The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Achilles Therapeutics PLC | SPONSORED ADS | 00449L102 | 15,038 | 1,536,016 | SH | OTR | 1,536,016 | 0 | 0 | ||
| Aeglea Biotherapeutics Inc. | COM | 00773J103 | 3,828 | 550,000 | SH | OTR | 550,000 | 0 | 0 | ||
| Akero Therapeutics Inc. | COM | 00973Y108 | 20,629 | 831,495 | SH | OTR | 831,495 | 0 | 0 | ||
| Agenus Inc. | COM NEW | 00847G705 | 21,960 | 4,000,000 | SH | OTR | 4,000,000 | 0 | 0 | ||
| Aligos Therapeutics Inc. | COM | 01626L105 | 31,108 | 1,526,048 | SH | OTR | 1,526,048 | 0 | 0 | ||
| Amarin Corp PLC | SPONS ADR NEW | 023111206 | 26,280 | 6,000,000 | SH | OTR | 6,000,000 | 0 | 0 | ||
| Amicus Therapeutics Inc. | COM | 03152W109 | 22,413 | 2,325,000 | SH | OTR | 2,325,000 | 0 | 0 | ||
| Anaptys Bio Inc. | COM | 032724106 | 33,709 | 1,300,000 | SH | OTR | 1,300,000 | 0 | 0 | ||
| Arcus Biosciences Inc. | COM | 03969F109 | 57,251 | 2,084,883 | SH | OTR | 2,084,883 | 0 | 0 | ||
| ArgenX SE | SPONSORED ADR | 04016X101 | 51,461 | 170,926 | SH | OTR | 170,926 | 0 | 0 | ||
| Assembly Biosciences Inc. | COM | 045396108 | 5,820 | 1,500,000 | SH | OTR | 1,500,000 | 0 | 0 | ||
| Atreca Inc. | CL A COM | 04965G109 | 18,764 | 2,202,333 | SH | OTR | 2,202,333 | 0 | 0 | ||
| Avidity Biosciences Inc. | COM NEW | 05370A108 | 27,708 | 1,121,327 | SH | OTR | 1,121,327 | 0 | 0 | ||
| BCLS Acquisition Corp | COM CL A | G0904B105 | 5,265 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| BeiGene Ltd | SPONSORED ADR | 07725L102 | 262,262 | 764,188 | SH | OTR | 764,188 | 0 | 0 | ||
| Bellus Health Inc. | COM NEW | 07987C204 | 9,252 | 2,975,000 | SH | OTR | 2,975,000 | 0 | 0 | ||
| BioAtla Inc. | COM | 09077B104 | 29,087 | 686,347 | SH | OTR | 686,347 | 0 | 0 | ||
| Biomarin Pharmaceutical Inc. | COM | 09061G101 | 20,860 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| Biomea Fusion Inc. | COM | 09077A106 | 32,600 | 2,088,405 | SH | OTR | 2,088,405 | 0 | 0 | ||
| Black Diamond Therapeutics Inc. | COM | 09203E105 | 24,561 | 2,014,858 | SH | OTR | 2,014,858 | 0 | 0 | ||
| Bolt Biotherapeutics Inc. | COM | 097702104 | 773 | 50,000 | SH | OTR | 50,000 | 0 | 0 | ||
| Cabaletta Bio Inc. | COM | 12674W109 | 13,789 | 1,603,361 | SH | OTR | 1,603,361 | 0 | 0 | ||
| Catabasis Pharmaceuticals Inc. | COM NEW | 14875P206 | 3,745 | 1,775,000 | SH | OTR | 1,775,000 | 0 | 0 | ||
| Cellectar Biosciences Inc. | COM PAR | 15117F500 | 1,095 | 920,000 | SH | OTR | 920,000 | 0 | 0 | ||
| Centessa Pharmaceuticals PLC | SPONSORED ADS | 152309100 | 20,083 | 904,227 | SH | OTR | 904,227 | 0 | 0 | ||
| Cerevel Therapeutics Holding Inc. | COM CL A | 15678U128 | 18,305 | 714,500 | SH | OTR | 714,500 | 0 | 0 | ||
| Codiak Biosciences Inc. | COM | 192010106 | 19,087 | 1,030,065 | SH | OTR | 1,030,065 | 0 | 0 | ||
| Connect Biopharma Holdings Ltd. | ADS | 207523101 | 40,648 | 2,081,323 | SH | OTR | 2,081,323 | 0 | 0 | ||
| Consonance HFW Acquisition Corp | UNIT 99/99/9999 | G2445M129 | 2,042 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| Cullinan Oncology Inc. | COM | 230031106 | 27,658 | 1,074,082 | SH | OTR | 1,074,082 | 0 | 0 | ||
| Cymabay Therapeutics Inc. | COM | 23257D103 | 17,440 | 4,000,000 | SH | OTR | 4,000,000 | 0 | 0 | ||
