| (i) | Mr. Bancel directly owns 5,429,839 shares of Common Stock and 9,339,775 shares issuable to Mr. Bancel upon exercise of share options exercisable within 60 days after December 31, 2023. In addition, Mr. Bancel may be deemed to have voting and dispositive power over (i) 6,564,880 shares of Common Stock directly owned by OCHA LLC, of which Mr. Bancel is the majority unit holder and sole managing member, and (ii) 9,050,372 shares of Common Stock directly owned by Boston Biotech Ventures, LLC, of which Mr. Bancel is the majority unit holder and the sole managing member. Mr. Bancel disclaims Section 13(d) beneficial ownership over all shares held by OCHA LLC and Boston Biotech Ventures, LLC, and this report shall not be deemed an admission that Mr. Bancel is the beneficial owner of such shares for Section 13(d) or any other purpose. The aggregate of 30,384,866 shares of Common Stock with respect to which Mr. Bancel may be deemed to have voting and dispositive power represents approximately 7.8% of the outstanding shares of Common Stock. |