Bristol-Myers Squibb S4 Registration of securities issued in business combination transactions | BMY 20 May 20

Exhibit 99.1

LETTER OF TRANSMITTAL

OFFER TO EXCHANGE

Up to $1,243,777,000 aggregate principal amount of 2.875% Senior Notes due 2020, $436,313,000 aggregate principal amount of 3.950% Senior Notes due 2020, $750,000,000 aggregate principal amount of Senior Floating Rate Notes due 2020, $434,815,000 aggregate principal amount of 2.875% Senior Notes due 2021, $464,576,000 aggregate principal amount of 2.250% Senior Notes due 2021, $1,000,000,000 aggregate principal amount of 2.550% Senior Notes due 2021, $861,709,000 aggregate principal amount of 3.250% Senior Notes due 2022, $891,870,000 aggregate principal amount of 3.550% Senior Notes due 2022, $500,000,000 aggregate principal amount of Senior Floating Rate Notes due 2022, $1,500,000,000 aggregate principal amount of 2.600% Senior Notes due 2022, $697,660,000 aggregate principal amount of 2.750% Senior Notes due 2023, $932,101,000 aggregate principal amount of 3.250% Senior Notes due 2023, $636,086,000 aggregate principal amount of 4.000% Senior Notes due 2023, $882,510,000 aggregate principal amount of 3.625% Senior Notes due 2024, $3,250,000,000 aggregate principal amount of 2.900% Senior Notes due 2024, $2,379,532,000 aggregate principal amount of 3.875% Senior Notes due 2025, $2,250,000,000 aggregate principal amount of 3.200% Senior Notes due 2026, $961,528,000 aggregate principal amount of 3.450% Senior Notes due 2027, $1,456,162,000 aggregate principal amount of 3.900% Senior Notes due 2028, $4,000,000,000 aggregate principal amount of 3.400% Senior Notes due 2029, $2,000,000,000 aggregate principal amount of 4.125% Senior Notes due 2039, $245,785,000 aggregate principal amount of 5.700% Senior Notes due 2040, $391,925,000 aggregate principal amount of 5.250% Senior Notes due 2043, $976,477,000 aggregate principal amount of 4.625% Senior Notes due 2044, $1,959,524,000 aggregate principal amount of 5.000% Senior Notes due 2045, $1,236,433,000 aggregate principal amount of 4.350% Senior Notes due 2047, $1,456,840,000 aggregate principal amount of 4.550% Senior Notes due 2048, and $3,750,000,000 aggregate principal amount of 4.250% Senior Notes due 2049

for a like aggregate principal amount of

2.875% Senior Notes due 2020, 3.950% Senior Notes due 2020, Senior Floating Rate Notes due 2020, 2.875% Senior Notes due 2021, 2.250% Senior Notes due 2021, 2.550% Senior Notes due 2021, 3.250% Senior Notes due 2022, 3.550% Senior Notes due 2022, Senior Floating Rate Notes due 2022, 2.600% Senior Notes due 2022, 2.750% Senior Notes due 2023, 3.250% Senior Notes due 2023, 4.000% Senior Notes due 2023, 3.625% Senior Notes due 2024, 2.900% Senior Notes due 2024, 3.875% Senior Notes due 2025, 3.200% Senior Notes due 2026, 3.450% Senior Notes due 2027, 3.900% Senior Notes due 2028, 3.400% Senior Notes due 2029, 4.125% Senior Notes due 2039, 5.700% Senior Notes due 2040, 5.250% Senior Notes due 2043, 4.625% Senior Notes due 2044, 5.000% Senior Notes due 2045, 4.350% Senior Notes due 2047, 4.550% Senior Notes due 2048, and 4.250% Senior Notes due 2049, respectively, in a transaction registered under the Securities Act of 1933, as amended (the “Securities Act”)

PURSUANT TO THE PROSPECTUS
DATED , 2020

THE EXCHANGE OFFERS WILL EXPIRE AT 5:00 P.M., NEW YORK CITY TIME, ON , 2020, SUBJECT TO THE COMPANY’S RIGHT TO EXTEND THE EXPIRATION DATE FOR ANY EXCHANGE OFFER (SUCH DATE AND TIME, AS IT MAY BE EXTENDED, THE “EXPIRATION DATE”). TENDERS MAY BE WITHDRAWN PRIOR TO THE EXPIRATION DATE.

