Item 1. Security and Issuer.
This statement relates to the common stock, $.0001 par value (the “Common Stock”) of Epizyme, Inc. (the “Issuer”) having its principal executive office at 400 Technology Square, Cambridge, MA 02139.
Item 2. Identity and Background.
This statement is being filed by:
(a) New Enterprise Associates 13, L.P. (“NEA 13”);
(b) NEA Partners 13, L.P. (“NEA Partners 13”), which is the sole general partner of NEA 13; and NEA 13 GP, LTD (“NEA 13 LTD” and, together with NEA Partners 13, the “Control Entities”), which is the sole general partner of NEA Partners 13; and
(c) Michael James Barrett (“Barrett”), Peter J. Barris (“Barris”), Forest Baskett (“Baskett”), Ryan D. Drant (“Drant”), Patrick J. Kerins (“Kerins”), Krishna S. Kolluri (“Kolluri”), David M. Mott (“Mott”), Scott D. Sandell (“Sandell”), Ravi Viswanathan (“Viswanathan”) and Harry R. Weller (“Weller”) (together, the “Directors”). The Directors are the directors of NEA 13 LTD.
The persons named in this Item 2 are referred to individually herein as a “Reporting Person” and collectively as the “Reporting Persons.”
The address of the principal business office of NEA 13 and each Control Entity is New Enterprise Associates, 1954 Greenspring Drive, Suite 600, Timonium, MD 21093. The address of the principal business office of each of Barrett, Barris, Drant, Kerins, Mott and Weller is New Enterprise Associates, 5425 Wisconsin Avenue, Suite 800, Chevy Chase, MD 20815. The address of the principal business office of Baskett, Kolluri, Sandell and Viswanathan is New Enterprise Associates, 2855 Sand Hill Road, Menlo Park, California 94025.
The principal business of NEA 13 is to invest in and assist growth-oriented businesses located principally in the United States. The principal business of NEA Partners 13 is to act as the sole general partner of NEA 13. The principal business of NEA 13 LTD is to act as the sole general partner of NEA Partners 13. The principal business of each of the Directors is to manage the Control Entities, NEA 13 and a number of affiliated partnerships with similar businesses.
During the five years prior to the date hereof, none of the Reporting Persons has been convicted in a criminal proceeding or has been a party to a civil proceeding ending in a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.
NEA 13 and NEA Partners 13 are exempt limited partnerships organized under the laws of the Cayman Islands. NEA 13 LTD is an exempted company organized under the laws of the Cayman Islands. Each of the Directors is a United States citizen.
Item 3. Source and Amount of Funds or Other Consideration.
On November 14, 2013 and November 15, 2013, Growth Equity Opportunities Fund II, LLC (“GEO”) purchased 406,500 shares of Common Stock (the “GEO Shares”) in a series of open-market transactions for an aggregate purchase price of $8,006,099. NEA 13 is the sole member of GEO.
On May 30, 2013, the Registration Statement on Form S-1 filed with the Securities and Exchange Commission by the Issuer (File No. 333-187982) in connection with its initial public offering of 5,142,000 shares of Common Stock of the Issuer (the “IPO”) was declared effective. The closing of the IPO took place on June 5, 2013, and at such closing NEA 13 purchased an aggregate of 400,000 shares of Common Stock at the IPO price of $15.00 per share. In addition, immediately prior to the closing of the IPO, the 16,899,721 shares of Series B Preferred Stock (“Series B Stock”) held by NEA 13 automatically converted into 5,633,240 shares of Common Stock of the Issuer. Prior to the IPO, the Series B Stock was purchased from the Issuer in a series of private transactions for an aggregate purchase price of $26,019.796. NEA 13 now holds a total of 6,033,240 shares of the Issuer’s Common Stock (the “NEA 13 Shares”).
