BRISTOL-MYERS SQUIBB COMPANY
QUARTERLY TREND ANALYSIS OF REVENUES
(Unaudited, dollars in millions)
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Revenues | 2021 | | 2022 | | % Change | | FX Impact(b) |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | YTD vs. YTD | | Qtr vs. Qtr | | YTD vs. YTD |
United States | $ | 7,010 | | | $ | 7,388 | | | $ | 14,398 | | | $ | 7,296 | | | $ | 21,694 | | | $ | 7,520 | | | $ | 29,214 | | | $ | 7,694 | | | $ | 8,268 | | | $ | 15,962 | | | $ | 7,941 | | | $ | 23,903 | | | | | | | 9% | | 10% | | — | | — |
International | 3,899 | | | 4,124 | | | 8,023 | | | 4,052 | | | 12,075 | | | 4,244 | | | 16,319 | | | 3,727 | | | 3,427 | | | 7,154 | | | 3,062 | | | 10,216 | | | | | | | (24)% | | (15)% | | (10)% | | (9)% |
Other(a) | 164 | | | 191 | | | 355 | | | 276 | | | 631 | | | 221 | | | 852 | | | 227 | | | 192 | | | 419 | | | 215 | | | 634 | | | | | | | (22)% | | — | | — | | — |
Total | $ | 11,073 | | | $ | 11,703 | | | $ | 22,776 | | | $ | 11,624 | | | $ | 34,400 | | | $ | 11,985 | | | $ | 46,385 | | | $ | 11,648 | | | $ | 11,887 | | | $ | 23,535 | | | $ | 11,218 | | | $ | 34,753 | | | | | | | (3)% | | 1% | | (3)% | | (3)% |
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% of Revenues | 2021 | | 2022 | | | | | | | | |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | | | | | | | |
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United States | 63.3 | % | | 63.1 | % | | 63.2 | % | | 62.8 | % | | 63.1 | % | | 62.7 | % | | 63.0 | % | | 66.1 | % | | 69.6 | % | | 67.8 | % | | 70.8 | % | | 68.8 | % | | | | | | | | | | | | |
International | 35.3 | % | | 35.3 | % | | 35.2 | % | | 34.9 | % | | 35.1 | % | | 35.4 | % | | 35.1 | % | | 32.0 | % | | 28.8 | % | | 30.4 | % | | 27.3 | % | | 29.4 | % | | | | | | | | | | | | |
Other(a) | 1.4 | % | | 1.6 | % | | 1.6 | % | | 2.3 | % | | 1.8 | % | | 1.9 | % | | 1.9 | % | | 1.9 | % | | 1.6 | % | | 1.8 | % | | 1.9 | % | | 1.8 | % | | | | | | | | | | | | |
Total | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | 100 | % | | | | | | | | | | | | |
(a) Other revenues include royalties and alliance-related revenues for products not sold by our regional commercial organizations.
(b) Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
BRISTOL-MYERS SQUIBB COMPANY
EARNINGS FROM OPERATIONS
(Unaudited, dollars and shares in millions except per share data) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021 | | 2022 | | % Change |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | YTD vs. YTD |
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Net product sales | $ | 10,798 | | | $ | 11,405 | | | $ | 22,203 | | | $ | 11,243 | | | $ | 33,446 | | | $ | 11,609 | | | $ | 45,055 | | | $ | 11,308 | | | $ | 11,485 | | | $ | 22,793 | | | $ | 10,813 | | | $ | 33,606 | | | | | | | (4)% | | — |
Alliance and other revenues | 275 | | | 298 | | | 573 | | | 381 | | | 954 | | | 376 | | | 1,330 | | | 340 | | | 402 | | | 742 | | | 405 | | | 1,147 | | | | | | | 6% | | 20% |
Total Revenues | 11,073 | | | 11,703 | | | 22,776 | | | 11,624 | | | 34,400 | | | 11,985 | | | 46,385 | | | 11,648 | | | 11,887 | | | 23,535 | | | 11,218 | | | 34,753 | | | | | | | (3)% | | 1% |
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Cost of products sold(a) | 2,841 | | | 2,452 | | | 5,293 | | | 2,291 | | | 7,584 | | | 2,356 | | | 9,940 | | | 2,471 | | | 2,720 | | | 5,191 | | | 2,353 | | | 7,544 | | | | | | | 3% | | (1)% |
Marketing, selling and administrative | 1,666 | | | 1,882 | | | 3,548 | | | 1,788 | | | 5,336 | | | 2,354 | | | 7,690 | | | 1,831 | | | 1,787 | | | 3,618 | | | 1,930 | | | 5,548 | | | | | | | 8% | | 4% |
Research and development(b) | 2,219 | | | 2,478 | | | 4,697 | | | 2,980 | | | 7,677 | | | 2,518 | | | 10,195 | | | 2,260 | | | 2,321 | | | 4,581 | | | 2,418 | | | 6,999 | | | | | | | (19)% | | (9)% |
Acquired IPRD(b) | 6 | | | 793 | | | 799 | | | 271 | | | 1,070 | | | 89 | | | 1,159 | | | 333 | | | 400 | | | 733 | | | 30 | | | 763 | | | | | | | (89)% | | (29)% |
Amortization of acquired intangible assets | 2,513 | | | 2,547 | | | 5,060 | | | 2,546 | | | 7,606 | | | 2,417 | | | 10,023 | | | 2,417 | | | 2,417 | | | 4,834 | | | 2,418 | | | 7,252 | | | | | | | (5)% | | (5)% |
Other (income)/expense, net | (702) | | | (2) | | | (704) | | | (409) | | | (1,113) | | | 393 | | | (720) | | | 649 | | | 284 | | | 933 | | | (140) | | | 793 | | | | | | | (66)% | | ** |
Total Expenses | 8,543 | | | 10,150 | | | 18,693 | | | 9,467 | | | 28,160 | | | 10,127 | | | 38,287 | | | 9,961 | | | 9,929 | | | 19,890 | | | 9,009 | | | 28,899 | | | | | | | (5)% | | 3% |
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Earnings Before Income Taxes | 2,530 | | | 1,553 | | | 4,083 | | | 2,157 | | | 6,240 | | | 1,858 | | | 8,098 | | | 1,687 | | | 1,958 | | | 3,645 | | | 2,209 | | | 5,854 | | | | | | | 2% | | (6)% |
Provision/(Benefit) for Income Taxes | 501 | | | 492 | | | 993 | | | 605 | | | 1,598 | | | (514) | | | 1,084 | | | 404 | | | 529 | | | 933 | | | 601 | | | 1,534 | | | | | | | (1)% | | (4)% |
Net Earnings | 2,029 | | | 1,061 | | | 3,090 | | | 1,552 | | | 4,642 | | | 2,372 | | | 7,014 | | | 1,283 | | | 1,429 | | | 2,712 | | | 1,608 | | | 4,320 | | | | | | | 4% | | (7)% |
Noncontrolling Interest | 8 | | | 6 | | | 14 | | | 6 | | | 20 | | | — | | | 20 | | | 5 | | | 8 | | | 13 | | | 2 | | | 15 | | | | | | | (67)% | | (25)% |
Net Earnings Attributable to BMS | $ | 2,021 | | | $ | 1,055 | | | $ | 3,076 | | | $ | 1,546 | | | $ | 4,622 | | | $ | 2,372 | | | $ | 6,994 | | | $ | 1,278 | | | $ | 1,421 | | | $ | 2,699 | | | $ | 1,606 | | | $ | 4,305 | | | | | | | 4% | | (7)% |
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Diluted Earnings per Common Share* | $ | 0.89 | | | $ | 0.47 | | | $ | 1.36 | | | $ | 0.69 | | | $ | 2.05 | | | $ | 1.07 | | | $ | 3.12 | | | $ | 0.59 | | | $ | 0.66 | | | $ | 1.25 | | | $ | 0.75 | | | $ | 2.00 | | | | | | | 9% | | (2)% |
Weighted-Average Common Shares Outstanding - Diluted | 2,265 | | | 2,252 | | | 2,258 | | | 2,243 | | | 2,253 | | | 2,219 | | | 2,245 | | | 2,164 | | | 2,149 | | | 2,157 | | | 2,148 | | | 2,154 | | | | | | | | | |
Dividends declared per common share | $ | 0.49 | | | $ | 0.49 | | | $ | 0.98 | | | $ | 0.49 | | | $ | 1.47 | | | $ | 0.54 | | | $ | 2.01 | | | $ | 0.54 | | | $ | 0.54 | | | $ | 1.08 | | | $ | 0.54 | | | $ | 1.62 | | | | | | | 10% | | 10% |
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| 2021 | | 2022 | | | | |
% of Total Revenues | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | | | |
Gross Margin | 74.3 | % | | 79.0 | % | | 76.8 | % | | 80.3 | % | | 78.0 | % | | 80.3 | % | | 78.6 | % | | 78.8 | % | | 77.1 | % | | 77.9 | % | | 79.0 | % | | 78.3 | % | | | | | | | | |