Delivery to:
Global Bondholder Services Corporation (the “Exchange Agent”)

By Registered or Certified Mail, Overnight Delivery:
Global Bondholder Services Corporation
65 Broadway – Suite 404
New York, New York 10006

Attn: Corporate Actions
Tel. No.: (212) 430-3774

For Information Call:
Tel. No.: (212) 430-3774
Toll free: (866) 924-2200

For Facsimile Transmission (for Eligible Institutions only):
(212) 430-3775

Confirm by E-mail:
contact@gbsc-usa.com

DELIVERY OF THIS INSTRUMENT TO AN ADDRESS OTHER THAN AS SET FORTH ABOVE, OR TRANSMISSION OF THIS LETTER OF TRANSMITTAL VIA FACSIMILE OTHER THAN AS SET FORTH ABOVE, WILL NOT CONSTITUTE A VALID DELIVERY OF THIS LETTER OF TRANSMITTAL. THE INSTRUCTIONS ACCOMPANYING THIS LETTER OF TRANSMITTAL SHOULD BE READ CAREFULLY BEFORE THIS LETTER OF TRANSMITTAL IS COMPLETED.

The undersigned acknowledges that he or she has received the prospectus, dated , 2020 (as amended or supplemented, the “Prospectus”), of Bristol-Myers Squibb Company, a Delaware corporation (the “Company”), and this Letter of Transmittal (the “Letter”), which together constitute the Company’s offers (the “Exchange Offers”) to exchange up to $1,243,777,000 aggregate principal amount of 2.875% Senior Notes due 2020, $436,313,000 aggregate principal amount of 3.950% Senior Notes due 2020, $750,000,000 aggregate principal amount of Senior Floating Rate Notes due 2020, $434,815,000 aggregate principal amount of 2.875% Senior Notes due 2021, $464,576,000 aggregate principal amount of 2.250% Senior Notes due 2021, $1,000,000,000 aggregate principal amount of 2.550% Senior Notes due 2021, $861,709,000 aggregate principal amount of 3.250% Senior Notes due 2022, $891,870,000 aggregate principal amount of 3.550% Senior Notes due 2022, $500,000,000 aggregate principal amount of Senior Floating Rate Notes due 2022, $1,500,000,000 aggregate principal amount of 2.600% Senior Notes due 2022, $697,660,000 aggregate principal amount of 2.750% Senior Notes due 2023, $932,101,000 aggregate principal amount of 3.250% Senior Notes due 2023, $636,086,000 aggregate principal amount of 4.000% Senior Notes due 2023, $882,510,000 aggregate principal amount of 3.625% Senior Notes due 2024, $3,250,000,000 aggregate principal amount of 2.900% Senior Notes due 2024, $2,379,532,000 aggregate principal amount of 3.875% Senior Notes due 2025, $2,250,000,000 aggregate principal amount of 3.200% Senior Notes due 2026, $961,528,000 aggregate principal amount of 3.450% Senior Notes due 2027, $1,456,162,000 aggregate principal amount of 3.900% Senior Notes due 2028, $4,000,000,000 aggregate principal amount of 3.400% Senior Notes due 2029, $2,000,000,000 aggregate principal amount of 4.125% Senior Notes due 2039, $245,785,000 aggregate principal amount of 5.700% Senior Notes due 2040, $391,925,000 aggregate principal amount of 5.250% Senior Notes due 2043, $976,477,000 aggregate principal amount of 4.625% Senior Notes due 2044, $1,959,524,000 aggregate principal amount of 5.000% Senior Notes due 2045, $1,236,433,000 aggregate principal amount of 4.350% Senior Notes due 2047, $1,456,840,000 aggregate principal amount of 4.550% Senior Notes due 2048, and $3,750,000,000 aggregate principal amount of

4.250% Senior Notes due 2049 (collectively, the “Original Notes”) for a like aggregate principal amount of 2.875% Senior Notes due 2020, 3.950% Senior Notes due 2020, Senior Floating Rate Notes due 2020, 2.875% Senior Notes due 2021, 2.250% Senior Notes due 2021, 2.550% Senior Notes due 2021, 3.250% Senior Notes due 2022, 3.550% Senior Notes due 2022, Senior Floating Rate Notes due 2022, 2.600% Senior Notes due 2022, 2.750% Senior Notes due 2023, 3.250% Senior Notes due 2023, 4.000% Senior Notes due 2023, 3.625% Senior Notes due 2024, 2.900% Senior Notes due 2024, 3.875% Senior Notes due 2025, 3.200% Senior Notes due 2026, 3.450% Senior Notes due 2027, 3.900% Senior Notes due 2028, 3.400% Senior Notes due 2029, 4.125% Senior Notes due 2039, 5.700% Senior Notes due 2040, 5.250% Senior Notes due 2043, 4.625% Senior Notes due 2044, 5.000% Senior Notes due 2045, 4.350% Senior Notes due 2047, 4.550% Senior Notes due 2048, and 4.250% Senior Notes due 2049, respectively, in a transaction registered under the Securities Act of 1933 (collectively, the “Exchange Notes”). Annex I hereto lists the CUSIP numbers with respect to each series of Original Notes. Capitalized terms used but not defined herein shall have the respective meanings ascribed to them in the Prospectus.

