1 | Names of Reporting Persons
Redmile Group, LLC |
2 | Check the appropriate box if a member of a Group (see
instructions)

(a) 
(b) |
3 | Sec Use Only |
4 | Citizenship or Place of Organization
DELAWARE |
Number of Shares Beneficially Owned by Each
Reporting Person With: | 5 | Sole Voting Power
0.00 | 6 | Shared Voting Power
13,932,449.00 | 7 | Sole Dispositive Power
0.00 | 8 | Shared Dispositive Power
13,932,449.00 |
|
9 | Aggregate Amount Beneficially Owned by Each Reporting
Person
13,932,449.00 |
10 | Check box if the aggregate amount in row (9) excludes
certain shares (See Instructions)
 |
11 | Percent of class represented by amount in row (9)
9.9 % |
12 | Type of Reporting Person (See Instructions)
IA, OO |
Comment for Type of Reporting Person:
Redmile Group, LLC's beneficial ownership of the Issuer's Common Stock, $0.0001 par value ("Common Stock") is comprised of 6,475,317 shares of Common Stock owned by certain private investment vehicles managed by Redmile Group, LLC (the "Redmile Funds"), including Redmile Biopharma Investments III, L.P. ("RBI III"). Subject to the Beneficial Ownership Blocker (as defined below), Redmile Group, LLC may also be deemed to beneficially own 15,659,456 shares of Common Stock issuable upon exercise of certain pre-funded warrants to purchase Common Stock (the "Warrants"). Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrant, and a holder of a Warrant does not have the right to exercise the Warrant held by such holder, to the extent that after giving effect to such issuance after exercise, the holder (together with the holder's affiliates, and any other persons acting as a group together with the holder or any of the holder's affiliates), would beneficially own in excess of 9.99% (the "Beneficial Ownership Limitation") of the number of shares of Common Stock outstanding immediately after giving effect to the issuance of shares of Common Stock issued upon exercise of the Warrant (the "Beneficial Ownership Blocker"). The Beneficial Ownership Limitation may be changed at a holder's election upon 61 days' notice to the Issuer. The 13,932,449 shares of Common Stock reported as beneficially owned by Redmile Group, LLC in this Schedule 13G represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
Percentage based on: (i) 34,958,253 shares of Common Stock outstanding as of November 7, 2024, as reported by the Issuer in its Quarterly Report on Form 10-Q for the quarterly period ended September 30, 2024 filed with the SEC on November 12, 2024 (the "Form 10-Q"), minus (ii) 2,951,425 shares of Common Stock previously outstanding that were exchanged by certain stockholders of the Issuer for Pre-Funded Warrants as of December 23, 2024, as reported by the Issuer in its Form 8-K filed with the Securities and Exchange Commission (the "SEC") on December 23, 2024 (the "Form 8-K"), plus (iii) 100,000,000 shares of Common Stock issued by the Issuer in a private placement, as reported by the Issuer in its Prospectus filed with the SEC on January 28, 2024 (the "Prospectus"), plus (iv) 7,457,132 shares of Common Stock issuable upon exercise of the Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.
1 | Names of Reporting Persons
Jeremy C. Green |
2 | Check the appropriate box if a member of a Group (see
instructions)

(a) 
(b) |
3 | Sec Use Only |
4 | Citizenship or Place of Organization
UNITED KINGDOM |
Number of Shares Beneficially Owned by Each
Reporting Person With: | 5 | Sole Voting Power
0.00 | 6 | Shared Voting Power
13,932,449.00 | 7 | Sole Dispositive Power
0.00 | 8 | Shared Dispositive Power
13,932,449.00 |
|
9 | Aggregate Amount Beneficially Owned by Each Reporting
Person
13,932,449.00 |
10 | Check box if the aggregate amount in row (9) excludes
certain shares (See Instructions)
 |
11 | Percent of class represented by amount in row (9)
9.9 % |
12 | Type of Reporting Person (See Instructions)
HC, IN |
Comment for Type of Reporting Person:
Jeremy C. Green's beneficial ownership of Common Stock is comprised of 6,475,317 shares of Common Stock owned by the Redmile Funds, including RBI III. Subject to the Beneficial Ownership Blocker, Mr. Green may also be deemed to beneficially own 15,659,456 shares of Common Stock issuable upon exercise of the Warrants. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrant, and a holder of a Warrant does not have the right to exercise the Warrant held by such holder, to the extent that the Beneficial Ownership Blocker applies. The 13,932,449 shares of Common Stock reported as beneficially owned by Mr. Green in this Schedule 13G represent 9.99% of the outstanding shares of Common Stock (calculated in accordance with the footnote below). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any.
Percentage based on: (i) 34,958,253 shares of Common Stock outstanding as of November 7, 2024, as reported by the Issuer in the Form 10-Q, minus (ii) 2,951,425 shares of Common Stock previously outstanding that were exchanged by certain stockholders of the Issuer for Pre-Funded Warrants as of December 23, 2024, as reported by the Issuer in the Form 8-K, plus (iii) 100,000,000 shares of Common Stock issued by the Issuer in a private placement as of December 27, 2024, as reported by the Issuer in the Prospectus, plus (iv) 7,457,132 shares of Common Stock issuable upon exercise of the Warrants, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.
1 | Names of Reporting Persons
Redmile Biopharma Investments III, L.P. |
2 | Check the appropriate box if a member of a Group (see
instructions)

(a) 
(b) |
3 | Sec Use Only |
4 | Citizenship or Place of Organization
DELAWARE |
Number of Shares Beneficially Owned by Each
Reporting Person With: | 5 | Sole Voting Power
0.00 | 6 | Shared Voting Power
7,559,323.00 | 7 | Sole Dispositive Power
0.00 | 8 | Shared Dispositive Power
7,559,323.00 |
|
9 | Aggregate Amount Beneficially Owned by Each Reporting
Person
7,559,323.00 |
10 | Check box if the aggregate amount in row (9) excludes
certain shares (See Instructions)
 |
11 | Percent of class represented by amount in row (9)
5.4 % |
12 | Type of Reporting Person (See Instructions)
PN |
Comment for Type of Reporting Person:
RBI III's beneficial ownership of Common Stock is comprised of 102,191 shares of Common Stock directly held by RBI III. Subject to the Beneficial Ownership Blocker, RBI III may also be deemed to beneficially own 15,659,456 shares of Common Stock issuable upon exercise of the Warrants directly held by RBI III. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of any Warrant, and a holder of a Warrant does not have the right to exercise any portion of the Warrant held by such holder, if the Beneficial Ownership Blocker applies. The shares of Common Stock reported as beneficially owned by RBI III in this Schedule 13G represent the shares of Common Stock held directly by RBI III and the 7,457,132 shares of Common Stock that could be issued to RBI III upon exercise of certain of the Warrants directly held by RBI III under the Beneficial Ownership Blocker.
Percentage based on: (i) 34,958,253 shares of Common Stock outstanding as of November 7, 2024, as reported by the Issuer in the Form 10-Q, minus (ii) 2,951,425 shares of Common Stock previously outstanding that were exchanged by certain stockholders of the Issuer for Pre-Funded Warrants as of December 23, 2024, as reported by the Issuer in the Form 8-K, plus (iii) 100,000,000 shares of Common Stock issued by the Issuer in a private placement as of December 27, 2024, as reported by the Issuer in the Prospectus, plus (iv) 7,457,132 shares of Common Stock issuable upon exercise of the Warrants directly held by RBI III, which due to the Beneficial Ownership Limitation is the maximum number of shares that could be issued upon exercise of the Warrants.