| Cytokinetics Inc. | COM NEW | 23282W605 | 41,559 | 2,100,000 | SH | OTR | 2,100,000 | 0 | 0 | ||
| Day One Biopharmaceuticals Inc. | COM | 23954D109 | 27,095 | 1,189,943 | SH | OTR | 1,189,943 | 0 | 0 | ||
| DBV Technologies SA | SPONSORED ADR | 23306J101 | 41,214 | 7,534,598 | SH | OTR | 7,534,598 | 0 | 0 | ||
| Elevation Oncology Inc. | COM | 28623U101 | 18,205 | 1,341,530 | SH | OTR | 1,341,530 | 0 | 0 | ||
| Esperion Therapeutics Inc. | COM | 29664W105 | 10,575 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| Essa Pharma Inc. | COM | 29668H708 | 19,628 | 687,000 | SH | OTR | 687,000 | 0 | 0 | ||
| F-Star Therapeutics Inc. | COM | 30315R107 | 15,045 | 1,751,428 | SH | OTR | 1,751,428 | 0 | 0 | ||
| Gemini Therapeutics Inc. | COM | 36870G105 | 8,411 | 1,300,000 | SH | OTR | 1,300,000 | 0 | 0 | ||
| Genocea Biosciences Inc. | COM NEW | 372427401 | 2,655 | 1,134,453 | SH | OTR | 1,134,453 | 0 | 0 | ||
| GH Research PLC | ORDINARY SHARES | G3855L106 | 22,021 | 1,013,399 | SH | OTR | 1,013,399 | 0 | 0 | ||
| Gossamer Bio Inc. | COM | 38341P102 | 20,806 | 2,562,358 | SH | OTR | 2,562,358 | 0 | 0 | ||
| Health Sciences Acquisition Corp II | ORD SHS | G4411D109 | 4,080 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| Helix Acquisition Corp | COM CL A | G4444C102 | 4,132 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| Ideaya Biosciences Inc. | COM | 45166A102 | 46,237 | 2,202,812 | SH | OTR | 2,202,812 | 0 | 0 | ||
| Immunovant Inc. | COM | 45258J102 | 10,570 | 1,000,000 | SH | OTR | 1,000,000 | 0 | 0 | ||
| Immutep Ltd. | SPONSORED ADS | 45257L108 | 9,675 | 2,500,000 | SH | OTR | 2,500,000 | 0 | 0 | ||
| iTeos Therapeutics Inc. | COM | 46565G104 | 111,450 | 4,345,016 | SH | OTR | 4,345,016 | 0 | 0 | ||
| JIYA Acquisition Corp | COM CL A | 47760M102 | 4,970 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| Kadmon Holdings Inc. | COM | 48283N106 | 24,017 | 6,205,882 | SH | OTR | 6,205,882 | 0 | 0 | ||
| Kiniksa Pharmaceuticals Ltd. | COM CL A | G5269C101 | 4,048 | 290,577 | SH | OTR | 290,577 | 0 | 0 | ||
| Kinnate Biopharma Inc. | COM | 49705R105 | 24,815 | 1,065,939 | SH | OTR | 1,065,939 | 0 | 0 | ||
| Kura Oncology Inc. | COM | 50127T109 | 21,899 | 1,050,289 | SH | OTR | 1,050,289 | 0 | 0 | ||
| La Jolla Pharmaceutical Co. | COM PAR $.0001 2 | 503459604 | 3,812 | 890,700 | SH | OTR | 890,700 | 0 | 0 | ||
| Lifesci Acquisition II Corp | COM | 53229E103 | 2,000 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| Marinus Pharmaceuticals Inc. | COM NEW | 56854Q200 | 43,056 | 2,400,000 | SH | OTR | 2,400,000 | 0 | 0 | ||
| Matinas Biopharma Holdings Inc. | COM | 576810105 | 8,895 | 11,478,634 | SH | OTR | 11,478,634 | 0 | 0 | ||
| MEI Pharma Inc. | COM NEW | 55279B202 | 8,302 | 2,913,091 | SH | OTR | 2,913,091 | 0 | 0 | ||
| Mereo Biopharma Group PLC | ADS | 589492107 | 19,739 | 6,226,673 | SH | OTR | 6,226,673 | 0 | 0 | ||
| Merus NV | COM | N5749R100 | 40,033 | 1,900,000 | SH | OTR | 1,900,000 | 0 | 0 | ||
| Milestone Pharmaceuticals Inc. | COM | 59935V107 | 14,147 | 2,572,194 | SH | OTR | 2,572,194 | 0 | 0 | ||
| Mirati Therapeutics Inc. | COM | 60468T105 | 323,060 | 2,000,000 | SH | OTR | 2,000,000 | 0 | 0 | ||
| Mirum Pharmaceuticals Inc. | COM | 604749101 | 5,481 | 317,000 | SH | OTR | 317,000 | 0 | 0 | ||