For each Original Note accepted for exchange, the holder of such Original Note will receive an Exchange Note of the same series having a principal amount equal to the principal amount of the surrendered Original Note. Holders of the Exchange Notes on the relevant record date for the first interest payment date following the consummation of the Exchange Offers will receive interest accruing from the most recent date to which interest on the respective Original Notes has been paid. If the regular record date for the first interest payment date would be a date prior to the settlement date of the related Exchange Offer, the record date for such first interest payment date will be the day immediately preceding such first interest payment date.

The terms of the Exchange Notes are substantially identical to the terms of the corresponding series of the Original Notes, except that the Exchange Notes are registered under the Securities Act and the transfer restrictions, registration rights and payment of additional interest in case of non-registration applicable to the Original Notes do not apply to the Exchange Notes.

The Company reserves the right to extend any Exchange Offer at its discretion, in which event the term “Expiration Date” for such Exchange Offer shall mean the latest time and date to which such Exchange Offer is extended. The Company will give oral or written notice of any extension to the Exchange Agent and, as promptly as practicable, to holders of Original Notes.

This Letter is to be completed by a holder of Original Notes either if certificates for such Original Notes are forwarded herewith or if a tender is to be made by book-entry transfer to the Exchange Agent’s account at The Depository Trust Company (“DTC”) in accordance with the procedures set forth in the Prospectus under the caption “The Exchange Offers––Procedures for Tendering” and an Agent’s Message (as defined below) is not delivered.

Tenders of Original Notes by book-entry transfer may also be made by delivering an Agent’s Message in lieu of this Letter. The term “Agent’s Message” means a message, transmitted by DTC to and received by the Exchange Agent and forming a part of a Book-Entry Confirmation (as defined below), which states that DTC has received an express acknowledgment from the tendering participant in its Automated Tender Offer Program (“ATOP”) stating that such participant has received and agrees to be bound by this Letter and that the Company may enforce this Letter against such participant. The term “Book-Entry Confirmation” means a timely confirmation of a book-entry tender of Original Notes into the Exchange Agent’s account at DTC.

Delivery of documents to DTC, the Trustee (as defined in the Prospectus under “Description of Notes”) or the Company does not constitute delivery to the Exchange Agent.

The method of delivery of Original Notes and this Letter and all other required documents to the Exchange Agent is at the election and risk of the holders. Instead of delivery by mail, the Company recommends that holders use an overnight or hand delivery service. In all cases, holders should allow sufficient time to assure delivery to the Exchange Agent before the Expiration Date. No Letter or Original Notes should be sent to the Company.

The undersigned has completed the appropriate boxes below and signed this Letter to indicate the action the undersigned desires to take with respect to the Exchange Offers.

List below the Original Notes to which this Letter relates. If the space provided below is inadequate, the certificate numbers and principal amount of Original Notes should be listed on a separate signed schedule affixed hereto.

All Tendering Holders Complete Box 1:

Series

Certificate
Number(s)*

Aggregate
Principal
Amount
Represented

Principal
Amount
Tendered**

Total

* Need not be completed if Original Notes are being tendered by book-entry transfer.

** Unless otherwise indicated in this column, a holder will be deemed to have tendered ALL of the Original Notes represented by the Original Notes indicated in column 2. See Instruction 2. Original Notes tendered must be in minimum denominations of $2,000 in principal amount and integral multiples of $1,000 in excess thereof. See Instruction 1.

Box 2
Book-Entry Transfer

☐	CHECK HERE IF TENDERED ORIGINAL NOTES ARE BEING DELIVERED BY BOOK-ENTRY TRANSFER MADE TO THE ACCOUNT MAINTAINED BY THE EXCHANGE AGENT AT DTC AND COMPLETE THE FOLLOWING:

Name of Tendering Institution: __________________________________________________________________

Account Number: _____________________________________________________________________________

Transaction Code Number: _____________________________________________________________________

By crediting the Original Notes to the Exchange Agent’s account at DTC using ATOP and by complying with applicable ATOP procedures with respect to the Exchange Offers, including transmitting to the Exchange Agent an Agent’s Message in which the holder of the Original Notes acknowledges and agrees to be bound by the terms of, and makes the representations and warranties contained in, this Letter, the participant in DTC confirms on behalf of itself and the beneficial owners of such Original Notes all provisions of this Letter (including all representations and warranties) applicable to it and such beneficial owner as fully as if it had completed the information required herein and executed and transmitted this Letter to the Exchange Agent.

Box 3
Physical Certificates for Tendered Original Notes

☐	CHECK HERE IF PHYSICAL CERTIFICATES FOR TENDERED ORIGINAL NOTES ARE ENCLOSED HEREWITH.

Box 4
Participating Broker-Dealer

☐	CHECK HERE IF YOU ARE A BROKER-DEALER AND WISH TO RECEIVE TEN (10) ADDITIONAL COPIES OF THE PROSPECTUS AND OF ANY AMENDMENTS OR SUPPLEMENTS THERETO.