Other Ratios | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Effective tax rate | 19.8 | % | | 31.7 | % | | 24.3 | % | | 28.0 | % | | 25.6 | % | | (27.7) | % | | 13.4 | % | | 23.9 | % | | 27.0 | % | | 25.6 | % | | 27.2 | % | | 26.2 | % | | | | | | | | |
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Other (income)/expense, net | 2021 | | 2022 | | % Change |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | YTD vs. YTD |
Interest expense(c) | $ | 353 | | | $ | 330 | | | $ | 683 | | | $ | 328 | | | $ | 1,011 | | | $ | 323 | | | $ | 1,334 | | | $ | 326 | | | $ | 313 | | | $ | 639 | | | $ | 299 | | | $ | 938 | | | | | | | (9)% | | (7)% |
Royalties and licensing income | (367) | | | (405) | | | (772) | | | (425) | | | (1,197) | | | (536) | | | (1,733) | | | (477) | | | (508) | | | (985) | | | (579) | | | (1,564) | | | | | | | 36% | | 31% |
Equity investment losses/(income) | (601) | | | (148) | | | (749) | | | (465) | | | (1,214) | | | 469 | | | (745) | | | 644 | | | 308 | | | 952 | | | 14 | | | 966 | | | | | | | ** | | ** |
Integration expenses | 141 | | | 152 | | | 293 | | | 141 | | | 434 | | | 130 | | | 564 | | | 105 | | | 124 | | | 229 | | | 114 | | | 343 | | | | | | | (19)% | | (21)% |
Contingent consideration | (510) | | | — | | | (510) | | | — | | | (510) | | | (32) | | | (542) | | | 1 | | | — | | | 1 | | | — | | | 1 | | | | | | | N/A | | ** |
Loss/(gain) on debt redemption | 281 | | | — | | | 281 | | | — | | | 281 | | | — | | | 281 | | | 275 | | | (9) | | | 266 | | | — | | | 266 | | | | | | | N/A | | (5)% |
Provision for restructuring | 45 | | | 78 | | | 123 | | | 27 | | | 150 | | | 19 | | | 169 | | | 23 | | | 20 | | | 43 | | | 17 | | | 60 | | | | | | | (37)% | | (60)% |
Litigation and other settlements | (8) | | | 44 | | | 36 | | | 13 | | | 49 | | | 33 | | | 82 | | | (37) | | | 25 | | | (12) | | | 44 | | | 32 | | | | | | | ** | | (35)% |
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Divestiture (gains)/losses | — | | | (11) | | | (11) | | | 2 | | | (9) | | | — | | | (9) | | | (211) | | | — | | | (211) | | | — | | | (211) | | | | | | | (100)% | | ** |
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Other | (36) | | | (42) | | | (78) | | | (30) | | | (108) | | | (13) | | | (121) | | | — | | | 11 | | | 11 | | | (49) | | | (38) | | | | | | | 63% | | (65)% |
Other (income)/expense, net | $ | (702) | | | $ | (2) | | | $ | (704) | | | $ | (409) | | | $ | (1,113) | | | $ | 393 | | | $ | (720) | | | $ | 649 | | | $ | 284 | | | $ | 933 | | | $ | (140) | | | $ | 793 | | | | | | | (66)% | | ** |
* Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
** In excess of +/- 100%.
(a) Excludes amortization of acquired intangible assets.
(b) Research and development charges resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights have been reclassified to the Acquired IPRD line item beginning with the first quarter of 2022. Prior period results have been revised for comparability.
(c) Includes amortization of purchase price adjustments to Celgene debt.
BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF GAAP AND NON-GAAP GROWTH DOLLARS AND PERCENTAGES EXCLUDING FOREIGN EXCHANGE IMPACT
FOR THE PERIOD ENDED SEPTEMBER 30, 2022
(Unaudited, dollars in millions)
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QUARTER-TO-DATE | 2022 | | 2021 | | $ Change | | % Change | | Favorable / (Unfavorable) FX Impact $* | | 2022 Excluding FX | | Favorable / (Unfavorable) FX Impact %* | | % Change Excluding FX |
Revenues | $ | 11,218 | | | $ | 11,624 | | | $ | (406) | | | (3) | % | | $ | (450) | | | $ | 11,668 | | | (3) | % | | — | |
Gross profit | 8,865 | | | 9,333 | | | (468) | | | (5) | % | | N/A | | N/A | | N/A | | N/A |
Gross profit excluding specified items(a) | 8,951 | | | 9,430 | | | (479) | | | (5) | % | | N/A | | N/A | | N/A | | N/A |
Gross profit excluding specified items as a % of revenues | 79.8 | % | | 81.1 | % | | | | | | | | | | | | |
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Marketing, selling and administrative | 1,930 | | | 1,788 | | | 142 | | | 8 | % | | 62 | | | 1,992 | | | 3 | % | | 11 | % |
Marketing, selling and administrative excluding specified items(a) | 1,857 | | | 1,787 | | | 70 | | | 4 | % | | 62 | | | 1,919 | | | 3 | % | | 7 | % |
Marketing, selling and administrative excluding specified items as a % of revenues | 16.6 | % | | 15.4 | % | | | | | | | | | | | | |
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Research and development | 2,418 | | | 2,980 | | | (562) | | | (19) | % | | 33 | | | 2,451 | | | 1 | % | | (18) | % |
Research and development excluding specified items(a) | 2,258 | | | 2,368 | | | (110) | | | (5) | % | | 33 | | | 2,291 | | | 2 | % | | (3) | % |
Research and development excluding specified items as a % of revenues | 20.1 | % | | 20.4 | % | | | | | | | | | | | | |
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YEAR-TO-DATE | 2022 | | 2021 | | $ Change | | % Change | | Favorable / (Unfavorable) FX Impact $* | | 2022 Excluding FX | | Favorable / (Unfavorable) FX Impact %* | | % Change Excluding FX |
Revenues | $ | 34,753 | | | $ | 34,400 | | | $ | 353 | | | 1 | % | | $ | (1,054) | | | $ | 35,807 | | | (3) | % | | 4 | % |
Gross profit | 27,209 | | | 26,816 | | | 393 | | | 1 | % | | N/A | | N/A | | N/A | | N/A |
Gross profit excluding specified items(a) | 27,492 | | | 27,419 | | | 73 | | | — | | | N/A | | N/A | | N/A | | N/A |
Gross profit excluding specified items as a % of revenues | 79.1 | % | | 79.7 | % | | | | | | | | | | | | |
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Marketing, selling and administrative | 5,548 | | | 5,336 | | | 212 | | | 4 | % | | 138 | | | 5,686 | | | 3 | % | | 7 | % |
Marketing, selling and administrative excluding specified items(a) | 5,469 | | | 5,335 | | | 134 | | | 3 | % | | 137 | | | 5,606 | | | 2 | % | | 5 | % |
Marketing, selling and administrative excluding specified items as a % of revenues | 15.7 | % | | 15.5 | % | | | | | | | | | | | | |
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Research and development | 6,999 | | | 7,677 | | | (678) | | | (9) | % | | 74 | | | 7,073 | | | 1 | % | | (8) | % |
Research and development excluding specified items(a) | 6,691 | | | 6,834 | | | (143) | | | (2) | % | | 74 | | | 6,765 | | | 1 | % | | (1) | % |
Research and development excluding specified items as a % of revenues | 19.3 | % | | 19.9 | % | | | | | | | | | | | | |
* Foreign exchange impacts were derived by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
(a) Refer to the Specified Items schedule for further details.
