Exhibit 99.2
BRISTOL-MYERS SQUIBB COMPANY
NET SALES
QUARTERLY SALES TREND ANALYSIS
($ in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | 2006 | | | 2007 | | % Change | |
| | 1st Qtr | | | 2nd Qtr | | | 6 Months | | | 3rd Qtr | | | 9 Months | | | 4th Qtr | | | Year | | | 1st Qtr | | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
Net Sales | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Pharmaceuticals | | $ | 3,700 | | | $ | 3,859 | | | $ | 7,559 | | | $ | 3,154 | | | $ | 10,713 | | | $ | 3,148 | | | $ | 13,861 | | | $ | 3,457 | | | | | | | | | | | | | | | -7 | % | | -7 | % |
| | | | | | | | | | | | | | | | |
US Pharmaceuticals | | | 2,064 | | | | 2,197 | | | | 4,261 | | | | 1,609 | | | | 5,870 | | | | 1,501 | | | | 7,371 | | | | 1,932 | | | | | | | | | | | | | | | -6 | % | | -6 | % |
Primary Care | | | 1,409 | | | | 1,441 | | | | 2,850 | | | | 819 | | | | 3,669 | | | | 648 | | | | 4,317 | | | | 1,090 | | | | | | | | | | | | | | | -23 | % | | -23 | % |
Oncology/Virology | | | 419 | | | | 458 | | | | 877 | | | | 494 | | | | 1,371 | | | | 525 | | | | 1,896 | | | | 504 | | | | | | | | | | | | | | | 20 | % | | 20 | % |
Neuroscience | | | 231 | | | | 280 | | | | 511 | | | | 262 | | | | 773 | | | | 297 | | | | 1,070 | | | | 298 | | | | | | | | | | | | | | | 29 | % | | 29 | % |
Immunoscience | | | 5 | | | | 18 | | | | 23 | | | | 34 | | | | 57 | | | | 31 | | | | 88 | | | | 40 | | | | | | | | | | | | | | | * | | | * | |
| | | | | | | | | | | | | | | | |
Europe and Middle East Medicines | | | 1,024 | | | | 1,000 | | | | 2,024 | | | | 886 | | | | 2,910 | | | | 934 | | | | 3,844 | | | | 916 | | | | | | | | | | | | | | | -11 | % | | -11 | % |
| | | | | | | | | | | | | | | | |
Latin America/Canada | | | 288 | | | | 303 | | | | 591 | | | | 300 | | | | 891 | | | | 306 | | | | 1,197 | | | | 297 | | | | | | | | | | | | | | | 3 | % | | 3 | % |
| | | | | | | | | | | | | | | | |
Asia/Pacific Medicines | | | 279 | | | | 320 | | | | 599 | | | | 318 | | | | 917 | | | | 349 | | | | 1,266 | | | | 289 | | | | | | | | | | | | | | | 4 | % | | 4 | % |
| | | | | | | | | | | | | | | | |
Nutritionals | | | 565 | | | | 582 | | | | 1,147 | | | | 582 | | | | 1,729 | | | | 618 | | | | 2,347 | | | | 606 | | | | | | | | | | | | | | | 7 | % | | 7 | % |
| | | | | | | | | | | | | | | | |
Other Health Care | | | 411 | | | | 430 | | | | 841 | | | | 418 | | | | 1,259 | | | | 447 | | | | 1,706 | | | | 413 | | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
ConvaTec | | | 230 | | | | 262 | | | | 492 | | | | 265 | | | | 757 | | | | 291 | | | | 1,048 | | | | 254 | | | | | | | | | | | | | | | 10 | % | | 10 | % |
| | | | | | | | | | | | | | | | |
Medical Imaging | | | 181 | | | | 168 | | | | 349 | | | | 153 | | | | 502 | | | | 156 | | | | 658 | | | | 159 | | | | | | | | | | | | | | | -12 | % | | -12 | % |
| | | | | | | | | | | | | | | | |
Total Company | | $ | 4,676 | | | $ | 4,871 | | | $ | 9,547 | | | $ | 4,154 | | | $ | 13,701 | | | $ | 4,213 | | | $ | 17,914 | | | $ | 4,476 | | | | | | | | | | | | | | | -4 | % | | -4 | % |
| | | |
| | 2006 | | | 2007 | | Basis Point Change | |
| | 1st Qtr | | | 2nd Qtr | | | 6 Months | | | 3rd Qtr | | | 9 Months | | | 4th Qtr | | | Year | | | 1st Qtr | | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
% of Total Sales | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Pharmaceuticals | | | 79.1 | % | | | 79.2 | % | | | 79.2 | % | | | 75.9 | % | | | 78.2 | % | | | 74.7 | % | | | 77.4 | % | | | 77.2 | % | | | | | | | | | | | | | | (190 | ) | | (190 | ) |
| | | | | | | | | | | | | | | | |
US Pharmaceuticals | | | 44.1 | % | | | 45.1 | % | | | 44.6 | % | | | 38.7 | % | | | 42.8 | % | | | 35.6 | % | | | 41.1 | % | | | 43.2 | % | | | | | | | | | | | | | | (90 | ) | | (90 | ) |
Primary Care | | | 30.1 | % | | | 29.6 | % | | | 29.9 | % | | | 19.7 | % | | | 26.8 | % | | | 15.4 | % | | | 24.1 | % | | | 24.4 | % | | | | | | | | | | | | | | (570 | ) | | (570 | ) |
Oncology/Virology | | | 9.0 | % | | | 9.4 | % | | | 9.2 | % | | | 11.9 | % | | | 10.0 | % | | | 12.5 | % | | | 10.5 | % | | | 11.3 | % | | | | | | | | | | | | | | 230 | | | 230 | |
Neuroscience | | | 4.9 | % | | | 5.7 | % | | | 5.3 | % | | | 6.3 | % | | | 5.6 | % | | | 7.0 | % | | | 6.0 | % | | | 6.7 | % | | | | | | | | | | | | | | 180 | | | 180 | |
Immunoscience | | | 0.1 | % | | | 0.4 | % | | | 0.2 | % | | | 0.8 | % | | | 0.4 | % | | | 0.7 | % | | | 0.5 | % | | | 0.8 | % | | | | | | | | | | | | | | 70 | | | 70 | |
| | | | | | | | | | | | | | | | |
Europe and Middle East Medicines | | | 21.9 | % | | | 20.5 | % | | | 21.2 | % | | | 21.3 | % | | | 21.2 | % | | | 22.2 | % | | | 21.5 | % | | | 20.5 | % | | | | | | | | | | | | | | (140 | ) | | (140 | ) |
| | | | | | | | | | | | | | | | |
Latin America/Canada | | | 6.2 | % | | | 6.2 | % | | | 6.2 | % | | | 7.2 | % | | | 6.5 | % | | | 7.3 | % | | | 6.7 | % | | | 6.6 | % | | | | | | | | | | | | | | 40 | | | 40 | |
| | | | | | | | | | | | | | | | |
Asia/Pacific Medicines | | | 6.0 | % | | | 6.6 | % | | | 6.3 | % | | | 7.7 | % | | | 6.7 | % | | | 8.3 | % | | | 7.1 | % | | | 6.5 | % | | | | | | | | | | | | | | 50 | | | 50 | |
| | | | | | | | | | | | | | | | |
Nutritionals | | | 12.1 | % | | | 12.0 | % | | | 12.0 | % | | | 14.0 | % | | | 12.6 | % | | | 14.7 | % | | | 13.1 | % | | | 13.5 | % | | | | | | | | | | | | | | 140 | | | 140 | |
| | | | | | | | | | | | | | | | |
Other Health Care | | | 8.8 | % | | | 8.8 | % | | | 8.8 | % | | | 10.1 | % | | | 9.2 | % | | | 10.6 | % | | | 9.5 | % | | | 9.3 | % | | | | | | | | | | | | | | 50 | | | 50 | |
| | | | | | | | | | | | | | | | |
ConvaTec | | | 4.9 | % | | | 5.4 | % | | | 5.2 | % | | | 6.4 | % | | | 5.5 | % | | | 6.9 | % | | | 5.8 | % | | | 5.7 | % | | | | | | | | | | | | | | 80 | | | 80 | |
| | | | | | | | | | | | | | | | |
Medical Imaging | | | 3.9 | % | | | 3.4 | % | | | 3.6 | % | | | 3.7 | % | | | 3.7 | % | | | 3.7 | % | | | 3.7 | % | | | 3.6 | % | | | | | | | | | | | | | | (30 | ) | | (30 | ) |
| | | | | | | | | | | | | | | | |
Total Company | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | 100.0 | % | | | | | | | | | | | | | | | | | | |
BRISTOL-MYERS SQUIBB COMPANY
SEGMENT SALES AND COMPOSITION OF CHANGE IN SALES FOR TOTAL COMPANY
FOR THE PERIOD ENDED MARCH 31, 2007
($ in millions)
YEAR-TO-DATE
| | | | | | | | | | | | | | | | | | | | |
| | Pharmaceuticals Group | | | Nutritionals | | | Convatec | | | Medical Imaging | | | Total Company | |
Price Increases/(Decreases) | | | — | | | | 2 | % | | | -1 | % | | | -3 | % | | | — | |
Foreign Exchange | | | 2 | % | | | 2 | % | | | 5 | % | | | — | | | | 2 | % |
Volume | | | -9 | % | | | 3 | % | | | 6 | % | | | -9 | % | | | -6 | % |
| | | | | | | | | | | | | | | | | | | | |
Total Change | | | -7 | % | | | 7 | % | | | 10 | % | | | -12 | % | | | -4 | % |
| | | | | | | | | | | | | | | | | | | | |