Name: _____________________________________________________________________________________

Address: ___________________________________________________________________________________

If the undersigned is not a broker-dealer, the undersigned represents and acknowledges to the Company that (i) it has full power and authority to tender, exchange, sell, assign and transfer the Original Notes it is tendering and that the Company will acquire good, marketable and unencumbered title to the Original Notes, free and clear of all security interests, liens, restrictions, charges and encumbrances or other obligations relating to their sale or transfer and not subject to any adverse claim when the Original Notes are accepted by the Company, (ii) the Exchange Notes acquired in connection with the Exchange Offers are being obtained in the ordinary course of business of the person receiving the Exchange Notes, (iii) it has not engaged in, does not intend to engage in, and has no arrangement or understanding with any person to participate in the distribution, as defined in the Securities Act, of the Exchange Notes it will receive in the Exchange Offers and (iv) it is not an “affiliate” (as defined in Rule 405 under the Securities Act) of the Company.

If the undersigned is a broker-dealer, the undersigned represents and acknowledges to the Company that it is not engaged in, and does not intend to engage in, a distribution of the Exchange Notes, and that it will receive Exchange Notes for its own account in exchange for Original Notes that were acquired by such broker-dealer as a result of market-making activities or other trading activities and that it will be required to acknowledge that it will deliver a prospectus in connection with any resale of such Exchange Notes; however, by so acknowledging and by delivering such a prospectus, the undersigned will not be deemed to admit that it is an “underwriter” within the meaning of the Securities Act (other than in connection with a resale of an unsold allotment from the original sale of the Original Notes).

PLEASE READ THE ACCOMPANYING INSTRUCTIONS CAREFULLY

Ladies and Gentlemen:

Upon the terms and subject to the conditions of the Exchange Offers, the undersigned hereby tenders to the Company the aggregate principal amount of the Original Notes indicated above. Subject to, and effective upon, the acceptance for exchange of the Original Notes tendered hereby, the undersigned hereby sells, assigns and transfers to, or upon the order of, the Company all right, title and interest in and to such Original Notes as are being tendered hereby.

The undersigned hereby irrevocably constitutes and appoints the Exchange Agent as the undersigned’s true and lawful agent and attorney-in-fact with respect to such tendered Original Notes, with full power of substitution, among other things, to cause the Original Notes to be assigned, transferred and exchanged.

The undersigned hereby represents and acknowledges to the Company that (i) it has full power and authority to tender, exchange, sell, assign and transfer the Original Notes it is tendering and that the Company will acquire good, marketable and unencumbered title to the Original Notes, free and clear of all security interests, liens, restrictions, charges and encumbrances or other obligations relating to their sale or transfer and not subject to any adverse claim when the Original Notes are accepted by the Company, (ii) the Exchange Notes acquired in connection with the Exchange Offers are being obtained in the ordinary course of business of the person receiving the Exchange Notes, (iii) it has not engaged in, does not intend to engage in, and has no arrangement or understanding with any person to participate in the distribution, as defined in the Securities Act, of the Exchange Notes it will receive in the Exchange Offers and (iv) it is not an “affiliate” (as defined in Rule 405 under the Securities Act) of the Company.

The undersigned also acknowledges that the Exchange Offers are being made by the Company based upon the Company’s understanding of interpretations by the staff of the SEC as set forth in no-action letters issued to third parties, that the Exchange Notes issued in exchange for the Original Notes pursuant to the Exchange Offers may be offered for resale, resold and otherwise transferred by holders thereof, without compliance with the registration and prospectus delivery provisions of the Securities Act, provided that: (i) such holder is not an “affiliate”, as defined in Rule 405 under the Securities Act, of the Company; (ii) such Exchange Notes received by the undersigned are acquired in the ordinary course of the undersigned’s business; and (iii) such holder is not engaged in, does not intend to engage in, and has no arrangement or understanding with any person to participate in the distribution, as defined in the Securities Act, of the Exchange Notes.

However, the Company has not sought its own no-action letter and therefore the staff of the SEC has not considered the Exchange Offers in the context of a no-action letter. There can be no assurance that the staff of the SEC would make a similar determination with respect to the Exchange Offers as in other circumstances. If a holder of Original Notes is an affiliate of the Company, acquires the Exchange Notes other than in the ordinary course of such holder’s business or is engaged in or intends to engage in a distribution of the Exchange Notes or has any arrangement or understanding with respect to the distribution of the Exchange Notes to be acquired pursuant to the Exchange Offers, such holder could not rely on the applicable interpretations of the staff of the SEC and must comply with the registration and prospectus delivery requirements of the Securities Act in connection with any secondary resale transaction.

The undersigned will, upon request, execute and deliver any additional documents deemed by the Company to be necessary or desirable to complete the sale, assignment and transfer of the Original Notes tendered hereby. All authority conferred or agreed to be conferred in this Letter and every obligation of the undersigned hereunder shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of the undersigned and shall not be affected by, and shall survive, the death or incapacity of the undersigned. This tender may be withdrawn only in accordance with the procedures set forth under the caption “The Exchange Offers—Withdrawal of Tenders” section of the Prospectus.