BRISTOL-MYERS SQUIBB COMPANY
WORLDWIDE REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
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| 2021 | | 2022 | | $ Change | | % Change |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | YTD vs. YTD | | Qtr vs. Qtr | | YTD vs. YTD |
In-Line Products | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Eliquis | $ | 2,886 | | | $ | 2,792 | | | $ | 5,678 | | | $ | 2,413 | | | $ | 8,091 | | | $ | 2,671 | | | $ | 10,762 | | | $ | 3,211 | | | $ | 3,235 | | | $ | 6,446 | | | $ | 2,655 | | | $ | 9,101 | | | | | | | $ | 242 | | | $ | 1,010 | | | 10 | % | | 12 | % |
Opdivo | 1,720 | | | 1,910 | | | 3,630 | | | 1,905 | | | 5,535 | | | 1,988 | | | 7,523 | | | 1,923 | | | 2,063 | | | 3,986 | | | 2,047 | | | 6,033 | | | | | | | 142 | | | 498 | | | 7 | % | | 9 | % |
Pomalyst/Imnovid | 773 | | | 854 | | | 1,627 | | | 851 | | | 2,478 | | | 854 | | | 3,332 | | | 826 | | | 908 | | | 1,734 | | | 886 | | | 2,620 | | | | | | | 35 | | | 142 | | | 4 | % | | 6 | % |
Orencia | 758 | | | 814 | | | 1,572 | | | 870 | | | 2,442 | | | 864 | | | 3,306 | | | 792 | | | 876 | | | 1,668 | | | 883 | | | 2,551 | | | | | | | 13 | | | 109 | | | 1 | % | | 4 | % |
Sprycel | 470 | | | 541 | | | 1,011 | | | 551 | | | 1,562 | | | 555 | | | 2,117 | | | 483 | | | 544 | | | 1,027 | | | 560 | | | 1,587 | | | | | | | 9 | | | 25 | | | 2 | % | | 2 | % |
Yervoy | 456 | | | 510 | | | 966 | | | 515 | | | 1,481 | | | 545 | | | 2,026 | | | 515 | | | 525 | | | 1,040 | | | 523 | | | 1,563 | | | | | | | 8 | | | 82 | | | 2 | % | | 6 | % |
Empliciti | 85 | | | 86 | | | 171 | | | 82 | | | 253 | | | 81 | | | 334 | | | 75 | | | 77 | | | 152 | | | 73 | | | 225 | | | | | | | (9) | | | (28) | | | (11) | % | | (11) | % |
Mature and other products(a) | 506 | | | 473 | | | 979 | | | 480 | | | 1,459 | | | 441 | | | 1,900 | | | 462 | | | 435 | | | 897 | | | 441 | | | 1,338 | | | | | | | (39) | | | (121) | | | (8) | % | | (8) | % |
Total In-Line Products | 7,654 | | | 7,980 | | | 15,634 | | | 7,667 | | | 23,301 | | | 7,999 | | | 31,300 | | | 8,287 | | | 8,663 | | | 16,950 | | | 8,068 | | | 25,018 | | | | | | | 401 | | | 1,717 | | | 5 | % | | 7 | % |
New Product Portfolio | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Reblozyl | 112 | | | 128 | | | 240 | | | 160 | | | 400 | | | 151 | | | 551 | | | 156 | | | 172 | | | 328 | | | 190 | | | 518 | | | | | | | 30 | | | 118 | | | 19 | % | | 30 | % |
Abecma | — | | | 24 | | | 24 | | | 71 | | | 95 | | | 69 | | | 164 | | | 67 | | | 89 | | | 156 | | | 107 | | | 263 | | | | | | | 36 | | | 168 | | | 51 | % | | ** |
Zeposia | 18 | | | 28 | | | 46 | | | 40 | | | 86 | | | 48 | | | 134 | | | 36 | | | 66 | | | 102 | | | 69 | | | 171 | | | | | | | 29 | | | 85 | | | 73 | % | | 99 | % |
Breyanzi | — | | | 17 | | | 17 | | | 30 | | | 47 | | | 40 | | | 87 | | | 44 | | | 39 | | | 83 | | | 44 | | | 127 | | | | | | | 14 | | | 80 | | | 47 | % | | ** |
Inrebic | 16 | | | 16 | | | 32 | | | 22 | | | 54 | | | 20 | | | 74 | | | 18 | | | 23 | | | 41 | | | 21 | | | 62 | | | | | | | (1) | | | 8 | | | (5) | % | | 15 | % |
Onureg | 15 | | | 12 | | | 27 | | | 21 | | | 48 | | | 25 | | | 73 | | | 23 | | | 32 | | | 55 | | | 32 | | | 87 | | | | | | | 11 | | | 39 | | | 52 | % | | 81 | % |
Opdualag | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 6 | | | 58 | | | 64 | | | 84 | | | 148 | | | | | | | 84 | | | 148 | | | N/A | | N/A |
Camzyos | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 3 | | | 3 | | | 5 | | | 8 | | | | | | | 5 | | | 8 | | | N/A | | N/A |
Sotyktu | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 1 | | | 1 | | | | | | | 1 | | | 1 | | | N/A | | N/A |
Total New Product Portfolio | 161 | | | 225 | | | 386 | | | 344 | | | 730 | | | 353 | | | 1,083 | | | 350 | | | 482 | | | 832 | | | 553 | | | 1,385 | | | | | | | 209 | | | 655 | | | 61 | % | | 90 | % |
Total In-Line Products and New Product Portfolio | 7,815 | | | 8,205 | | | 16,020 | | | 8,011 | | | 24,031 | | | 8,352 | | | 32,383 | | | 8,637 | | | 9,145 | | | 17,782 | | | 8,621 | | | 26,403 | | | | | | | 610 | | | 2,372 | | | 8 | % | | 10 | % |
Recent LOE Products(b) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Revlimid | $ | 2,944 | | | $ | 3,202 | | | $ | 6,146 | | | $ | 3,347 | | | $ | 9,493 | | | $ | 3,328 | | | $ | 12,821 | | | $ | 2,797 | | | $ | 2,501 | | | $ | 5,298 | | | $ | 2,420 | | | $ | 7,718 | | | | | | | (927) | | | (1,775) | | | (28) | % | | (19) | % |
Abraxane | 314 | | | 296 | | | 610 | | | 266 | | | 876 | | | 305 | | | 1,181 | | | 214 | | | 241 | | | 455 | | | 177 | | | 632 | | | | | | | (89) | | | (244) | | | (33) | % | | (28) | % |
Total Recent LOE Products | 3,258 | | | 3,498 | | | 6,756 | | | 3,613 | | | 10,369 | | | 3,633 | | | 14,002 | | | 3,011 | | | 2,742 | | | 5,753 | | | 2,597 | | | 8,350 | | | | | | | (1,016) | | | (2,019) | | | (28) | % | | (19) | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Total | $ | 11,073 | | | $ | 11,703 | | | $ | 22,776 | | | $ | 11,624 | | | $ | 34,400 | | | $ | 11,985 | | | $ | 46,385 | | | $ | 11,648 | | | $ | 11,887 | | | $ | 23,535 | | | $ | 11,218 | | | $ | 34,753 | | | | | | | (406) | | | 353 | | | (3) | % | | 1 | % |
** In excess of +/- 100%.
(a) Includes over-the-counter (OTC) products, royalty revenue and other mature products.
(b) Recent LOE products includes products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
BRISTOL-MYERS SQUIBB COMPANY
WORLDWIDE REVENUES
FOREIGN EXCHANGE IMPACT (%)
(Unaudited)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
|
| Three Months Ended September 30, 2022 | | Nine Months Ended September 30, 2022 |
| Revenue Change % | | Favorable/ (Unfavorable) FX Impact % | | Revenue Change % Excluding FX | | Revenue Change % | | Favorable/ (Unfavorable) FX Impact % | | Revenue Change % Excluding FX |
In-Line Products | | | | | | | | | | | |
Eliquis | 10% | | (6)% | | 16% | | 12% | | (5)% | | 17% |
Opdivo | 7% | | (6)% | | 13% | | 9% | | (4)% | | 13% |
Pomalyst/Imnovid | 4% | | (4)% | | 8% | | 6% | | (3)% | | 9% |
Orencia | 1% | | (4)% | | 5% | | 4% | | (3)% | | 7% |
Sprycel | 2% | | (5)% | | 7% | | 2% | | (4)% | | 6% |
Yervoy | 2% | | (5)% | | 7% | | 6% | | (4)% | | 10% |
Empliciti | (11)% | | (6)% | | (5)% | | (11)% | | (5)% | | (6)% |
Mature and other products(a) | (8)% | | (4)% | | (4)% | | (8)% | | (3)% | | (5)% |
Total In-Line Products | 5% | | (5)% | | 10% | | 7% | | (4)% | | 11% |
New Product Portfolio | | | | | | | | | | | |
Reblozyl | 19% | | (3)% | | 22% | | 30% | | (2)% | | 32% |
Abecma | 51% | | (8)% | | 59% | | ** | | ** | | ** |
Zeposia | 73% | | (10)% | | 83% | | 99% | | (8)% | | ** |
Breyanzi | 47% | | (3)% | | 50% | | ** | | ** | | ** |
Inrebic | (5)% | | (5)% | | — | | 15% | | (2)% | | 17% |
Onureg | 52% | | (5)% | | 57% | | 81% | | (4)% | | 85% |
Opdualag | N/A | | N/A | | N/A | | N/A | | N/A | | N/A |
Camzyos | N/A | | N/A | | N/A | | N/A | | N/A | | N/A |
Sotyktu | N/A | | N/A | | N/A | | N/A | | N/A | | N/A |
Total New Product Portfolio | 61% | | (5)% | | 66% | | 90% | | (4)% | | 94% |
Total In-Line Products and New Product Portfolio | 8% | | (5)% | | 13% | | 10% | | (4)% | | 14% |
Recent LOE Products(b) | | | | | | | | | | | |
Revlimid | (28)% | | (1)% | | (27)% | | (19)% | | (1)% | | (18)% |
Abraxane | (33)% | | (1)% | | (32)% | | (28)% | | (1)% | | (27)% |
Total Recent LOE Products | (28)% | | (1)% | | (27)% | | (19)% | | (1)% | | (18)% |
