| Document and Entity Information | Oct. 27, 2022 |
| Cover [Abstract] | |
| Security Exchange Name | NASDAQ |
| Amendment Flag | false |
| Entity Central Index Key | 0001445283 |
| Document Type | 8-K |
| Document Period End Date | Oct. 27, 2022 |
| Entity Registrant Name | YUMANITY THERAPEUTICS, INC. |
| Entity Incorporation State Country Code | DE |
| Entity File Number | 001-37695 |
| Entity Tax Identification Number | 20-8436652 |
| Entity Address, Address Line One | 40 Guest Street |
| Entity Address, Address Line Two | Suite 4410 |
| Entity Address, City or Town | Boston |
| Entity Address, State or Province | MA |
| Entity Address, Postal Zip Code | 02135 |
| City Area Code | (617) |
| Local Phone Number | 409-5300 |
| Written Communications | true |
| Soliciting Material | false |
| Pre Commencement Tender Offer | false |
| Pre Commencement Issuer Tender Offer | false |
| Security 12b Title | Common Stock, par value $0.001 per share |
| Trading Symbol | YMTX |
| Entity Emerging Growth Company | false |