The Exchange Offers are subject to certain conditions as set forth in the Prospectus under the caption “The Exchange Offers—Conditions to the Exchange Offers”. The undersigned recognizes that as a result of these conditions (which may be waived, in whole or in part, by the Company), as more particularly set forth in the Prospectus, the Company may not be required to exchange any of the Original Notes tendered hereby and, in such event, the Original Notes not exchanged will be returned to the undersigned at the address shown above, promptly following the expiration or termination of the Exchange Offers. In addition, the Company is not required to accept for exchange, or to issue the Exchange Notes in exchange for, any Original Notes and may terminate or amend the Exchange Offers at any time prior to the Expiration Date if any of the conditions set forth under caption “The Exchange Offers—Conditions to the Exchange Offers” in the Prospectus occur.

Unless otherwise indicated in the box entitled “Special Issuance Instructions” below, please deliver the Exchange Notes in the name of the undersigned or, in the case of a book-entry delivery of Original Notes, please credit the Exchange Notes to be issued to the account indicated above maintained at DTC. Similarly, unless otherwise indicated under the box entitled “Special Delivery Instructions” below, please send the Exchange Notes to the undersigned at the address shown above in the box entitled “Description of Original Notes”.

THE UNDERSIGNED, BY COMPLETING THE APPLICABLE BOX OR BOXES ABOVE AND SIGNING THIS LETTER, WILL BE DEEMED TO HAVE TENDERED THE ORIGINAL NOTES AS SET FORTH IN SUCH BOX ABOVE.

	SPECIAL ISSUANCE INSTRUCTIONS (See Instructions 3 and 4)

	To be completed ONLY if certificates for Original Notes not exchanged and/or Exchange Notes are to be issued in the name of and sent to someone other than the person(s) whose signature (s) appear(s) on this Letter, or if Original Notes delivered by book-entry transfer which are not accepted for exchange are to be returned by credit to an account maintained at the Book-Entry Transfer Facility other than the account indicated above.

	Issue Exchange Notes and/or Original Notes to:

	Name(s):
	(Please Type or Print)

	(Please Type or Print)

	Address:


	(Including Zip Code) (Complete IRS Form W-9 or applicable IRS Form W-8)

	☐			Credit unexchanged Original Notes delivered by book-entry transfer to the Book-Entry Transfer Facility account set forth below.


	(Book-Entry Transfer Facility Account Number, if applicable)

	SPECIAL DELIVERY INSTRUCTIONS (See Instructions 3 and 4)

	To be completed ONLY if certificates for Original Notes not exchanged and/or Exchange Notes are to be sent to someone other than the person(s) whose signature(s) appear(s) on this Letter or to such person(s) at an address other than shown in the box entitled “Description of Original Notes” on this Letter above.

	Mail Exchange Notes and/or Original Notes to:

	Name(s):
	(Please Type or Print)


	(Please Type or Print)

	Address:


	(Including Zip Code)

IMPORTANT: THIS LETTER OR A FACSIMILE HEREOF (TOGETHER WITH THE CERTIFICATES FOR ORIGINAL NOTES) OR A BOOK-ENTRY CONFIRMATION AND ALL OTHER REQUIRED DOCUMENTS MUST BE RECEIVED BY THE EXCHANGE AGENT PRIOR TO THE EXPIRATION DATE.

PLEASE READ THIS ENTIRE LETTER CAREFULLY BEFORE COMPLETING ANY BOX ABOVE.

(Signature(s) of Registered Owner(s))

(Date)

Area Code and Telephone Number:

If a holder is tendering any Original Notes, this Letter must be signed by the registered holder(s) as the name(s) appear(s) on the certificate(s) for the Original Notes or on a security position listing or by any person(s) authorized to become registered holder(s) by endorsements and documents transmitted herewith. If signature is by a trustee, executor, administrator, guardian, attorney-in-fact, officer of a corporation or other person acting in a fiduciary or representative capacity, please set forth full title. See Instruction 3.

Name(s):

Title:

(Please Type or Print)

Capacity:

Address:

(Including Zip Code)
SIGNATURE GUARANTEE
(if Required by Instruction 3)

Signature Guaranteed by
an Eligible Institution:

(Authorized Signature)

(Title)

(Name and Firm)

Date:

INSTRUCTIONS

Forming Part of the Terms and Conditions of the

OFFER TO EXCHANGE

for a like aggregate principal amount of

1. Delivery of this Letter and the Original Notes.

This Letter or, in lieu thereof, an Agent’s Message stating that the holder has expressly acknowledged receipt of, and agrees to be bound by and held accountable by, this Letter, is to be completed by or received with respect to holders of Original Notes either if certificates are to be forwarded herewith or if tenders are to be made pursuant to the procedures for delivery by book-entry transfer set forth in the “The Exchange Offers—Procedures for Tendering” section of the Prospectus. Certificates for all physically tendered Original Notes (or Book-Entry Confirmation), as well as a properly completed and duly executed Letter (or facsimile thereof) and any other documents required by this Letter (or, in lieu thereof, an Agent’s Message), must be received by the Exchange Agent at the address set forth herein on or prior to the Expiration Date. Original Notes tendered hereby must be in denominations of $2,000 and any integral multiple of $1,000 in excess thereof.

