The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AEGLEA BIOTHERAPEUTICS INC | COM | 00773J103 | 4,329 | 550,000 | SH | OTR | 550,000 | 0 | 0 | ||
| AKERO THERAPEUTICS INC | COM | 00973Y108 | 21,453 | 831,495 | SH | OTR | 831,495 | 0 | 0 | ||
| AGENUS INC | COM NEW | 00847G705 | 12,720 | 4,000,000 | SH | OTR | 4,000,000 | 0 | 0 | ||
| ALIGOS THERAPEUTICS INC | COM | 01626L105 | 42,195 | 1,526,048 | SH | OTR | 1,526,048 | 0 | 0 | ||
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 29,340 | 6,000,000 | SH | OTR | 6,000,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 53,684 | 2,325,000 | SH | OTR | 2,325,000 | 0 | 0 | ||
| ANAPTYSBIO INC | COM | 032724106 | 27,950 | 1,300,000 | SH | OTR | 1,300,000 | 0 | 0 | ||
| ARCUS BIOSCIENCES INC | COM | 03969F109 | 54,124 | 2,084,883 | SH | OTR | 2,084,883 | 0 | 0 | ||
| ARGENX SE | SPONSORED ADR | 04016X101 | 50,268 | 170,926 | SH | OTR | 170,926 | 0 | 0 | ||
| ASSEMBLY BIOSCIENCES INC | COM | 045396108 | 9,075 | 1,500,000 | SH | OTR | 1,500,000 | 0 | 0 | ||
| ARYA SCIENCES ACQUISTION CO | COM CL A | G31655122 | 6,510 | 600,000 | SH | OTR | 600,000 | 0 | 0 | ||
| ATRECA INC | CL A COM | 04965G109 | 35,568 | 2,202,333 | SH | OTR | 2,202,333 | 0 | 0 | ||
| AVIDITY BIOSCIENCES INC | COM | 05370A108 | 28,616 | 1,121,327 | SH | OTR | 1,121,327 | 0 | 0 | ||
| BCLS ACQUISITION CORP | COM CL A | G0904B105 | 6,005 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 287,895 | 1,114,188 | SH | OTR | 1,114,188 | 0 | 0 | ||
| BELLUS HEALTH INC NEW | COM NEW | 07987C204 | 9,104 | 2,975,000 | SH | OTR | 2,975,000 | 0 | 0 | ||
| BIOATLA INC | COM | 09077B104 | 23,343 | 686,347 | SH | OTR | 686,347 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 21,923 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| BLACK DIAMOND THERAPEUTICS I | COM | 09203E105 | 64,576 | 2,014,858 | SH | OTR | 2,014,858 | 0 | 0 | ||
| CABALETTA BIO INC | COM | 12674W109 | 20,010 | 1,603,361 | SH | OTR | 1,603,361 | 0 | 0 | ||
| CELLECTAR BIOSCIENCES INC | COM PAR | 15117F500 | 1,914 | 920,000 | SH | OTR | 920,000 | 0 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | 17,520 | 1,000,000 | SH | OTR | 1,000,000 | 0 | 0 | ||
| CEREVEL THERAPEUTICS HLDNG I | COM | 15678U128 | 11,846 | 714,500 | SH | OTR | 714,500 | 0 | 0 | ||
| CODIAK BIOSCIENCES INC | COM | 192010106 | 19,466 | 602,650 | SH | OTR | 602,650 | 0 | 0 | ||
| CONSONANCE HFW ACQUISITION C | UNIT 99/99/9999 | G2445M129 | 2,094 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| CYMABAY THERAPEUTICS INC | COM | 23257D103 | 22,960 | 4,000,000 | SH | OTR | 4,000,000 | 0 | 0 | ||
| CYTOKINETICS INC | COM NEW | 23282W605 | 43,638 | 2,100,000 | SH | OTR | 2,100,000 | 0 | 0 | ||
| DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 13,035 | 7,534,598 | SH | OTR | 7,534,598 | 0 | 0 | ||
| DIREXION SHS ETF TR | DAILY S&P BIOTEC | 25460G716 | 56,858 | 2,250,000 | SH | OTR | 2,250,000 | 0 | 0 | ||
| ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 13,000 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| FS DEV CORP | COM CL A | 303020101 | 7,700 | 700,000 | SH | OTR | 700,000 | 0 | 0 | ||
| GENOCEA BIOSCIENCES INC | COM NEW | 372427401 | 2,745 | 1,134,453 | SH | OTR | 1,134,453 | 0 | 0 | ||
| GOSSAMER BIO INC | COM | 38341P102 | 24,778 | 2,562,358 | SH | OTR | 2,562,358 | 0 | 0 | ||
| HEALTH SCIENCES ACQ CORP 2 | ORD SHS | G4411D109 | 5,124 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| HELIX ACQUISITION CORP | COM CL A | G4444C102 | 4,548 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| IDEAYA BIOSCIENCES INC | COM | 45166A102 | 30,839 | 2,202,812 | SH | OTR | 2,202,812 | 0 | 0 | ||
| ITEOS THERAPEUTICS INC | COM | 46565G104 | 146,948 | 4,345,016 | SH | OTR | 4,345,016 | 0 | 0 | ||
| JIYA ACQUISITION CORP | COM CL A | 47760M102 | 5,150 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| KADMON HLDGS INC | COM | 48283N106 | 25,754 | 6,205,882 | SH | OTR | 6,205,882 | 0 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 5,134 | 290,577 | SH | OTR | 290,577 | 0 | 0 | ||