| Nautilus Biotechnology Inc. | COM | 63909J108 | 7,575 | 750,000 | SH | OTR | 750,000 | 0 | 0 | ||
| Neoleukin Therapeutics Inc. | COM | 64049K104 | 13,855 | 1,501,058 | SH | OTR | 1,501,058 | 0 | 0 | ||
| NGM Biopharmaceuticals Inc. | COM | 62921N105 | 9,860 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| Nurix Therapeutics Inc. | COM | 67080M103 | 32,496 | 1,224,892 | SH | OTR | 1,224,892 | 0 | 0 | ||
| Nuvation Bio Inc. | COM CL A | 67080N101 | 40,415 | 4,341,009 | SH | OTR | 4,341,009 | 0 | 0 | ||
| Nuvation Bio Inc. | W EXP 07/07/202 | 67080N119 | 693 | 266,666 | SH | OTR | 266,666 | 0 | 0 | ||
| Odonate Therapeutics Inc. | COM | 676079106 | 19,569 | 5,607,086 | SH | OTR | 5,607,086 | 0 | 0 | ||
| Omega Alpha SPAC | CL A | G6749V107 | 1,990 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| Oric Pharmaceuticals Inc. | COM | 68622P109 | 3,538 | 200,000 | SH | OTR | 200,000 | 0 | 0 | ||
| Panacea Acquisition Corp II | CL A SHS | G6882C106 | 5,010 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| Passage Bio Inc. | COM | 702712100 | 25,531 | 1,928,315 | SH | OTR | 1,928,315 | 0 | 0 | ||
| PMV Pharmaceuticals Inc. | COM | 69353Y103 | 77,483 | 2,268,236 | SH | OTR | 2,268,236 | 0 | 0 | ||
| Poseida Therapeutics Inc. | COM | 73730P108 | 12,536 | 1,251,055 | SH | OTR | 1,251,055 | 0 | 0 | ||
| Protara Therapeutics Inc. | COM STK | 74365U107 | 2,038 | 209,227 | SH | OTR | 209,227 | 0 | 0 | ||
| Rain Therapeutics Inc. | COM | 75082Q105 | 18,260 | 1,175,000 | SH | OTR | 1,175,000 | 0 | 0 | ||
| Relay Therapeutics Inc. | COM | 75943R102 | 47,352 | 1,294,132 | SH | OTR | 1,294,132 | 0 | 0 | ||
| Research Alliance Corp II | COM CL A | 760873109 | 5,070 | 500,000 | SH | OTR | 500,000 | 0 | 0 | ||
| Revolution Medicines Inc. | COM | 76155X100 | 110,591 | 3,484,264 | SH | OTR | 3,484,264 | 0 | 0 | ||
| Rocket Pharmaceuticals Inc. | COM | 77313F106 | 64,931 | 1,466,051 | SH | OTR | 1,466,051 | 0 | 0 | ||
| Sage Therapeutics Inc. | COM | 78667J108 | 62,150 | 1,094,000 | SH | OTR | 1,094,000 | 0 | 0 | ||
| Seagen Inc. | COM | 81181C104 | 63,152 | 400,000 | SH | OTR | 400,000 | 0 | 0 | ||
| Selecta Biosciences Inc. | COM | 816212104 | 13,727 | 3,284,072 | SH | OTR | 3,284,072 | 0 | 0 | ||
| Silverback Therapeutics Inc. | COM | 82835W108 | 51,752 | 1,675,377 | SH | OTR | 1,675,377 | 0 | 0 | ||
| Solid Biosciences Inc. | COM | 83422E105 | 15,499 | 4,234,574 | SH | OTR | 4,234,574 | 0 | 0 | ||
| Springworks Therapeutics Inc. | COM | 85205L107 | 171,075 | 2,075,905 | SH | OTR | 2,075,905 | 0 | 0 | ||
| Syndax Pharmaceuticals Inc. | COM | 87164F105 | 39,281 | 2,287,782 | SH | OTR | 2,287,782 | 0 | 0 | ||
| Talis Biomedical Corp. | COM | 87424L108 | 17,108 | 1,550,998 | SH | OTR | 1,550,998 | 0 | 0 | ||
| Therapeutics Acquisition Corp | COM CL A | 88339T103 | 25,675 | 2,500,000 | SH | OTR | 2,500,000 | 0 | 0 | ||
| UniQure NV | SHS | N90064101 | 7,700 | 250,000 | SH | OTR | 250,000 | 0 | 0 | ||
| VincerX Pharma Inc. | COM NEW | 92731L106 | 5,846 | 450,000 | SH | OTR | 450,000 | 0 | 0 | ||
| Xenon Pharmaceuticals Inc. | COM | 98420N105 | 15,957 | 857,000 | SH | OTR | 857,000 | 0 | 0 | ||
| Zogenix Inc. | COM NEW | 98978L204 | 472 | 27,300 | SH | OTR | 27,300 | 0 | 0 | ||