The method of delivery of this Letter, the Original Notes and all other required documents is at the election and risk of the tendering holders. Instead of delivery by mail, it is recommended that holders use an overnight or hand delivery service. In all cases, sufficient time should be allowed to assure delivery to the Exchange Agent before the Expiration Date. No Letter or Original Notes should be sent to the Company. Holders may request their respective brokers, dealers, commercial banks, trust companies or nominees to effect the tenders for such holders.

See “The Exchange Offers” section of the Prospectus.

2. Partial Tenders (not applicable to holders of Original Notes who tender by book-entry transfer); Withdrawals.

If less than all of the Original Notes evidenced by a submitted certificate are to be tendered, the tendering holder(s) should fill in the aggregate principal amount of Original Notes to be tendered in the box “Description of Original Notes—Principal Amount Tendered.” A newly reissued certificate for the Original Notes submitted but not tendered will be sent to such holder as soon as practicable after the Expiration Date. All of the Original Notes delivered to the Exchange Agent will be deemed to have been tendered unless otherwise clearly indicated.

A tender pursuant to the Exchange Offers may be withdrawn at any time prior to the Expiration Date. To be effective, a written or facsimile transmission notice of withdrawal must: (i) be received by the Exchange Agent prior to the Expiration Date; (ii) specify the name of the person who deposited the Original Notes to be withdrawn; (iii) identify the Original Notes to be withdrawn (including the certificate number(s), if any, and principal amount of such Original Notes); (iv) be signed by the depositor in the same manner as the original signature on this Letter by which such Original Notes were tendered (including any required signature guarantees) or be accompanied by documents of transfer sufficient to have the trustee register the transfer of such Original Notes into the name of the person withdrawing the tender; and (v) specify the name in which any such Original Notes are to be registered, if different from that of the depositor. The Exchange Agent will return the properly withdrawn Original Notes promptly following receipt of notice of withdrawal. If Original Notes have been tendered pursuant to the procedure for book-entry transfer, any notice of withdrawal must specify the name and number of the account at the Book-Entry Transfer Facility to be credited with the withdrawn Original Notes or otherwise comply with the Book-Entry Transfer Facility’s procedures. All questions as to the validity of notices of withdrawal, including time of receipt, will be determined by the Company, in its sole discretion, and such determination will be final and binding on all parties.

3. Signatures on this Letter, Bond Powers and Endorsements; Guarantee of Signatures.

If this Letter is signed by the registered holder(s) of the Original Notes tendered hereby, the signature must correspond exactly with the name as written on the face of the certificates or on DTC’s security position listing without alteration, enlargement or any change whatsoever.

If any tendered Original Notes are owned of record by two or more joint owners, all such owners must sign this Letter.

If any tendered Original Notes are registered in different names on several certificates, it will be necessary to complete, sign and submit as many separate copies of this Letter as there are different registrations of certificates.

When this Letter is signed by the registered holder(s) (which term, for the purposes described herein, shall include the Book-Entry Transfer Facility whose name appears on a security listing as the owner of the Original Notes) of the Original Notes specified herein and tendered hereby, no endorsements of certificates or separate bond powers are required. If, however, the Exchange Notes are to be issued to a person other than the registered holder(s), then endorsements of any certificates transmitted hereby or separate bond powers are required. Signatures on such certificates must be guaranteed by an Eligible Institution (as defined below).

If this Letter is signed by a person other than the registered holder(s) of any Original Notes specified therein, such certificate(s) must be endorsed by such registered holder(s) or accompanied by separate written instruments of transfer or endorsed in blank by such registered holder(s) in form satisfactory to the Company and duly executed by the registered holder, in either case signed exactly as such registered holder’s or holders’ name(s) appear(s) on the Original Notes.

If this Letter or any certificates of Original Notes or separate written instruments of transfer or exchange are signed or endorsed by trustees, executors, administrators, guardians, attorneys-in-fact, officers of corporations or other persons acting in a fiduciary or representative capacity, such persons should so indicate when signing and, unless waived by the Company, evidence satisfactory to the Company of their authority to so act must be submitted with this Letter.