Total 2007 Period to Date Sales | | $ | 3,457 | | | $ | 606 | | | $ | 254 | | | $ | 159 | | | $ | 4,476 | |
Total 2006 Period to Date Sales | | $ | 3,700 | | | $ | 565 | | | $ | 230 | | | $ | 181 | | | $ | 4,676 | |
BRISTOL-MYERS SQUIBB COMPANY
CONSOLIDATED STATEMENT OF EARNINGS
($ in millions, except per share amounts)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | 2006 | | | 2007 | | % Change | |
| | 1st Qtr | | | 2nd Qtr | | | 6 Months | | | 3rd Qtr | | | 9 Months | | | 4th Qtr | | | Year | | | 1st Qtr | | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
Net Sales | | $ | 4,676 | | | $ | 4,871 | | | $ | 9,547 | | | $ | 4,154 | | | $ | 13,701 | | | $ | 4,213 | | | $ | 17,914 | | | $ | 4,476 | | | | | | | | | | | | | | | -4 | % | | -4 | % |
| | | | | | | | | | | | | | | | |
Cost of products sold | | | 1,476 | | | | 1,568 | | | | 3,044 | | | | 1,465 | | | | 4,509 | | | | 1,447 | | | | 5,956 | | | | 1,392 | | | | | | | | | | | | | | | -6 | % | | -6 | % |
Marketing, selling and administrative | | | 1,238 | | | | 1,181 | | | | 2,419 | | | | 1,189 | | | | 3,608 | | | | 1,311 | | | | 4,919 | | | | 1,158 | | | | | | | | | | | | | | | -6 | % | | -6 | % |
Advertising and product promotion | | | 295 | | | | 352 | | | | 647 | | | | 286 | | | | 933 | | | | 418 | | | | 1,351 | | | | 269 | | | | | | | | | | | | | | | -9 | % | | -9 | % |
Research and development | | | 750 | | | | 740 | | | | 1,490 | | | | 756 | | | | 2,246 | | | | 821 | | | | 3,067 | | | | 807 | | | | | | | | | | | | | | | 8 | % | | 8 | % |
Provision for restructuring, net | | | 1 | | | | 3 | | | | 4 | | | | 2 | | | | 6 | | | | 53 | | | | 59 | | | | 37 | | | | | | | | | | | | | | | * | | | * | |
Litigation (income)/charges, net | | | (21) | | | | (14) | | | | (35) | | | | (9) | | | | (44) | | | | 346 | | | | 302 | | | | — | | | | | | | | | | | | | | | 100 | % | | 100 | % |
Gain on sale of business and product asset | | | (200) | | | | — | | | | (200) | | | | — | | | | (200) | | | | — | | | | (200) | | | | — | | | | | | | | | | | | | | | 100 | % | | 100 | % |
Equity in net income of affiliates | | | (93) | | | | (125) | | | | (218) | | | | (118) | | | | (336) | | | | (138) | | | | (474) | | | | (126) | | | | | | | | | | | | | | | -35 | % | | -35 | % |
Other expense/(income), net | | | 37 | | | | 56 | | | | 93 | | | | (34) | | | | 59 | | | | 240 | | | | 299 | | | | 22 | | | | | | | | | | | | | | | -41 | % | | -41 | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Total expenses | | | 3,483 | | | | 3,761 | | | | 7,244 | | | | 3,537 | | | | 10,781 | | | | 4,498 | | | | 15,279 | | | | 3,559 | | | | | | | | | | | | | | | 2 | % | | 2 | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Earnings/(Loss) Before Minority Interest and Income Taxes | | | 1,193 | | | | 1,110 | | | | 2,303 | | | | 617 | | | | 2,920 | | | | (285) | | | | 2,635 | | | | 917 | | | | | | | | | | | | | | | -23 | % | | -23 | % |
| | | | | | | | | | | | | | | | |
Provision/(Benefit) for income taxes | | | 328 | | | | 256 | | | | 584 | | | | 193 | | | | 777 | | | | (167) | | | | 610 | | | | 86 | | | | | | | | | | | | | | | -74 | % | | -74 | % |
Minority interest, net of taxes | | | 151 | | | | 187 | | | | 338 | | | | 86 | | | | 424 | | | | 16 | | | | 440 | | | | 141 | | | | | | | | | | | | | | | -7 | % | | -7 | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Net Earnings/(Loss) | | $ | 714 | | | $ | 667 | | | $ | 1,381 | | | $ | 338 | | | $ | 1,719 | | | $ | (134) | | | $ | 1,585 | | | | 690 | | | | | | | | | | | | | | | -3 | % | | -3 | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Interest expense on conversion of convertible debt bonds, net of tax | | | 8 | | | | 8 | | | | 16 | | | | 9 | | | | 25 | | | | — | (1) | | | — | (2) | | | 9 | | | | | | | | | | | | | | | | | | | |
Net Earnings/(Loss) used for diluted earnings per common share calculation | | $ | 722 | | | $ | 675 | | | $ | 1,397 | | | $ | 347 | | | $ | 1,744 | | | $ | (134) | (1) | | $ | 1,585 | (2) | | | 699 | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Diluted Earnings/(Loss) per Common Share** | | $ | 0.36 | | | $ | 0.34 | | | $ | 0.70 | | | $ | 0.17 | | | $ | 0.88 | | | $ | (0.07) | (1) | | $ | 0.81 | (2) | | $ | 0.35 | | | | | | | | | | | | | | | -3 | % | | -3 | % |
| | | | | | | | | | | | | | | | |
Average Common Shares Outstanding - Diluted | | | 1,988 | | | | 1,994 | | | | 1,992 | | | | 1,992 | | | | 1,991 | | | | 1,961 | (1) | | | 1,963 | (2) | | | 1,997 | | | | | | | | | | | | | | | — | | | — | |
Dividends declared per common share | | $ | 0.28 | | | $ | 0.28 | | | $ | 0.56 | | | $ | 0.28 | | | $ | 0.84 | | | $ | 0.28 | | | $ | 1.12 | | | $ | 0.28 | | | | | | | | | | | | | | | — | | | — | |
| | | |
| | 2006 | | | 2007 | | Basis Point Change | |
| | 1st Qtr | | | 2nd Qtr | | | 6 Months | | | 3rd Qtr | | | 9 Months | | | 4th Qtr | | | Year | | | 1st Qtr | | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
% of Net Sales | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Gross Margin | | | 68.4 | % | | | 67.8 | % | | | 68.1 | % | | | 64.7 | % | | | 67.1 | % | | | 65.7 | % | | | 66.8 | % | | | 68.9 | % | | | | | | | | | | | | | | 50 | | | 50 | |
| | | | | | | | | | | | | | | | |
Cost of products sold | | | 31.6 | % | | | 32.2 | % | | | 31.9 | % | | | 35.3 | % | | | 32.9 | % | | | 34.3 | % | | | 33.2 | % | | | 31.1 | % | | | | | | | | | | | | | | (50) | | | (50) | |
Marketing, selling and administrative | | | 26.5 | % | | | 24.2 | % | | | 25.3 | % | | | 28.6 | % | | | 26.3 | % | | | 31.1 | % | | | 27.5 | % | | | 25.9 | % | | | | | | | | | | | | | | (60) | | | (60) | |
Advertising and product promotion | | | 6.3 | % | | | 7.2 | % | | | 6.8 | % | | | 6.9 | % | | | 6.8 | % | | | 9.9 | % | | | 7.5 | % | | | 6.0 | % | | | | | | | | | | | | | | (30) | | | (30) | |
Research and development | | | 16.0 | % | | | 15.2 | % | | | 15.6 | % | | | 18.2 | % | | | 16.4 | % | | | 19.5 | % | | | 17.1 | % | | | 18.0 | % | | | | | | | | | | | | | | 200 | | | 200 | |
Total expenses | | | 74.5 | % | | | 77.2 | % | | | 75.9 | % | | | 85.1 | % | | | 78.7 | % | | | 106.8 | % | | | 85.3 | % | | | 79.5 | % | | | | | | | | | | | | | | 500 | | | 500 | |
| | | | | | | | | | | | | | | | |
Earnings/(Loss) Before Minority Interest and Income Taxes | | | 25.5 | % | | | 22.8 | % | | | 24.1 | % | | | 14.9 | % | | | 21.3 | % | | | -6.8 | % | | | 14.7 | % | | | 20.5 | % | | | | | | | | | | | | | | (500) | | | (500) | |
| | | | | | | | | | | | | | | | |
Net Earnings/(Loss) | | | 15.3 | % | | | 13.7 | % | | | 14.5 | % | | | 8.1 | % | | | 12.5 | % | | | -3.2 | % | | | 8.8 | % | | | 15.4 | % | | | | | | | | | | | | | | 10 | | | 10 | |
| | | | | | | | | | | | | | | | |
Other Ratios | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Effective Tax Rate | | | 27.5 | % | | | 23.1 | % | | | 25.4 | % | | | 31.3 | % | | | 26.6 | % | | | 58.6 | % | | | 23.1 | % | | | 9.4 | % | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | |
| | 2006 | | | 2007 | | % Change | |
| | 1st Qtr | | | 2nd Qtr | | | 6 Months | | | 3rd Qtr | | | 9 Months | | | 4th Qtr | | | Year | | | 1st Qtr | | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
Other (Income)/Expense, net | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | |
Interest expense | | $ | 116 | | | $ | 124 | | | $ | 240 | | | $ | 130 | | | $ | 370 | | | $ | 128 | | | $ | 498 | | | $ | 109 | | | | | | | | | | | | | | | -6 | % | | -6 | % |
Interest income | | | (62) | | | | (65) | | | | (127) | | | | (74) | | | | (201) | | | | (73) | | | | (274) | | | | (53) | | | | | | | | | | | | | | | 15 | % | | 15 | % |
Foreign exchange transaction (gains)/losses | | | (12) | | | | 23 | | | | 11 | | | | (11) | | | | — | | | | 6 | | | | 6 | | | | 8 | | | | | | | | | | | | | | | 167 | % | | 167 | % |
Other, net | | | (5) | | | | (26) | | | | (31) | | | | (79) | | | | (110) | | | | 179 | | | | 69 | | | | (42) | | | | | | | | | | | | | | | * | | | * | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | $ | 37 | | | $ | 56 | | | $ | 93 | | | $ | (34) | | | $ | 59 | | | $ | 240 | | | $ | 299 | | | $ | 22 | | | | | | | | | | | | | | | -41 | % | | -41 | % |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
** | amounts may not calculate due to rounding differences between continuing and discontinued operations. |
(1) | as a result of the Q4 2006 net loss, Diluted Average Common Shares Outstanding and Loss per Common Share are equal to Basic Average Common Shares Outstanding and Loss per Common Share. |
(2) | assumed interest amount and the assumed conversion of convertible debt are not used for Diluted Earnings per Common Share calculation as the impact of convertible debt is anti-dilutive. |
BRISTOL-MYERS SQUIBB COMPANY
WORLDWIDE NET SALES BY PRODUCT
QUARTERLY SALES TREND ANALYSIS
($ in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | 2006 | | 2007 | | % Change | |
| | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
Total Company | | $ | 4,676 | | $ | 4,871 | | $ | 9,547 | | $ | 4,154 | | $ | 13,701 | | $ | 4,213 | | $ | 17,914 | | $ | 4,476 | | | | | | | | | | | | | | -4 | % | | -4 | % |
| | | | | | | | | | | | | | | | |
PHARMACEUTICALS | | | 3,700 | | | 3,859 | | | 7,559 | | | 3,154 | | | 10,713 | | | 3,148 | | | 13,861 | | | 3,457 | | | | | | | | | | | | | | -7 | % | | -7 | % |
| | | | | | | | | | | | | | | | |
Cardiovascular | | | 1,917 | | | 1,907 | | | 3,824 | | | 1,239 | | | 5,063 | | | 1,093 | | | 6,156 | | | 1,475 | | | | | | | | | | | | | | -23 | % | | -23 | % |
Plavix | | | 986 | | | 1,145 | | | 2,131 | | | 630 | | | 2,761 | | | 496 | | | 3,257 | | | 938 | | | | | | | | | | | | | | -5 | % | | -5 | % |
Pravachol | | | 536 | | | 323 | | | 859 | | | 192 | | | 1,051 | | | 146 | | | 1,197 | | | 135 | | | | | | | | | | | | | | -75 | % | | -75 | % |
Avapro/ Avalide | | | 233 | | | 280 | | | 513 | | | 277 | | | 790 | | | 307 | | | 1,097 | | | 270 | | | | | | | | | | | | | | 16 | % | | 16 | % |
Coumadin | | | 55 | | | 55 | | | 110 | | | 53 | | | 163 | | | 57 | | | 220 | | | 46 | | | | | | | | | | | | | | -16 | % | | -16 | % |
| | | | | | | | | | | | | | | | |
Virology | | | 468 | | | 524 | | | 992 | | | 532 | | | 1,524 | | | 580 | | | 2,104 | | | 590 | | | | | | | | | | | | | | 26 | % | | 26 | % |
Reyataz | | | 207 | | | 236 | | | 443 | | | 233 | | | 676 | | | 255 | | | 931 | | | 263 | | | | | | | | | | | | | | 27 | % | | 27 | % |
Sustiva Franchise*** | | | 175 | | | 193 | | | 368 | | | 201 | | | 569 | | | 222 | | | 791 | | | 226 | | | | | | | | | | | | | | 29 | % | | 29 | % |
Baraclude | | | 11 | | | 14 | | | 25 | | | 22 | | | 47 | | | 36 | | | 83 | | | 45 | | | | | | | | | | | | | | * | | | * | |
| | | | | | | | | | | | | | | | |
Oncology | | | 361 | | | 401 | | | 762 | | | 399 | | | 1,161 | | | 394 | | | 1,555 | | | 355 | | | | | | | | | | | | | | -2 | % | | -2 | % |
Erbitux | | | 138 | | | 172 | | | 310 | | | 175 | | | 485 | | | 167 | | | 652 | | | 160 | | | | | | | | | | | | | | 16 | % | | 16 | % |
Taxol | | | 147 | | | 149 | | | 296 | | | 137 | | | 433 | | | 130 | | | 563 | | | 111 | | | | | | | | | | | | | | -24 | % | | -24 | % |
Sprycel | | | — | | | — | | | — | | | 11 | | | 11 | | | 14 | | | 25 | | | 21 | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
Affective (Psychiatric) Disorders | | | 323 | | | 376 | | | 699 | | | 354 | | | 1,053 | | | 404 | | | 1,457 | | | 408 | | | | | | | | | | | | | | 26 | % | | 26 | % |
Abilify** | | | 283 | | | 324 | | | 607 | | | 313 | | | 920 | | | 362 | | | 1,282 | | | 366 | | | | | | | | | | | | | | 29 | % | | 29 | % |
| | | | | | | | | | | | | | | | |
Immunoscience | | | 5 | | | 18 | | | 23 | | | 34 | | | 57 | | | 32 | | | 89 | | | 41 | | | | | | | | | | | | | | * | | | * | |
Orencia | | | 5 | | | 18 | | | 23 | | | 34 | | | 57 | | | 32 | | | 89 | | | 41 | | | | | | | | | | | | | | * | | | * | |
| | | | | | | | | | | | | | | | |
Other Pharmaceuticals | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Efferalgan | | | 68 | | | 62 | | | 130 | | | 62 | | | 192 | | | 74 | | | 266 | | | 81 | | | | | | | | | | | | | | 19 | % | | 19 | % |
| | | | | | | | | | | | | | | | |
NUTRITIONALS | | | 565 | | | 582 | | | 1,147 | | | 582 | | | 1,729 | | | 618 | | | 2,347 | | | 606 | | | | | | | | | | | | | | 7 | % | | 7 | % |
Enfamil | | | 237 | | | 253 | | | 490 | | | 246 | | | 736 | | | 271 | | | 1,007 | | | 254 | | | | | | | | | | | | | | 7 | % | | 7 | % |
Enfagrow | | | 67 | | | 59 | | | 126 | | | 69 | | | 195 | | | 67 | | | 262 | | | 72 | | | | | | | | | | | | | | 7 | % | | 7 | % |
| | | | | | | | | | | | | | | | |
OTHER HEALTH CARE | | | 411 | | | 430 | | | 841 | | | 418 | | | 1,259 | | | 447 | | | 1,706 | | | 413 | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
CONVATEC | | | 230 | | | 262 | | | 492 | | | 265 | | | 757 | | | 291 | | | 1,048 | | | 254 | | | | | | | | | | | | | | 10 | % | | 10 | % |
Ostomy | | | 123 | | | 141 | | | 264 | | | 139 | | | 403 | | | 151 | | | 554 | | | 130 | | | | | | | | | | | | | | 6 | % | | 6 | % |
Wound Therapeutics | | | 98 | | | 107 | | | 205 | | | 113 | | | 318 | | | 123 | | | 441 | | | 107 | | | | | | | | | | | | | | 9 | % | | 9 | % |
| | | | | | | | | | | | | | | | |
MEDICAL IMAGING | | | 181 | | | 168 | | | 349 | | | 153 | | | 502 | | | 156 | | | 658 | | | 159 | | | | | | | | | | | | | | -12 | % | | -12 | % |
Cardiolite | | | 103 | | | 105 | | | 208 | | | 97 | | | 305 | | | 103 | | | 408 | | | 99 | | | | | | | | | | | | | | -4 | % | | -4 | % |
** | Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd. |
*** | Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. |
BRISTOL-MYERS SQUIBB COMPANY
DOMESTIC* NET SALES BY PRODUCT
QUARTERLY SALES TREND ANALYSIS
($ in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | 2006 | | 2007 | | % Change | | | % Change in U.S. Total Prescription**** | |
| | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | | | Qtr vs. Qtr | | | YTD vs. YTD | |
Total Company | | $ | 2,638 | | $ | 2,806 | | $ | 5,444 | | $ | 2,170 | | $ | 7,614 | | $ | 2,115 | | $ | 9,729 | | $ | 2,505 | | | | | | | | | | | | | | -5 | % | | -5 | % | | | | | | |
| | | | | | | | | | | | | | | | | | |
PHARMACEUTICALS | | | 2,076 | | | 2,205 | | | 4,281 | | | 1,619 | | | 5,900 | | | 1,517 | | | 7,417 | | | 1,944 | | | | | | | | | | | | | | -6 | % | | -6 | % | | | | | | |
| | | | | | | | | | | | | | | | | | |
Cardiovascular | | | 1,341 | | | 1,330 | | | 2,671 | | | 752 | | | 3,423 | | | 616 | | | 4,039 | | | 1,045 | | | | | | | | | | | | | | -22 | % | | -22 | % | | | | | | |
Plavix | | | 850 | | | 988 | | | 1,838 | | | 474 | | | 2,312 | | | 343 | | | 2,655 | | | 787 | | | | | | | | | | | | | | -7 | % | | -7 | % | | -28 | % | | -28 | % |
Pravachol | | | 302 | | | 128 | | | 430 | | | 73 | | | 503 | | | 50 | | | 553 | | | 57 | | | | | | | | | | | | | | -81 | % | | -81 | % | | -86 | % | | -86 | % |
Avapro/ Avalide | | | 139 | | | 167 | | | 306 | | | 159 | | | 465 | | | 182 | | | 647 | | | 163 | | | | | | | | | | | | | | 17 | % | | 17 | % | | -1 | % | | -1 | % |
Coumadin | | | 47 | | | 46 | | | 93 | | | 45 | | | 138 | | | 48 | | | 186 | | | 38 | | | | | | | | | | | | | | -19 | % | | -19 | % | | -17 | % | | -17 | % |
| | | | | | | | | | | | | | | | | | |
Virology | | | 259 | | | 270 | | | 529 | | | 292 | | | 821 | | | 327 | | | 1,148 | | | 319 | | | | | | | | | | | | | | 23 | % | | 23 | % | | | | | | |
Reyataz | | | 119 | | | 122 | | | 241 | | | 129 | | | 370 | | | 144 | | | 514 | | | 143 | | | | | | | | | | | | | | 20 | % | | 20 | % | | 17 | % | | 17 | % |
Sustiva Franchise***** | | | 108 | | | 115 | | | 223 | | | 128 | | | 351 | | | 144 | | | 495 | | | 144 | | | | | | | | | | | | | | 33 | % | | 33 | % | | 25 | % | | 25 | % |
Baraclude | | | 9 | | | 9 | | | 18 | | | 14 | | | 32 | | | 18 | | | 50 | | | 17 | | | | | | | | | | | | | | 89 | % | | 89 | % | | 127 | % | | 127 | % |
| | | | | | | | | | | | | | | | | | |
Oncology | | | 159 | | | 187 | | | 346 | | | 201 | | | 547 | | | 195 | | | 742 | | | 182 | | | | | | | | | | | | | | 14 | % | | 14 | % | | | | | | |
Erbitux | | | 136 | | | 172 | | | 308 | | | 173 | | | 481 | | | 165 | | | 646 | | | 158 | | | | | | | | | | | | | | 16 | % | | 16 | % | | N/A | | | N/A | |
Taxol | | | 4 | | | 4 | | | 8 | | | 2 | | | 10 | | | 2 | | | 12 | | | 4 | | | | | | | | | | | | | | — | | | — | | | N/A | | | N/A | |
Sprycel | | | — | | | — | | | — | | | 11 | | | 11 | | | 11 | | | 22 | | | 10 | | | | | | | | | | | | | | — | | | — | | | N/A | | | N/A | |
| | | | | | | | | | | | | | | | | | |
Affective (Psychiatric) Disorders | | | 237 | | | 286 | | | 523 | | | 266 | | | 789 | | | 302 | | | 1,091 | | | 305 | | | | | | | | | | | | | | 29 | % | | 29 | % | | | | | | |
Abilify** | | | 231 | | | 267 | | | 498 | | | 260 | | | 758 | | | 294 | | | 1,052 | | | 293 | | | | | | | | | | | | | | 27 | % | | 27 | % | | 14 | % | | 14 | % |
| | | | | | | | | | | | | | | | | | |
Immunoscience | | | 5 | | | 18 | | | 23 | | | 34 | | | 57 | | | 31 | | | 88 | | | 40 | | | | | | | | | | | | | | * | ** | | * | ** | | | | | | |
Orencia | | | 5 | | | 18 | | | 23 | | | 34 | | | 57 | | | 31 | | | 88 | | | 40 | | | | | | | | | | | | | | * | ** | | * | ** | | N/A | | | N/A | |
| | | | | | | | | | | | | | | | | | |
Other Pharmaceuticals | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Efferalgan | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | | | | | | | | | | | | — | | | — | | | N/A | | | N/A | |
| | | | | | | | | | | | | | | | | | |
NUTRITIONALS | | | 247 | | | 282 | | | 529 | | | 267 | | | 796 | | | 295 | | | 1,091 | | | 274 | | | | | | | | | | | | | | 11 | % | | 11 | % | | | | | | |
Enfamil | | | 155 | | | 174 | | | 329 | | | 169 | | | 498 | | | 190 | | | 688 | | | 171 | | | | | | | | | | | | | | 10 | % | | 10 | % | | N/A | | | N/A | |
Enfagrow | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | — | | | | | | | | | | | | | | — | | | — | | | N/A | | | N/A | |
| | | | | | | | | | | | | | | | | | |
OTHER HEALTH CARE | | | 231 | | | 226 | | | 457 | | | 215 | | | 672 | | | 232 | | | 904 | | | 214 | | | | | | | | | | | | | | -7 | % | | -7 | % | | | | | | |
| | | | | | | | | | | | | | | | | | |
CONVATEC | | | 73 | | | 85 | | | 158 | | | 84 | | | 242 | | | 101 | | | 343 | | | 78 | | | | | | | | | | | | | | 7 | % | | 7 | % | | | | | | |
Ostomy | | | 34 | | | 41 | | | 75 | | | 39 | | | 114 | | | 45 | | | 159 | | | 34 | | | | | | | | | | | | | | — | | | — | | | N/A | | | N/A | |
Wound Therapeutics | | | 30 | | | 34 | | | 64 | | | 36 | | | 100 | | | 43 | | | 143 | | | 32 | | | | | | | | | | | | | | 7 | % | | 7 | % | | N/A | | | N/A | |
| | | | | | | | | | | | | | | | | | |
MEDICAL IMAGING | | | 158 | | | 141 | | | 299 | | | 131 | | | 430 | | | 131 | | | 561 | | | 136 | | | | | | | | | | | | | | -14 | % | | -14 | % | | | | | | |
Cardiolite | | | 91 | | | 91 | | | 182 | | | 86 | | | 268 | | | 90 | | | 358 | | | 87 | | | | | | | | | | | | | | -4 | % | | -4 | % | | N/A | | | N/A | |
* | This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales. |
** | Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd. |
**** | The estimated total U.S. prescription change for the retail and mail order channels are calculated based on Next-Generation Prescription Services (NGPS) version 2.0 data on a weighted-average basis. NGPS data is provided by IMS Health, a supplier of market research for the pharmaceutical industry. The weighted-average basis reflects the fact that mail order prescriptions include a greater volume of product supplied compared to retail prescriptions, which on average are 90 days for mail order and 30 days for retail. The calculation is derived by multiplying NGPS mail order prescription data by a factor that approximates three and adding to this the NGPS retail prescriptions. |
***** | Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. The change in U.S. total prescriptions growth for the Sustiva Franchise includes both branded Sustiva and Atripla prescription units. |
BRISTOL-MYERS SQUIBB COMPANY
INTERNATIONAL* NET SALES BY PRODUCT
QUARTERLY SALES TREND ANALYSIS
($ in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | 2006 | | 2007 | | % Change | |
| | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | 1st Qtr | | 2nd Qtr | | 6 Months | | 3rd Qtr | | 9 Months | | 4th Qtr | | Year | | Qtr vs. Qtr | | | YTD vs. YTD | |
Total Company | | $ | 2,038 | | $ | 2,065 | | $ | 4,103 | | $ | 1,984 | | $ | 6,087 | | $ | 2,098 | | $ | 8,185 | | $ | 1,971 | | | | | | | | | | | | | | -3 | % | | -3 | % |
| | | | | | | | | | | | | | | | |
PHARMACEUTICALS | | | 1,624 | | | 1,654 | | | 3,278 | | | 1,535 | | | 4,813 | | | 1,631 | | | 6,444 | | | 1,513 | | | | | | | | | | | | | | -7 | % | | -7 | % |
| | | | | | | | | | | | | | | | |