| | | | | | | | | | | |
Total | (3)% | | (3)% | | — | | 1% | | (3)% | | 4% |
** In excess of +/- 100%.(a) Includes over-the-counter (OTC) products, royalty revenue and other mature products.
(b) Recent LOE products includes products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
BRISTOL-MYERS SQUIBB COMPANY
U.S. REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021 | | 2022 | | % Change | | | | |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | YTD vs. YTD | | | | |
In-Line Products | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Eliquis | $ | 1,923 | | | $ | 1,722 | | | $ | 3,645 | | | $ | 1,315 | | | $ | 4,960 | | | $ | 1,496 | | | $ | 6,456 | | | $ | 2,147 | | | $ | 2,192 | | | $ | 4,339 | | | $ | 1,729 | | | $ | 6,068 | | | | | | | 31% | | 22% | | | | |
Opdivo | 944 | | | 1,076 | | | 2,020 | | | 1,062 | | | 3,082 | | | 1,120 | | | 4,202 | | | 1,099 | | | 1,205 | | | 2,304 | | | 1,243 | | | 3,547 | | | | | | | 17% | | 15% | | | | |
Pomalyst/Imnovid | 512 | | | 567 | | | 1,079 | | | 586 | | | 1,665 | | | 584 | | | 2,249 | | | 557 | | | 616 | | | 1,173 | | | 640 | | | 1,813 | | | | | | | 9% | | 9% | | | | |
Orencia | 536 | | | 593 | | | 1,129 | | | 644 | | | 1,773 | | | 637 | | | 2,410 | | | 592 | | | 654 | | | 1,246 | | | 682 | | | 1,928 | | | | | | | 6% | | 9% | | | | |
Sprycel | 275 | | | 325 | | | 600 | | | 346 | | | 946 | | | 351 | | | 1,297 | | | 305 | | | 372 | | | 677 | | | 402 | | | 1,079 | | | | | | | 16% | | 14% | | | | |
Yervoy | 294 | | | 328 | | | 622 | | | 313 | | | 935 | | | 330 | | | 1,265 | | | 311 | | | 326 | | | 637 | | | 322 | | | 959 | | | | | | | 3% | | 3% | | | | |
Empliciti | 51 | | | 51 | | | 102 | | | 48 | | | 150 | | | 50 | | | 200 | | | 47 | | | 47 | | | 94 | | | 47 | | | 141 | | | | | | | (2)% | | (6)% | | | | |
Mature and other products(a) | 152 | | | 130 | | | 282 | | | 152 | | | 434 | | | 146 | | | 580 | | | 133 | | | 147 | | | 280 | | | 144 | | | 424 | | | | | | | (5)% | | (2)% | | | | |
Total In-Line Products | 4,687 | | | 4,792 | | | 9,479 | | | 4,466 | | | 13,945 | | | 4,714 | | | 18,659 | | | 5,191 | | | 5,559 | | | 10,750 | | | 5,209 | | | 15,959 | | | | | | | 17% | | 14% | | | | |
New Product Portfolio | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Reblozyl | 98 | | | 110 | | | 208 | | | 147 | | | 355 | | | 130 | | | 485 | | | 134 | | | 144 | | | 278 | | | 156 | | | 434 | | | | | | | 6% | | 22% | | | | |
Abecma | — | | | 24 | | | 24 | | | 67 | | | 91 | | | 67 | | | 158 | | | 56 | | | 72 | | | 128 | | | 75 | | | 203 | | | | | | | 12% | | ** | | | | |
Zeposia | 13 | | | 20 | | | 33 | | | 32 | | | 65 | | | 34 | | | 99 | | | 21 | | | 48 | | | 69 | | | 50 | | | 119 | | | | | | | 56% | | 83% | | | | |
Breyanzi | — | | | 17 | | | 17 | | | 29 | | | 46 | | | 38 | | | 84 | | | 41 | | | 33 | | | 74 | | | 35 | | | 109 | | | | | | | 21% | | ** | | | | |
Inrebic | 15 | | | 15 | | | 30 | | | 20 | | | 50 | | | 17 | | | 67 | | | 15 | | | 20 | | | 35 | | | 17 | | | 52 | | | | | | | (15)% | | 4% | | | | |
Onureg | 14 | | | 12 | | | 26 | | | 21 | | | 47 | | | 22 | | | 69 | | | 19 | | | 25 | | | 44 | | | 24 | | | 68 | | | | | | | 14% | | 45% | | | | |
Opdualag | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 6 | | | 58 | | | 64 | | | 84 | | | 148 | | | | | | | N/A | | N/A | | | | |
Camzyos | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 3 | | | 3 | | | 5 | | | 8 | | | | | | | N/A | | N/A | | | | |
Sotyktu | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 1 | | | 1 | | | | | | | N/A | | N/A | | | | |
Total New Product Portfolio | 140 | | | 198 | | | 338 | | | 316 | | | 654 | | | 308 | | | 962 | | | 292 | | | 403 | | | 695 | | | 447 | | | 1,142 | | | | | | | 41% | | 75% | | | | |
Total In-Line Products and New Product Portfolio | 4,827 | | | 4,990 | | | 9,817 | | | 4,782 | | | 14,599 | | | 5,022 | | | 19,621 | | | 5,483 | | | 5,962 | | | 11,445 | | | 5,656 | | | 17,101 | | | | | | | 18% | | 17% | | | | |
Recent LOE Products(b) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Revlimid | 1,958 | | | 2,164 | | | 4,122 | | | 2,303 | | | 6,425 | | | 2,270 | | | 8,695 | | | 2,038 | | | 2,130 | | | 4,168 | | | 2,170 | | | 6,338 | | | | | | | (6)% | | (1)% | | | | |
Abraxane | 225 | | | 234 | | | 459 | | | 211 | | | 670 | | | 228 | | | 898 | | | 173 | | | 176 | | | 349 | | | 115 | | | 464 | | | | | | | (45)% | | (31)% | | | | |
Total Recent LOE Products | 2,183 | | | 2,398 | | | 4,581 | | | 2,514 | | | 7,095 | | | 2,498 | | | 9,593 | | | 2,211 | | | 2,306 | | | 4,517 | | | 2,285 | | | 6,802 | | | | | | | (9)% | | (4)% | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Total(c) | $ | 7,010 | | | $ | 7,388 | | | $ | 14,398 | | | $ | 7,296 | | | $ | 21,694 | | | $ | 7,520 | | | $ | 29,214 | | | $ | 7,694 | | | $ | 8,268 | | | $ | 15,962 | | | $ | 7,941 | | | $ | 23,903 | | | | | | | 9% | | 10% | | | | |
** In excess of +/- 100%.
(a) Includes OTC products, royalty revenue and other mature products.
(b) Recent LOE products includes products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
(c) Includes Puerto Rico.
