SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
SCHEDULE 13G
UNDERTHE SECURITIES EXCHANGE ACTOF 1934
(AMENDMENT NO. )*
Proteostasis Therapeutics, Inc.
(Name of Issuer)
Common Stock, par value $0.001 per share
(Title of Class of Securities)
74373B 109
(CUSIP Number)
February 17, 2016
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
¨ Rule 13d-1(b)
x Rule 13d-1(c)
¨ Rule 13d-1(d)
| * | The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. |
The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,see theNotes).
| CUSIP No. 74373B 109 | 13G | Page 2 of 6 Pages |
| 1. | Names of Reporting Persons
Novartis Bioventures Ltd. | |||||
| 2. | Check the Appropriate Box if a Member of a Group (see instructions)
(a) ¨ (b) ¨ | |||||
| 3. | SEC USE ONLY
| |||||
| 4. | Citizenship or Place of Organization
Bermuda | |||||
Number of Shares Beneficially Owned by Each Reporting Person With: | 5. | Sole Voting Power
0 | ||||
| 6. | Shared Voting Power
1,873,791 | |||||
| 7. | Sole Dispositive Power
0 | |||||
| 8. | Shared Dispositive Power
1,873,791 | |||||
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person
1,873,791 | |||||
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)
¨ | |||||
| 11. | Percent of Class Represented by Amount in Row 9
9.805% | |||||
| 12. | Type of Reporting Person (see instructions)
CO | |||||
| CUSIP No. 74373B 109 | 13G | Page 3 of 6 Pages |
| 1. | Names of Reporting Persons
Novartis AG | |||||
| 2. | Check the Appropriate Box if a Member of a Group (see instructions)
(a) ¨ (b) ¨ | |||||
| 3. | SEC USE ONLY
| |||||
| 4. | Citizenship or Place of Organization
Switzerland | |||||
Number of Shares Beneficially Owned by Each Reporting Person With: | 5. | Sole Voting Power
0 | ||||
| 6. | Shared Voting Power
1,873,791 | |||||
| 7. | Sole Dispositive Power
0 | |||||
| 8. | Shared Dispositive Power
1,873,791 | |||||
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person
1,873,791 | |||||
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (see instructions)
¨ | |||||
| 11. | Percent of Class Represented by Amount in Row 9
9.805% | |||||
| 12. | Type of Reporting Person (see instructions)
CO | |||||
| Item 1(a). | Name of Issuer:
Proteostasis Therapeutics, Inc. | |
| Item 1(b). | Address of Issuer’s Principal Executive Offices:
200 Technology Square, Fourth Floor, Cambridge, MA 02139. | |
| Item 2(a). | Name of Person Filing:
This statement is filed on behalf of the following persons with respect to shares of common stock of the Issuer:
(i) Novartis Bioventures Ltd., a Bermuda corporation, with respect to shares held by it; and
(ii) Novartis AG, a Switzerland corporation, as the publicly owned parent of Novartis Bioventures Ltd., with respect to the shares held by Novartis Bioventures Ltd
The foregoing persons are hereinafter referred to collectively as the “Reporting Persons.” | |
| Item 2(b). | Address of Principal Business Office or, if none, Residence:
The address of the principal business office of Novartis Bioventures Ltd. is 131 Front Street, Hamilton, Bermuda HM12. The address of the principal business office of Novartis AG is Lichtstrasse 35, 4056 Basel, Switzerland. | |
| Item 2(c). | Citizenship:
Novartis Bioventures Ltd. is a corporation organized under the laws of Bermuda and is an indirect wholly-owned subsidiary of Novartis AG.
Novartis AG is a corporation organized under the laws of Switzerland and is the publicly owned parent of Novartis Bioventures Ltd.. | |
| Item 2(d). | Title of Class of Securities:
Common Stock, par value $0.001 per share (“Common Stock”). | |
| Item 2(e). | CUSIP Number:
74373B 109 | |
| Item 3. | If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a: | |
| (a) | ¨ Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o); | |
| (b) | ¨ Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c); | |
| (c) | ¨ Insurance company as defined in section 3(a)19) of the Act (15 U.S.C. 78c); | |
| (d) | ¨ Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8); | |
| (e) | ¨ An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E); | |
| (f) | ¨ An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F); | |
| (g) | ¨ A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G); | |
| (h) | ¨ A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813); | |
| (i) | ¨ A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3); | |
| (j) | ¨ A non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J); | |
| (k) | ¨ Group, in accordance with §240.13d–1(b)(1)(ii)(K). | |
| If filing as a non-U.S. institution in accordance with §240.13d–1(b)(1)(ii)(J), please specify the type of institution: | ||
| Item 4. | Ownership |
| (a) | Amount Beneficially Owned: |
Novartis Bioventures Ltd. is the record owner of1,873,791 shares of Common Stock of the Issuer. As the indirect parent of Novartis Bioventures, Ltd, Novartis AG may be deemed to beneficially own these securities.
| (b) | Percent of Class: |
9.805%
| (c) | Number of shares as to which the person has: |
| (i) | Sole power to vote or to direct the vote: Not applicable |
| (ii) | Shared power to vote or to direct the vote:1,873,791 |
| (iii) | Sole power to dispose or to direct the disposition of: Not applicable |
| (iv) | Shared power to dispose or to direct the disposition of:1,873,791 |
| Item 5. | Ownership of 5 Percent or Less of a Class |
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following¨.
| Item 6. | Ownership of More than 5 Percent on Behalf of Another Person |
Not Applicable
| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. |
Not Applicable
| Item 8. | Identification and Classification of Members of the Group |
Not Applicable
| Item 9. | Notice of Dissolution of a Group |
Not Applicable
| Item 10. | Certification |
Each of the Reporting Persons hereby makes the following certification:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.
Signature
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Date: February 23, 2016
| NOVARTIS BIOVENTURES LTD. | ||
/s/ Simon Zivi | ||
| Name: | Simon Zivi | |
| Title: | Chairman | |
/s/ Laurieann Chaikowsky | ||
| Name: | Laurieann Chaikowsky | |
| Title: | Authorized Signatory | |
| NOVARTIS AG | ||
/s/ Simon Zivi | ||
| Name: | Simon Zivi | |
| Title: | Authorized Signatory | |
/s/ Laurieann Chaikowky | ||
| Name: | Laurieann Chaikowsky | |
| Title: | Authorized Signatory | |
INDEX EXHIBIT
SCHEDULE 13G
Exhibit Number | Exhibit Description | |
| 99.1 | Evidence of Signature Authority | |
| 99.2 | Power of Attorney | |
| 99.3 | Joint Filing Agreement | |