Cardiovascular | | | 576 | | | 577 | | | 1,153 | | | 487 | | | 1,640 | | | 477 | | | 2,117 | | | 430 | | | | | | | | | | | | | | -25 | % | | -25 | % |
Plavix | | | 136 | | | 157 | | | 293 | | | 156 | | | 449 | | | 153 | | | 602 | | | 151 | | | | | | | | | | | | | | 11 | % | | 11 | % |
Pravachol | | | 234 | | | 195 | | | 429 | | | 119 | | | 548 | | | 96 | | | 644 | | | 78 | | | | | | | | | | | | | | -67 | % | | -67 | % |
Avapro/ Avalide | | | 94 | | | 113 | | | 207 | | | 118 | | | 325 | | | 125 | | | 450 | | | 107 | | | | | | | | | | | | | | 14 | % | | 14 | % |
Coumadin | | | 8 | | | 9 | | | 17 | | | 8 | | | 25 | | | 9 | | | 34 | | | 8 | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
Virology | | | 209 | | | 254 | | | 463 | | | 240 | | | 703 | | | 253 | | | 956 | | | 271 | | | | | | | | | | | | | | 30 | % | | 30 | % |
Reyataz | | | 88 | | | 114 | | | 202 | | | 104 | | | 306 | | | 111 | | | 417 | | | 120 | | | | | | | | | | | | | | 36 | % | | 36 | % |
Sustiva Franchise**** | | | 67 | | | 78 | | | 145 | | | 73 | | | 218 | | | 78 | | | 296 | | | 82 | | | | | | | | | | | | | | 22 | % | | 22 | % |
Baraclude | | | 2 | | | 5 | | | 7 | | | 8 | | | 15 | | | 18 | | | 33 | | | 28 | | | | | | | | | | | | | | | *** | | | *** |
| | | | | | | | | | | | | | | | |
Oncology | | | 202 | | | 214 | | | 416 | | | 198 | | | 614 | | | 199 | | | 813 | | | 173 | | | | | | | | | | | | | | -14 | % | | -14 | % |
Erbitux | | | 2 | | | — | | | 2 | | | 2 | | | 4 | | | 2 | | | 6 | | | 2 | | | | | | | | | | | | | | — | | | — | |
Taxol | | | 143 | | | 145 | | | 288 | | | 135 | | | 423 | | | 128 | | | 551 | | | 107 | | | | | | | | | | | | | | -25 | % | | -25 | % |
Sprycel | | | — | | | — | | | — | | | — | | | — | | | 3 | | | 3 | | | 11 | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
Affective (Psychiatric) Disorders | | | 86 | | | 90 | | | 176 | | | 88 | | | 264 | | | 102 | | | 366 | | | 103 | | | | | | | | | | | | | | 20 | % | | 20 | % |
Abilify** | | | 52 | | | 57 | | | 109 | | | 53 | | | 162 | | | 68 | | | 230 | | | 73 | | | | | | | | | | | | | | 40 | % | | 40 | % |
| | | | | | | | | | | | | | | | |
Immunoscience | | | — | | | — | | | — | | | — | | | — | | | 1 | | | 1 | | | 1 | | | | | | | | | | | | | | — | | | — | |
Orencia | | | — | | | — | | | — | | | — | | | — | | | 1 | | | 1 | | | 1 | | | | | | | | | | | | | | — | | | — | |
| | | | | | | | | | | | | | | | |
Other Pharmaceuticals | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Efferalgan | | | 68 | | | 62 | | | 130 | | | 62 | | | 192 | | | 74 | | | 266 | | | 81 | | | | | | | | | | | | | | 19 | % | | 19 | % |
| | | | | | | | | | | | | | | | |
NUTRITIONALS | | | 318 | | | 300 | | | 618 | | | 315 | | | 933 | | | 323 | | | 1,256 | | | 332 | | | | | | | | | | | | | | 4 | % | | 4 | % |
Enfamil | | | 82 | | | 79 | | | 161 | | | 77 | | | 238 | | | 81 | | | 319 | | | 83 | | | | | | | | | | | | | | 1 | % | | 1 | % |
Enfagrow | | | 67 | | | 59 | | | 126 | | | 69 | | | 195 | | | 67 | | | 262 | | | 72 | | | | | | | | | | | | | | 7 | % | | 7 | % |
| | | | | | | | | | | | | | | | |
OTHER HEALTH CARE | | | 180 | | | 204 | | | 384 | | | 203 | | | 587 | | | 215 | | | 802 | | | 199 | | | | | | | | | | | | | | 11 | % | | 11 | % |
| | | | | | | | | | | | | | | | |
CONVATEC | | | 157 | | | 177 | | | 334 | | | 181 | | | 515 | | | 190 | | | 705 | | | 176 | | | | | | | | | | | | | | 12 | % | | 12 | % |
Ostomy | | | 89 | | | 100 | | | 189 | | | 100 | | | 289 | | | 106 | | | 395 | | | 96 | | | | | | | | | | | | | | 8 | % | | 8 | % |
Wound Therapeutics | | | 68 | | | 73 | | | 141 | | | 77 | | | 218 | | | 80 | | | 298 | | | 75 | | | | | | | | | | | | | | 10 | % | | 10 | % |
| | | | | | | | | | | | | | | | |
MEDICAL IMAGING | | | 23 | | | 27 | | | 50 | | | 22 | | | 72 | | | 25 | | | 97 | | | 23 | | | | | | | | | | | | | | — | | | — | |
Cardiolite | | | 12 | | | 14 | | | 26 | | | 11 | | | 37 | | | 13 | | | 50 | | | 12 | | | | | | | | | | | | | | — | | | — | |
* | This table presents Total Company sales on a legal entity source basis and segment and product sales on a country management reported basis. As a result, the sum of segment sales does not tie to Total Company sales. |
** | Includes alliance revenue from the co-promotional agreement with Otsuka Pharmaceutical Co., Ltd. |
**** | Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of branded Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. Atripla is sold through a joint venture with Gilead Sciences, Inc. |
BRISTOL-MYERS SQUIBB COMPANY
U.S. PHARMACEUTICALS NET SALES
EXCLUDING ESTIMATED IMPACT OF LAUNCH OF GENERIC CLOPIDOGREL BISULFATE
($ in millions)
| | | | | | |
| | 2007 | | 2006 | | % Change |
| | Q1 | | Q1 | | Qtr vs. Qtr |
U.S Pharmaceuticals Net Sales | | | | | | |
U.S Pharmaceuticals Net Sales as Reported | | $1,932 | | $2,064 | | -6% |
Estimated Impact of Launch of Generic Clopidogrel Bisulfate | | 300 to 350 | | — | | — |
U.S Pharmaceuticals Net Sales Excluding the Estimated | | | | | | |
| | | | | | |
Impact of Launch of Generic Clopidogrel Bisulfate | | $2,232 to $2,282 | | $2,064 | | 8% to 11% |
| | | | | | |
BRISTOL-MYERS SQUIBB COMPANY
GROSS MARGIN
EXCLUDING SPECIFIED ITEMS
($ in millions)
| | | | | | | | | | | | | | | | | | | | |
| | 2007 | |
| | Q1 | | | | | | | | | | | �� | TOTAL YEAR | |
Net Sales | | $ | 4,476 | | | | | | | | | | | | | | | $ | 4,476 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Profit | | | | | | | | | | | | | | | | | | | | |
Gross Profit | | $ | 3,084 | | | | | | | | | | | | | | | $ | 3,084 | |
Specified items* | | | 16 | | | | | | | | | | | | | | | | 16 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Profit Excluding Specified Items | | $ | 3,100 | | | | | | | | | | | | | | | $ | 3,100 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Margin % | | | 68.9 | % | | | | | | | | | | | | | | | 68.9 | % |
Specified items* | | | 0.4 | % | | | | | | | | | | | | | | | 0.4 | % |
| | | | | | | | | | | | | | | | | | | | |
Gross Margin Excluding Specified Items | | | 69.3 | % | | | | | | | | | | | | | | | 69.3 | % |
| | | | | | | | | | | | | | | | | | | | |
| |
| | 2006 | |
| | Q1 | | | Q2 | | | Q3 | | | Q4 | | | TOTAL YEAR | |
Net Sales | | $ | 4,676 | | | $ | 4,871 | | | $ | 4,154 | | | $ | 4,213 | | | $ | 17,914 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Profit | | | | | | | | | | | | | | | | | | | | |
Gross Profit | | $ | 3,200 | | | $ | 3,303 | | | $ | 2,689 | | | $ | 2,766 | | | $ | 11,958 | |
Specified items* | | | 46 | | | | 20 | | | | 72 | | | | 29 | | | | 167 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Profit Excluding Specified Items | | $ | 3,246 | | | $ | 3,323 | | | $ | 2,761 | | | $ | 2,795 | | | $ | 12,125 | |
| | | | | | | | | | | | | | | | | | | | |
Gross Margin % | | | | | | | | | | | | | | | | | | | | |
Gross Margin % | | | 68.4 | % | | | 67.8 | % | | | 64.7 | % | | | 65.6 | % | | | 66.8 | % |