| KINNATE BIOPHARMA INC | COM | 49705R105 | 42,352 | 1,064,665 | SH | OTR | 1,064,665 | 0 | 0 | ||
| KURA ONCOLOGY INC | COM | 50127T109 | 34,302 | 1,050,289 | SH | OTR | 1,050,289 | 0 | 0 | ||
| LA JOLLA PHARMACEUTICAL CO | COM PAR $.0001 2 | 503459604 | 3,456 | 890,700 | SH | OTR | 890,700 | 0 | 0 | ||
| LIFESCI ACQUISITION II CORP | COM | 53229E103 | 2,134 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| MARINUS PHARMACEUTICALS INC | COM NEW | 56854Q200 | 29,280 | 2,400,000 | SH | OTR | 2,400,000 | 0 | 0 | ||
| MATINAS BIOPHARMA HLDGS INC | COM | 576810105 | 15,611 | 11,478,634 | SH | OTR | 11,478,634 | 0 | 0 | ||
| MEI PHARMA INC | COM NEW | 55279B202 | 7,691 | 2,913,091 | SH | OTR | 2,913,091 | 0 | 0 | ||
| MEREO BIOPHARMA GROUP PLC | ADS | 589492107 | 22,291 | 6,226,673 | SH | OTR | 6,226,673 | 0 | 0 | ||
| MERUS N V | COM | N5749R100 | 25,030 | 1,427,849 | SH | OTR | 1,427,849 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS IN | COM | 59935V107 | 16,597 | 2,477,194 | SH | OTR | 2,477,194 | 0 | 0 | ||
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 387,788 | 1,765,560 | SH | OTR | 1,765,560 | 0 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 5,535 | 317,000 | SH | OTR | 317,000 | 0 | 0 | ||
| NEOLEUKIN THERAPEUTICS INC | COM | 64049K104 | 21,165 | 1,501,058 | SH | OTR | 1,501,058 | 0 | 0 | ||
| NURIX THERAPEUTICS INC | COM | 67080M103 | 40,274 | 1,224,892 | SH | OTR | 1,224,892 | 0 | 0 | ||
| ODONATE THERAPEUTICS INC | COM | 676079106 | 107,656 | 5,607,086 | SH | OTR | 5,607,086 | 0 | 0 | ||
| ORIC PHARMACEUTICALS INC | COM | 68622P109 | 6,770 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| PANACEA ACQUISITION CORP | CL A | 698102100 | 9,360 | 800,000 | SH | OTR | 800,000 | 0 | 0 | ||
| PANDION THERAPEUTICS INC | COM | 698340106 | 31,297 | 2,107,513 | SH | OTR | 2,107,513 | 0 | 0 | ||
| PASSAGE BIO INC | COM | 702712100 | 49,307 | 1,928,315 | SH | OTR | 1,928,315 | 0 | 0 | ||
| PMV PHARMACEUTICALS INC | COM | 69353Y103 | 139,519 | 2,268,236 | SH | OTR | 2,268,236 | 0 | 0 | ||
| POSEIDA THERAPEUTICS INC | COM | 73730P108 | 13,724 | 1,251,055 | SH | OTR | 1,251,055 | 0 | 0 | ||
| PREVAIL THERAPEUTICS INC | COM | 74140Y101 | 25,910 | 1,123,105 | SH | OTR | 1,123,105 | 0 | 0 | ||
| PROTARA THERAPEUTICS INC | COM STK | 74365U107 | 5,065 | 209,227 | SH | OTR | 209,227 | 0 | 0 | ||
| RELAY THERAPEUTICS INC | COM | 75943R102 | 53,784 | 1,294,132 | SH | OTR | 1,294,132 | 0 | 0 | ||
| REVOLUTION MEDICINES INC | COM | 76155X100 | 131,014 | 3,309,264 | SH | OTR | 3,309,264 | 0 | 0 | ||
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 80,398 | 1,466,051 | SH | OTR | 1,466,051 | 0 | 0 | ||
| SAGE THERAPEUTICS INC | COM | 78667J108 | 94,642 | 1,094,000 | SH | OTR | 1,094,000 | 0 | 0 | ||
| SEATTLE GENETICS INC | COM | 812578102 | 70,056 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| SELECTA BIOSCIENCES INC | COM | 816212104 | 9,951 | 3,284,072 | SH | OTR | 3,284,072 | 0 | 0 | ||
| SILVERBACK THERAPEUTICS INC | COM | 82835W108 | 77,637 | 1,675,377 | SH | OTR | 1,675,377 | 0 | 0 | ||
| SOLID BIOSCIENCES INC | COM | 83422E105 | 32,098 | 4,234,574 | SH | OTR | 4,234,574 | 0 | 0 | ||
| SPECTRUM PHARMACEUTICALS INC | COM | 84763A108 | 11,367 | 3,333,333 | SH | OTR | 3,333,333 | 0 | 0 | ||
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 | 150,545 | 2,075,905 | SH | OTR | 2,075,905 | 0 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | 50,880 | 2,287,782 | SH | OTR | 2,287,782 | 0 | 0 | ||
| THERAPEUTICS ACQUISITION COR | COM CL A | 88339T103 | 20,880 | 1,500,000 | SH | OTR | 1,500,000 | 0 | 0 | ||
| UNIQURE NV | SHS | N90064101 | 9,033 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| VINCERA PHARMA INC | COM | 92731L106 | 6,273 | 300,000 | SH | OTR | 300,000 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 546 | 27,300 | SH | OTR | 27,300 | 0 | 0 | ||