
| Entity Address, Address Line One | 825 Industrial Road |
| Entity Address, Address Line Two | Suite 400 |
| Entity Address, City or Town | San Carlos |
| Entity Address, State or Province | CA |
| Entity Address, Postal Zip Code | 94070 |
| City Area Code | 650 |
| Local Phone Number | 260-7120 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common stock, par value $0.000041666 per share |
| Trading Symbol | IOVA |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