Specified items* | | | 1.0 | % | | | 0.4 | % | | | 1.7 | % | | | 0.7 | % | | | 0.9 | % |
| | | | | | | | | | | | | | | | | | | | |
Gross Margin Excluding Specified Items | | | 69.4 | % | | | 68.2 | % | | | 66.4 | % | | | 66.3 | % | | | 67.7 | % |
| | | | | | | | | | | | | | | | | | | | |
* | Please refer to the Specified Item - QTD tab for detail of specified items. |
BRISTOL-MYERS SQUIBB COMPANY
RESEARCH AND DEVELOPMENT EXPENSES
EXCLUDING SPECIFIED ITEMS
($ in millions)
| | | | | | | | | | | | | | | |
| | 2007 |
| | Q1 | | | | | | | | TOTAL YEAR |
Research and Development Expenses | | $ | 807 | | | | | | | | | | | $ | 807 |
Specified items* | | | 80 | | | | | | | | | | | | 80 |
| | | | | | | | | | | | | | | |
Research and Development Expenses Excluding Specified Items | | $ | 727 | | | | | | | | | | | $ | 727 |
| | | | | | | | | | | | | | | |
| |
| | 2006 |
| | Q1 | | Q2 | | Q3 | | Q4 | | TOTAL YEAR |
Research and Development Expenses | | $ | 750 | | $ | 740 | | $ | 756 | | $ | 821 | | $ | 3,067 |
Specified items* | | | 18 | | | 1 | | | 17 | | | 49 | | | 85 |
| | | | | | | | | | | | | | | |
Research and Development Expenses Excluding Specified Items | | $ | 732 | | $ | 739 | | $ | 739 | | $ | 772 | | $ | 2,982 |
| | | | | | | | | | | | | | | |
* | Please refer to the Specified Item - QTD tab for detail of specified items. |
BRISTOL-MYERS SQUIBB COMPANY
EFFECTIVE TAX RATE
EXCLUDING SPECIFIED ITEMS
($ in millions)
| | | | | | | | | | | | | | | | | | | | |
| | 2007 | |
| | Q1 | | | | | | | | | | | | TOTAL YEAR | |
Provision for Income Taxes | | | | | | | | | | | | | | | | | | | | |
Provision for Income Taxes | | $ | 86 | | | | | | | | | | | | | | | $ | 86 | |
Specified items* | | | 79 | | | | | | | | | | | | | | | | 79 | |
| | | | | | | | | | | | | | | | | | | | |
Provision for Income Taxes Excluding Specified Items | | $ | 165 | | | | | | | | | | | | | | | $ | 165 | |
| | | | | | | | | | | | | | | | | | | | |
Earnings Before Minority Interest and Provision for Income Taxes | | $ | 917 | | | | | | | | | | | | | | | $ | 917 | |
Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items | | $ | 1,050 | | | | | | | | | | | | | | | $ | 1,050 | |
| | | | | |
Effective Tax Rate | | | | | | | | | | | | | | | | | | | | |
Effective Tax Rate | | | 9.4 | % | | | | | | | | | | | | | | | 9.4 | % |
Effective Tax Rate Excluding Specified Items | | | 15.7 | % | | | | | | | | | | | | | | | 15.7 | % |
| |
| | 2006 | |
| | Q1 | | | Q2 | | | Q3 | | | Q4 | | | TOTAL YEAR | |
Provision for Income Taxes | | | | | | | | | | | | | | | | | | | | |
Provision/(Benefit) for Income Taxes | | $ | 328 | | | $ | 256 | | | $ | 193 | | | $ | (167 | ) | | $ | 610 | |
Specified items* | | | (49 | ) | | | (3 | ) | | | (34 | ) | | | 196 | | | | 110 | |
| | | | | | | | | | | | | | | | | | | | |
Provision for Income Taxes Excluding Specified Items | | $ | 279 | | | $ | 253 | | | $ | 159 | | | $ | 29 | | | $ | 720 | |
| | | | | | | | | | | | | | | | | | | | |
Earnings/(Loss) Before Minority Interest and Provision for Income Taxes | | $ | 1,193 | | | $ | 1,110 | | | $ | 617 | | | $ | (285 | ) | | $ | 2,635 | |
Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items | | $ | 1,081 | | | $ | 1,120 | | | $ | 670 | | | $ | 425 | | | $ | 3,296 | |
| | | | | |
Effective Tax Rate | | | | | | | | | | | | | | | | | | | | |
Effective Tax Rate | | | 27.5 | % | | | 23.1 | % | | | 31.3 | % | | | 58.6 | % | | | 23.1 | % |
Effective Tax Rate Excluding Specified Items | | | 25.8 | % | | | 22.6 | % | | | 23.7 | % | | | 6.8 | % | | | 21.8 | % |
* | Please refer to the Specified Item - QTD tab for detail of specified items. |
BRISTOL-MYERS SQUIBB COMPANY
EARNINGS BEFORE MINORITY INTEREST AND INCOME TAXES
EXCLUDING SPECIFIED ITEMS
($ in millions)
| | | | | | | | | | | | | | | | | | | | |
| | 2007 | |
| | Q1 | | | | | | | | | | | | TOTAL YEAR | |
Earnings Before Minority Interest and Provision for Income Taxes | | $ | 917 | | | | | | | | | | | | | | | $ | 917 | |
| | | | | |
Specified items: | | | | | | | | | | | | | | | | | | | | |
Upfront and milestone payments | | | 80 | | | | | | | | | | | | | | | | 80 | |
Downsizing and streamlining of worldwide operations | | | 37 | | | | | | | | | | | | | | | | 37 | |
Accelerated depreciation | | | 16 | | | | | | | | | | | | | | | | 16 | |
| | | | | | | | | | | | | | | | | | | | |
Subtotal | | | 133 | | | | | | | | | | | | | | | | 133 | |
| | | | | | | | | | | | | | | | | | | | |
Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items | | $ | 1,050 | | | | | | | | | | | | | | | $ | 1,050 | |
| | | | | | | | | | | | | | | | | | | | |
| |
| | 2006 | |
| | Q1 | | | Q2 | | | Q3 | | | Q4 | | | TOTAL YEAR | |
Earnings / (Loss) Before Minority Interest and Provision for Income Taxes | | $ | 1,193 | | | $ | 1,110 | | | $ | 617 | | | $ | (285 | ) | | $ | 2,635 | |
| | | | | |
Specified items: | | | | | | | | | | | | | | | | | | | | |
Gain on sale of product asset | | | (200 | ) | | | — | | | | — | | | | — | | | | (200 | ) |
Litigation matters | | | 40 | | | | (14 | ) | | | (29 | ) | | | 353 | | | | 350 | |
Insurance recoveries | | | (21 | ) | | | — | | | | (9 | ) | | | (7 | ) | | | (37 | ) |
Downsizing and streamlining of worldwide operations / other | | | 69 | | | | 24 | | | | 91 | | | | 131 | | | | 315 | |
Debt retirement costs | | | — | | | | — | | | | — | | | | 220 | | | | 220 | |
Claim for damages | | | — | | | | — | | | | — | | | | 13 | | | | 13 | |
| | | | | | | | | | | | | | | | | | | | |
Subtotal | | | (112 | ) | | | 10 | | | | 53 | | | | 710 | | | | 661 | |
| | | | | | | | | | | | | | | | | | | | |
Earnings Before Minority Interest and Provision for Income Taxes Excluding Specified Items | | $ | 1,081 | | | $ | 1,120 | | | $ | 670 | | | $ | 425 | | | $ | 3,296 | |
| | | | | | | | | | | | | | | | | | | | |
BRISTOL-MYERS SQUIBB COMPANY
DILUTED EARNINGS PER COMMON SHARE
EXCLUDING SPECIFIED ITEMS
| | | | | | | | | | | | | | | | | | | |
| | 2007 | |
| | Q1 | | | | | | | | | | | TOTAL YEAR * | |
Diluted Earnings per Common Share | | $ | 0.35 | | | | | | | | | | | | | | $ | 0.35 | |
| | | | | |
Specified items: | | | | | | | | | | | | | | | | | | | |
Upfront payments | | | 0.03 | | | | | | | | | | | | | | | 0.03 | |
Downsizing and streamlining of worldwide operations | | | 0.01 | | | | | | | | | | | | | | | 0.01 | |
Accelerated depreciation | | | 0.01 | | | | | | | | | | | | | | | 0.01 | |
Change in estimate for taxes on a prior year specified item | | | (0.02 | ) | | | | | | | | | | | | | | (0.02 | ) |
| | | | | | | | | | | | | | | | | | | |
Subtotal | | | 0.03 | | | | | | | | | | | | | | | 0.03 | |
| | | | | | | | | | | | | | | | | | | |
Diluted Earnings per Common Share Excluding Specified Items | | $ | 0.38 | | | | | | | | | | | | | | $ | 0.38 | |
| | | | | | | | | | | | | | | | | | | |
| |
| | 2006 | |
| | Q1 | | | Q2 | | Q3 | | | Q4 | | | TOTAL YEAR * | |
