| Cover | Apr. 05, 2023 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Apr. 05, 2023 |
| Entity File Number | 001-36019 |
| Entity Registrant Name | TONIX PHARMACEUTICALS HOLDING CORP. |
| Entity Central Index Key | 0001430306 |
| Entity Tax Identification Number | 26-1434750 |
| Entity Incorporation, State or Country Code | NV |
| Entity Address, Address Line One | 26 Main Street |
| Entity Address, City or Town | Chatham |
| Entity Address, State or Province | NJ |
| Entity Address, Postal Zip Code | 07928 |
| City Area Code | (862) |
| Local Phone Number | 904-8182 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | TNXP |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