BRISTOL-MYERS SQUIBB COMPANY
INTERNATIONAL REVENUES
QUARTERLY REVENUES TREND ANALYSIS
(Unaudited, dollars in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021 | | 2022 | | | | % Change |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | | | | | Qtr vs. Qtr | | YTD vs. YTD |
In-Line Products | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Eliquis | $ | 963 | | | $ | 1,070 | | | $ | 2,033 | | | $ | 1,098 | | | $ | 3,131 | | | $ | 1,175 | | | $ | 4,306 | | | $ | 1,064 | | | $ | 1,043 | | | $ | 2,107 | | | $ | 926 | | | $ | 3,033 | | | | | | | | | | | (16) | % | | (3) | % |
Opdivo | 776 | | | 834 | | | 1,610 | | | 843 | | | 2,453 | | | 868 | | | 3,321 | | | 824 | | | 858 | | | 1,682 | | | 804 | | | 2,486 | | | | | | | | | | | (5) | % | | 1 | % |
Pomalyst/Imnovid | 261 | | | 287 | | | 548 | | | 265 | | | 813 | | | 270 | | | 1,083 | | | 269 | | | 292 | | | 561 | | | 246 | | | 807 | | | | | | | | | | | (7) | % | | (1) | % |
Orencia | 222 | | | 221 | | | 443 | | | 226 | | | 669 | | | 227 | | | 896 | | | 200 | | | 222 | | | 422 | | | 201 | | | 623 | | | | | | | | | | | (11) | % | | (7) | % |
Sprycel | 195 | | | 216 | | | 411 | | | 205 | | | 616 | | | 204 | | | 820 | | | 178 | | | 172 | | | 350 | | | 158 | | | 508 | | | | | | | | | | | (23) | % | | (18) | % |
Yervoy | 162 | | | 182 | | | 344 | | | 202 | | | 546 | | | 215 | | | 761 | | | 204 | | | 199 | | | 403 | | | 201 | | | 604 | | | | | | | | | | | — | | | 11 | % |
Empliciti | 34 | | | 35 | | | 69 | | | 34 | | | 103 | | | 31 | | | 134 | | | 28 | | | 30 | | | 58 | | | 26 | | | 84 | | | | | | | | | | | (24) | % | | (18) | % |
Mature and other products(a) | 354 | | | 343 | | | 697 | | | 328 | | | 1,025 | | | 295 | | | 1,320 | | | 329 | | | 288 | | | 617 | | | 297 | | | 914 | | | | | | | | | | | (9) | % | | (11) | % |
Total In-Line Products | 2,967 | | | 3,188 | | | 6,155 | | | 3,201 | | | 9,356 | | | 3,285 | | | 12,641 | | | 3,096 | | | 3,104 | | | 6,200 | | | 2,859 | | | 9,059 | | | | | | | | | | | (11) | % | | (3) | % |
New Product Portfolio | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Reblozyl | 14 | | | 18 | | | 32 | | | 13 | | | 45 | | | 21 | | | 66 | | | 22 | | | 28 | | | 50 | | | 34 | | | 84 | | | | | | | | | | | ** | | 87 | % |
Abecma | — | | | — | | | — | | | 4 | | | 4 | | | 2 | | | 6 | | | 11 | | | 17 | | | 28 | | | 32 | | | 60 | | | | | | | | | | | ** | | ** |
Zeposia | 5 | | | 8 | | | 13 | | | 8 | | | 21 | | | 14 | | | 35 | | | 15 | | | 18 | | | 33 | | | 19 | | | 52 | | | | | | | | | | | ** | | ** |
Breyanzi | — | | | — | | | — | | | 1 | | | 1 | | | 2 | | | 3 | | | 3 | | | 6 | | | 9 | | | 9 | | | 18 | | | | | | | | | | | ** | | ** |
Inrebic | 1 | | | 1 | | | 2 | | | 2 | | | 4 | | | 3 | | | 7 | | | 3 | | | 3 | | | 6 | | | 4 | | | 10 | | | | | | | | | | | 100 | % | | ** |
Onureg | 1 | | | — | | | 1 | | | — | | | 1 | | | 3 | | | 4 | | | 4 | | | 7 | | | 11 | | | 8 | | | 19 | | | | | | | | | | | N/A | | ** |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Total New Product Portfolio | 21 | | | 27 | | | 48 | | | 28 | | | 76 | | | 45 | | | 121 | | | 58 | | | 79 | | | 137 | | | 106 | | | 243 | | | | | | | | | | | ** | | ** |
Total In-Line Products and New Product Portfolio | 2,988 | | | 3,215 | | | 6,203 | | | 3,229 | | | 9,432 | | | 3,330 | | | 12,762 | | | 3,154 | | | 3,183 | | | 6,337 | | | 2,965 | | | 9,302 | | | | | | | | | | | (8) | % | | (1) | % |
Recent LOE Products(b) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Revlimid | 986 | | | 1,038 | | | 2,024 | | | 1,044 | | | 3,068 | | | 1,058 | | | 4,126 | | | 759 | | | 371 | | | 1,130 | | | 250 | | | 1,380 | | | | | | | | | | | (76) | % | | (55) | % |
Abraxane | 89 | | | 62 | | | 151 | | | 55 | | | 206 | | | 77 | | | 283 | | | 41 | | | 65 | | | 106 | | | 62 | | | 168 | | | | | | | | | | | 13 | % | | (18) | % |
Total Recent LOE Products | 1,075 | | | 1,100 | | | 2,175 | | | 1,099 | | | 3,274 | | | 1,135 | | | 4,409 | | | 800 | | | 436 | | | 1,236 | | | 312 | | | 1,548 | | | | | | | | | | | (72) | % | | (53) | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Total | $ | 4,063 | | | $ | 4,315 | | | $ | 8,378 | | | $ | 4,328 | | | $ | 12,706 | | | $ | 4,465 | | | $ | 17,171 | | | $ | 3,954 | | | $ | 3,619 | | | $ | 7,573 | | | $ | 3,277 | | | $ | 10,850 | | | | | | | | | | | (24) | % | | (15) | % |
** In excess of +/- 100%.
(a) Includes OTC products, royalty revenue and other mature products.
(b) Recent LOE products include products with significant expected decline in revenue from a prior reporting period as a result of a loss of market exclusivity.
BRISTOL-MYERS SQUIBB COMPANY
INTERNATIONAL REVENUES
FOREIGN EXCHANGE IMPACT (%)
(Unaudited)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Three Months Ended September 30, 2022 | | Nine Months Ended September 30, 2022 |
| Revenue Change % | | Favorable/ (Unfavorable) FX Impact % | | Revenue Change % Excluding FX | | Revenue Change % | | Favorable/ (Unfavorable) FX Impact % | | Revenue Change % Excluding FX |
In-Line Products | | | | | | | | | | | |
Eliquis | (16)% | | (14)% | | (2)% | | (3)% | | (11)% | | 8% |
Opdivo | (5)% | | (13)% | | 8% | | 1% | | (10)% | | 11% |
Pomalyst/Imnovid | (7)% | | (13)% | | 6% | | (1)% | | (10)% | | 9% |
Orencia | (11)% | | (13)% | | 2% | | (7)% | | (10)% | | 3% |
Sprycel | (23)% | | (13)% | | (10)% | | (18)% | | (11)% | | (7)% |
Yervoy | — | | (14)% | | 14% | | 11% | | (12)% | | 23% |
Empliciti | (24)% | | (15)% | | (9)% | | (18)% | | (11)% | | (7)% |
Mature and other products(a) | (9)% | | (5)% | | (4)% | | (11)% | | (4)% | | (7)% |
Total In-Line Products | (11)% | | (13)% | | 2% | | (3)% | | (9)% | | 6% |
New Product Portfolio | | | | | | | | | | | |
Reblozyl | ** | | ** | | ** | | 87% | | (20)% | | ** |
Abecma | ** | | ** | | ** | | ** | | ** | | ** |
Zeposia | ** | | ** | | ** | | ** | | ** | | ** |
Breyanzi | ** | | ** | | ** | | ** | | ** | | ** |
Inrebic | 100% | | (50)% | | ** | | ** | | ** | | ** |
Onureg | N/A | | N/A | | N/A | | ** | | ** | | ** |
| | | | | | | | | | | |
| | | | | | | | | | | |
Total New Product Portfolio | ** | | ** | | ** | | ** | | ** | | ** |
Total In-Line Products and New Product Portfolio | (8)% | | (13)% | | 5% | | (1)% | | (10)% | | 9% |
Recent LOE Products(b) | | | | | | | | | | | |
Revlimid | (76)% | | (3)% | | (73)% | | (55)% | | (4)% | | (51)% |
Abraxane | 13% | | (7)% | | 20% | | (18)% | | (4)% | | (14)% |
Total Recent LOE Products | (72)% | | (4)% | | (68)% | | (53)% | | (4)% | | (49)% |
| | | | | | | | | | | |
Total | (24)% | | (10)% | | (14)% | | (15)% | | (9)% | | (6)% |
** In excess of +/- 100%.
(a) Includes over-the-counter (OTC) products, royalty revenue and other mature products.
(b) Recent LOE products includes products with significant expected decline in revenue from a prior reporting period as a result of a loss of exclusivity.
