Agios Pharmaceuticals (AGIO) S-8 Registration of securities for employees

Exhibit 107

Calculation of Filing Fee Tables

Form S-8

(Form Type)

Agios Pharmaceuticals, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1—Newly Registered Securities

Security Type	Security Class Title	Fee Calculation  Rule	Amount Registered (1)	Proposed Maximum  Offering Price Per Unit	Maximum  Aggregate  Offering Price	Fee Rate	Amount of Registration Fee
Equity	Common Stock, $0.001 par value per  share	Other	135,682 shares (2)	$27.53 (5)	$3,735,325.46 (5)	$110.20 per $1,000,000	$411.64
Equity	Common Stock, $0.001 par value per  share	Other	25,426 shares (3)	$26.77 (6)	$680,654.02 (6)	$110.20 per $1,000,000	$75.01
Equity	Common Stock, $0.001 par value per  share	Other	10,897 shares (4)	$26.77 (6)	$291,712.69 (6)	$110.20 per $1,000,000	$32.15
Total Offering Amounts					$4,707,692.17		$518.80
Total Fee Offsets							$0
Net Fee Due							$518.80

(1) In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

(2) Consists of 135,682 shares issuable under an inducement stock option award granted to Tsveta Milanova, the registrant’s Chief Commercial Officer, on January 3, 2023, in accordance with Nasdaq Listing Rule 5635(c)(4), as an inducement material to Ms. Milanova’s entering into employment with the registrant.

(3) Consists of 25,426 shares issuable under an inducement restricted stock unit award granted to Ms. Milanova, the registrant’s Chief Commercial Officer, on January 3, 2023, in accordance with Nasdaq Listing Rule 5635(c)(4), as an inducement material to Ms. Milanova’s entering into employment with the registrant.

(4) Consists of 10,897 shares issuable under an inducement performance stock unit award granted to Ms. Milanova, the registrant’s Chief Commercial Officer, on January 3, 2023, in accordance with Nasdaq Listing Rule 5635(c)(4), as an inducement material to Ms. Milanova’s entering into employment with the registrant.

(5) Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457(h) of the Securities Act of 1933, as amended. The proposed maximum offering price per share and the maximum aggregate offering price are calculated on the basis of the exercise price of the options outstanding under the inducement stock option award.

(6) Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low sale prices of the Registrant’s Common Stock as reported on the Nasdaq Global Select Market on December 27, 2022.