Diluted Earnings / (Loss) per Common Share | | $ | 0.36 | | | $ | 0.34 | | $ | 0.17 | | | $ | (0.07 | ) | | $ | 0.81 | |
| | | | | |
Specified items: | | | | | | | | | | | | | | | | | | | |
Gain on sale of product asset | | | (0.06 | ) | | | — | | | — | | | | — | | | | (0.06 | ) |
Litigation matters | | | 0.01 | | | | — | | | (0.01 | ) | | | 0.14 | | | | 0.14 | |
Insurance recoveries | | | (0.01 | ) | | | — | | | — | | | | — | | | | (0.01 | ) |
Downsizing and streamlining of worldwide operations / other | | | 0.02 | | | | 0.01 | | | 0.04 | | | | 0.05 | | | | 0.12 | |
Debt retirement costs | | | — | | | | — | | | — | | | | 0.07 | | | | 0.07 | |
Tax item | | | — | | | | — | | | 0.02 | | | | — | | | | 0.02 | |
| | | | | | | | | | | | | | | | | | | |
Subtotal | | | (0.04 | ) | | | 0.01 | | | 0.05 | | | | 0.26 | | | | 0.28 | |
| | | | | | | | | | | | | | | | | | | |
Diluted Earnings per Common Share Excluding Specified Items | | $ | 0.32 | | | $ | 0.35 | | $ | 0.22 | | | $ | 0.19 | | | $ | 1.09 | |
| | | | | | | | | | | | | | | | | | | |
* | quarterly amounts may not add to the annual total due to rounding of individual calculations. |
BRISTOL-MYERS SQUIBB COMPANY
SPECIFIED ITEMS
FOR THE THREE MONTHS ENDED MARCH 31, 2007 AND 2006
($ in millions)
Three months ended March 31, 2007
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | Cost of products sold | | Research and development | | Provision for restructuring, net | | Total | | | | | | | | | | | | |
Upfront payments | | $ | — | | $ | 80 | | $ | — | | $ | 80 | | | | | | | | | | | | | | | | |
Downsizing and streamlining of worldwide operations | | | — | | | — | | | 37 | | | 37 | | | | | | | | | | | | | | | | |
Accelerated depreciation | | | 16 | | | — | | | — | | | 16 | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | $ | 16 | | $ | 80 | | $ | 37 | | | 133 | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Income taxes on items above | | | | | | | | | | | | (40 | ) | | | | | | | | | | | | | | | |
Change in estimate for taxes on a prior year specified item | | | | | | | | | | | | (39 | ) | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Reduction to Net Earnings | | | | | | | | | | | $ | 54 | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | |
Three months ended March 31, 2006 | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | |
| | Cost of products sold | | Research and development | | Sales Force | | Provision for restructuring and other items, net | | | Litigation settlement income | | | Other expense, net | | Gain on sale of product asset | | | Total | |
Litigation Matters: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Insurance recovery | | $ | — | | $ | — | | $ | — | | $ | — | | | $ | (21 | ) | | $ | — | | $ | — | | | $ | (21 | ) |
Commercial litigation | | | — | | | — | | | — | | | — | | | | — | | | | 40 | | | — | | | | 40 | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | — | | | — | | | — | | | — | | | | (21 | ) | | | 40 | | | — | | | | 19 | |
Other: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Accelerated depreciation and asset impairment | | | 46 | | | — | | | 4 | | | — | | | | — | | | | — | | | — | | | | 50 | |
Upfront and milestone payments | | | — | | | 18 | | | — | | | — | | | | — | | | | — | | | — | | | | 18 | |
Downsizing and streamlining of worldwide operations | | | — | | | — | | | — | | | 1 | | | | — | | | | — | | | — | | | | 1 | |
Gain on sale of product asset | | | — | | | — | | | — | | | — | | | | — | | | | — | | | (200 | ) | | | (200 | ) |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | $ | 46 | | $ | 18 | | $ | 4 | | $ | 1 | | | $ | (21 | ) | | $ | 40 | | $ | (200 | ) | | | (112 | ) |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Income taxes on items above | | | | | | | | | | | | | | | | | | | | | | | | | | | 48 | |
Minority interest, net of taxes | | | | | | | | | | | | | | | | | | | | | | | | | | | (13 | ) |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Increase to Net Earnings | | | | | | | | | | | | | | | | | | | | | | | | | | $ | (77 | ) |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | |
BRISTOL-MYERS SQUIBB COMPANY
SELECT BALANCE SHEET INFORMATION
($ in millions)
| | | | | | | | | | | | | | | | | | | | | | | | | |
| | March 31, 2006 | | June 30, 2006 | | September 30, 2006 | | December 31, 2006 | | | March 31, 2007 | | June 30, 2007 | | September 30, 2007 | | December 31, 2007 |
Cash, cash equivalents and marketable debt securities | | $ | 5,281 | | $ | 5,357 | | $ | 5,505 | | $ | 4,013 | | | $ | 4,012 | | $ | — | | $ | — | | $ | — |
Short-term borrowings | | | 234 | | | 189 | | | 630 | | | 187 | | | | 241 | | | — | | | — | | | — |
Long-term debt | | | 8,278 | | | 8,239 | | | 7,837 | | | 7,248 | | | | 7,132 | | | — | | | — | | | — |
| | | | | | | | | | | | | | | | | | | | | | | | | |
Net debt | | $ | 3,231 | | $ | 3,071 | | $ | 2,962 | | $ | 3,422 | | | $ | 3,361 | | $ | — | | $ | — | | $ | — |
| | | | | | | | | | | | | | | | | | | | | | | | | |
Receivables, net of allowances | | $ | 3,236 | | $ | 3,326 | | $ | 2,945 | | $ | 3,247 | | | $ | 3,381 | | $ | — | | $ | — | | $ | — |
| | | | | | | | |
Stockholders’ equity | | | 11,556 | | | 11,712 | | | 11,589 | | | 9,991 | (1) | | | 10,261 | | | — | | | — | | | — |
| | | | | | | | |
Capital expenditures and capitalized software (for the quarter ended) | | | 202 | | | 160 | | | 199 | | | 224 | | | | 202 | | | | | | | | | |
(1) | Includes the impact of the adoption of SFAS 158, “Employers’ Accounting for Defined Benefit Pension and Other Postretirement Plans - an amendment of FASB Statements No. 87, 88, 106 and 132(R)” |
BRISTOL-MYERS SQUIBB COMPANY
2007 FULL YEAR PROJECTED DILUTED EPS
EXCLUDING PROJECTED SPECIFIED ITEMS
| | | | |
| | Full Year 2007 | |
Projected Diluted Earnings per Common Share | | $ | 1.24 to $1.34 | |
Projected Specified Items: | | | | |
Upfront and milestone payments | | | 0.05 | |
Downsizing and streamlining of worldwide operations | | | 0.03 | |
Change in estimate for taxes on a prior year specified item | | | (0.02 | ) |
| | | | |
Total | | | 0.06 | |
| | | | |
Projected Diluted Earnings per Common Share Excluding Specified Items | | $ | 1.30 to $1.40 | |
| | | | |
Gross Margin/Research and Development/Tax Rate Projections Excluding Specified Items
Gross margin on a GAAP basis for the three months ended March 31, 2007 was 68.9%, which included specified items of $16 million and had a 0.4% adverse impact on gross margin in aggregate. On a non-GAAP basis, for the three months ended March 31, 2007 gross margin was 69.3%. On a non-GAAP basis, based on historical trends in 2006 and the first quarter of 2007 the Company projects gross margin for the full year 2007 to be at least 100 basis points higher than 2006. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on gross margin. See Gross Margin non comparable tab.