BRISTOL-MYERS SQUIBB COMPANY
SPECIFIED ITEMS
(Unaudited, dollars in millions) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021(a) | | 2022 |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year |
Inventory purchase price accounting adjustments | $ | 79 | | | $ | 88 | | | $ | 167 | | | $ | 97 | | | $ | 264 | | | $ | — | | | $ | 264 | | | $ | 52 | | | $ | 102 | | | $ | 154 | | | $ | 86 | | | $ | 240 | | | | | |
Intangible asset impairment | 315 | | | — | | | 315 | | | — | | | 315 | | | — | | | 315 | | | — | | | — | | | — | | | — | | | — | | | | | |
Site exit and other costs | 23 | | | 1 | | | 24 | | | — | | | 24 | | | — | | | 24 | | | — | | | 43 | | | 43 | | | — | | | 43 | | | | | |
Cost of products sold | 417 | | | 89 | | | 506 | | | 97 | | | 603 | | | — | | | 603 | | | 52 | | | 145 | | | 197 | | | 86 | | | 283 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Employee compensation charges | — | | | 1 | | | 1 | | | — | | | 1 | | | — | | | 1 | | | — | | | — | | | — | | | 73 | | | 73 | | | | | |
Site exit and other costs | (1) | | | — | | | (1) | | | 1 | | | — | | | 2 | | | 2 | | | 2 | | | 4 | | | 6 | | | — | | | 6 | | | | | |
Marketing, selling and administrative | (1) | | | 1 | | | — | | | 1 | | | 1 | | | 2 | | | 3 | | | 2 | | | 4 | | | 6 | | | 73 | | | 79 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
IPRD impairments | — | | | 230 | | | 230 | | | 610 | | | 840 | | | — | | | 840 | | | 40 | | | — | | | 40 | | | 58 | | | 98 | | | | | |
Inventory purchase price accounting adjustments | — | | | — | | | — | | | 1 | | | 1 | | | — | | | 1 | | | 87 | | | 21 | | | 108 | | | 22 | | | 130 | | | | | |
Employee compensation charges | 1 | | | — | | | 1 | | | — | | | 1 | | | — | | | 1 | | | — | | | — | | | — | | | 80 | | | 80 | | | | | |
Site exit and other costs | — | | | — | | | — | | | 1 | | | 1 | | | — | | | 1 | | | — | | | — | | | — | | | — | | | — | | | | | |
Research and development | 1 | | | 230 | | | 231 | | | 612 | | | 843 | | | — | | | 843 | | | 127 | | | 21 | | | 148 | | | 160 | | | 308 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Amortization of acquired intangible assets | 2,513 | | | 2,547 | | | 5,060 | | | 2,546 | | | 7,606 | | | 2,417 | | | 10,023 | | | 2,417 | | | 2,417 | | | 4,834 | | | 2,418 | | | 7,252 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Interest expense(b) | (34) | | | (28) | | | (62) | | | (29) | | | (91) | | | (29) | | | (120) | | | (27) | | | (21) | | | (48) | | | (18) | | | (66) | | | | | |
Equity investment losses/(income) | (608) | | | (154) | | | (762) | | | (465) | | | (1,227) | | | 469 | | | (758) | | | 643 | | | 307 | | | 950 | | | 12 | | | 962 | | | | | |
Integration expenses | 141 | | | 152 | | | 293 | | | 141 | | | 434 | | | 130 | | | 564 | | | 105 | | | 124 | | | 229 | | | 114 | | | 343 | | | | | |
Contingent consideration | (510) | | | — | | | (510) | | | — | | | (510) | | | (32) | | | (542) | | | — | | | — | | | — | | | — | | | — | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Loss on debt redemption | 281 | | | — | | | 281 | | | — | | | 281 | | | — | | | 281 | | | 275 | | | (9) | | | 266 | | | — | | | 266 | | | | | |
Provision for restructuring | 45 | | | 78 | | | 123 | | | 27 | | | 150 | | | 19 | | | 169 | | | 23 | | | 20 | | | 43 | | | 17 | | | 60 | | | | | |
Litigation and other settlements | — | | | — | | | — | | | — | | | — | | | — | | | — | | | (40) | | | — | | | (40) | | | 36 | | | (4) | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Divestiture (gains)/losses | — | | | (11) | | | (11) | | | 2 | | | (9) | | | — | | | (9) | | | (211) | | | — | | | (211) | | | — | | | (211) | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Other | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | 42 | | | 42 | | | 28 | | | 70 | | | | | |
Other (income)/expense, net | (685) | | | 37 | | | (648) | | | (324) | | | (972) | | | 557 | | | (415) | | | 768 | | | 463 | | | 1,231 | | | 189 | | | 1,420 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Increase to pretax income | 2,245 | | | 2,904 | | | 5,149 | | | 2,932 | | | 8,081 | | | 2,976 | | | 11,057 | | | 3,366 | | | 3,050 | | | 6,416 | | | 2,926 | | | 9,342 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Income taxes on items above | (303) | | | (292) | | | (595) | | | (137) | | | (732) | | | (261) | | | (993) | | | (398) | | | (321) | | | (719) | | | (268) | | | (987) | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Income taxes attributed to internal transfer of intangible assets | — | | | — | | | — | | | — | | | — | | | (983) | | | (983) | | | — | | | — | | | — | | | — | | | — | | | | | |
Income taxes | (303) | | | (292) | | | (595) | | | (137) | | | (732) | | | (1,244) | | | (1,976) | | | (398) | | | (321) | | | (719) | | | (268) | | | (987) | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Increase to net earnings | $ | 1,942 | | | $ | 2,612 | | | $ | 4,554 | | | $ | 2,795 | | | $ | 7,349 | | | $ | 1,732 | | | $ | 9,081 | | | $ | 2,968 | | | $ | 2,729 | | | $ | 5,697 | | | $ | 2,658 | | | $ | 8,355 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
(a) Revised to exclude significant R&D charges or other income resulting from up-front and contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights (including related income tax impacts).
(b) Includes amortization of purchase price adjustments to Celgene debt.
BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF CERTAIN GAAP LINE ITEMS TO CERTAIN NON-GAAP LINE ITEMS
(Unaudited, dollars in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021 | | 2022 |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year |
Gross Profit | $ | 8,232 | | | $ | 9,251 | | | $ | 17,483 | | | $ | 9,333 | | | $ | 26,816 | | | $ | 9,629 | | | $ | 36,445 | | | $ | 9,177 | | | $ | 9,167 | | | $ | 18,344 | | | $ | 8,865 | | | $ | 27,209 | | | | | |
Specified items(a) | 417 | | | 89 | | | 506 | | | 97 | | | 603 | | | — | | | 603 | | | 52 | | | 145 | | | 197 | | | 86 | | | 283 | | | | | |
Gross profit excluding specified items | 8,649 | | | 9,340 | | | 17,989 | | | 9,430 | | | 27,419 | | | 9,629 | | | 37,048 | | | 9,229 | | | 9,312 | | | 18,541 | | | 8,951 | | | 27,492 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Marketing, selling and administrative | 1,666 | | | 1,882 | | | 3,548 | | | 1,788 | | | 5,336 | | | 2,354 | | | 7,690 | | | 1,831 | | | 1,787 | | | 3,618 | | | 1,930 | | | 5,548 | | | | | |
Specified items(a) | 1 | | | (1) | | | — | | | (1) | | | (1) | | | (2) | | | (3) | | | (2) | | | (4) | | | (6) | | | (73) | | | (79) | | | | | |
Marketing, selling and administrative excluding specified items | 1,667 | | | 1,881 | | | 3,548 | | | 1,787 | | | 5,335 | | | 2,352 | | | 7,687 | | | 1,829 | | | 1,783 | | | 3,612 | | | 1,857 | | | 5,469 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Research and development | 2,219 | | | 2,478 | | | 4,697 | | | 2,980 | | | 7,677 | | | 2,518 | | | 10,195 | | | 2,260 | | | 2,321 | | | 4,581 | | | 2,418 | | | 6,999 | | | | | |
Specified items(a) | (1) | | | (230) | | | (231) | | | (612) | | | (843) | | | — | | | (843) | | | (127) | | | (21) | | | (148) | | | (160) | | | (308) | | | | | |
Research and development excluding specified items | 2,218 | | | 2,248 | | | 4,466 | | | 2,368 | | | 6,834 | | | 2,518 | | | 9,352 | | | 2,133 | | | 2,300 | | | 4,433 | | | 2,258 | | | 6,691 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Amortization of acquired intangible assets | 2,513 | | | 2,547 | | | 5,060 | | | 2,546 | | | 7,606 | | | 2,417 | | | 10,023 | | | 2,417 | | | 2,417 | | | 4,834 | | | 2,418 | | | 7,252 | | | | | |
Specified items(a) | (2,513) | | | (2,547) | | | (5,060) | | | (2,546) | | | (7,606) | | | (2,417) | | | (10,023) | | | (2,417) | | | (2,417) | | | (4,834) | | | (2,418) | | | (7,252) | | | | | |
Amortization of acquired intangible assets excluding specified items | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Other (income)/expense, net | (702) | | | (2) | | | (704) | | | (409) | | | (1,113) | | | 393 | | | (720) | | | 649 | | | 284 | | | 933 | | | (140) | | | 793 | | | | | |
Specified items(a) | 685 | | | (37) | | | 648 | | | 324 | | | 972 | | | (557) | | | 415 | | | (768) | | | (463) | | | (1,231) | | | (189) | | | (1,420) | | | | | |
Other (income)/expense, net excluding specified items | (17) | | | (39) | | | (56) | | | (85) | | | (141) | | | (164) | | | (305) | | | (119) | | | (179) | | | (298) | | | (329) | | | (627) | | | | | |
(a) Refer to the Specified Items schedule for further details.
