Auspex Pharmaceuticals Form 4 Change in insider ownership

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

CMEA Ventures VII LP

(Last) (First) (Middle)

ONE LETTERMAN DRIVE

BUILDING C, SUITE CM500

(Street)

SAN FRANCISCO CA 94129

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Auspex Pharmaceuticals, Inc. [ ASPX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
04/02/2015

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	04/02/2015		X/K(1)		292,500	D	$29.79	2,478,021	D
Common Stock	04/02/2015		X/K(1)		7,500	D	$29.79	63,589	I	By: CMEA Ventures VII (Parallel) LP

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Call Option (obligation to sell)	$29.79	04/02/2015		X/K(1)			1	04/02/2015	04/02/2015	Common Stock	292,500	$0.00	0	D
Put option (right to sell)	$17.65	04/02/2015		J/K(1)			1	04/02/2015	04/02/2015	Common Stock	292,500	$0.00	0	D
Call Option (obligation to sell	$29.79	04/02/2015		X/K(1)			1	04/02/2015	04/02/2015	Common Stock	7,500	$0.00	0	I	By: CMEA Ventures VII (Parallel) LP
Put option (right to sell	$17.65	04/02/2015		J/K(1)			1	04/02/2015	04/02/2015	Common Stock	7,500	$0.00	0	I	By: CMEA Ventures VII (Parallel) LP

1. Name and Address of Reporting Person^*

CMEA Ventures VII LP

(Last) (First) (Middle)

ONE LETTERMAN DRIVE

BUILDING C, SUITE CM500

(Street)

SAN FRANCISCO CA 94129

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

CMEA VENTURES VII (PARALLEL) LP

(Last) (First) (Middle)

ONE LETTERMAN DRIVE

BUILDING C, SUITE CM500

(Street)

SAN FRANCISCO CA 94129

(City) (State) (Zip)

Explanation of Responses:

1. In connection with the settlement of a call option written by the reporting persons on September 9, 2014, as part of a collar arrangement, the reporting persons delivered to the option holder each share of stock subject to the option. On the same date, the related put option expired unexercised.

Remarks:

	CMEA Ventures VII, L.P. By: CMEA Ventures VII GP, L.P., its General Partner By: CMEA Ventures VII GP, LLC, its General Partner By: /s/ David Collier, Manager	04/06/2015
	David Collier, Manager of CMEA Ventures VII GP, LLC, General Parter of CMEA Ventures VII GP, L.P., General Partner of CMEA Ventures VII (Parallel), LP	04/06/2015
	** Signature of Reporting Person	Date
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