| Document And Entity Information | Jan. 17, 2024 |
| Document Information [Line Items] | |
| Entity, Registrant Name | TALPHERA, INC. |
| Document, Type | 8-K |
| Document, Period End Date | Jan. 17, 2024 |
| Entity, Incorporation, State or Country Code | DE |
| Entity, File Number | 001-35068 |
| Entity, Tax Identification Number | 41-2193603 |
| Entity, Address, Address Line One | 1850 Gateway Drive, Suite 175 |
| Entity, Address, City or Town | San Mateo |
| Entity, Address, State or Province | CA |
| Entity, Address, Postal Zip Code | 94404 |
| City Area Code | 650 |
| Local Phone Number | 216-3500 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | TLPH |
| Security Exchange Name | NASDAQ |
| Entity, Emerging Growth Company | false |
| Amendment Flag | false |
| Entity, Central Index Key | 0001427925 |