BRISTOL-MYERS SQUIBB COMPANY
RECONCILIATION OF GAAP TO NON-GAAP EPS
(Unaudited, dollars and shares in millions except per share data)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| 2021 | | 2022 |
| 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year |
Earnings before income taxes | $ | 2,530 | | | $ | 1,553 | | | $ | 4,083 | | | $ | 2,157 | | | $ | 6,240 | | | $ | 1,858 | | | $ | 8,098 | | | $ | 1,687 | | | $ | 1,958 | | | $ | 3,645 | | | $ | 2,209 | | | $ | 5,854 | | | | | |
Specified items(a) | 2,245 | | | 2,904 | | | 5,149 | | | 2,932 | | | 8,081 | | | 2,976 | | | 11,057 | | | 3,366 | | | 3,050 | | | 6,416 | | | 2,926 | | | 9,342 | | | | | |
Earnings before income taxes excluding specified items | 4,775 | | | 4,457 | | | 9,232 | | | 5,089 | | | 14,321 | | | 4,834 | | | 19,155 | | | 5,053 | | | 5,008 | | | 10,061 | | | 5,135 | | | 15,196 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Provision/(Benefit) for income taxes | 501 | | | 492 | | | 993 | | | 605 | | | 1,598 | | | (514) | | | 1,084 | | | 404 | | | 529 | | | 933 | | | 601 | | | 1,534 | | | | | |
Income taxes on specified items(a) | 303 | | | 292 | | | 595 | | | 137 | | | 732 | | | 261 | | | 993 | | | 398 | | | 321 | | | 719 | | | 268 | | | 987 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Income taxes attributed to internal transfer of intangible assets(a) | — | | | — | | | — | | | — | | | — | | | 983 | | | 983 | | | — | | | — | | | — | | | — | | | — | | | | | |
Provision for income taxes excluding tax on specified items and income taxes attributed to internal transfer of intangible assets | 804 | | | 784 | | | 1,588 | | | 742 | | | 2,330 | | | 730 | | | 3,060 | | | 802 | | | 850 | | | 1,652 | | | 869 | | | 2,521 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Net Earnings attributable to BMS used for Diluted EPS Calculation - GAAP | 2,021 | | | 1,055 | | | 3,076 | | | 1,546 | | | 4,622 | | | 2,372 | | | 6,994 | | | 1,278 | | | 1,421 | | | 2,699 | | | 1,606 | | | 4,305 | | | | | |
Specified items(a) | 1,942 | | | 2,612 | | | 4,554 | | | 2,795 | | | 7,349 | | | 1,732 | | | 9,081 | | | 2,968 | | | 2,729 | | | 5,697 | | | 2,658 | | | 8,355 | | | | | |
Net Earnings attributable to BMS used for Diluted EPS Calculation excluding specified items - Non-GAAP | 3,963 | | | 3,667 | | | 7,630 | | | 4,341 | | | 11,971 | | | 4,104 | | | 16,075 | | | 4,246 | | | 4,150 | | | 8,396 | | | 4,264 | | | 12,660 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Weighted-average Common Shares Outstanding - Diluted-GAAP | 2,265 | | | 2,252 | | | 2,258 | | | 2,243 | | | 2,253 | | | 2,219 | | | 2,245 | | | 2,164 | | | 2,149 | | | 2,157 | | | 2,148 | | | 2,154 | | | | | |
Weighted-average Common Shares Outstanding - Diluted-Non-GAAP | 2,265 | | | 2,252 | | | 2,258 | | | 2,243 | | | 2,253 | | | 2,219 | | | 2,245 | | | 2,164 | | | 2,149 | | | 2,157 | | | 2,148 | | | 2,154 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Diluted Earnings Per Share - GAAP* | $ | 0.89 | | | $ | 0.47 | | | $ | 1.36 | | | $ | 0.69 | | | $ | 2.05 | | | $ | 1.07 | | | $ | 3.12 | | | $ | 0.59 | | | $ | 0.66 | | | $ | 1.25 | | | $ | 0.75 | | | $ | 2.00 | | | | | |
Diluted Earnings Per Share attributable to specified items(a) | 0.85 | | | 1.16 | | | 2.02 | | | 1.24 | | | 3.26 | | | 0.77 | | | 4.04 | | | 1.37 | | | 1.27 | | | 2.64 | | | 1.24 | | | 3.88 | | | | | |
Diluted Earnings Per Share - Non-GAAP* | $ | 1.74 | | | $ | 1.63 | | | $ | 3.38 | | | $ | 1.93 | | | $ | 5.31 | | | $ | 1.84 | | | $ | 7.16 | | | $ | 1.96 | | | $ | 1.93 | | | $ | 3.89 | | | $ | 1.99 | | | $ | 5.88 | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | |
Effective Tax Rate | 19.8 | % | | 31.7 | % | | 24.3 | % | | 28.0 | % | | 25.6 | % | | (27.7) | % | | 13.4 | % | | 23.9 | % | | 27.0 | % | | 25.6 | % | | 27.2 | % | | 26.2 | % | | | | |
Specified items(a) | (3.0) | % | | (14.1) | % | | (7.1) | % | | (13.4) | % | | (9.3) | % | | 42.8 | % | | 2.6 | % | | (8.0) | % | | (10.0) | % | | (9.2) | % | | (10.3) | % | | (9.6) | % | | | | |
Effective Tax Rate excluding specified items | 16.8 | % | | 17.6 | % | | 17.2 | % | | 14.6 | % | | 16.3 | % | | 15.1 | % | | 16.0 | % | | 15.9 | % | | 17.0 | % | | 16.4 | % | | 16.9 | % | | 16.6 | % | | | | |
* Quarterly amounts may not add to the year-to-date amounts, as each period is computed on a discrete basis.
(a) Refer to the Specified Items schedule for further details. Effective tax rate on the Specified Items represents the difference between the GAAP and Non-GAAP effective tax rate.
