Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consentto the incorporation by reference, in the Prospectus constituting a part of this Registration Statement on Form S-3,of our reports dated March 2, 2017 relating to the consolidated financial statementsand the effectiveness of internal control over financial reporting of AcelRx Pharmaceuticals, Inc. appearing in the Company’s Annual Report on Form 10-K forthe year ended December 31, 2016.
We also consent to the reference to us under the caption “Experts” in the Prospectus.
/s/ OUM & CO. LLP
San Francisco, California
June 5, 2017
