JOINT FILING AGREEMENT
The undersigned hereby agree that the Statement on Schedule 13G with respect to the common stock of The Medicines Company, par value $0.001 per share, is, and any amendments thereto executed by each of us shall be, filed on behalf of each of us pursuant to and in accordance with the provisions ofRule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, and that this Agreement shall be included as an Exhibit to the Schedule 13G and each such amendment. Each of the undersigned agrees to be responsible for the timely filing of the Schedule 13G and any amendments thereto, and for the completeness and accuracy of the information concerning itself contained therein. This Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.
IN WITNESS WHEREOF, the undersigned have executed this Agreement as of February 14, 2019.
| BOXER CAPITAL, LLC | ||
| By: | /s/ Aaron I. Davis | |
| Name: | Aaron I. Davis | |
| Title: | Authorized Signatory | |
| BOXER ASSET MANAGEMENT INC. | ||
| By: | /s/ Jason Callender | |
| Name: | Jason Callender | |
| Title: | Director | |
| BRASLYN LTD. | ||
| By: | /s/ Joseph C. Lewis | |
| Name: | Joseph C. Lewis | |
| Title: | Director | |
| AVID GROUP LTD. | ||
| By: | /s/ Joseph C. Lewis | |
| Name: | Joseph C. Lewis | |
| Title: | Director | |
| TUESDAY THIRTEEN INC. | ||
| By: | /s/ Joseph C. Lewis | |
| Name: | Joseph C. Lewis | |
| Title: | Director | |
| JOSEPH C. LEWIS | ||
/s/ Joseph C. Lewis | ||
| Joseph C. Lewis, Individually | ||