BRISTOL-MYERS SQUIBB COMPANY
SELECTED BALANCE SHEET INFORMATION
(Unaudited, dollars in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| March 31, 2021 | | June 30, 2021 | | September 30, 2021 | | December 31, 2021 | | March 31, 2022 | | June 30, 2022 | | September 30, 2022 | | December 31, 2022 |
Cash and cash equivalents | $ | 10,982 | | | $ | 11,024 | | | $ | 13,540 | | | $ | 13,979 | | | $ | 12,369 | | | $ | 10,750 | | | $ | 7,734 | | | |
Marketable debt securities - current | 1,948 | | | 1,946 | | | 2,123 | | | 2,987 | | | 2,599 | | | 2,478 | | | 1,293 | | | |
Marketable debt securities - non-current | 288 | | | 143 | | | 46 | | | — | | | — | | | — | | | — | | | |
Cash, cash equivalents and marketable debt securities | 13,218 | | | 13,113 | | | 15,709 | | | 16,966 | | | 14,968 | | | 13,228 | | | 9,027 | | | |
| | | | | | | | | | | | | | | |
Short-term debt obligations | (1,777) | | | (2,655) | | | (5,065) | | | (4,948) | | | (7,522) | | | (4,953) | | | (2,132) | | | |
Long-term debt | (44,505) | | | (42,503) | | | (39,677) | | | (39,605) | | | (37,450) | | | (37,107) | | | (36,966) | | | |
Net debt position | $ | (33,064) | | | $ | (32,045) | | | $ | (29,033) | | | $ | (27,587) | | | $ | (30,004) | | | $ | (28,832) | | | $ | (30,071) | | | |
BRISTOL-MYERS SQUIBB COMPANY
2022 FULL YEAR PROJECTED DILUTED EPS FROM OPERATIONS
EXCLUDING PROJECTED SPECIFIED ITEMS
| | | | | | | | | | | | | | | | | | | | | | | |
| | | Full Year 2022 |
| | | | | | Pre-tax | | Tax | | After-tax |
Projected Diluted Earnings Attributable to Shareholders per Common Share - GAAP(a) | | | | | | | | | | | $2.54 to $2.84 |
Projected Specified Items: | | | | | | | | | | | |
Purchase price accounting adjustments(b) | | | | | | | 4.63 | | | 0.48 | | | 4.15 | |
Acquisition, restructuring and integration expenses(c) | | | | | | | 0.29 | | | 0.06 | | | 0.23 | |
Equity investment losses | | | | | | | 0.45 | | | 0.05 | | | 0.40 | |
Intangible asset impairment | | | | | | | 0.05 | | | 0.01 | | | 0.04 | |
Divestiture gains | | | | | | | (0.10) | | | (0.02) | | | (0.08) | |
Turning Point unvested equity awards | | | | | | | 0.07 | | | 0.01 | | | 0.06 | |
Loss on debt redemption | | | | | | | 0.12 | | | 0.03 | | | 0.09 | |
Other | | | | | | | 0.01 | | | — | | | 0.01 | |
Total | | | | | | | 5.52 | | | 0.62 | | | 4.90 | |
| | | | | | | | | | | |
Projected Diluted Earnings Attributable to Shareholders per Common Share - Non-GAAP(a) | | | | | | | | | | | $7.44 to $7.74 |
(a) Includes net impact of ($0.22) from acquired IPRD and licensing income incurred year-to-date.
(b) Includes amortization of acquired intangible assets, unwind of inventory fair value adjustments and amortization of fair value adjustments of debt assumed from Celgene.
(c) Includes acquisition-related restructuring and integration expenses recognized primarily in Other (income)/expense, net.
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The following table summarizes the company's 2022 financial guidance: |
Line item | | GAAP | | Non-GAAP |
Total net sales | | Approximately $46.0 Billion | | Approximately $46.0 Billion |
Recent LOE products(d) | | Approximately $10.0 billion or double-digit decline | | Approximately $10.0 billion or double-digit decline |
Revlimid | | $9.0-$9.5 billion | | $9.0-$9.5 billion |
In-Line Products & New Product Portfolio | | Approximately $36.0 billion or low double-digit increase | | Approximately $36.0 billion or low double-digit increase |
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Gross margin | | Approximately 78% | | Approximately 79% |
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Operating expenses(e) | | Mid single-digit decline | | Low single-digit decline |
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Effective tax rate | | Approximately 24% | | Approximately 16.5% |
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(d) Recent LOE products include Revlimid and Abraxane.
(e) Operating expenses consist of Marketing, selling and administrative expenses and Research and development expenses, excluding acquired IPRD expenses.
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The GAAP financial results for the full year of 2022 will include specified items, including purchase price accounting adjustments, acquisition and integration expenses, charges associated with restructuring, downsizing and streamlining worldwide operations, impairment of intangible assets, loss on debt redemption, divestiture gains or losses and equity investment (including fair value adjustments attributed to limited partnership equity method investments), Turning Point related charges, among other items. The 2022 financial guidance excludes the impact of any potential future strategic acquisitions and divestitures and any specified items that have not yet been identified and quantified. For a fuller discussion of items that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol Myers Squibb Reports Third Quarter Financial Results for 2022 on October 25, 2022, including “2022 Financial Guidance” and “Use of non-GAAP Financial Information” therein. |
BRISTOL-MYERS SQUIBB COMPANY
USE OF NON-GAAP FINANCIAL INFORMATION
In discussing financial results and guidance, the company refers to financial measures that are not in accordance with U.S. Generally Accepted Accounting Principles (GAAP). The non-GAAP financial measures are provided as supplemental information to the financial measures presented in this supplementary information to the earnings release that are calculated and presented in accordance with GAAP and are presented because management has evaluated the company’s financial results both including and excluding the adjusted items or the effects of foreign currency translation, as applicable, and believes that the non-GAAP financial measures presented portray the results of the company’s baseline performance, supplement or enhance management, analysts and investors overall understanding of the company’s underlying financial performance and trends and facilitate comparisons among current, past and future periods. In addition, non-GAAP gross margin, which is gross profit excluding certain specified items as a percentage of revenues, non-GAAP operating expenses, which is marketing, selling and administrative and research and development expenses excluding certain specified items, non-GAAP marketing, selling and administrative expenses, which is marketing, selling and administrative expense excluding certain specified items, and non-GAAP research and development expenses, which is research and development expenses excluding certain specified items, are relevant and useful for investors because they allow investors to view performance in a manner similar to the method used by our management and make it easier for investors, analysts and peers to compare our operating performance to other companies in our industry and to compare our year-over-year results.
This supplementary information to the earnings release also provides certain revenues and expenses as well as non-GAAP measures excluding the impact of foreign exchange. We calculate foreign exchange impacts by converting our current-period local currency financial results using the prior period average currency rates and comparing these adjusted amounts to our current-period results.
Non-GAAP financial measures such as non-GAAP earnings and related EPS information, are adjusted to exclude certain costs, expenses, gains and losses and other specified items that are evaluated on an individual basis after considering their quantitative and qualitative aspects and typically have one or more of the following characteristics, such as being highly variable, difficult to project, unusual in nature, significant to the results of a particular period or not indicative of past or future operating results. These items are excluded from non-GAAP earnings and related EPS information because the company believes they neither relate to the ordinary course of the company’s business nor reflect the company’s underlying business performance. Similar charges or gains were recognized in prior periods and will likely reoccur in future periods, including amortization of acquired intangible assets, including product rights that generate a significant portion of our ongoing revenue and will recur until the intangible assets are fully amortized, unwind of inventory purchase price adjustments, acquisition and integration expenses, restructuring costs, accelerated depreciation and impairment of property, plant and equipment and intangible assets, divestiture gains or losses, stock compensation resulting from acquisition-related equity awards, pension, legal and other contractual settlement charges, equity investment and contingent value rights fair value adjustments (including fair value adjustments attributed to limited partnership equity method investments) and amortization of fair value adjustments of debt acquired from Celgene in our 2019 exchange offer, among other items. Certain other significant tax items are also excluded such as the impact resulting from internal transfers due to streamlining our legal entity structure subsequent to the Celgene acquisition. Deferred and current income taxes attributed to these items are also adjusted for considering their individual impact to the overall tax expense, deductibility and jurisdictional tax rates.
Beginning with the first quarter of 2022, significant R&D charges or other income resulting from upfront or contingent milestone payments in connection with asset acquisitions or licensing of third-party intellectual property rights are no longer excluded from our non-GAAP financial measures. We made these changes to our presentation of non-GAAP financial measures following comments from and discussions with the U.S. Securities and Exchange Commission. For purposes of comparability, the non-GAAP financial measures for the prior periods have been updated to reflect this change.
Because the non-GAAP financial measures are not calculated in accordance with GAAP, they should not be considered superior to and are not intended to be considered in isolation or as a substitute for the related financial measures presented in the press release that are prepared in accordance with GAAP and may not be the same as or comparable to similarly titled measures presented by other companies due to possible differences in method and in the items being adjusted. We encourage investors to review our financial statements and publicly-filed reports in their entirety and not to rely on any single financial measure.
Reconciliations of the non-GAAP financial measures to the most comparable GAAP measures are provided in the accompanying financial tables and also available on the company's website at www.bms.com Within the accompanying financial tables presented, certain columns and rows may not add due to the use of rounded numbers. Percentages and earnings per share amounts presented are calculated from the underlying amounts.
Also note that a reconciliation of forward-looking, non-GAAP gross margin, non-GAAP operating expenses and non-GAAP tax rate, is not provided because comparable GAAP measures for such measures are not reasonably accessible or reliable due to the inherent difficulty in forecasting and quantifying measures that would be necessary for such reconciliation. Namely, we are not able to reliably predict the impact of specified items or currency exchange rates beyond the next twelve months. In addition, the company believes such a reconciliation would imply a degree of precision and certainty that could be confusing to investors. The variability of the specified items may have a significant and unpredictable impact on our future GAAP results.