Signature on a Letter or a notice of withdrawal, as the case may be, must be guaranteed by an Eligible Institution unless the Original Notes are being or were tendered (i) by a registered holder who has not completed the box entitled “Special Payment Instructions” or “Special Delivery Instructions” on the Letter or (ii) for the account of an Eligible Institution. In the event that signatures on a Letter or a notice of withdrawal, as the case may be, are required to be

guaranteed, such guarantee must be by a financial institution (including most banks, savings and loan associations and brokerage houses) that is a participant in the Securities Transfer Agents Medallion Program, the New York Stock Exchange Medallion Signature Program or the Stock Exchanges Medallion Program (each such entity an “Eligible Institution”).

4. Special Issuance and Delivery Instructions.

Tendering holders of Original Notes should indicate in the applicable box the name and address to which Exchange Notes issued pursuant to the Exchange Offers are to be issued or sent, if different from the name or address of the person signing this Letter. In the case of issuance in a different name, the employer identification or social security number of the person named must also be indicated. Holders tendering Original Notes by book-entry transfer may request that Original Notes not exchanged be credited to such account maintained at the Book-Entry Transfer Facility as such holder may designate hereon. If no such instructions are given, such Original Notes not exchanged will be returned to the name or address of the person signing this Letter.

5. Tax Identification Number and Backup Withholding.

An exchange of Original Notes for Exchange Notes pursuant to the Exchange Offers will not be treated as a taxable exchange or other taxable event for U.S. federal income tax purposes. In particular, no backup withholding or information reporting is required in connection with such an exchange. However, U.S. federal income tax law generally requires that payments of principal and interest on a note to a holder be subject to backup withholding unless such holder provides the payor with such holder’s correct Taxpayer Identification Number (“TIN”) or otherwise establishes a basis for an exemption. If the holder is an individual citizen or resident of the United States, the TIN is generally his or her social security number. If the payor is not provided with the current TIN or an adequate basis for an exemption, the holder may be subject to a $50 penalty imposed by the Internal Revenue Service (“IRS”). In addition, the holder may be subject to backup withholding in an amount that is currently 24% of all reportable payments of principal and interest.

Certain holders (including, among others, all corporations and certain foreign individuals) are not subject to these backup withholding and information reporting requirements. These holders should nevertheless complete IRS Form W-9 if such holder is a U.S. person to avoid possible erroneous backup withholding. However, if the holder is a nonresident alien individual or foreign entity not subject to backup withholding, to prevent backup withholding, the holder generally must provide a completed IRS Form W-8BEN (Certificate of Foreign Status of Beneficial Owner for United States Tax Withholding and Reporting (Individuals)) or other applicable IRS Form W-8. IRS Forms W-8 and W-9, and the instructions to such forms, may be obtained from the Exchange Agent or on the IRS’s website, www.irs.gov.

To prevent backup withholding on reportable payments of principal and interest, each holder that is a U.S. person must provide its correct TIN by completing IRS Form W-9, certifying that the TIN provided is correct (or that the holder is awaiting a TIN) and that (i) the holder is exempt from backup withholding, (ii) the holder has not been notified by the IRS that the holder is subject to a backup withholding as a result of a failure to report all interest or dividends or (iii) the IRS has notified the holder that the holder is no longer subject to backup withholding. If the Original Notes are in more than one name or are not in the name of the actual owner, the holder should consult the instructions to IRS Form W-9 for information on which TIN to report. If the holder does not have a TIN and has applied for one or intends to apply for one in the near future, the holder should consult the instructions to IRS Form W-9 for instructions on applying for a TIN and write “Applied for” in in the space provided for the TIN in Part I of IRS Form W-9. If “Applied for” is written in Part I of IRS Form W-9, backup withholding will nevertheless apply to all reportable payments made to the holder if such a holder does not furnish its TIN to the Exchange Agent by the time of payment.

If backup withholding applies, the payor will withhold the appropriate percentage (currently 24%) from payments to the holder. Backup withholding is not an additional tax. Rather, the U.S. federal income tax liability of persons subject to backup withholding will be reduced by the amount of tax withheld. If withholding results in an overpayment of taxes, a refund may be obtained from the IRS.

6. Transfer Taxes.

Holders who tender their Original Notes for Exchange Notes will not be obligated to pay any transfer taxes in connection therewith. If, however, Exchange Notes are to be delivered to, or are to be issued in the name of, any person other than the registered holder of the Original Notes tendered hereby, or if tendered Original Notes are

registered in the name of any person other than the person signing this Letter, or if a transfer tax is imposed for any reason other than the exchange of Original Notes in connection with the Exchange Offers, the amount of any transfer taxes (whether imposed on the registered holder or any other person) will be payable by the holder. If satisfactory evidence of payment of any such transfer taxes or exemption therefrom is not submitted herewith, the amount of such transfer taxes will be billed directly to the holder.

Except as provided in this Instruction 6, it will not be necessary for transfer tax stamps to be affixed to the Original Notes.

7. Waiver of Conditions.

The Company reserves the right, in its sole discretion, to waive satisfaction of any or all conditions enumerated in the Prospectus at any time and from time to time prior to the Expiration Date.