The working capital of GEO was the source of the funds for the purchase of the GEO Shares and the working capital of NEA 13 was the source of the funds for the purchase of the NEA 13 Shares. No part of the purchase price of the GEO Shares or the NEA 13 Shares was represented by funds or other consideration borrowed or otherwise obtained for the purpose of acquiring, holding, trading or voting the GEO Shares or the NEA 13 Shares.
Item 4. Purpose of Transaction.
GEO and NEA 13 acquired the GEO Shares and NEA 13 Shares, respectively, for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, GEO, NEA 13 and other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in:
| (a) | The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; |
| (b) | An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; |
| (c) | A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; |
| (d) | Any change in the present board of directors or management of the Issuer, including any plans or proposals to change the number or term of directors or to fill any existing vacancies on the board; |
| (e) | Any material change in the present capitalization or dividend policy of the Issuer; |
| (f) | Any other material change in the Issuer’s business or corporate structure; |
| (g) | Changes in the Issuer’s charter, bylaws or instruments corresponding thereto or other actions which may impede the acquisition of control of the Issuer by any person; |
| (h) | Causing a class of securities of the Issuer to be delisted from a national securities exchange or to cease to be authorized to be quoted in an inter-dealer quotation system of a registered national securities association; |
| (i) | A class of equity securities of the Issuer becoming eligible for termination of registration pursuant to Section 12(g)(4) of the Securities Exchange Act of 1934; or |
| (j) | Any action similar to any of those enumerated above. |
Item 5. | Interest in Securities of the Issuer. |
GEO is the record owner of the GEO Shares. NEA 13 is the record owner of the NEA 13 Shares and, as the sole member of GEO, may be deemed to beneficially own the GEO Shares. As the sole general partner of NEA 13, NEA Partners 13 may be deemed to own beneficially the GEO Shares and the NEA 13 Shares (the “Total NEA Shares”). As the sole general partner of NEA Partners 13, NEA 13 LTD may be deemed to own beneficially the Total NEA Shares. As members of NEA 13 LTD, each of the Directors may be deemed to own beneficially the Total NEA Shares.
Each Reporting Person disclaims beneficial ownership of the Total NEA Shares other than those shares which such person owns of record.
The percentage of outstanding Common Stock of the Issuer which may be deemed to be beneficially owned by each Reporting Person is set forth on Line 13 of such Reporting Person’s cover sheet. Such percentage was calculated based on the 28,419,288 shares of Common Stock reported to be outstanding as of October 18, 2013 in the Issuer’s Form 10-Q filed on October 23, 2013.
| (b) | Regarding the number of shares as to which such person has: |
| (i) | sole power to vote or to direct the vote: See line 7 of cover sheets |
| (ii) | shared power to vote or to direct the vote: See line 8 of cover sheets |
| (iii) | sole power to dispose or to direct the disposition: See line 9 of cover sheets. |
| (iv) | shared power to dispose or to direct the disposition: See line 10 of cover sheets |
| (c) | Except as set forth in Item 3 above, none of the Reporting Persons has effected any transaction in the Common Stock during the last 60 days. |
| (d) | No other person is known to have the right to receive or the power to direct the receipt of dividends from, or any proceeds from the sale of, Shares beneficially owned by any of the Reporting Persons. |
Item 6. | Contracts, Arrangements, Undertakings or Relationships with Respect to Securities of the Issuer. |
GEO and NEA 13 have entered into a lock-up agreement with the underwriters of the IPO pursuant to which GEO and NEA 13 have generally agreed, subject to certain exceptions, not to dispose of or hedge any shares of Common Stock or securities convertible into or exchangeable or exercisable for shares of Common Stock for a period of 180 days from May 30, 2013 without the prior written consent of Citigroup.
Item 7. Material to be Filed as Exhibits.
| Exhibit 1 – Agreement regarding filing of joint Schedule 13D. |
Exhibit 2 – Power of Attorney regarding filings under the Securities Exchange Act of 1934, as amended.