Research and development expenses on a GAAP basis for the three months ended March 31, 2007 were $807 million, which included specified items of $80 million. On a non-GAAP basis, for the three months ended March 31, 2007 research and development expenses were $727 million. On a non-GAAP basis, based on historical trends in 2006 and the first quarter of 2007 the Company projects research and development expenses for the full year 2007 to increase in the mid to upper single digit range compared to 2006. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on research and development. See R&D non comparable tab.
The effective tax rate on a GAAP basis for the three months ended March 31, 2007 was 9.4%, which included specified items of $79 million in the tax provision, and had a 6.3% favorable impact on the effective tax rate in aggregate. On a non-GAAP basis, the three months ended March 31, 2007 effective tax rate was 15.7%. On a non-GAAP basis, based on historical trends in 2006 and the first quarter of 2007 the Company projects effective tax rate for the full year 2007 to be in the 20% range. There is no reasonably accessible or reliable comparable GAAP measure for this forward-looking information on the tax rate. See Tax Rate non comparable tab.
The GAAP results for the full year 2007 would include specified items that may occur and impact results. These specified items could include charges and recoveries relating to significant legal proceedings, debt retirement costs and other charges related to new transactions, upfront and milestone payments, copromotion or alliance charges and charges for in-process research and development related to new external development transactions, gains or losses from asset disposals, restructuring activities and significant tax events. For a fuller discussion of certain of the litigation and other matters that could impact full year GAAP results, as well as the use of non-GAAP financial information, see Bristol-Myers Squibb Company Reports Financial Results For The First Quarter of 2007, April 26, 2007, including “2007 Guidance” and “Use of Non-GAAP Financial Information” therein.
BRISTOL-MYERS SQUIBB COMPANY
ESTIMATED MONTHS ON HAND OF TOP 15 U.S. PHARMACEUTICAL PRODUCTS
IN THE U.S. WHOLESALER DISTRIBUTION CHANNEL
The following tables sets forth, for each of the Company’s top 15 pharmaceutical products (based on 2006 annual net sales) sold by the Company’s U.S. Pharmaceuticals business, the U.S. Pharmaceuticals net sales and the estimated number of months on hand of the applicable product in the U.S. wholesaler distribution channel for the quarters ended March 31, 2007 and 2006 and December 31, 2006 and 2005.
| | | | | | | | | | | | | | | | | | | | |
| | March 31, 2007 | | December 31, 2006 | | March 31, 2006 | | December 31, 2005 |
| | Net Sales | | Months on Hand | | Net Sales | | Months on Hand | | Net Sales | | Months on Hand | | Net Sales | | Months on Hand |
| | (Dollars in Millions) | | | | (Dollars in Millions) | | | | (Dollars in Millions) | | | | (Dollars in Millions) | | |
Abilify (total revenue) | | $ | 293 | | 0.4 | | $ | 294 | | 0.5 | | $ | 231 | | 0.5 | | $ | 175 | | 0.6 |
Avapro/Avalide | | | 163 | | 0.4 | | | 182 | | 0.5 | | | 139 | | 0.4 | | | 168 | | 0.6 |
Baraclude | | | 17 | | 0.6 | | | 18 | | 0.7 | | | 9 | | 1.0 | | | 4 | | 0.7 |
Coumadin | | | 38 | | 0.7 | | | 48 | | 0.8 | | | 47 | | 0.6 | | | 50 | | 0.8 |
Erbitux(a) | | | 158 | | 0.3 | | | 165 | | 0.4 | | | 136 | | — | | | 121 | | — |
Glucophage Franchise | | | 21 | | 0.6 | | | 16 | | 0.7 | | | 25 | | 0.7 | | | 29 | | 0.7 |
Kenalog | | | 18 | | 0.5 | | | 24 | | 0.8 | | | 23 | | 0.7 | | | 23 | | 0.9 |
Orencia(b) | | | 40 | | 0.3 | | | 31 | | 0.4 | | | 5 | | 0.9 | | | — | | — |
Paraplatin | | | 5 | | 13.8 | | | 6 | | 5.8 | | | 7 | | 1.2 | | | 5 | | 0.9 |
Plavix | | | 787 | | 0.6 | | | 343 | | 0.6 | | | 850 | | 0.4 | | | 906 | | 0.6 |
Pravachol | | | 57 | | 0.6 | | | 50 | | 0.6 | | | 302 | | 0.4 | | | 366 | | 0.6 |
Reyataz | | | 143 | | 0.7 | | | 144 | | 0.7 | | | 119 | | 0.6 | | | 110 | | 0.5 |
Sprycel | | | 10 | | 0.7 | | | 11 | | 1.4 | | | — | | — | | | — | | — |
Sustiva Franchise (c) (total revenue) | | | 144 | | 0.7 | | | 144 | | 0.7 | | | 108 | | 0.5 | | | 102 | | 0.6 |
Zerit | | | 12 | | 0.6 | | | 19 | | 0.9 | | | 19 | | 0.7 | | | 21 | | 0.8 |
For all products other than Erbitux and Orencia, the Company determines the above months on hand estimates by dividing the estimated amount of the product in the U.S. wholesaler distribution channel by the estimated amount of out-movement of the product from the U.S. wholesaler distribution channel over a period of 31 days, all calculated as described below. Factors that may influence the Company’s estimates include generic competition, seasonality of products, wholesaler purchases in light of increases in wholesaler list prices, new product launches, new warehouse openings by wholesalers and new customer stockings by wholesalers. In addition, such estimates are calculated using third-party data, which represent their own record-keeping processes and as such, may also reflect estimates.
Estimates of product in the wholesaler distribution channel and out-movement are based on weekly information received directly from third-parties, and excludes any inventory held by intermediaries such as retailers and hospitals, and excludes goods in transit to such wholesalers. The Company determines the amount of out-movement of a product over a period of 31 days by using the most recent out-movement of a product as provided by these third parties, adjusted to reflect the Company’s estimate of goods in transit to these wholesalers. The Company estimates the amount of goods in transit by using information provided by these wholesalers with respect to their open orders and the Company’s records of sales to these wholesalers with respect to such open orders.
(a) In the first and second quarter of 2006, the Company sold Erbitux to intermediaries (such as wholesalers and specialty oncology distributors) and shipped Erbitux directly to the end-users of the product who are the customers of those intermediaries. Beginning in the third quarter of 2006, the Company expanded its distribution model to include two distributors who then held Erbitux inventory. One additional distributor was added for Erbitux in the first quarter of 2007. The Company recognizes revenue upon such shipment consistent with its revenue recognition policy. The above estimate of months on hand was calculated by dividing the inventories of Erbitux held by the distributors for their own accounts as reported by the distributors as of the end of the quarter by the out-movements of the product reported by the distributors over the last 31 day period. The inventory levels reported by the distributors are a product of their record-keeping process.
(b) Orencia was launched in February 2006. From launch through the second quarter, the Company distributed Orencia through an exclusive distribution arrangement with a single distributor. Following approval of the supplemental Biologics License Application (sBLA) that allows a third party to manufacture Orencia at an additional site, the exclusive distribution arrangement terminated on July 17, 2006 and the Company expanded its distribution network for ORENCIA to multiple distributors. The above estimates of months on hand was calculated by dividing the inventories of Orencia held by these distributors at the end of the quarter by the out-movement of the product over the last 31 day period, as reported by these distributors. The inventory on hand and out-movements reported by these distributors are a product of the distributors’ own record-keeping process.
(c) Beginning in the third quarter of 2006, the Sustiva Franchise includes sales of Sustiva, as well as revenue of bulk efavirenz included in the combination therapy, Atripla. The estimated months on hand of the product in the U.S. wholesale distribution channel only include branded Sustiva inventory.