8. No Conditional Tenders.

No alternative, conditional, irregular or contingent tenders will be accepted. All tendering holders of Original Notes, by execution of this Letter or, in lieu thereof, an Agent’s Message, shall waive any right to receive notice of the acceptance of their Original Notes for exchange.

None of the Company, the Exchange Agent or any other person is obligated to give notice of any defect or irregularity with respect to any tender of Original Notes nor shall any of them incur any liability for failure to give any such notice.

9. Mutilated, Lost, Stolen or Destroyed Original Notes.

Any holder whose Original Notes have been mutilated, lost, stolen or destroyed should contact the Exchange Agent at the address indicated above for further instructions.

10. Requests for Assistance or Additional Copies.

Questions relating to the procedure for tendering, as well as requests for additional copies of the Prospectus and this Letter, may be directed to the Exchange Agent, at the address and telephone number indicated above

Annex I

Series of Original Notes	Status	CUSIP
2.875% Senior Notes due 2020	144A	110122 BC1
2.875% Senior Notes due 2020	Reg S	U11009 AC8
3.950% Senior Notes due 2020	144A	110122 BD9
3.950% Senior Notes due 2020	Reg S	U11009 AD6
Senior Floating Rate Notes due 2020	144A	110122 CE6
Senior Floating Rate Notes due 2020	Reg S	U11009 BE3
2.875% Senior Notes due 2021	144A	110122 BE7
2.875% Senior Notes due 2021	Reg S	U11009 AE4
2.250% Senior Notes due 2021	144A	110122 BF4
2.250% Senior Notes due 2021	Reg S	U11009 AF1
2.550% Senior Notes due 2021	144A	110122 BX5
2.550% Senior Notes due 2021	Reg S	U11009 AX2
3.250% Senior Notes due 2022	144A	110122 BG2
3.250% Senior Notes due 2022	Reg S	U11009 AG9
3.550% Senior Notes due 2022	144A	110122 BH0
3.550% Senior Notes due 2022	Reg S	U11009 AH7
Senior Floating Rate Notes due 2022	144A	110122 CF3
Senior Floating Rate Notes due 2022	Reg S	U11009 BF0
2.600% Senior Notes due 2022	144A	110122 BY3
2.600% Senior Notes due 2022	Reg S	U11009 AY0
2.750% Senior Notes due 2023	144A	110122 BJ6
2.750% Senior Notes due 2023	Reg S	U11009 AJ3
3.250% Senior Notes due 2023	144A	110122 BK3
3.250% Senior Notes due 2023	Reg S	U11009 AK0
4.000% Senior Notes due 2023	144A	110122 BL1
4.000% Senior Notes due 2023	Reg S	U11009 AL8
3.625% Senior Notes due 2024	144A	110122 BM9
3.625% Senior Notes due 2024	Reg S	U11009 AM6
2.900% Senior Notes due 2024	144A	110122 BZ0
2.900% Senior Notes due 2024	Reg S	U11009 AZ7
3.875% Senior Notes due 2025	144A	110122 BN7
3.875% Senior Notes due 2025	Reg S	U11009 AN4
3.200% Senior Notes due 2026	144A	110122 CA4
3.200% Senior Notes due 2026	Reg S	U11009 BA1
3.450% Senior Notes due 2027	144A	110122 BP2
3.450% Senior Notes due 2027	Reg S	U11009 AP9
3.900% Senior Notes due 2028	144A	110122 BQ0
3.900% Senior Notes due 2028	Reg S	U11009 AQ7
3.400% Senior Notes due 2029	144A	110122 CB2
3.400% Senior Notes due 2029	Reg S	U11009 BB9
4.125% Senior Notes due 2039	144A	110122 CC0
4.125% Senior Notes due 2039	Reg S	U11009 BC7
5.700% Senior Notes due 2040	144A	110122 BR8
5.700% Senior Notes due 2040	Reg S	U11009 AR5
5.250% Senior Notes due 2043	144A	110122 BS6
5.250% Senior Notes due 2043	Reg S	U11009 AS3
4.625% Senior Notes due 2044	144A	110122 BT4
4.625% Senior Notes due 2044	Reg S	U11009 AT1
5.000% Senior Notes due 2045	144A	110122 BU1

Series of Original Notes	Status	CUSIP
5.000% Senior Notes due 2045	Reg S	U11009 AU8
4.350% Senior Notes due 2047	144A	110122 BV9
4.350% Senior Notes due 2047	Reg S	U11009 AV6
4.550% Senior Notes due 2048	144A	110122 BW7
4.550% Senior Notes due 2048	Reg S	U11009 AW4
4.250% Senior Notes due 2049	144A	110122 CD8
4.250% Senior Notes due 2049	Reg S	U11009 BD5

Bristol-Myers Squibb (BMY) S-4Registration of securities issued in business combination transactions